Tfpi2 (tissue factor pathway inhibitor 2)

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Gene: Tfpi2 (tissue factor pathway inhibitor 2) Rattus norvegicus

Analyze

Symbol:

Tfpi2

Name:

tissue factor pathway inhibitor 2

RGD ID:

628629

Description:

Predicted to have serine-type endopeptidase inhibitor activity. Involved in cellular response to fluid shear stress. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2); INTERACTS WITH (S)-colchicine; 1-naphthyl isothiocyanate; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	4	28,947,951 - 28,953,261 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	28,947,965 - 28,953,067 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	28,855,875 - 28,860,297 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	28,807,080 - 28,811,502 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	28,825,427 - 28,829,850 (-)	NCBI
Celera	4	27,368,594 - 27,373,001 (-)	NCBI		Celera
Cytogenetic Map	4	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

Breast Neoplasms (ISO)

Carotid Artery Injuries (IEP)

Colorectal Neoplasms (ISO)

Experimental Liver Cirrhosis (ISO)

hepatocellular carcinoma (ISO)

melanoma (ISO)

Neoplasm Invasiveness (ISO)

Neoplasm Metastasis (ISO)

osteoarthritis (ISO)

pancreatic cancer (ISO)

pleomorphic xanthoastrocytoma (ISO)

retinal degeneration (ISO)

rheumatoid arthritis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-colchicine (EXP)

(S)-nicotine (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

8-Br-cAMP (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amphibole asbestos (EXP,ISO)

arsenite(3-) (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

carmustine (ISO)

chloroprene (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dibenzo[a,l]pyrene (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP,ISO)

entinostat (ISO)

etoposide (ISO)

fonofos (ISO)

furan (EXP)

gold atom (ISO)

gold(0) (ISO)

indometacin (ISO)

lucanthone (ISO)

lycopene (ISO)

Mecamylamine (ISO)

medroxyprogesterone acetate (ISO)

melphalan (ISO)

mercury dibromide (ISO)

methotrexate (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

mitomycin C (ISO)

N-nitrosodimethylamine (EXP)

nickel sulfate (ISO)

nicotine (ISO)

O-methyleugenol (ISO)

oxaliplatin (EXP)

ozone (EXP,ISO)

paclitaxel (ISO)

panobinostat (ISO)

paracetamol (ISO)

parathion (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

prednisolone (ISO)

progesterone (ISO)

quercetin (EXP,ISO)

resveratrol (ISO)

SB 431542 (ISO)

Securinine (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

sunitinib (ISO)

temozolomide (ISO)

terbufos (ISO)

tert-butyl hydroperoxide (ISO)

Tesaglitazar (EXP)

tetrachloromethane (ISO)

tetraphene (ISO)

topotecan (EXP,ISO)

trichostatin A (ISO)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

vincaleukoblastine (EXP,ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc dichloride (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood coagulation (IEA)

cellular response to fluid shear stress (IEP)

negative regulation of endopeptidase activity (IEA)

Cellular Component

extracellular space (IBA)

Molecular Function

serine-type endopeptidase inhibitor activity (IBA)

References

References - curated


1.	Ekstrand J, etal., J Vasc Surg. 2010 Jul;52(1):167-75. doi: 10.1016/j.jvs.2010.02.282.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	Hisaka T, etal., Thromb Haemost 2002 Aug;88(2):356-7.
5.	Jian P, etal., J Pediatr Hematol Oncol. 2012 Jan;34(1):43-6. doi: 10.1097/MPH.0b013e3182277276.
6.	Konduri SD, etal., Oncogene. 2001 Oct 18;20(47):6938-45.
7.	MGD data from the GO Consortium
8.	Miyagi Y, etal., DNA Cell Biol 1996 Nov;15(11):947-54.
9.	Obata R, etal., Eye (Lond). 2005 Apr;19(4):464-8.
10.	RGD automated data pipeline
11.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23979707

Genomics

Comparative Map Data

Tfpi2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	4	28,947,951 - 28,953,261 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	28,947,965 - 28,953,067 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	28,855,875 - 28,860,297 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	28,807,080 - 28,811,502 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	28,825,427 - 28,829,850 (-)	NCBI
Celera	4	27,368,594 - 27,373,001 (-)	NCBI		Celera
Cytogenetic Map	4	q13	NCBI

TFPI2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	93,885,396 - 93,890,753 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	93,885,396 - 93,890,753 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	93,514,709 - 93,520,303 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	93,353,678 - 93,358,001 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	93,160,395 - 93,164,716	NCBI
Celera	7	88,214,047 - 88,218,363 (-)	NCBI
Cytogenetic Map	7	q21.3	NCBI
HuRef	7	88,122,436 - 88,128,017 (-)	NCBI		HuRef
CHM1_1	7	93,444,941 - 93,450,535 (-)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	92,843,873 - 92,849,467 (-)	NCBI

Tfpi2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	3,962,589 - 3,988,977 (-)	NCBI	GRCm39		mm39
GRCm38	6	3,962,589 - 3,988,978 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	3,962,595 - 3,988,919 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	3,912,595 - 3,918,354 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	3,912,595 - 3,918,356 (-)	NCBI			mm8
Celera	6	4,109,201 - 4,114,968 (-)	NCBI		Celera
Cytogenetic Map	6	A1	NCBI
cM Map	6	1.81	NCBI

Tfpi2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	10,631,843 - 10,641,538 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955432	10,635,626 - 10,641,345 (-)	NCBI	ChiLan1.0	ChiLan1.0

TFPI2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	99,425,901 - 99,431,099 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	99,426,006 - 99,431,099 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	85,835,141 - 85,839,515 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

TFPI2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	14	19,399,720 - 19,403,708 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	14	19,399,259 - 19,403,890 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Tfpi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936803	69,296 - 90,270 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TFPI2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	73,673,535 - 73,689,095 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	73,684,236 - 73,694,663 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	80,646,484 - 80,656,913 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TFPI2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	55,134,921 - 55,139,862 (+)	NCBI
ChlSab1.1 Ensembl	21	55,135,198 - 55,140,801 (+)	Ensembl

Tfpi2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624813	571,592 - 577,268 (-)	NCBI

Position Markers

RH130733

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	28,948,080 - 28,948,288	NCBI	Rnor6.0
Rnor_5.0	4	28,855,612 - 28,855,820	UniSTS	Rnor5.0
RGSC_v3.4	4	28,806,817 - 28,807,025	UniSTS	RGSC3.4
Celera	4	27,368,331 - 27,368,539	UniSTS
Cytogenetic Map	4	q13	UniSTS
RH 3.4 Map	4	434.12	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357343	Gluco4	Glucose level QTL 4		0.00002	adipocyte glucose uptake trait (VT:0004185)	adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)	4	1	29778604	Rat
1357341	Gluco5	Glucose level QTL 5	6.4		adipocyte free fatty acid secretion trait (VT:0010465)	absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)	4	1	29778604	Rat
738021	Hcar13	Hepatocarcinoma resistance QTL 13	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	4	1	31554484	Rat
634323	Hc2	Hypercalciuria QTL 2	2.15		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	4	1	42118977	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	3043231	79575658	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	3043231	145254791	Rat
2302371	Stl22	Serum triglyceride level QTL 22	5.15		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	3044017	55791834	Rat
1358203	Stl19	Serum triglyceride level QTL 19	2.8	0.002	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	3044017	64915903	Rat
631642	Stl2	Serum triglyceride level QTL 2	3.3		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	3047807	55324857	Rat
631209	Bw2	Body weight QTL2	4.2		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	6467693	43414792	Rat
1300141	Bp178	Blood pressure QTL 178			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	6572939	37703537	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	7342404	92484039	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	7850904	182171018	Rat
9590304	Scort17	Serum corticosterone level QTL 17	4.96	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	8052189	53052189	Rat
6478724	Anxrr35	Anxiety related response QTL 35		0.00449	defecation behavior trait (VT:0010462)	defecation measurement (CMO:0000997)	4	8052189	53052189	Rat
6478766	Anxrr47	Anxiety related response QTL 47		0.09637	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	8052189	53052189	Rat
6478769	Anxrr48	Anxiety related response QTL 48		0.02514	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	8052189	53052189	Rat
8552906	Pigfal3	Plasma insulin-like growth factor 1 level QTL 3			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	8052189	53052189	Rat
8694374	Bw155	Body weight QTL 155	3.39	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	4	8052189	53052189	Rat
2303585	Bw86	Body weight QTL 86	4		body mass (VT:0001259)	body weight (CMO:0000012)	4	12638974	57638974	Rat
7387227	Uae40	Urinary albumin excretion QTL 40	2.9	0.0052	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	16149941	61149941	Rat
70222	Eae2	Experimental allergic encephalomyelitis QTL 2	4.3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	4	18222187	37685319	Rat
1354665	Stl10	Serum triglyceride level QTL 10	3.57		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	18222187	43414792	Rat
61412	Pia2	Pristane induced arthritis QTL 2	3.9		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	4	18222187	61039065	Rat
8552803	Bw144	Body weight QTL 144	16		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	19618866	31825560	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	23850384	169318094	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	23991721	76238799	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	23991721	76238799	Rat
1578655	Bmd11	Bone mineral density QTL 11	11		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	4	24631874	69631874	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	26654749	81874227	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	221
Count of miRNA genes:	158
Interacting mature miRNAs:	175
Transcripts:	ENSRNOT00000013989
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	1	43	53	38	18	38	7	8	60	31	34	11	7
Below cutoff	2		4	3	1	3	1	3	14	4	6		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_173141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAHX01028280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC096039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ428954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000013989 ⟹ ENSRNOP00000013989

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	28,947,965 - 28,953,067 (-)	Ensembl

RefSeq Acc Id:

NM_173141 ⟹ NP_775164

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	28,948,343 - 28,952,765 (-)	NCBI
Rnor_5.0	4	28,855,875 - 28,860,297 (-)	NCBI
RGSC_v3.4	4	28,807,080 - 28,811,502 (-)	RGD
Celera	4	27,368,594 - 27,373,001 (-)	RGD

Sequence:

show sequence

AGCACTCTCCTCCCTCTCTCCGCGCATCCAGGCAGCCGCACCACCCGGTCATATGGACCCTGCT
ACATCCCTGAGACTGTGGAATCTGCCGCTGCTCCTGGTGGGTTCAGCTCTTGGTCTCGCTTCAG
TATCTGCCCAAGGGAATAACTTAGAGATCTGCCTCTTGCCTTTGGACATGGGACCTTGTAAGGC
CCTCATCCCCAAGTTCTACTATGACAGGGACCAGAAGAAATGCCGCAGATTCAAGTATGGAGGC
TGCCTGGGCAATGCCAACAATTTCCACAGTCGGAAACTCTGCGAACACACTTGCGGAAATAAGG
AGAAAGTTCCTTGGGTCTGTCGATCAGCAGTCAGAACGTATCCGTGTGATAAACCCAATACAGA
GTTTTTCTTCAATCTGAAAACTATGACATGTGAGCCTCTTAGGCCTGGTCTGTGTAGCAGGACT
ACGAATGTGTTCCCCGAGGAAGCTATGTGTAAGAGCTTATGTGAACCAAGGAAAAGTATCCCAT
CATTTTGCTCCAGTCCAAAAGATGAAGGCCTGTGTTCTGCTAATGTGACCCGCTATTATTTTAA
TTCAAGAAACAAAACCTGCGAGACCTTCACCTACACTGGCTGTGGTGGCAATGAAAATAACTTT
TATTACCTGGATGCTTGCAACCGTGCCTGTGTTAAAGCCTTGAAGAAGCCCAAGAGAAGGAAGA
TAGGTGATTTCCTGCCGAGATTTTGGAAGCTTCGTTCTTAAGCATTTTCTCATACTCAAGGAAA
CAAGTCGTTAGTAATTCGCTTTTCTTGTTTTACTGATGTGCCAATATTTTTTGAATCTGTGTGT
TTTTATTTATTCCAAGCTGCTTTCCAAATGTGAAATTTTCATTTTCAATGTACTGTTCAAATAT
TTAAGAGACTGAATACTTGTGGTGTATCAGATATGAATGTGAACATGACTTGCCCAACTTCTTG
GGATAGCTAGCACTAAGTTCAGAAGACGATGGTTACTAAAATAACAGAAGGCAATATACGTGTG
CAATCTTAACGTGTCTCAGCATCAACATGGCAAAACCATTTCATTATGAACTTATGATTTGGAT
TAAATTTTAGGTTCCAGGAGACAAGAAGCTGATTTATGAAC

hide sequence

RefSeq Acc Id:

XM_017592497 ⟹ XP_017447986

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	28,947,951 - 28,953,261 (-)	NCBI

Sequence:

show sequence

GATAAACCAATGTTGTGATTCTTGATTAGGGTGCTGACTTCTTACTGGGAAGATTTCACCAGCT
CTACCTTAAAACTTCTACTTAATGAAATCTGTTTGGAATAGATTTCTGATCTCAGAGACCTTAC
TTAGTCCATAAGAATGAACAGTGGATCTGTCTTTCCCGTATCACTCTCATACTTGTGCTGTAGG
ATTCAGCTTTCTTTGCGGTGGAGGTGCAAATTGGCGCCTTGAGCAATCCTCATGGGTCATTTCC
CTCTGGCTAGCCCATTTCCCAGTACTGACACACACGCGTTCCTCAGGCATCACCCGGCTGCGGG
CAAAACTTTGGGAATCAGTCTCAACTTCACAACTCCAGGGAAATTCCTCTTGGGACACATCGAG
CGTGGGAGCGGGATGGGCCACTGCCTCAGTCGTGAATCAGCCACGTTTTGTGCTCCGCCCCGTT
GGGGGTCCAGGGATGATTTAAAGGCCGCTTTTCTGGGAGCAGACGACCAGCACTCTCCTCCCTC
TCTCCGCGCATCCAGGCAGCCGCACCACCCGGTCGTATGGACCCTGCTACATCCCTGAGACTGT
GGAATCTGCCGCTGCTCCTGGGAATAACTTAGAGATCTGCCTCTTGCCTTTGGACATGGGACCT
TGTAAGGCCCTCATCCCCAAGTTCTACTATGACAGGGACCAGAAGAAATGCCGCAGATTCAAGT
ATGGAGGCTGCCTGGGCAATGCCAACAATTTCCACAGTCGGAAACTCTGCGAACACACTTGCGG
AAATAAGGAGAAAGTTCCTTGGGTTTGTCGATCAGCAGTCAGAACGTATCCGTGTGATAAACCC
AATACAGAGTTTTTCTTCAATCTGAAAACTATGACATGTGAGCCTCTTAGGCCTGGTCTGTGTA
GCAGGACTACGAATGTGTTCCCCGAGGAAGCTATGTGTAAGAGCTTATGTGAACCAAGGAAAAG
TATCCCATCATTTTGCTCCAGTCCAAAAGATGAAGGCCTGTGTTCTGCTAATGTGACCCGCTAT
TATTTTAATTCAAGAAACAAAGCCTGCGAGACCTTCACCTACACTGGCTGTGGTGGCAATGAAA
ATAACTTTTATTACCTGGATGCTTGCAACCGTGCCTGTGTTAAAGCCTTGAAGAAGCCCAAGAG
AAGGAAGATAGGTGATTTCCTGCCGAGATTTTGGAAGCTTCGTTCTTAAGCATTTTCTCATACT
CAAGGAAACAAGTCATTAGTAATTTGCTTTTCTTGTTTTACTGATGTGCCAATATTTTTTGAAT
CTGTGTGTTTTTATTTATTCCAAGCTGCTTTCCAAATGTGAAATTTTCATTTTCAATGTACTGT
TCAAATATTTAAGAGACTGAATACTTGTGGTGTATCAGATATGAATGTGAACATGACTTGCCCA
ACTTCTTGGGATAGCTAGCACTAAGTTCAGAAGACGATGGTTACTAAAATAACAGAAGGCAATA
TACGTGTGCAATCTTAACGTGTCTCAGCATCAACATGGCAAAACCATTTCATTATGAACTTATA
GATTTGGATTAAATTTTAGGTTCCAGGAGACAAGAAGCTGATTTATGAACACTTTATTCAATCA
TTCCACTGGGGTAATACTTATACCTTGCCAAGTATACTAGAATTCCTTTCTTGCCAGATTGCAA
TATTATAAAGAAGGAGAGTAATTTCAAAGATATAATTATTATTGGATGAATTTAAAATTGGTAA
TTTATAAAAAGAAAAATATTTTGCCTAGAAAAACATGTCATGATATATTCAAATGTGTTTCTTT
AGTTTTCCATATTCGACAGGTAAAATCTTCTTTGACCATGTGTGTTGCATTACTCCCTCAGACA
AAGTGCTCTGGAGAACAGAAATCAGTGGATCTTTTGTACTATGTAAGATGTATCCTGCACCAAA
ATGCATGTATGATTTAACTTGAATTTTATGAATAAAATTTTTAAAGTGGTTCTTACAA

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Protein Sequences


Protein RefSeqs	NP_775164	(Get FASTA)	NCBI Sequence Viewer
	XP_017447986	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAD22046	(Get FASTA)	NCBI Sequence Viewer
	EDL84390	(Get FASTA)	NCBI Sequence Viewer
	EDL84391	(Get FASTA)	NCBI Sequence Viewer
	EDL84392	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_775164 ⟸ NM_173141

- Peptide Label:

precursor

- Sequence:

show sequence

MDPATSLRLWNLPLLLVGSALGLASVSAQGNNLEICLLPLDMGPCKALIPKFYYDRDQKKCRRF
KYGGCLGNANNFHSRKLCEHTCGNKEKVPWVCRSAVRTYPCDKPNTEFFFNLKTMTCEPLRPGL
CSRTTNVFPEEAMCKSLCEPRKSIPSFCSSPKDEGLCSANVTRYYFNSRNKTCETFTYTGCGGN
ENNFYYLDACNRACVKALKKPKRRKIGDFLPRFWKLRS

hide sequence

RefSeq Acc Id:	XP_017447986 ⟸ XM_017592497
- Peptide Label:	isoform X1
- Sequence:	show sequence MGPCKALIPKFYYDRDQKKCRRFKYGGCLGNANNFHSRKLCEHTCGNKEKVPWVCRSAVRTYPC DKPNTEFFFNLKTMTCEPLRPGLCSRTTNVFPEEAMCKSLCEPRKSIPSFCSSPKDEGLCSANV TRYYFNSRNKACETFTYTGCGGNENNFYYLDACNRACVKALKKPKRRKIGDFLPRFWKLRS hide sequence

RefSeq Acc Id:

ENSRNOP00000013989 ⟸ ENSRNOT00000013989

Protein Domains

BPTI/Kunitz inhibitor

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692854

Promoter ID:

EPDNEW_R3378

Type:

single initiation site

Name:

Tfpi2_1

Description:

tissue factor pathway inhibitor 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	28,952,769 - 28,952,829	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628629	AgrOrtholog
Ensembl Genes	ENSRNOG00000010513	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000013989	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013989	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	4.10.410.10	UniProtKB/TrEMBL
InterPro	Kunitz_BPTI_sf	UniProtKB/TrEMBL
	Prot_inh_Kunz-m	UniProtKB/TrEMBL
	Prtase_inh_Kunz-CS	UniProtKB/TrEMBL
	TFPI-like	UniProtKB/TrEMBL
KEGG Report	rno:286926	UniProtKB/TrEMBL
NCBI Gene	286926	ENTREZGENE
Pfam	Kunitz_BPTI	UniProtKB/TrEMBL
PhenoGen	Tfpi2	PhenoGen
PIRSF	TFPI	UniProtKB/TrEMBL
PRINTS	BASICPTASE	UniProtKB/TrEMBL
PROSITE	BPTI_KUNITZ_1	UniProtKB/TrEMBL
	BPTI_KUNITZ_2	UniProtKB/TrEMBL
SMART	SM00131	UniProtKB/TrEMBL
Superfamily-SCOP	Prot_inh_Kunz-m	UniProtKB/TrEMBL
UniGene	Rn.15776	ENTREZGENE
UniProt	G3V7D5_RAT	UniProtKB/TrEMBL
	Q8CF99_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-02-26	Tfpi2	tissue factor pathway inhibitor 2			Symbol and Name status set to approved	625702	APPROVED
2003-02-27	Tfpi2	tissue factor pathway inhibitor 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD