Elk1 (ETS transcription factor ELK1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Elk1 (ETS transcription factor ELK1) Rattus norvegicus
Analyze
Symbol: Elk1
Name: ETS transcription factor ELK1
RGD ID: 1598663
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in several processes, including cellular response to gamma radiation; cellular response to testosterone stimulus; and hippocampal neuron apoptotic process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in several cellular components, including axon terminus; mitochondrial membrane; and neuronal cell body. Biomarker of anxiety disorder and transient cerebral ischemia. Orthologous to human ELK1 (ETS transcription factor ELK1); PARTICIPATES IN adenosine signaling pathway; hypoxia inducible factor pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH (R)-noradrenaline; (S)-amphetamine; (S)-nicotine.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ELK1, ETS transcription factor; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X1,138,826 - 1,155,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,139,756 - 1,155,713 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,167,915 - 1,183,790 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,643,607 - 4,659,482 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X964,852 - 980,733 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,287,875 - 1,304,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,297,099 - 1,304,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,102,893 - 2,119,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,597,863 - 12,604,248 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX1,708,719 - 1,724,604 (+)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-noradrenaline  (EXP)
(S)-amphetamine  (EXP)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
amphetamine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arsenic acid  (EXP)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
baicalein  (ISO)
baicalin  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP)
curcumin  (ISO)
cycloheximide  (ISO)
daidzein  (EXP)
DDT  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibromoacetic acid  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (ISO)
Enterolactone  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
eticlopride(1+)  (ISO)
galangin  (ISO)
genistein  (ISO)
haloperidol  (EXP,ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
lead(II) chloride  (ISO)
leflunomide  (ISO)
letrozole  (ISO)
mancozeb  (ISO)
maneb  (ISO)
melatonin  (ISO)
methoxyacetic acid  (ISO)
Mitotane  (ISO)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel dichloride  (EXP)
nicotine  (EXP,ISO)
nifedipine  (EXP)
ochratoxin A  (EXP)
ozone  (ISO)
p-anisidine  (ISO)
paclitaxel  (ISO)
paraquat  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
potassium chromate  (ISO)
propranolol  (EXP)
pterostilbene  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
SB 203580  (EXP,ISO)
SCH 23390  (ISO)
serpentine asbestos  (EXP)
SL-327  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
sulindac sulfide  (ISO)
Tanshinone I  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
Tetrachlorobisphenol A  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vecuronium bromide  (ISO)
vemurafenib  (ISO)
vitamin E  (ISO)
wortmannin  (ISO)
zinc atom  (EXP)
zinc dichloride  (EXP)
zinc sulfate  (ISO)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Elk-1 associates with the mitochondrial permeability transition pore complex in neurons. Barrett LE, etal., Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5155-60. Epub 2006 Mar 20.
2. Functional components of basic fibroblast growth factor signaling that inhibit lung elastin gene expression. Carreras I, etal., Am J Physiol Lung Cell Mol Physiol 2001 Oct;281(4):L766-75.
3. Expression of phospho-Elk-1 in rat gut after the whole body gamma irradiation. Driak D, etal., Physiol Res. 2008;57(5):753-9. Epub 2007 Oct 11.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia. Henriksson M, etal., Exp Brain Res. 2007 Apr;178(4):470-6. Epub 2006 Nov 8.
6. Changes in trkB-ERK1/2-CREB/Elk-1 pathways in hippocampal mossy fiber organization after traumatic brain injury. Hu B, etal., J Cereb Blood Flow Metab. 2004 Aug;24(8):934-43.
7. Rapid phosphorylation of Elk-1 transcription factor and activation of MAP kinase signal transduction pathways in response to visual stimulation. Kaminska B, etal., Mol Cell Neurosci. 1999 Jun;13(6):405-14.
8. Increased levels of transcription factors Elk-1, cyclic adenosine monophosphate response element-binding protein, and activating transcription factor 2 in the cerebellar vermis of schizophrenic patients. Kyosseva SV, etal., Arch Gen Psychiatry. 2000 Jul;57(7):685-91.
9. Effector immediate-early gene arc in the amygdala plays a critical role in alcoholism. Pandey SC, etal., J Neurosci. 2008 Mar 5;28(10):2589-600. doi: 10.1523/JNEUROSCI.4752-07.2008.
10. JNK- and Rac1-dependent induction of immediate early gene pip92 suppresses neuronal differentiation. Park JB, etal., J Neurochem. 2007 Jan;100(2):555-66. Epub 2006 Nov 29.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
14. Downstream targets of homeobox gene HLX show altered expression in human idiopathic fetal growth restriction. Rajaraman G, etal., Am J Pathol. 2010 Jan;176(1):278-87. doi: 10.2353/ajpath.2010.090187. Epub 2009 Dec 11.
15. GOA pipeline RGD automated data pipeline
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain. Sgambato V, etal., J Neurosci. 1998 Jan 1;18(1):214-26.
18. A neurotoxic phosphoform of Elk-1 associates with inclusions from multiple neurodegenerative diseases. Sharma A, etal., PLoS One. 2010 Feb 2;5(2):e9002. doi: 10.1371/journal.pone.0009002.
19. The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation. Van Kanegan MJ and Strack S, Mol Cell Biol. 2009 Feb;29(3):662-74. doi: 10.1128/MCB.01242-08. Epub 2008 Nov 24.
20. Androgen inhibition of MAP kinase pathway and Elk-1 activation in proliferating osteoblasts. Wiren KM, etal., J Mol Endocrinol. 2004 Feb;32(1):209-26.
21. Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids. Yoshida T, etal., Am J Physiol Cell Physiol. 2008 Nov;295(5):C1175-82. doi: 10.1152/ajpcell.00288.2008. Epub 2008 Sep 3.
Additional References at PubMed
PMID:8889548   PMID:11050086   PMID:12023815   PMID:12220646   PMID:12391846   PMID:12473665   PMID:12716432   PMID:12750007   PMID:14970218   PMID:15790681   PMID:15896720   PMID:16260603  
PMID:16987998   PMID:17244536   PMID:17296730   PMID:17301675   PMID:17334413   PMID:17505916   PMID:19013529   PMID:19389804   PMID:20018936   PMID:21171386   PMID:21362474   PMID:21677150  
PMID:21678415   PMID:21777515   PMID:21808001   PMID:22065586   PMID:22354998   PMID:22454534   PMID:23516302   PMID:24075908   PMID:26612202   PMID:30053446  


Genomics

Comparative Map Data
Elk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X1,138,826 - 1,155,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,139,756 - 1,155,713 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,167,915 - 1,183,790 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,643,607 - 4,659,482 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X964,852 - 980,733 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,287,875 - 1,304,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,297,099 - 1,304,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,102,893 - 2,119,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,597,863 - 12,604,248 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX1,708,719 - 1,724,604 (+)NCBICelera
Cytogenetic MapXq11NCBI
ELK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,635,520 - 47,650,604 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,635,521 - 47,650,604 (-)EnsemblGRCh38hg38GRCh38
GRCh37X47,494,919 - 47,510,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X47,379,864 - 47,394,964 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X47,251,173 - 47,266,274NCBI
CeleraX51,690,183 - 51,705,266 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX45,207,767 - 45,222,756 (-)NCBIHuRef
CHM1_1X47,526,023 - 47,541,139 (-)NCBICHM1_1
T2T-CHM13v2.0X47,045,421 - 47,060,507 (-)NCBIT2T-CHM13v2.0
Elk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,799,634 - 20,816,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX20,799,634 - 20,816,847 (-)EnsemblGRCm39 Ensembl
GRCm38X20,933,395 - 20,950,608 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,933,395 - 20,950,608 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X20,510,521 - 20,527,726 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X20,091,886 - 20,107,552 (-)NCBIMGSCv36mm8
CeleraX19,067,257 - 19,084,739 (-)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX16.45NCBI
Elk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516430,775 - 444,871 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955516431,081 - 444,871 (+)NCBIChiLan1.0ChiLan1.0
ELK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1X49,265,366 - 49,280,456 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,071,433 - 40,086,518 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X47,967,492 - 47,982,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,967,492 - 47,982,579 (-)Ensemblpanpan1.1panPan2
ELK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,256,205 - 41,270,656 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,257,482 - 41,270,776 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,630,809 - 15,645,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X41,390,004 - 41,404,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX41,390,011 - 41,404,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X41,377,550 - 41,392,091 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,365,833 - 41,380,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X41,458,515 - 41,473,055 (-)NCBIUU_Cfam_GSD_1.0
Elk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,561,981 - 33,577,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650213,402,728 - 13,418,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650213,402,726 - 13,418,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,157,988 - 42,174,951 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,157,980 - 42,174,964 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,303,918 - 47,320,907 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103231899
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X44,812,681 - 44,827,657 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666868398 - 6,908 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624978194,992 - 208,103 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624978194,985 - 208,105 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Elk1
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:618
Count of miRNA genes:284
Interacting mature miRNAs:373
Transcripts:ENSRNOT00000013522
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat

Markers in Region
RH142956  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X1,141,957 - 1,142,089 (+)MAPPERmRatBN7.2
Rnor_6.0X1,291,069 - 1,291,200NCBIRnor6.0
Rnor_5.0X2,106,090 - 2,106,221UniSTSRnor5.0
RGSC_v3.4X12,612,753 - 12,612,884UniSTSRGSC3.4
CeleraX1,710,853 - 1,710,984UniSTS
Cytogenetic MapXq12UniSTS
RH140607  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X1,141,654 - 1,141,860 (+)MAPPERmRatBN7.2
Rnor_6.0X1,290,766 - 1,290,971NCBIRnor6.0
Rnor_5.0X2,105,787 - 2,105,992UniSTSRnor5.0
RGSC_v3.4X12,612,982 - 12,613,187UniSTSRGSC3.4
CeleraX1,710,550 - 1,710,755UniSTS
Cytogenetic MapXq12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 40 15 6 11 6 8 11 74 30 34 11 8
Low 3 42 35 8 35 5 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000013522   ⟹   ENSRNOP00000013522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX1,139,756 - 1,155,713 (+)Ensembl
Rnor_6.0 EnsemblX1,297,099 - 1,304,822 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109793   ⟹   ENSRNOP00000085214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX1,139,878 - 1,155,713 (+)Ensembl
RefSeq Acc Id: NM_001108059   ⟹   NP_001101529
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X1,139,824 - 1,155,713 (+)NCBI
Rnor_6.0X1,288,935 - 1,304,822 (+)NCBI
Rnor_5.0X2,102,893 - 2,119,843 (+)NCBI
RGSC_v3.4X12,597,863 - 12,604,248 (-)RGD
CeleraX1,708,719 - 1,724,604 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256614   ⟹   XP_006256676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X1,138,826 - 1,155,713 (+)NCBI
Rnor_6.0X1,287,875 - 1,304,822 (+)NCBI
Rnor_5.0X2,102,893 - 2,119,843 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001101529   ⟸   NM_001108059
- UniProtKB: A4GTP4 (UniProtKB/TrEMBL),   A0A8I6A3K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256676   ⟸   XM_006256614
- Peptide Label: isoform X1
- UniProtKB: A4GTP4 (UniProtKB/TrEMBL),   A0A8I6A3K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013522   ⟸   ENSRNOT00000013522
RefSeq Acc Id: ENSRNOP00000085214   ⟸   ENSRNOT00000109793

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A4GTP4-F1-model_v2 AlphaFold A4GTP4 1-427 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1598663 AgrOrtholog
BioCyc Gene G2FUF-3203 BioCyc
Ensembl Genes ENSRNOG00000010171 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055016359 UniProtKB/Swiss-Prot
  ENSRNOG00060019596 UniProtKB/Swiss-Prot
  ENSRNOG00065020252 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013522 ENTREZGENE
  ENSRNOT00000013522.6 UniProtKB/Swiss-Prot
  ENSRNOT00000109793.1 UniProtKB/TrEMBL
  ENSRNOT00055027739 UniProtKB/Swiss-Prot
  ENSRNOT00060033863 UniProtKB/Swiss-Prot
  ENSRNOT00065034184 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
InterPro Ets_dom UniProtKB/Swiss-Prot
  ETS_fam UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314436 UniProtKB/Swiss-Prot
NCBI Gene 314436 ENTREZGENE
PANTHER ETS DOMAIN-CONTAINING PROTEIN ELK-1 UniProtKB/Swiss-Prot
  PTHR11849 UniProtKB/Swiss-Prot
Pfam Ets UniProtKB/Swiss-Prot
PhenoGen Elk1 PhenoGen
PRINTS ETSDOMAIN UniProtKB/Swiss-Prot
PROSITE ETS_DOMAIN_1 UniProtKB/Swiss-Prot
  ETS_DOMAIN_2 UniProtKB/Swiss-Prot
  ETS_DOMAIN_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010171 RatGTEx
  ENSRNOG00055016359 RatGTEx
  ENSRNOG00060019596 RatGTEx
  ENSRNOG00065020252 RatGTEx
SMART ETS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A3K1 ENTREZGENE, UniProtKB/TrEMBL
  A4GTP4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Elk1  ETS transcription factor ELK1  Elk1  ELK1, ETS transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-01 Elk1  ELK1, ETS transcription factor  Elk1  ELK1, member of ETS oncogene family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-12-10 Elk1  ELK1, member of ETS oncogene family      Symbol and Name status set to provisional 70820 PROVISIONAL