Cel (carboxyl ester lipase) - Rat Genome Database

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Gene: Cel (carboxyl ester lipase) Rattus norvegicus
Symbol: Cel
Name: carboxyl ester lipase
RGD ID: 2331
Description: Enables carboxylic ester hydrolase activity and glycosphingolipid binding activity. Predicted to be involved in ceramide catabolic process; intestinal cholesterol absorption; and pancreatic juice secretion. Located in extracellular space and zymogen granule. Part of protein-containing complex. Human ortholog(s) of this gene implicated in lipomatosis; maturity-onset diabetes of the young type 8; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human CEL (carboxyl ester lipase); PARTICIPATES IN glycerolipid metabolic pathway; steroid biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Bal; bile salt-activated lipase; bile salt-stimulated lipase; Bssl; cholesterol esterase; pancreatic lysophospholipase; sterol esterase
RGD Orthologs
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2311,883,532 - 11,891,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,883,532 - 11,891,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx314,955,824 - 14,963,304 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,540,779 - 23,548,259 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,795,231 - 21,802,711 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,134,021 - 7,141,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,134,021 - 7,141,522 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,485,038 - 12,492,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,541,127 - 7,549,245 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,541,429 - 7,549,545 (-)NCBI
Celera36,664,206 - 6,672,217 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-ethoxyethanol  (EXP)
2-methoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-nitrophenyl acetate  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
cyclophosphamide  (ISO)
deguelin  (ISO)
dextran sulfate  (ISO)
dihydroxyacetone  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenpyroximate  (ISO)
ferroheme b  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
heme b  (EXP)
hydralazine  (ISO)
irinotecan  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isotretinoin  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-N-nitrosourea  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
orlistat  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
senecionine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sunitinib  (ISO)
taurocholic acid  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
valproic acid  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View

References - curated
# Reference Title Reference Citation
1. The combinatorial extension method reveals a sphingolipid binding domain on pancreatic bile salt-dependent lipase: role in secretion. Aubert-Jousset E, etal., Structure. 2004 Aug;12(8):1437-47.
2. Participation of GRP94-related protein in secretion of pancreatic bile salt-dependent lipase and in its internalization by the intestinal epithelium. Bruneau N, etal., J Cell Sci. 1998 Sep;111 ( Pt 17):2665-79.
3. Pancreatic bile-salt-dependent lipase activity in serum of diabetic patients: is there a relationship with glycation? Caillol N, etal., Clin Sci (Lond). 1998 Feb;94(2):181-8.
4. Identity of a cytosolic neutral cholesterol esterase in rat liver with the bile salt stimulated cholesterol esterase in pancreas. Camulli ED, etal., Biochim Biophys Acta. 1989 Sep 25;1005(2):177-82.
5. Site-specific mutagenesis of an essential histidine residue in pancreatic cholesterol esterase. DiPersio LP, etal., J Biol Chem 1991 Mar 5;266(7):4033-6.
6. Decrease in contents of pancreatic carboxyl ester lipase, phospholipase A2, and lingual lipase in rats with streptozotocin-induced diabetes. Duan RD and Sternby B, Scand J Gastroenterol. 1993 Mar;28(3):256-60.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Isolation of full-length putative rat lysophospholipase cDNA using improved methods for mRNA isolation and cDNA cloning. Han JH, etal., Biochemistry 1987 Mar 24;26(6):1617-25.
10. Size of the catalytically active unit of rat hepatic carboxylester lipase in the presence and absence of bile salt. Harrison EH, etal., Biochim Biophys Acta. 1997 Aug 16;1347(2-3):177-82.
11. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
12. Molecular cloning and expression of cDNA for rat pancreatic cholesterol esterase. Kissel JA, etal., Biochim Biophys Acta 1989 Nov 28;1006(2):227-36.
13. Impairment of bile salt-dependent lipase secretion in AR4-2J rat pancreatic cells induces its degradation by the proteasome. Le Petit-Thevenin J, etal., Biochim Biophys Acta. 2001 Feb 26;1530(2-3):184-98.
14. Importance of arginines 63 and 423 in modulating the bile salt-dependent and bile salt-independent hydrolytic activities of rat carboxyl ester lipase. Liang Y, etal., J Biol Chem. 2000 Aug 4;275(31):24040-6.
15. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
18. Circulating antibodies against an exocrine pancreatic enzyme in type 1 diabetes. Panicot L, etal., Diabetes. 1999 Dec;48(12):2316-23.
19. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
20. Pancreatic lipomatosis is a structural marker in nondiabetic children with mutations in carboxyl-ester lipase. Raeder H, etal., Diabetes. 2007 Feb;56(2):444-9.
21. Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. Raeder H, etal., Nat Genet. 2006 Jan;38(1):54-62. Epub 2005 Dec 20.
22. GOA pipeline RGD automated data pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:1854805   PMID:2069957   PMID:2211595   PMID:9160047   PMID:11733511   PMID:12031288   PMID:15265857   PMID:16502470   PMID:17805199   PMID:23376485   PMID:23533145  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2311,883,532 - 11,891,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,883,532 - 11,891,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx314,955,824 - 14,963,304 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,540,779 - 23,548,259 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,795,231 - 21,802,711 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,134,021 - 7,141,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,134,021 - 7,141,522 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,485,038 - 12,492,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,541,127 - 7,549,245 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,541,429 - 7,549,545 (-)NCBI
Celera36,664,206 - 6,672,217 (-)NCBICelera
Cytogenetic Map3p12NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389133,061,981 - 133,071,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9133,061,981 - 133,071,861 (+)EnsemblGRCh38hg38GRCh38
GRCh379135,937,368 - 135,947,248 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,927,186 - 134,937,069 (+)NCBINCBI36Build 36hg18NCBI36
Build 349132,966,918 - 132,976,801NCBI
Celera9106,479,095 - 106,504,472 (+)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,431,068 - 105,440,909 (+)NCBIHuRef
CHM1_19136,087,941 - 136,097,924 (+)NCBICHM1_1
T2T-CHM13v2.09145,276,137 - 145,285,985 (+)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39228,445,831 - 28,453,415 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,445,807 - 28,453,415 (-)EnsemblGRCm39 Ensembl
GRCm38228,555,819 - 28,563,403 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,555,795 - 28,563,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv37228,411,339 - 28,418,882 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,377,828 - 28,385,371 (-)NCBIMGSCv36mm8
Celera228,259,995 - 28,267,538 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0NW_0049555132,324,025 - 2,382,877 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan196,287,257 - 6,297,627 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,180,310 - 104,191,434 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,809,606 - 132,821,010 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,810,986 - 132,821,010 (+)Ensemblpanpan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1951,337,205 - 51,345,284 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,337,187 - 51,362,422 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,600,407 - 50,608,486 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,230,487 - 52,238,498 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,230,540 - 52,255,656 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,009,024 - 51,017,035 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,333,616 - 51,341,559 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,412,863 - 51,420,943 (-)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024404947199,691,971 - 199,702,102 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,463,182 - 19,469,900 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648719,463,219 - 19,472,029 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1272,763,003 - 272,770,255 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,763,203 - 272,770,259 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,719,658 - 306,726,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1125,053,817 - 5,077,487 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,066,882 - 5,077,227 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,574,982 - 10,585,407 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Variants in Cel
24 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:42
Interacting mature miRNAs:47
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2311,884,712 - 11,884,828 (+)MAPPERmRatBN7.2
Rnor_6.037,135,202 - 7,135,317NCBIRnor6.0
Rnor_5.0312,486,219 - 12,486,334UniSTSRnor5.0
RGSC_v3.437,542,304 - 7,542,420RGDRGSC3.4
RGSC_v3.437,542,305 - 7,542,420UniSTSRGSC3.4
RGSC_v3.137,542,604 - 7,542,720RGD
Celera36,666,010 - 6,666,125UniSTS
RH 3.4 Map321.8UniSTS
RH 3.4 Map321.8RGD
Cytogenetic Map3p12UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.037,140,238 - 7,140,570NCBIRnor6.0
Rnor_5.0312,491,255 - 12,491,693UniSTSRnor5.0
RGSC_v3.437,547,341 - 7,548,297UniSTSRGSC3.4
Celera36,671,047 - 6,671,265UniSTS
RH 3.4 Map321.9RGD
RH 3.4 Map321.9UniSTS
SHRSP x BN Map32.2899UniSTS
SHRSP x BN Map32.2899RGD
Cytogenetic Map3p12UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2311,885,366 - 11,885,686 (+)MAPPERmRatBN7.2
Rnor_6.037,135,856 - 7,136,175NCBIRnor6.0
Rnor_5.0312,486,873 - 12,487,192UniSTSRnor5.0
RGSC_v3.437,542,959 - 7,543,278UniSTSRGSC3.4
Celera36,666,664 - 6,666,984UniSTS
RH 3.4 Map321.8UniSTS
Cytogenetic Map3p12UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2
Medium 7 6 7 6
Low 2 11 17 5 9 5 5 6 52 18 32 11 5
Below cutoff 1 32 33 30 1 30 3 5 22 17 7 3


RefSeq Acc Id: ENSRNOT00000014572   ⟹   ENSRNOP00000014572
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl311,883,532 - 11,891,035 (-)Ensembl
Rnor_6.0 Ensembl37,134,021 - 7,141,522 (-)Ensembl
RefSeq Acc Id: NM_016997   ⟹   NP_058693
RefSeq Status: VALIDATED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2311,883,532 - 11,891,035 (-)NCBI
Rnor_6.037,134,021 - 7,141,522 (-)NCBI
Rnor_5.0312,485,038 - 12,492,645 (-)NCBI
RGSC_v3.437,541,127 - 7,549,245 (-)RGD
Celera36,664,206 - 6,672,217 (-)NCBI
RefSeq Acc Id: NP_058693   ⟸   NM_016997
- Peptide Label: precursor
- UniProtKB: P14722 (UniProtKB/Swiss-Prot),   P07882 (UniProtKB/Swiss-Prot),   G3V7G2 (UniProtKB/TrEMBL),   A6JTP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014572   ⟸   ENSRNOT00000014572
Protein Domains
Carboxylesterase type B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P07882-F1-model_v2 AlphaFold P07882 1-612 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2331 AgrOrtholog
BioCyc Gene G2FUF-50278 BioCyc
Ensembl Genes ENSRNOG00000010406 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014572 ENTREZGENE
  ENSRNOP00000014572.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014572 ENTREZGENE
  ENSRNOT00000014572.5 UniProtKB/TrEMBL
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CarbesteraseB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carboxylesterase_B_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carboxylesterase_B_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24254 UniProtKB/TrEMBL
  PTHR43903:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COesterase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cel PhenoGen
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CEL_RAT UniProtKB/Swiss-Prot
UniProt Secondary P14722 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Cel  Carboxyl ester lipase      Symbol and Name status set to approved 70586 APPROVED