Gene: Tfpi2 (tissue factor pathway inhibitor 2) Rattus norvegicus
Analyze
Symbol:
Tfpi2
Name:
tissue factor pathway inhibitor 2
RGD ID:
628629
Description:
Predicted to have serine-type endopeptidase inhibitor activity. Involved in cellular response to fluid shear stress. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2); INTERACTS WITH (S)-colchicine; 1-naphthyl isothiocyanate; acrylamide.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TFPI2 (tissue factor pathway inhibitor 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Tfpi2 (tissue factor pathway inhibitor 2) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Tfpi2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TFPI2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TFPI2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Tfpi2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TFPI2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
TFPI2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Tfpi2 (tissue factor pathway inhibitor 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
TFPI2 (tissue factor pathway inhibitor 2)
Alliance
DIOPT (HGNC|PhylomeDB|TreeFam)
Mus musculus (house mouse):
Tfpi2 (tissue factor pathway inhibitor 2)
Alliance
DIOPT (PhylomeDB|TreeFam)
Danio rerio (zebrafish):
tfpi2 (tissue factor pathway inhibitor 2)
Alliance
DIOPT (PhylomeDB|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 4 28,947,951 - 28,953,261 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 4 28,947,965 - 28,953,067 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 4 28,855,875 - 28,860,297 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 4 28,807,080 - 28,811,502 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 4 28,825,427 - 28,829,850 (-) NCBI Celera 4 27,368,594 - 27,373,001 (-) NCBI Celera Cytogenetic Map 4 q13 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
pleomorphic xanthoastrocytoma ISO RGD:736798 8554872 ClinVar Annotator: match by term: Pleomorphic xanthoastrocytoma ClinVar PMID:28299358
Imported Annotations - CTD
Breast Neoplasms ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16298037 Colorectal Neoplasms ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19435926 Experimental Liver Cirrhosis ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25380136 hepatocellular carcinoma ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17464989 , PMID:28284560 melanoma ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17372906 Neoplasm Metastasis ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17372906 osteoarthritis ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15292528 pancreatic cancer ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16965396 rheumatoid arthritis ISO RGD:736798 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15292528 , PMID:17379860
(S)-colchicine increases expression EXP 6480464 Colchicine results in increased expression of TFPI2 mRNA CTD PMID:20624997 (S)-nicotine decreases expression ISO RGD:736798 6480464 Nicotine results in decreased expression of TFPI2 mRNA CTD PMID:12588870 (S)-nicotine increases expression ISO RGD:736798 6480464 Nicotine results in increased expression of TFPI2 mRNA CTD PMID:12588870 (S)-nicotine multiple interactions ISO RGD:736798 6480464 alpha-cobratoxin inhibits the reaction [Nicotine results in decreased expression of TFPI2 mRNA], Mecamylamine inhibits the reaction [Nicotine results in decreased expression of TFPI2 mRNA] CTD PMID:12588870 1,1-dichloroethene decreases expression ISO RGD:736799 6480464 vinylidene chloride results in decreased expression of TFPI2 mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression ISO RGD:736799 6480464 1, 2-Dimethylhydrazine results in decreased expression of TFPI2 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of TFPI2 mRNA CTD PMID:25380136 17beta-estradiol increases expression ISO RGD:736798 6480464 Estradiol results in increased expression of TFPI2 mRNA CTD PMID:16202921 , PMID:19619570 17beta-estradiol multiple interactions ISO RGD:736798 6480464 [Estradiol co-treated with Progesterone] results in increased expression of TFPI2 mRNA, [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of TFPI2 mRNA CTD PMID:19619570 , PMID:20660070 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO RGD:736798 6480464 2 more ... CTD PMID:23146750 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:736798 6480464 2 more ... CTD PMID:23146750 , PMID:31173147 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:736798 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of TFPI2 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:736798 6480464 Tetrachlorodibenzodioxin results in decreased expression of TFPI2 mRNA CTD PMID:19619570 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:736798 6480464 3 more ... CTD PMID:29947894 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736798 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of TFPI2 mRNA more ... CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions ISO RGD:736798 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of TFPI2 mRNA CTD PMID:28628672 4-hydroxyphenyl retinamide increases expression ISO RGD:736799 6480464 Fenretinide results in increased expression of TFPI2 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine decreases methylation ISO RGD:736798 6480464 Decitabine results in decreased methylation of TFPI2 promoter CTD PMID:19435926 5-aza-2'-deoxycytidine multiple interactions ISO RGD:736798 6480464 [[Decitabine co-treated with trichostatin A] affects the methylation of TFPI2 promoter] which affects the expression of TFPI2 mRNA, [Decitabine co-treated with trichostatin A] affects the methylation of TFPI2 promoter CTD PMID:17464989 5-aza-2'-deoxycytidine increases expression ISO RGD:736798 6480464 Decitabine results in increased expression of TFPI2 mRNA CTD PMID:19435926 8-Br-cAMP increases expression ISO RGD:736798 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TFPI2 mRNA CTD PMID:20147733 , PMID:22079614 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of TFPI2 mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO RGD:736798 6480464 Aflatoxin B1 affects the expression of TFPI2 protein CTD PMID:20106945 all-trans-retinoic acid decreases expression ISO RGD:736798 6480464 Tretinoin results in decreased expression of TFPI2 mRNA CTD PMID:23724009 all-trans-retinoic acid increases expression ISO RGD:736798 6480464 Tretinoin results in increased expression of TFPI2 mRNA CTD PMID:21934132 , PMID:23830798 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TFPI2 mRNA CTD PMID:16483693 amphibole asbestos increases expression ISO RGD:736798 6480464 Asbestos, Amphibole results in increased expression of TFPI2 mRNA CTD PMID:20831825 amphibole asbestos increases expression EXP 6480464 Asbestos, Amphibole results in increased expression of TFPI2 mRNA CTD PMID:22352330 arsenite(3-) decreases expression ISO RGD:736798 6480464 arsenite results in decreased expression of TFPI2 mRNA CTD PMID:23974009 avobenzone increases expression ISO RGD:736798 6480464 avobenzone results in increased expression of TFPI2 mRNA CTD PMID:31016361 benzo[a]pyrene increases expression ISO RGD:736798 6480464 Benzo(a)pyrene results in increased expression of TFPI2 mRNA CTD PMID:17879257 more ... benzo[a]pyrene decreases methylation ISO RGD:736798 6480464 Benzo(a)pyrene results in decreased methylation of TFPI2 promoter CTD PMID:27901495 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:736799 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of TFPI2 mRNA] CTD PMID:19850644 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:736799 6480464 Diethylhexyl Phthalate results in decreased expression of TFPI2 mRNA CTD PMID:28085963 bis(2-ethylhexyl) phthalate increases expression ISO RGD:736799 6480464 Diethylhexyl Phthalate results in increased expression of TFPI2 mRNA CTD PMID:19850644 bisphenol A increases expression ISO RGD:736798 6480464 bisphenol A results in increased expression of TFPI2 mRNA CTD PMID:19371625 , PMID:31715268 bisphenol A increases methylation ISO RGD:736798 6480464 bisphenol A results in increased methylation of TFPI2 gene CTD PMID:28582417 bisphenol A multiple interactions ISO RGD:736798 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TFPI2 mRNA CTD PMID:28628672 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TFPI2 mRNA CTD PMID:25181051 bisphenol F multiple interactions ISO RGD:736798 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TFPI2 mRNA CTD PMID:28628672 carbamazepine affects expression ISO RGD:736798 6480464 Carbamazepine affects the expression of TFPI2 mRNA CTD PMID:25979313 carbon nanotube decreases expression ISO RGD:736799 6480464 Nanotubes, Carbon analog results in decreased expression of TFPI2 mRNA CTD PMID:25620056 carbon nanotube increases expression ISO RGD:736799 6480464 Nanotubes, Carbon analog results in increased expression of TFPI2 mRNA, Nanotubes, Carbon results in increased expression of TFPI2 mRNA CTD PMID:25554681 , PMID:25620056 carmustine affects response to substance ISO RGD:736798 6480464 TFPI2 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 chloroprene decreases expression ISO RGD:736799 6480464 Chloroprene results in decreased expression of TFPI2 mRNA CTD PMID:23125180 cisplatin multiple interactions ISO RGD:736798 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of TFPI2 mRNA, [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of TFPI2 mRNA CTD PMID:27392435 , PMID:30871063 cisplatin decreases expression ISO RGD:736798 6480464 Cisplatin results in decreased expression of TFPI2 mRNA CTD PMID:27392435 clofibrate increases expression ISO RGD:736799 6480464 Clofibrate results in increased expression of TFPI2 mRNA CTD PMID:17585979 clofibrate multiple interactions ISO RGD:736799 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of TFPI2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TFPI2 mRNA] CTD PMID:17585979 cobalt dichloride decreases expression ISO RGD:736798 6480464 cobaltous chloride results in decreased expression of TFPI2 mRNA CTD PMID:19320972 , PMID:19376846 copper atom decreases expression ISO RGD:736798 6480464 Copper results in decreased expression of TFPI2 mRNA CTD PMID:19747488 copper(0) decreases expression ISO RGD:736798 6480464 Copper results in decreased expression of TFPI2 mRNA CTD PMID:19747488 copper(II) sulfate affects expression ISO RGD:736798 6480464 Copper Sulfate affects the expression of TFPI2 mRNA CTD PMID:19549813 crocidolite asbestos affects expression ISO RGD:736798 6480464 Asbestos, Crocidolite affects the expression of TFPI2 mRNA CTD PMID:25757056 crocidolite asbestos multiple interactions ISO RGD:736798 6480464 IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein], NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein] CTD PMID:28056339 crocidolite asbestos multiple interactions ISO RGD:736799 6480464 [CASP1 protein affects the susceptibility to Asbestos, Crocidolite] which affects the expression of TFPI2 protein CTD PMID:28056339 crocidolite asbestos increases secretion ISO RGD:736798 6480464 Asbestos, Crocidolite results in increased secretion of TFPI2 protein CTD PMID:28056339 crocidolite asbestos increases expression ISO RGD:736798 6480464 Asbestos, Crocidolite results in increased expression of TFPI2 mRNA CTD PMID:18687144 more ... cyclosporin A increases expression ISO RGD:736798 6480464 Cyclosporine results in increased expression of TFPI2 mRNA CTD PMID:20106945 dexamethasone decreases expression ISO RGD:736798 6480464 Dexamethasone results in decreased expression of TFPI2 mRNA CTD PMID:25047013 dexamethasone multiple interactions ISO RGD:736798 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of TFPI2 mRNA more ... CTD PMID:28628672 dibenzo[a,l]pyrene increases expression ISO RGD:736798 6480464 dibenzo(a, l)pyrene results in increased expression of TFPI2 mRNA CTD PMID:15735009 dioxygen multiple interactions ISO RGD:736799 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TFPI2 mRNA CTD PMID:30529165 dorsomorphin multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin affects response to substance ISO RGD:736798 6480464 TFPI2 protein affects the susceptibility to Doxorubicin CTD PMID:16217747 doxorubicin decreases expression ISO RGD:736798 6480464 Doxorubicin results in decreased expression of TFPI2 mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:736798 6480464 Doxorubicin results in increased expression of TFPI2 mRNA CTD PMID:30031762 endosulfan increases expression ISO RGD:736798 6480464 Endosulfan results in increased expression of TFPI2 mRNA CTD PMID:26615145 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of TFPI2 mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:736798 6480464 entinostat results in increased expression of TFPI2 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI2 mRNA CTD PMID:27188386 etoposide affects response to substance ISO RGD:736798 6480464 TFPI2 protein affects the susceptibility to Etoposide CTD PMID:16217747 fonofos increases methylation ISO RGD:736798 6480464 Fonofos results in increased methylation of TFPI2 promoter CTD PMID:22847954 furan increases expression EXP 6480464 furan results in increased expression of TFPI2 mRNA CTD PMID:27387713 gold atom increases expression ISO RGD:736798 6480464 Gold results in increased expression of TFPI2 mRNA CTD PMID:29705079 gold(0) increases expression ISO RGD:736798 6480464 Gold results in increased expression of TFPI2 mRNA CTD PMID:29705079 indometacin multiple interactions ISO RGD:736798 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of TFPI2 mRNA more ... CTD PMID:28628672 lucanthone increases expression ISO RGD:736798 6480464 Lucanthone results in increased expression of TFPI2 mRNA CTD PMID:21148553 lycopene decreases expression ISO RGD:736798 6480464 lycopene results in decreased expression of TFPI2 mRNA CTD PMID:16886892 Mecamylamine multiple interactions ISO RGD:736798 6480464 Mecamylamine inhibits the reaction [Nicotine results in decreased expression of TFPI2 mRNA] CTD PMID:12588870 medroxyprogesterone acetate decreases expression ISO RGD:736798 6480464 Medroxyprogesterone Acetate results in decreased expression of TFPI2 mRNA CTD PMID:20843944 melphalan increases expression ISO RGD:736798 6480464 Melphalan results in increased expression of TFPI2 mRNA CTD PMID:22363485 mercury dibromide multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI2 mRNA CTD PMID:27188386 methotrexate affects expression ISO RGD:736799 6480464 Methotrexate affects the expression of TFPI2 mRNA CTD PMID:18502557 methylisothiazolinone increases expression ISO RGD:736798 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of TFPI2 mRNA CTD PMID:31629900 methylmercury chloride increases expression ISO RGD:736798 6480464 methylmercuric chloride results in increased expression of TFPI2 mRNA CTD PMID:28001369 mitomycin C affects response to substance ISO RGD:736798 6480464 TFPI2 protein affects the susceptibility to Mitomycin CTD PMID:16217747 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of TFPI2 mRNA CTD PMID:25380136 nickel sulfate increases expression ISO RGD:736798 6480464 nickel sulfate results in increased expression of TFPI2 mRNA CTD PMID:22714537 nicotine multiple interactions ISO RGD:736798 6480464 alpha-cobratoxin inhibits the reaction [Nicotine results in decreased expression of TFPI2 mRNA], Mecamylamine inhibits the reaction [Nicotine results in decreased expression of TFPI2 mRNA] CTD PMID:12588870 nicotine increases expression ISO RGD:736798 6480464 Nicotine results in increased expression of TFPI2 mRNA CTD PMID:12588870 nicotine decreases expression ISO RGD:736798 6480464 Nicotine results in decreased expression of TFPI2 mRNA CTD PMID:12588870 O-methyleugenol increases expression ISO RGD:736798 6480464 methyleugenol results in increased expression of TFPI2 mRNA CTD PMID:32234424 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of TFPI2 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TFPI2 mRNA CTD PMID:25729387 ozone decreases expression ISO RGD:736799 6480464 Ozone results in decreased expression of TFPI2 mRNA, Ozone results in decreased expression of TFPI2 protein CTD PMID:16183385 ozone increases expression EXP 6480464 Ozone results in increased expression of TFPI2 mRNA CTD PMID:26667333 ozone multiple interactions ISO RGD:736799 6480464 [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of TFPI2 mRNA, [NOTCH4 gene mutant form affects the susceptibility to Ozone] which affects the expression of TFPI2 mRNA CTD PMID:25658374 paclitaxel affects response to substance ISO RGD:736798 6480464 TFPI2 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 panobinostat multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI2 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:736798 6480464 panobinostat results in increased expression of TFPI2 mRNA CTD PMID:26272509 paracetamol multiple interactions ISO RGD:736799 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of TFPI2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TFPI2 mRNA] CTD PMID:17585979 paracetamol increases expression ISO RGD:736798 6480464 Acetaminophen results in increased expression of TFPI2 mRNA CTD PMID:21420995 , PMID:29067470 paracetamol decreases expression ISO RGD:736799 6480464 Acetaminophen results in decreased expression of TFPI2 mRNA CTD PMID:11264010 paracetamol affects expression ISO RGD:736799 6480464 Acetaminophen affects the expression of TFPI2 mRNA CTD PMID:17562736 parathion increases methylation ISO RGD:736798 6480464 Parathion results in increased methylation of TFPI2 promoter CTD PMID:22847954 phenobarbital affects expression ISO RGD:736799 6480464 Phenobarbital affects the expression of TFPI2 mRNA CTD PMID:19136022 phenobarbital affects expression ISO RGD:736798 6480464 Phenobarbital affects the expression of TFPI2 mRNA CTD PMID:19159669 phenylmercury acetate increases expression ISO RGD:736798 6480464 Phenylmercuric Acetate results in increased expression of TFPI2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI2 mRNA CTD PMID:27188386 pirinixic acid affects expression ISO RGD:736799 6480464 pirinixic acid affects the expression of TFPI2 mRNA CTD PMID:19136022 pirinixic acid increases expression ISO RGD:736799 6480464 pirinixic acid results in increased expression of TFPI2 mRNA CTD PMID:17426115 more ... pirinixic acid multiple interactions ISO RGD:736799 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of TFPI2 mRNA] CTD PMID:20059764 pirinixic acid decreases expression ISO RGD:736799 6480464 pirinixic acid results in decreased expression of TFPI2 mRNA CTD PMID:18445702 prednisolone decreases expression ISO RGD:736798 6480464 Prednisolone results in decreased expression of TFPI2 mRNA CTD PMID:17379860 progesterone multiple interactions ISO RGD:736798 6480464 [Estradiol co-treated with Progesterone] results in increased expression of TFPI2 mRNA CTD PMID:20660070 progesterone increases expression ISO RGD:736798 6480464 Progesterone results in increased expression of TFPI2 mRNA CTD PMID:21795739 quercetin affects expression EXP 6480464 Quercetin affects the expression of TFPI2 mRNA CTD PMID:18178720 quercetin increases expression ISO RGD:736798 6480464 Quercetin results in increased expression of TFPI2 mRNA CTD PMID:21632981 resveratrol increases expression ISO RGD:736798 6480464 resveratrol results in increased expression of TFPI2 mRNA CTD PMID:19371625 , PMID:25888808 SB 431542 multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Securinine increases expression ISO RGD:736798 6480464 securinine results in increased expression of TFPI2 mRNA CTD PMID:32662633 serpentine asbestos increases expression ISO RGD:736798 6480464 Asbestos, Serpentine results in increased expression of TFPI2 mRNA CTD PMID:24160326 silicon dioxide increases expression ISO RGD:736798 6480464 Silicon Dioxide analog results in increased expression of TFPI2 mRNA, Silicon Dioxide results in increased expression of TFPI2 mRNA CTD PMID:25351596 , PMID:25895662 sodium arsenite increases expression ISO RGD:736798 6480464 sodium arsenite results in increased expression of TFPI2 mRNA CTD PMID:22714537 sodium arsenite increases expression ISO RGD:736799 6480464 sodium arsenite results in increased expression of TFPI2 mRNA CTD PMID:16014739 sodium dodecyl sulfate increases expression ISO RGD:736798 6480464 Sodium Dodecyl Sulfate results in increased expression of TFPI2 mRNA CTD PMID:31734321 sunitinib decreases expression ISO RGD:736798 6480464 Sunitinib results in decreased expression of TFPI2 mRNA CTD PMID:31533062 temozolomide affects response to substance ISO RGD:736798 6480464 TFPI2 mRNA affects the susceptibility to temozolomide CTD PMID:16365179 terbufos increases methylation ISO RGD:736798 6480464 terbufos results in increased methylation of TFPI2 promoter CTD PMID:22847954 tert-butyl hydroperoxide increases expression ISO RGD:736798 6480464 tert-Butylhydroperoxide results in increased expression of TFPI2 mRNA CTD PMID:15336504 Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of TFPI2 mRNA CTD PMID:21515302 tetrachloromethane affects expression ISO RGD:736799 6480464 Carbon Tetrachloride affects the expression of TFPI2 mRNA CTD PMID:17484886 tetrachloromethane decreases expression ISO RGD:736799 6480464 Carbon Tetrachloride results in decreased expression of TFPI2 mRNA CTD PMID:27339419 , PMID:31919559 tetraphene decreases expression ISO RGD:736799 6480464 benz(a)anthracene results in decreased expression of TFPI2 mRNA CTD PMID:26377693 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TFPI2 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of TFPI2 mRNA CTD PMID:25729387 topotecan affects response to substance ISO RGD:736798 6480464 TFPI2 protein affects the susceptibility to Topotecan CTD PMID:16217747 trichostatin A multiple interactions ISO RGD:736798 6480464 [[decitabine co-treated with trichostatin A] affects the methylation of TFPI2 promoter] which affects the expression of TFPI2 mRNA, [decitabine co-treated with trichostatin A] affects the methylation of TFPI2 promoter CTD PMID:17464989 trichostatin A increases expression ISO RGD:736798 6480464 trichostatin A results in increased expression of TFPI2 mRNA CTD PMID:24935251 , PMID:26272509 triclosan decreases expression ISO RGD:736798 6480464 Triclosan results in decreased expression of TFPI2 mRNA CTD PMID:30510588 urethane increases expression ISO RGD:736798 6480464 Urethane results in increased expression of TFPI2 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:736799 6480464 Valproic Acid affects the expression of TFPI2 mRNA CTD PMID:17292431 valproic acid multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI2 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:736798 6480464 Valproic Acid results in increased expression of TFPI2 mRNA CTD PMID:23179753 more ... vincaleukoblastine affects response to substance ISO RGD:736798 6480464 TFPI2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 vincaleukoblastine increases expression EXP 6480464 Vinblastine results in increased expression of TFPI2 mRNA CTD PMID:20624997 vorinostat increases expression ISO RGD:736798 6480464 vorinostat results in increased expression of TFPI2 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:736798 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI2 mRNA CTD PMID:27188386 zinc atom increases expression ISO RGD:736798 6480464 Zinc results in increased expression of TFPI2 mRNA CTD PMID:16870260 zinc dichloride increases expression ISO RGD:736798 6480464 zinc chloride results in increased expression of TFPI2 mRNA CTD PMID:16870260 zinc(0) increases expression ISO RGD:736798 6480464 Zinc results in increased expression of TFPI2 mRNA CTD PMID:16870260 zoledronic acid increases expression ISO RGD:736798 6480464 zoledronic acid results in increased expression of TFPI2 mRNA CTD PMID:24714768
Gene-Chemical Interaction Annotations
