Gene: Smc4 (structural maintenance of chromosomes 4) Rattus norvegicus
Symbol: Smc4
Name: structural maintenance of chromosomes 4
Description: Predicted to have protein heterodimerization activity and single-stranded DNA binding activity; predicted to be involved in chromosome condensation, kinetochore organization, and nuclear division; predicted to localize to the condensin complex, cytosol, and nuclear speck; orthologous to human SMC4 (structural maintenance of chromosomes 4); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC295107; MGC125078; SMC4 structural maintenance of chromosomes 4-like 1; SMC4 structural maintenance of chromosomes 4-like 1 (yeast); Smc4l1; structural maintenance of chromosomes protein 4
Homo sapiens (human) : SMC4 (structural maintenance of chromosomes 4)  HGNC  Alliance
Mus musculus (house mouse) : Smc4 (structural maintenance of chromosomes 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc4 (structural maintenance of chromosomes 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC4 (structural maintenance of chromosomes 4)
Canis lupus familiaris (dog) : SMC4 (structural maintenance of chromosomes 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc4 (structural maintenance of chromosomes 4)
Sus scrofa (pig) : SMC4 (structural maintenance of chromosomes 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02165,600,934 - 165,629,415 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02184,962,125 - 184,990,525 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42158,987,318 - 159,015,705 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12158,937,475 - 158,965,632 (+)NCBI
Celera2147,591,084 - 147,619,494 (+)NCBICelera
Cytogenetic Map2q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Smc4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306680
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.