Anxa7 (annexin A7) - Rat Genome Database

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Gene: Anxa7 (annexin A7) Rattus norvegicus
Analyze
Symbol: Anxa7
Name: annexin A7
RGD ID: 621173
Description: Enables calcium-dependent phospholipid binding activity. Involved in membrane fusion; response to calcium ion; and response to organic cyclic compound. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum membrane; and nuclear envelope. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Predicted to colocalize with chromaffin granule membrane. Orthologous to human ANXA7 (annexin A7); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8153,869,180 - 3,897,827 (+)NCBIGRCr8
mRatBN7.2153,821,798 - 3,849,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl153,821,845 - 3,849,385 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx153,831,970 - 3,858,757 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,218,394 - 5,245,181 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,830,787 - 3,857,575 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,254,470 - 4,281,296 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,254,499 - 4,281,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0158,355,756 - 8,382,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4154,047,956 - 4,075,981 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1154,047,987 - 4,077,036 (+)NCBI
Celera15746,369 - 773,156 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methoxyethanol  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (ISO)
benzatropine  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cefaloridine  (EXP)
cisplatin  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
coumarin  (EXP)
crocidolite asbestos  (ISO)
cyproconazole  (ISO)
deguelin  (ISO)
dibutyl phthalate  (EXP,ISO)
disodium selenite  (ISO)
diuron  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
etoposide  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
Hexachloro-1,3-butadiene  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
ivermectin  (ISO)
leflunomide  (EXP)
methidathion  (ISO)
microcystin-LR  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
Nonylphenol  (EXP)
ozone  (EXP,ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
picoxystrobin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
propiconazole  (ISO)
quartz  (ISO)
silicon dioxide  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Calcium ionophore and phorbol ester increase membrane binding of annexin a7 in alveolar type II cells. Chander A, etal., Cell Calcium 2003 Jan;33(1):11-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Partial truncation of the NH2-terminus affects physical characteristics and membrane binding, aggregation, and fusion properties of annexin A7. Naidu DG, etal., Biochim Biophys Acta. 2005 May 15;1734(2):152-68. Epub 2005 Apr 13.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Prognostic impact of ANX7-GTPase in metastatic and HER2-negative breast cancer patients. Srivastava M, etal., Clin Cancer Res. 2004 Apr 1;10(7):2344-50.
12. ANXA7 expression represents hormone-relevant tumor suppression in different cancers. Srivastava M, etal., Int J Cancer. 2007 Dec 15;121(12):2628-36.
13. Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse. Srivastava M, etal., Proc Natl Acad Sci U S A 1999 Nov 23;96(24):13783-8.
14. ANX7, a candidate tumor suppressor gene for prostate cancer. Srivastava M, etal., Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4575-80. Epub 2001 Apr 3.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9268363   PMID:10672515   PMID:12445460   PMID:12925238   PMID:14644162   PMID:15819996   PMID:16843057   PMID:19056867   PMID:19199708   PMID:19946888   PMID:20458337   PMID:21034558  
PMID:21492153   PMID:21531385   PMID:22681889   PMID:22713544   PMID:23376485   PMID:23434680   PMID:23533145   PMID:24007983   PMID:29196215  


Genomics

Comparative Map Data
Anxa7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8153,869,180 - 3,897,827 (+)NCBIGRCr8
mRatBN7.2153,821,798 - 3,849,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl153,821,845 - 3,849,385 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx153,831,970 - 3,858,757 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,218,394 - 5,245,181 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,830,787 - 3,857,575 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0154,254,470 - 4,281,296 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl154,254,499 - 4,281,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0158,355,756 - 8,382,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4154,047,956 - 4,075,981 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1154,047,987 - 4,077,036 (+)NCBI
Celera15746,369 - 773,156 (-)NCBICelera
Cytogenetic Map15p16NCBI
ANXA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381073,375,101 - 73,414,058 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1073,375,101 - 73,414,076 (-)EnsemblGRCh38hg38GRCh38
GRCh371075,134,859 - 75,173,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361074,805,210 - 74,843,809 (-)NCBINCBI36Build 36hg18NCBI36
Build 341074,805,209 - 74,843,814NCBI
Celera1068,420,787 - 68,459,438 (-)NCBICelera
Cytogenetic Map10q22.2NCBI
HuRef1069,129,017 - 69,167,555 (-)NCBIHuRef
CHM1_11075,416,936 - 75,455,602 (-)NCBICHM1_1
T2T-CHM13v2.01074,246,516 - 74,285,473 (-)NCBIT2T-CHM13v2.0
Anxa7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,505,344 - 20,530,009 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1420,505,328 - 20,530,201 (-)EnsemblGRCm39 Ensembl
GRCm381420,455,261 - 20,480,133 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,455,260 - 20,480,133 (-)EnsemblGRCm38mm10GRCm38
MGSCv371421,274,483 - 21,299,355 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361419,243,829 - 19,268,368 (-)NCBIMGSCv36mm8
Celera1416,836,477 - 16,861,550 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.53NCBI
Anxa7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543718,394,371 - 18,421,779 (+)NCBIChiLan1.0ChiLan1.0
ANXA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2885,536,646 - 85,590,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11085,541,969 - 85,595,664 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01069,923,353 - 69,962,980 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11072,381,438 - 72,421,876 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1072,381,447 - 72,420,749 (-)Ensemblpanpan1.1panPan2
ANXA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1423,933,959 - 23,961,968 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl423,934,234 - 23,961,880 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha424,071,745 - 24,099,755 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0424,214,127 - 24,242,151 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl424,214,179 - 24,242,087 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1424,111,654 - 24,139,673 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0424,312,100 - 24,340,096 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0424,666,997 - 24,695,008 (-)NCBIUU_Cfam_GSD_1.0
Anxa7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721357,146,447 - 57,179,174 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365215,651,719 - 5,671,050 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365215,639,193 - 5,671,369 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANXA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1476,205,232 - 76,234,631 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11476,205,238 - 76,234,646 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21482,330,905 - 82,360,163 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANXA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1957,863,482 - 57,900,972 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl957,863,546 - 57,900,324 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604818,444,489 - 18,484,974 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anxa7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247546,992,436 - 7,022,419 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Anxa7
129 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:192
Count of miRNA genes:136
Interacting mature miRNAs:147
Transcripts:ENSRNOT00000061686
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15105825014481294Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15226636822711984Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat

Markers in Region
D15Got1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2153,830,919 - 3,831,049 (+)MAPPERmRatBN7.2
Rnor_6.0154,263,605 - 4,263,732NCBIRnor6.0
Rnor_5.0158,364,863 - 8,364,990UniSTSRnor5.0
RGSC_v3.4154,058,299 - 4,058,427RGDRGSC3.4
RGSC_v3.4154,058,300 - 4,058,427UniSTSRGSC3.4
RGSC_v3.1154,058,300 - 4,058,427RGD
Celera15763,923 - 764,050UniSTS
RH 3.4 Map1565.2UniSTS
RH 3.4 Map1565.2RGD
RH 2.0 Map150.0RGD
Cytogenetic Map15p16UniSTS
RH128488  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2153,848,265 - 3,848,464 (+)MAPPERmRatBN7.2
mRatBN7.22178,286,618 - 178,286,817 (+)MAPPERmRatBN7.2
Rnor_6.02192,971,444 - 192,971,642NCBIRnor6.0
Rnor_6.0154,280,952 - 4,281,150NCBIRnor6.0
Rnor_5.0158,382,207 - 8,382,405UniSTSRnor5.0
Rnor_5.02211,898,636 - 211,898,834UniSTSRnor5.0
RGSC_v3.42185,695,785 - 185,695,983UniSTSRGSC3.4
RGSC_v3.4154,075,644 - 4,075,842UniSTSRGSC3.4
Celera15746,508 - 746,706UniSTS
Celera2171,973,391 - 171,973,589UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map15p16UniSTS
RH129297  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2153,848,382 - 3,848,570 (+)MAPPERmRatBN7.2
Rnor_6.0154,281,069 - 4,281,256NCBIRnor6.0
Rnor_5.0158,382,324 - 8,382,511UniSTSRnor5.0
RGSC_v3.4154,075,761 - 4,075,948UniSTSRGSC3.4
Celera15746,402 - 746,589UniSTS
RH 3.4 Map1545.6UniSTS
Cytogenetic Map15p16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 52 36 19 36 8 11 74 35 37 11 8
Low 5 5 5 4
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000061686   ⟹   ENSRNOP00000058397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl153,821,928 - 3,848,603 (+)Ensembl
Rnor_6.0 Ensembl154,254,499 - 4,281,287 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102608   ⟹   ENSRNOP00000079081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl153,826,465 - 3,849,385 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104138   ⟹   ENSRNOP00000080216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl153,821,845 - 3,849,385 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108222   ⟹   ENSRNOP00000090513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl153,822,208 - 3,849,385 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116779   ⟹   ENSRNOP00000091902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl153,821,928 - 3,848,603 (+)Ensembl
RefSeq Acc Id: NM_130416   ⟹   NP_569100
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,871,040 - 3,897,827 (+)NCBI
mRatBN7.2153,821,813 - 3,848,603 (+)NCBI
Rnor_6.0154,254,499 - 4,281,289 (+)NCBI
Rnor_5.0158,355,756 - 8,382,551 (+)NCBI
RGSC_v3.4154,047,956 - 4,075,981 (+)RGD
Celera15746,369 - 773,156 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251624   ⟹   XP_006251686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,871,365 - 3,897,827 (+)NCBI
mRatBN7.2153,822,229 - 3,849,659 (+)NCBI
Rnor_6.0154,254,818 - 4,281,296 (+)NCBI
Rnor_5.0158,355,756 - 8,382,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251625   ⟹   XP_006251687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,869,180 - 3,897,827 (+)NCBI
mRatBN7.2153,821,814 - 3,849,659 (+)NCBI
Rnor_6.0154,254,470 - 4,281,296 (+)NCBI
Rnor_5.0158,355,756 - 8,382,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251626   ⟹   XP_006251688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,869,180 - 3,897,827 (+)NCBI
mRatBN7.2153,821,798 - 3,849,659 (+)NCBI
Rnor_6.0154,254,603 - 4,281,296 (+)NCBI
Rnor_5.0158,355,756 - 8,382,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251627   ⟹   XP_006251689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,871,206 - 3,897,827 (+)NCBI
mRatBN7.2153,822,229 - 3,849,659 (+)NCBI
Rnor_6.0154,254,819 - 4,281,296 (+)NCBI
Rnor_5.0158,355,756 - 8,382,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063273920   ⟹   XP_063129990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8153,871,232 - 3,897,827 (+)NCBI
RefSeq Acc Id: NP_569100   ⟸   NM_130416
- UniProtKB: Q6IRJ7 (UniProtKB/TrEMBL),   A0A8I5ZQ42 (UniProtKB/TrEMBL),   Q8VIN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251687   ⟸   XM_006251625
- Peptide Label: isoform X2
- UniProtKB: F7F6D1 (UniProtKB/TrEMBL),   Q8VIN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251688   ⟸   XM_006251626
- Peptide Label: isoform X2
- UniProtKB: F7F6D1 (UniProtKB/TrEMBL),   Q8VIN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251686   ⟸   XM_006251624
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006251689   ⟸   XM_006251627
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000058397   ⟸   ENSRNOT00000061686
RefSeq Acc Id: ENSRNOP00000079081   ⟸   ENSRNOT00000102608
RefSeq Acc Id: ENSRNOP00000091902   ⟸   ENSRNOT00000116779
RefSeq Acc Id: ENSRNOP00000080216   ⟸   ENSRNOT00000104138
RefSeq Acc Id: ENSRNOP00000090513   ⟸   ENSRNOT00000108222
RefSeq Acc Id: XP_063129990   ⟸   XM_063273920
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IRJ7-F1-model_v2 AlphaFold Q6IRJ7 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699564
Promoter ID:EPDNEW_R10088
Type:initiation region
Name:Anxa7_1
Description:annexin A7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0154,254,620 - 4,254,680EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621173 AgrOrtholog
BioCyc Gene G2FUF-14538 BioCyc
Ensembl Genes ENSRNOG00000007136 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061686.4 UniProtKB/TrEMBL
  ENSRNOT00000102608.1 UniProtKB/TrEMBL
  ENSRNOT00000104138.1 UniProtKB/TrEMBL
  ENSRNOT00000108222.1 UniProtKB/TrEMBL
  ENSRNOT00000116779 ENTREZGENE
  ENSRNOT00000116779.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7099644 IMAGE-MGC_LOAD
InterPro Annexin UniProtKB/TrEMBL
  Annexin_repeat UniProtKB/TrEMBL
  Annexin_repeat_CS UniProtKB/TrEMBL
  Annexin_sf UniProtKB/TrEMBL
KEGG Report rno:155423 UniProtKB/TrEMBL
MGC_CLONE MGC:91520 IMAGE-MGC_LOAD
NCBI Gene 155423 ENTREZGENE
PANTHER ANNEXIN UniProtKB/TrEMBL
  ANNEXIN A7 UniProtKB/TrEMBL
Pfam Annexin UniProtKB/TrEMBL
PhenoGen Anxa7 PhenoGen
PRINTS ANNEXIN UniProtKB/TrEMBL
  ANNEXINVII UniProtKB/TrEMBL
PROSITE ANNEXIN UniProtKB/TrEMBL
  ANNEXIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007136 RatGTEx
SMART ANX UniProtKB/TrEMBL
Superfamily-SCOP SSF47874 UniProtKB/TrEMBL
UniProt A0A8I5ZM12_RAT UniProtKB/TrEMBL
  A0A8I5ZQ42 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9P3_RAT UniProtKB/TrEMBL
  A0A8I6AH11_RAT UniProtKB/TrEMBL
  F7F6D1 ENTREZGENE, UniProtKB/TrEMBL
  Q6IRJ7 ENTREZGENE, UniProtKB/TrEMBL
  Q8VIN2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Anxa7  annexin A7      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Anxa7  annexin A7      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_process mediates the fusion of lamellar body with plasma membrane 634602
gene_regulation binding to the membrane fraction greatly enhanced by calcium ionophore (A23187) or phorbol 12-myristate 13-acetate (PMA); the PMA effect blocked by protein kinase inhibitors 634602