Abhd2 (abhydrolase domain containing 2, acylglycerol lipase) - Rat Genome Database

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Gene: Abhd2 (abhydrolase domain containing 2, acylglycerol lipase) Rattus norvegicus
Analyze
Symbol: Abhd2
Name: abhydrolase domain containing 2, acylglycerol lipase
RGD ID: 1311389
Description: Predicted to enable carboxylic ester hydrolase activity; hormone binding activity; and nuclear steroid receptor activity. Predicted to be involved in several processes, including medium-chain fatty acid metabolic process; response to steroid hormone; and sperm capacitation. Predicted to act upstream of or within negative regulation of smooth muscle cell migration and response to wounding. Predicted to be located in acrosomal vesicle. Predicted to be active in sperm flagellum and sperm plasma membrane. Orthologous to human ABHD2 (abhydrolase domain containing 2, acylglycerol lipase); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: abhydrolase domain containing 2; abhydrolase domain-containing protein 2; LOC293050; monoacylglycerol lipase ABHD2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21133,217,403 - 133,298,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,217,375 - 133,299,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,126,872 - 141,207,609 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01148,296,304 - 148,377,032 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01141,213,989 - 141,294,729 (+)NCBIRnor_WKY
Rnor_6.01140,998,240 - 141,087,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1140,998,240 - 141,087,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,965,576 - 142,049,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,025,144 - 135,111,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,103,531 - 135,191,046 (+)NCBI
Celera1125,281,300 - 125,361,782 (+)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
carbofuran  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
clomiphene  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diazinon  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
doxorubicin  (EXP)
elemental selenium  (ISO)
Enterolactone  (ISO)
estrone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (ISO)
hexestrol  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
inulin  (ISO)
isoprenaline  (EXP)
L-methionine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (EXP)
mestranol  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
picene  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
potassium chromate  (ISO)
raloxifene  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15721306   PMID:26989199   PMID:27247428  


Genomics

Comparative Map Data
Abhd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21133,217,403 - 133,298,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,217,375 - 133,299,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,126,872 - 141,207,609 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01148,296,304 - 148,377,032 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01141,213,989 - 141,294,729 (+)NCBIRnor_WKY
Rnor_6.01140,998,240 - 141,087,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1140,998,240 - 141,087,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,965,576 - 142,049,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,025,144 - 135,111,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,103,531 - 135,191,046 (+)NCBI
Celera1125,281,300 - 125,361,782 (+)NCBICelera
Cytogenetic Map1q31NCBI
ABHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,040,998 - 89,202,355 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1589,087,459 - 89,202,355 (+)EnsemblGRCh38hg38GRCh38
GRCh371589,631,687 - 89,745,586 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361587,432,429 - 87,546,591 (+)NCBINCBI36Build 36hg18NCBI36
Build 341587,432,627 - 87,541,199NCBI
Celera1566,032,695 - 66,146,881 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1565,743,212 - 65,857,546 (+)NCBIHuRef
CHM1_11589,472,357 - 89,586,578 (+)NCBICHM1_1
T2T-CHM13v2.01586,795,895 - 86,957,178 (+)NCBIT2T-CHM13v2.0
Abhd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39778,923,002 - 79,015,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl778,922,947 - 79,015,256 (+)EnsemblGRCm39 Ensembl
GRCm38779,273,266 - 79,361,601 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,273,199 - 79,365,508 (+)EnsemblGRCm38mm10GRCm38
MGSCv37786,418,152 - 86,506,487 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,146,779 - 79,235,114 (+)NCBIMGSCv36mm8
Celera776,673,721 - 76,758,716 (+)NCBICelera
Cytogenetic Map7D2NCBI
Abhd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,884,624 - 15,983,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,878,972 - 15,983,322 (-)NCBIChiLan1.0ChiLan1.0
ABHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,780,453 - 67,891,454 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11586,987,070 - 87,095,823 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1586,987,070 - 87,095,818 (+)Ensemblpanpan1.1panPan2
ABHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,151,500 - 52,255,024 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,151,535 - 52,249,612 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,787,785 - 54,891,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,570,316 - 52,673,869 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,570,371 - 52,673,867 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,092,905 - 52,196,309 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,303,690 - 52,406,947 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,642,383 - 52,745,916 (+)NCBIUU_Cfam_GSD_1.0
Abhd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640131,254,659 - 131,360,435 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648314,974,035 - 15,074,154 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648314,974,053 - 15,079,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl754,655,804 - 54,770,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1754,655,694 - 54,776,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2759,630,969 - 59,746,589 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,631,436 - 7,742,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,631,412 - 7,740,394 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605939,085,426 - 39,196,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476816,297,464 - 16,402,624 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476816,283,369 - 16,404,476 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abhd2
461 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:313
Count of miRNA genes:180
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000023506
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat
61346Rf2Renal disease susceptibility QTL 23.7urine protein amount (VT:0005160)urine protein level (CMO:0000591)199267916144267916Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)199267916144267916Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
2303591Gluco41Glucose level QTL 412blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1102168504147168504Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1102268556147268556Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1102813953151162766Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1103111621148111621Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847151047847Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
631570Bp94Blood pressure QTL 940.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123479780142990467Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1131763437159756369Rat

Markers in Region
BF413329  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,215,894 - 133,215,984 (+)MAPPERmRatBN7.2
Rnor_6.01140,996,732 - 140,996,821NCBIRnor6.0
Rnor_5.01141,964,068 - 141,964,157UniSTSRnor5.0
RGSC_v3.41135,023,636 - 135,023,725UniSTSRGSC3.4
Celera1125,279,792 - 125,279,881UniSTS
RH 3.4 Map11058.8UniSTS
Cytogenetic Map1q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 25 53 37 19 37 1 1 74 35 41 11 1
Low 1 18 4 4 4 7 10 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000023506   ⟹   ENSRNOP00000023506
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,217,439 - 133,299,061 (+)Ensembl
Rnor_6.0 Ensembl1140,998,240 - 141,087,405 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090897   ⟹   ENSRNOP00000072489
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,217,375 - 133,299,061 (+)Ensembl
Rnor_6.0 Ensembl1140,998,260 - 141,087,084 (+)Ensembl
RefSeq Acc Id: NM_001106275   ⟹   NP_001099745
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21133,217,403 - 133,298,564 (+)NCBI
Rnor_6.01140,998,240 - 141,087,405 (+)NCBI
Rnor_5.01141,965,576 - 142,049,687 (+)NCBI
RGSC_v3.41135,025,144 - 135,111,792 (+)RGD
Celera1125,281,300 - 125,361,782 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099745 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM08574 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001099745   ⟸   NM_001106275
- UniProtKB: D4A7W1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000023506   ⟸   ENSRNOT00000023506
RefSeq Acc Id: ENSRNOP00000072489   ⟸   ENSRNOT00000090897
Protein Domains
AB hydrolase-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K337-F1-model_v2 AlphaFold A0A0G2K337 1-453 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690129
Promoter ID:EPDNEW_R652
Type:initiation region
Name:Abhd2_1
Description:abhydrolase domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01140,998,274 - 140,998,334EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311389 AgrOrtholog
BioCyc Gene G2FUF-58810 BioCyc
BioCyc Pathway LIPAS-PWY [triacylglycerol degradation] BioCyc
  PWY-7420 [monoacylglycerol metabolism (yeast)] BioCyc
Ensembl Genes ENSRNOG00000017120 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000023506 ENTREZGENE
  ENSRNOP00000023506.4 UniProtKB/TrEMBL
  ENSRNOP00000072489.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023506 ENTREZGENE
  ENSRNOT00000023506.7 UniProtKB/TrEMBL
  ENSRNOT00000090897.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB-Hydro_YheT UniProtKB/TrEMBL
  AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  UPF0017_hydro-like_CS UniProtKB/TrEMBL
KEGG Report rno:293050 UniProtKB/TrEMBL
NCBI Gene 293050 ENTREZGENE
PANTHER ABHYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MONOACYLGLYCEROL LIPASE ABHD2 UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PharmGKB ABHD2 RGD
PhenoGen Abhd2 PhenoGen
PIRSF Ab_hydro_YheT UniProtKB/TrEMBL
PROSITE UPF0017 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A0G2K337_RAT UniProtKB/TrEMBL
  D4A7W1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-13 Abhd2  abhydrolase domain containing 2, acylglycerol lipase  Abhd2  abhydrolase domain containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Abhd2  abhydrolase domain containing 2   Abhd2_predicted  abhydrolase domain containing 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Abhd2_predicted  abhydrolase domain containing 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED