Slc16a1 (solute carrier family 16 member 1) - Rat Genome Database

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Gene: Slc16a1 (solute carrier family 16 member 1) Rattus norvegicus
Analyze
Symbol: Slc16a1
Name: solute carrier family 16 member 1
RGD ID: 3690
Description: Enables identical protein binding activity; monocarboxylic acid transmembrane transporter activity; and organic cyclic compound binding activity. Involved in cellular response to organic cyclic compound and plasma membrane lactate transport. Located in apical plasma membrane and basolateral plasma membrane. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7. Orthologous to human SLC16A1 (solute carrier family 16 member 1); INTERACTS WITH (+)-schisandrin B; (S)-mandelic acid; (S)-naringenin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MCT 1; MCT1; monocarboxylate transporter 1; RATMCT1; RNMCT1; solute carrier 16 (monocarboxylic acid transporter) member 1; solute carrier 16 (monocarboxylic acid transporter), member 1; solute carrier family 16 (monocarboxylate transporter), member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; solute carrier family 16, member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22192,123,755 - 192,144,617 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2192,124,289 - 192,144,611 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2199,718,059 - 199,737,573 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02197,590,762 - 197,610,276 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02192,407,716 - 192,427,233 (+)NCBIRnor_WKY
Rnor_6.02207,108,552 - 207,129,352 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2207,108,552 - 207,128,554 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02226,529,294 - 226,549,303 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42199,860,341 - 199,879,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12199,823,090 - 199,843,400 (+)NCBI
Celera2184,591,461 - 184,610,976 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(S)-mandelic acid  (EXP)
(S)-naringenin  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrophenol  (ISO)
2-hydroxypropanoic acid  (EXP,ISO)
2-oxobutanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-bromopyruvic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-Nitro-2-(3-phenylpropylamino)benzoic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinoic acid  (ISO)
acetaldehyde  (ISO)
acetate ester  (ISO)
acetic acid  (EXP)
acetylsalicylic acid  (ISO)
alachlor  (EXP)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
apigenin  (EXP)
aristolochic acid  (ISO)
benzalkonium chloride  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzoic acid  (EXP,ISO)
beta-naphthoflavone  (EXP)
biochanin A  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butyric acid  (EXP)
cadmium atom  (ISO)
caffeine  (ISO)
choline  (ISO)
chrysin  (EXP)
ciprofibrate  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
Clofop  (ISO)
curcumin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
decabromodiphenyl ether  (EXP)
deoxynivalenol  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
dichlorine  (EXP)
dichloroacetic acid  (ISO)
dieldrin  (EXP)
diosmetin  (EXP)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
fisetin  (EXP)
fluoranthene  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
formic acid  (ISO)
fulvestrant  (EXP)
geldanamycin  (ISO)
genistein  (EXP,ISO)
genistein 7-O-beta-D-glucoside  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycitein  (ISO)
glycitin  (ISO)
heptachlor  (EXP)
hesperetin  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
josamycin  (ISO)
kaempferol  (EXP,ISO)
L-1,4-dithiothreitol  (ISO)
L-methionine  (ISO)
luteolin  (EXP)
mandelic acid  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (EXP)
mirex  (EXP)
morin  (EXP,ISO)
motexafin gadolinium  (ISO)
N-ethylmaleimide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
nicotinic acid  (EXP)
nitrofen  (EXP)
ouabain  (ISO)
oxaliplatin  (EXP)
oxycodone  (EXP)
ozone  (EXP)
p-chloromercuribenzenesulfonic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phloretin  (EXP)
phosphonoformic acid  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP)
propionic acid  (EXP)
pyruvic acid  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (EXP,ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP)
salicylic acid  (EXP,ISO)
SB 431542  (ISO)
silibinin  (ISO)
sirolimus  (EXP)
sodium arsenite  (ISO)
sodium azide  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
topiramate  (EXP)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zinc acetate  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. Bröer S, etal., Biochem J. 1998 Jul 1;333 ( Pt 1):167-74. doi: 10.1042/bj3330167.
2. Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons. Bröer S, etal., J Biol Chem. 1997 Nov 28;272(48):30096-102. doi: 10.1074/jbc.272.48.30096.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex. Hashimoto T, etal., Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1237-44. Epub 2006 Jan 24.
6. cDNA cloning of MCT1, a monocarboxylate transporter from rat skeletal muscle. Jackson VN, etal., Biochim Biophys Acta 1995 Sep 13;1238(2):193-6.
7. Functional clarification of MCT1-mediated transport of monocarboxylic acids at the blood-brain barrier using in vitro cultured cells and in vivo BUI studies. Kido Y, etal., Pharm Res. 2000 Jan;17(1):55-62. doi: 10.1023/a:1007518525161.
8. In situ analysis of mTORC1/2 and cellular metabolism-related proteins in human Lymphangioleiomyomatosis. Krencz I, etal., Hum Pathol. 2018 Sep;79:199-207. doi: 10.1016/j.humpath.2018.05.018. Epub 2018 Jun 6.
9. The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity. Manoharan C, etal., Mol Membr Biol. 2006 Nov-Dec;23(6):486-98.
10. Changes in MCT 1, MCT 4, and LDH expression are tissue specific in rats after long-term hypobaric hypoxia. McClelland GB and Brooks GA, J Appl Physiol 2002 Apr;92(4):1573-84.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. A monocarboxylate transporter MCT1 is located at the basolateral pole of rat jejunum. Orsenigo MN, etal., Exp Physiol. 1999 Nov;84(6):1033-42.
15. AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. Ovens MJ, etal., Biochem J. 2010 Jan 15;425(3):523-30. doi: 10.1042/BJ20091515.
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation. Roberts LM, etal., Neuroscience. 2008 Aug 13;155(2):423-38. Epub 2008 Jun 13.
20. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
21. cDNA cloning and functional characterization of rat intestinal monocarboxylate transporter. Takanaga H, etal., Biochem Biophys Res Commun 1995 Dec 5;217(1):370-7.
22. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
23. Muscle contraction increases lactate transport while reducing sarcolemmal MCT4, but not MCT1. Tonouchi M, etal., Am J Physiol Endocrinol Metab 2002 May;282(5):E1062-9.
24. Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ. Wilson MC, etal., J Biol Chem. 2002 Feb 1;277(5):3666-72. Epub 2001 Nov 21.
25. Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle. Wilson MC, etal., J Biol Chem. 2009 Jul 24;284(30):20011-21. doi: 10.1074/jbc.M109.014217. Epub 2009 May 27.
Additional References at PubMed
PMID:12611763   PMID:12900382   PMID:12946269   PMID:12966567   PMID:14534079   PMID:14729246   PMID:15388779   PMID:15390096   PMID:15489334   PMID:15505343   PMID:15572359   PMID:15917240  
PMID:15932892   PMID:16174776   PMID:16301311   PMID:16396499   PMID:16446038   PMID:16516162   PMID:16959859   PMID:17609257   PMID:18375207   PMID:18523157   PMID:18614015   PMID:19118535  
PMID:19168540   PMID:19401710   PMID:19433117   PMID:19946888   PMID:20458337   PMID:21192921   PMID:21297988   PMID:21376239   PMID:21512297   PMID:21605500   PMID:21624469   PMID:21741392  
PMID:21856423   PMID:22522610   PMID:22871113   PMID:22925948   PMID:23344966   PMID:23816619   PMID:23886299   PMID:24367518   PMID:24390345   PMID:24454947   PMID:24610532   PMID:24854892  
PMID:26037401   PMID:26316108   PMID:26831515   PMID:26872974   PMID:26996590   PMID:27026010   PMID:27982679   PMID:29205833   PMID:29249221   PMID:29572438   PMID:31578706   PMID:33625690  
PMID:33999492   PMID:34874512  


Genomics

Comparative Map Data
Slc16a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22192,123,755 - 192,144,617 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2192,124,289 - 192,144,611 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2199,718,059 - 199,737,573 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02197,590,762 - 197,610,276 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02192,407,716 - 192,427,233 (+)NCBIRnor_WKY
Rnor_6.02207,108,552 - 207,129,352 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2207,108,552 - 207,128,554 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02226,529,294 - 226,549,303 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42199,860,341 - 199,879,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12199,823,090 - 199,843,400 (+)NCBI
Celera2184,591,461 - 184,610,976 (+)NCBICelera
Cytogenetic Map2q34NCBI
SLC16A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381112,911,847 - 112,956,196 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1112,911,847 - 112,957,593 (-)EnsemblGRCh38hg38GRCh38
GRCh371113,454,469 - 113,498,818 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361113,255,992 - 113,300,498 (-)NCBINCBI36Build 36hg18NCBI36
Build 341113,166,895 - 113,210,847NCBI
Celera1111,683,316 - 111,727,817 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1111,313,328 - 111,357,846 (-)NCBIHuRef
CHM1_11113,569,526 - 113,614,046 (-)NCBICHM1_1
T2T-CHM13v2.01112,924,405 - 112,968,780 (-)NCBIT2T-CHM13v2.0
Slc16a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393104,545,980 - 104,565,778 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3104,545,984 - 104,565,778 (+)EnsemblGRCm39 Ensembl
GRCm383104,638,664 - 104,658,462 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3104,638,668 - 104,658,462 (+)EnsemblGRCm38mm10GRCm38
MGSCv373104,442,591 - 104,462,385 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363104,767,729 - 104,787,523 (+)NCBIMGSCv36mm8
Celera3106,835,859 - 106,855,656 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
Slc16a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543516,334,793 - 16,342,552 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543516,334,382 - 16,361,737 (-)NCBIChiLan1.0ChiLan1.0
SLC16A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11124,755,250 - 124,800,032 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1124,755,250 - 124,800,032 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01115,555,561 - 115,600,302 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC16A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11762,636,600 - 62,690,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1762,622,902 - 62,787,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1762,150,910 - 62,209,599 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01763,810,274 - 63,868,497 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1763,815,622 - 63,983,167 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11762,545,706 - 62,604,231 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01762,603,038 - 62,661,526 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01763,362,876 - 63,421,192 (+)NCBIUU_Cfam_GSD_1.0
LOC101966363
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505816,016,206 - 16,029,442 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366901,448,289 - 1,461,525 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC16A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4107,494,463 - 107,641,703 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14107,510,920 - 107,547,609 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24117,603,634 - 117,614,944 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC16A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12020,694,222 - 20,741,542 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2020,727,199 - 20,739,979 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603823,493,479 - 23,537,747 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Position Markers
D2Wox36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,143,218 - 192,143,436 (+)MAPPERmRatBN7.2
Rnor_6.02207,127,954 - 207,128,171NCBIRnor6.0
Rnor_5.02226,548,696 - 226,548,913UniSTSRnor5.0
RGSC_v3.42199,879,249 - 199,879,466UniSTSRGSC3.4
Celera2184,610,369 - 184,610,586UniSTS
Cytogenetic Map2q34UniSTS
RH132318  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,143,478 - 192,143,696 (+)MAPPERmRatBN7.2
Rnor_6.02207,128,214 - 207,128,431NCBIRnor6.0
Rnor_5.02226,548,956 - 226,549,173UniSTSRnor5.0
RGSC_v3.42199,879,509 - 199,879,726UniSTSRGSC3.4
Celera2184,610,629 - 184,610,846UniSTS
RH 3.4 Map21342.0UniSTS
Cytogenetic Map2q34UniSTS
RH129106  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,144,398 - 192,144,579 (+)MAPPERmRatBN7.2
Rnor_6.02207,129,134 - 207,129,314NCBIRnor6.0
Rnor_5.02226,549,876 - 226,550,056UniSTSRnor5.0
RGSC_v3.42199,880,429 - 199,880,609UniSTSRGSC3.4
Celera2184,611,549 - 184,611,729UniSTS
RH 3.4 Map21342.0UniSTS
Cytogenetic Map2q34UniSTS
RH131856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,143,959 - 192,144,148 (+)MAPPERmRatBN7.2
Rnor_6.02207,128,695 - 207,128,883NCBIRnor6.0
Rnor_5.02226,549,437 - 226,549,625UniSTSRnor5.0
RGSC_v3.42199,879,990 - 199,880,178UniSTSRGSC3.4
Celera2184,611,110 - 184,611,298UniSTS
RH 3.4 Map21342.1UniSTS
Cytogenetic Map2q34UniSTS
Slc16a1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,139,990 - 192,140,682 (+)MAPPERmRatBN7.2
Rnor_6.02207,124,231 - 207,124,922NCBIRnor6.0
Rnor_5.02226,544,973 - 226,545,664UniSTSRnor5.0
RGSC_v3.42199,876,021 - 199,876,712UniSTSRGSC3.4
Celera2184,607,141 - 184,607,832UniSTS
Cytogenetic Map2q34UniSTS
BI294019  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,123,401 - 192,123,552 (+)MAPPERmRatBN7.2
Rnor_6.02207,107,645 - 207,107,795NCBIRnor6.0
Rnor_5.02226,528,387 - 226,528,537UniSTSRnor5.0
RGSC_v3.42199,859,434 - 199,859,584UniSTSRGSC3.4
Celera2184,590,554 - 184,590,704UniSTS
RH 3.4 Map21345.0UniSTS
Cytogenetic Map2q34UniSTS
AI008262  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22192,144,625 - 192,144,834 (+)MAPPERmRatBN7.2
Rnor_6.02207,129,361 - 207,129,569NCBIRnor6.0
Rnor_5.02226,550,103 - 226,550,311UniSTSRnor5.0
RGSC_v3.42199,880,656 - 199,880,864UniSTSRGSC3.4
Celera2184,611,776 - 184,611,984UniSTS
RH 3.4 Map10580.9UniSTS
Cytogenetic Map2q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
4889834Pur24Proteinuria QTL 245.80.014total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2184114274202447032Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
7488929Bp366Blood pressure QTL 3660.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2184974550193094998Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2185876309219753474Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2189599258218414891Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2190602746192625452Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2190602746192625452Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:697
Count of miRNA genes:322
Interacting mature miRNAs:427
Transcripts:ENSRNOT00000027234
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 34 40 10 8
Low 1 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000027234   ⟹   ENSRNOP00000027234
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2192,124,289 - 192,144,609 (+)Ensembl
Rnor_6.0 Ensembl2207,108,552 - 207,128,554 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116493   ⟹   ENSRNOP00000092404
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2192,124,308 - 192,144,611 (+)Ensembl
RefSeq Acc Id: NM_012716   ⟹   NP_036848
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22192,124,309 - 192,143,826 (+)NCBI
Rnor_6.02207,108,552 - 207,128,561 (+)NCBI
Rnor_5.02226,529,294 - 226,549,303 (+)NCBI
RGSC_v3.42199,860,341 - 199,879,856 (+)RGD
Celera2184,591,461 - 184,610,976 (+)RGD
Sequence:
RefSeq Acc Id: XM_039101760   ⟹   XP_038957688
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22192,123,755 - 192,144,617 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036848   ⟸   NM_012716
- UniProtKB: P53987 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000027234   ⟸   ENSRNOT00000027234
RefSeq Acc Id: XP_038957688   ⟸   XM_039101760
- Peptide Label: isoform X1
- UniProtKB: P53987 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000092404   ⟸   ENSRNOT00000116493

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P53987-F1-model_v2 AlphaFold P53987 1-494 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691637
Promoter ID:EPDNEW_R2161
Type:single initiation site
Name:Slc16a1_1
Description:solute carrier family 16 member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02207,108,541 - 207,108,601EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3690 AgrOrtholog
BioCyc Gene G2FUF-51773 BioCyc
Ensembl Genes ENSRNOG00000019996 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000027234 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000092404.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027234 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000116493.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122399 IMAGE-MGC_LOAD
InterPro MCT UniProtKB/Swiss-Prot
  MCT1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_dom UniProtKB/Swiss-Prot
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25027 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93557 IMAGE-MGC_LOAD
NCBI Gene 25027 ENTREZGENE
PANTHER PTHR11360:SF24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc16a1 PhenoGen
PROSITE MFS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC229463
TIGRFAMs 2A0113 UniProtKB/Swiss-Prot
UniProt A0A8I6AI36_RAT UniProtKB/TrEMBL
  MOT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc16a1  solute carrier family 16 member 1  Slc16a1  solute carrier family 16 (monocarboxylate transporter), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-02 Slc16a1  solute carrier family 16 (monocarboxylate transporter), member 1  Slc16a1  solute carrier family 16, member 1 (monocarboxylic acid transporter 1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-19 Slc16a1  solute carrier family 16, member 1 (monocarboxylic acid transporter 1)  Slc16a1  solute carrier family 16 (monocarboxylic acid transporters), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc16a1  solute carrier family 16 (monocarboxylic acid transporters), member 1    solute carrier family 16, member 1  Name updated 1299863 APPROVED
2003-04-09 Slc16a1  solute carrier family 16, member 1    Solute carrier 16 (monocarboxylic acid transporter), member 1  Name updated 629478 APPROVED
2002-06-10 Slc16a1  Solute carrier 16 (monocarboxylic acid transporter), member 1      Symbol and Name status set to approved 70586 APPROVED