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Gene: Mras (muscle and microspikes RAS) Mus musculus
Symbol: Mras
Name: muscle and microspikes RAS
RGD ID: 10918
Description: Predicted to have GTP-dependent protein binding activity; GTPase activity; and purine ribonucleoside binding activity. Involved in cellular response to leukemia inhibitory factor. Predicted to localize to plasma membrane. Is expressed in several structures, including brain; branchial arch; dorsal root ganglion; future spinal cord; and limb bud. Human ortholog(s) of this gene implicated in Noonan syndrome. Orthologous to human MRAS (muscle RAS oncogene homolog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900078C09Rik; AI326250; ras-related protein M-Ras; ras-related protein R-Ras3; RIKEN cDNA 2900078C09 gene; X-Ras
Homo sapiens (human) : MRAS (muscle RAS oncogene homolog)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mras (muscle RAS oncogene homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mras (muscle RAS oncogene homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : MRAS (muscle RAS oncogene homolog)
Canis lupus familiaris (dog) : MRAS (muscle RAS oncogene homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mras (muscle RAS oncogene homolog)
Sus scrofa (pig) : MRAS (muscle RAS oncogene homolog)
Chlorocebus sabaeus (African green monkey) : MRAS (muscle RAS oncogene homolog)
Heterocephalus glaber (naked mole-rat) : Mras (muscle RAS oncogene homolog)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39999,267,473 - 99,319,505 (-)NCBI
GRCm38999,385,420 - 99,437,700 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,385,420 - 99,437,381 (-)EnsemblGRCm38mm10GRCm38
MGSCv37999,285,839 - 99,337,131 (-)NCBIGRCm37mm9NCBIm37
MGSCv36999,197,328 - 99,246,063 (-)NCBImm8
Celera998,920,430 - 98,971,712 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mras
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10918
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.