MRAS (muscle RAS oncogene homolog) - Rat Genome Database

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Gene: MRAS (muscle RAS oncogene homolog) Pan paniscus
Analyze
Symbol: MRAS
Name: muscle RAS oncogene homolog
RGD ID: 11923581
Description: ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Disease (ortholog); FOUND IN endomembrane system (inferred); membrane (inferred); protein phosphatase type 1 complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein M-Ras
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,253,974 - 136,311,964 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,258,713 - 136,316,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03135,377,488 - 135,435,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13142,827,020 - 142,884,582 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3142,827,020 - 142,884,582 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MRAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,253,974 - 136,311,964 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,258,713 - 136,316,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03135,377,488 - 135,435,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13142,827,020 - 142,884,582 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3142,827,020 - 142,884,582 (+)Ensemblpanpan1.1panPan2
MRAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383138,347,648 - 138,405,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3138,347,648 - 138,405,534 (+)EnsemblGRCh38hg38GRCh38
GRCh373138,066,490 - 138,124,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363139,549,315 - 139,607,067 (+)NCBINCBI36Build 36hg18NCBI36
Build 343139,574,404 - 139,607,073NCBI
Celera3136,491,513 - 136,549,286 (+)NCBICelera
Cytogenetic Map3q22.3NCBI
HuRef3135,441,552 - 135,499,356 (+)NCBIHuRef
CHM1_13138,030,261 - 138,088,159 (+)NCBICHM1_1
T2T-CHM13v2.03141,088,198 - 141,146,101 (+)NCBIT2T-CHM13v2.0
Mras
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39999,267,473 - 99,319,505 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl999,267,473 - 99,319,434 (-)EnsemblGRCm39 Ensembl
GRCm38999,385,420 - 99,437,700 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,385,420 - 99,437,381 (-)EnsemblGRCm38mm10GRCm38
MGSCv37999,285,839 - 99,337,131 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36999,197,328 - 99,246,063 (-)NCBIMGSCv36mm8
Celera998,920,430 - 98,971,712 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.63NCBI
Mras
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,823,374 - 108,886,104 (-)NCBIGRCr8
mRatBN7.2899,944,036 - 100,006,771 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,944,036 - 99,996,408 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8105,610,343 - 105,663,748 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,809,642 - 103,863,053 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08101,652,159 - 101,705,561 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08107,629,028 - 107,656,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,629,028 - 107,681,512 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08107,054,728 - 107,082,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48104,244,660 - 104,272,556 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18104,264,114 - 104,292,011 (-)NCBI
Celera899,345,811 - 99,373,539 (-)NCBICelera
Cytogenetic Map8q31NCBI
Mras
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955501615,303 - 670,782 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955501615,303 - 670,404 (-)NCBIChiLan1.0ChiLan1.0
MRAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12334,558,278 - 34,613,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2334,582,314 - 34,611,763 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2334,550,398 - 34,607,319 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02335,098,326 - 35,155,275 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2335,099,325 - 35,157,728 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12334,779,709 - 34,836,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02334,845,153 - 34,902,406 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02335,096,331 - 35,153,294 (+)NCBIUU_Cfam_GSD_1.0
Mras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560273,933,041 - 73,985,346 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936540672,544 - 725,143 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936540672,783 - 725,129 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1379,139,764 - 79,211,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11379,137,489 - 79,211,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21386,781,175 - 86,826,924 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11552,137,409 - 52,195,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1552,135,727 - 52,170,020 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604125,149,689 - 25,208,288 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mras
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473014,879,484 - 14,940,255 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473014,879,631 - 14,938,683 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000049414   ⟹   ENSPPAP00000026580
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3142,827,020 - 142,884,582 (+)Ensembl
RefSeq Acc Id: XM_003822476   ⟹   XP_003822524
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,253,974 - 136,311,964 (+)NCBI
NHGRI_mPanPan13136,258,713 - 136,316,693 (+)NCBI
Mhudiblu_PPA_v03135,377,488 - 135,435,338 (+)NCBI
PanPan1.13142,827,020 - 142,884,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003822477   ⟹   XP_003822525
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,254,913 - 136,311,964 (+)NCBI
NHGRI_mPanPan13136,259,650 - 136,316,693 (+)NCBI
Mhudiblu_PPA_v03135,378,292 - 135,435,338 (+)NCBI
PanPan1.13142,827,984 - 142,884,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003822478   ⟹   XP_003822526
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,255,245 - 136,311,964 (+)NCBI
NHGRI_mPanPan13136,259,974 - 136,316,693 (+)NCBI
Mhudiblu_PPA_v03135,378,615 - 135,435,338 (+)NCBI
PanPan1.13142,827,990 - 142,884,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976059   ⟹   XP_008974307
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,254,913 - 136,311,964 (+)NCBI
NHGRI_mPanPan13136,259,974 - 136,316,693 (+)NCBI
Mhudiblu_PPA_v03135,378,615 - 135,435,338 (+)NCBI
PanPan1.13142,827,990 - 142,884,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008976060   ⟹   XP_008974308
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,254,906 - 136,308,665 (+)NCBI
NHGRI_mPanPan13136,259,643 - 136,313,394 (+)NCBI
Mhudiblu_PPA_v03135,378,287 - 135,435,338 (+)NCBI
PanPan1.13142,827,984 - 142,884,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024928073   ⟹   XP_024783841
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,254,912 - 136,311,964 (+)NCBI
NHGRI_mPanPan13136,259,974 - 136,316,693 (+)NCBI
Mhudiblu_PPA_v03135,378,615 - 135,435,338 (+)NCBI
PanPan1.13142,827,990 - 142,884,582 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063602954   ⟹   XP_063459024
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22136,255,225 - 136,308,665 (+)NCBI
RefSeq Acc Id: XP_003822524   ⟸   XM_003822476
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BI66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008974308   ⟸   XM_008976060
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003822525   ⟸   XM_003822477
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BI66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003822526   ⟸   XM_003822478
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BI66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008974307   ⟸   XM_008976059
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BI66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024783841   ⟸   XM_024928073
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BI66 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000026580   ⟸   ENSPPAT00000049414
RefSeq Acc Id: XP_063459024   ⟸   XM_063602954
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036377 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049414.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
KEGG Report pps:100973448 UniProtKB/TrEMBL
NCBI Gene MRAS ENTREZGENE
PANTHER PTHR24070 UniProtKB/TrEMBL
  RAS-RELATED PROTEIN M-RAS UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9BI66 ENTREZGENE, UniProtKB/TrEMBL