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Gene: Mras (muscle RAS oncogene homolog) Rattus norvegicus
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Symbol: Mras
Name: muscle RAS oncogene homolog
Description: Predicted to have GTP-dependent protein binding activity; GTPase activity; and purine ribonucleoside binding activity. Predicted to be involved in Ras protein signal transduction and cellular response to leukemia inhibitory factor. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome. Orthologous to human MRAS (muscle RAS oncogene homolog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: muscle and microspikes RAS; ras-related protein M-Ras; ras-related protein R-Ras3
Orthologs:
Homo sapiens (human) : MRAS (muscle RAS oncogene homolog)  HGNC  Alliance
Mus musculus (house mouse) : Mras (muscle and microspikes RAS)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mras (muscle RAS oncogene homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : MRAS (muscle RAS oncogene homolog)
Canis lupus familiaris (dog) : MRAS (muscle RAS oncogene homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mras (muscle RAS oncogene homolog)
Sus scrofa (pig) : MRAS (muscle RAS oncogene homolog)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08107,629,028 - 107,656,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,629,028 - 107,681,512 (-)Ensembl
Rnor_5.08107,054,728 - 107,082,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48104,244,660 - 104,272,556 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18104,264,114 - 104,292,011 (-)NCBI
Celera899,345,811 - 99,373,539 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mras
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3111
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.