Gene: Dab2 (DAB2, clathrin adaptor protein) Rattus norvegicus
Symbol: Dab2
Name: DAB2, clathrin adaptor protein
Description: ENCODES a protein that exhibits AP-2 adaptor complex binding (ortholog); cargo receptor activity (ortholog); clathrin adaptor activity (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus; cellular response to transforming growth factor beta stimulus; clathrin coat assembly; PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH Brain Injuries; Experimental Autoimmune Encephalomyelitis; metabolic acidosis; FOUND IN clathrin-coated vesicle membrane; perinuclear region of cytoplasm; plasma membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol
Type: protein-coding
Also known as: adaptor molecule disabled-2; C9; differentially expressed in ovarian carcinoma 2; disabled 2, mitogen-responsive phosphoprotein; disabled homolog 2; disabled homolog 2 (Drosophila); disabled homolog 2 mitogen-responsive phosphoprotein; disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila); Doc-2; DOC-2 p82 isoform; Doc2; mitogen-responsive phosphoprotein
Homo sapiens (human) : DAB2 (DAB2, clathrin adaptor protein)  HGNC  Alliance
Mus musculus (house mouse) : Dab2 (disabled 2, mitogen-responsive phosphoprotein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dab2 (DAB2, clathrin adaptor protein)
Pan paniscus (bonobo/pygmy chimpanzee) : DAB2 (DAB2, clathrin adaptor protein)
Canis lupus familiaris (dog) : DAB2 (DAB2, clathrin adaptor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dab2 (DAB2, clathrin adaptor protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0255,747,353 - 55,768,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0275,489,435 - 75,510,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,714,874 - 55,736,370 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1255,643,109 - 55,664,600 (+)NCBI
Celera251,166,390 - 51,187,877 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dab2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621007
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-11-20
Status: ACTIVE