Prnp Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PRNP mRNA] CTD PMID:31150632 Prnp Rat (1->4)-beta-D-glucan multiple interactions ISO Prnp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRNP mRNA CTD PMID:36331819 Prnp Rat (E)-thiamethoxam increases expression ISO Prnp (Mus musculus) 6480464 Thiamethoxam results in increased expression of PRNP mRNA CTD PMID:33533595 Prnp Rat 1,2-dichloroethane decreases expression ISO Prnp (Mus musculus) 6480464 ethylene dichloride results in decreased expression of PRNP mRNA CTD PMID:28189721 and PMID:28960355 Prnp Rat 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine multiple interactions ISO PRNP (Homo sapiens) 6480464 Copper affects the reaction [1 and 2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 Prnp Rat 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine affects folding ISO PRNP (Homo sapiens) 6480464 1 and 2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form CTD PMID:20936829 Prnp Rat 1,2-dimethylhydrazine decreases expression ISO Prnp (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PRNP mRNA CTD PMID:22206623 Prnp Rat 1,2-dimethylhydrazine multiple interactions ISO Prnp (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRNP mRNA CTD PMID:22206623 Prnp Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of PRNP mRNA CTD PMID:25380136 Prnp Rat 17alpha-ethynylestradiol multiple interactions ISO Prnp (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRNP mRNA CTD PMID:17942748 Prnp Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PRNP mRNA CTD PMID:12075121 Prnp Rat 17beta-estradiol multiple interactions ISO PRNP (Homo sapiens) 6480464 [Estradiol co-treated with EGF protein] results in increased expression of PRNP mRNA CTD PMID:24758408 Prnp Rat 17beta-estradiol increases expression ISO PRNP (Homo sapiens) 6480464 Estradiol results in increased expression of PRNP mRNA CTD PMID:31614463 Prnp Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of PRNP mRNA CTD PMID:32145629 Prnp Rat 17beta-estradiol affects expression ISO PRNP (Homo sapiens) 6480464 Estradiol affects the expression of PRNP mRNA CTD PMID:22574217 Prnp Rat 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO Prnp (Mus musculus) 6480464 Dihydrotestosterone results in decreased expression of PRNP mRNA CTD PMID:17023530 Prnp Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO PRNP (Homo sapiens) 6480464 2 more ... CTD PMID:25305463 Prnp Rat 2,2,2-tetramine increases expression EXP 6480464 Trientine results in increased expression of PRNP mRNA and Trientine results in increased expression of PRNP protein CTD PMID:22362149 Prnp Rat 2,2,2-tetramine affects response to substance EXP 6480464 PRNP protein affects the susceptibility to Trientine CTD PMID:22362149 Prnp Rat 2,2,2-trifluoroethanol affects folding ISO PRNP (Homo sapiens) 6480464 Trifluoroethanol affects the folding of PRNP protein modified form CTD PMID:20936829 Prnp Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Prnp (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRNP mRNA CTD PMID:17942748 Prnp Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PRNP mRNA CTD PMID:33387578 Prnp Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PRNP mRNA CTD PMID:34747641 Prnp Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Prnp (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PRNP mRNA CTD PMID:21570461 Prnp Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Prnp (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Prnp Rat 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of PRNP mRNA CTD PMID:21061450 Prnp Rat 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 Prnp Rat 3,4-dichloroaniline decreases expression ISO PRNP (Homo sapiens) 6480464 3 and 4-dichloroaniline results in decreased expression of PRNP mRNA CTD PMID:24172598 Prnp Rat 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of PRNP mRNA CTD PMID:25380136 Prnp Rat 4,4'-diaminodiphenylmethane decreases expression ISO Prnp (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of PRNP mRNA CTD PMID:18648102 Prnp Rat 4,4'-sulfonyldiphenol increases expression ISO PRNP (Homo sapiens) 6480464 bisphenol S results in increased expression of PRNP protein CTD PMID:34186270 Prnp Rat 5-fluorouracil decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Fluorouracil CTD PMID:15386405 Prnp Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of PRNP mRNA CTD PMID:31881176 Prnp Rat acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of PRNP mRNA CTD PMID:12800193 Prnp Rat acrylamide increases expression ISO PRNP (Homo sapiens) 6480464 Acrylamide results in increased expression of PRNP mRNA CTD PMID:32763439 Prnp Rat aflatoxin B1 decreases expression ISO Prnp (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of PRNP mRNA CTD PMID:19770486 Prnp Rat aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PRNP mRNA CTD PMID:23630614 and PMID:25378103 Prnp Rat aflatoxin B1 increases expression ISO PRNP (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of PRNP mRNA CTD PMID:22100608 Prnp Rat aldehydo-D-glucose multiple interactions ISO PRNP (Homo sapiens) 6480464 [PRNP protein results in increased expression of SLC2A1 protein] which results in increased uptake of Glucose CTD PMID:21265952 Prnp Rat all-trans-retinoic acid decreases expression ISO PRNP (Homo sapiens) 6480464 Tretinoin results in decreased expression of PRNP mRNA CTD PMID:15498508 and PMID:33167477 Prnp Rat all-trans-retinoic acid increases expression ISO PRNP (Homo sapiens) 6480464 Tretinoin results in increased expression of PRNP mRNA CTD PMID:21934132 and PMID:23724009 Prnp Rat all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of PRNP mRNA CTD PMID:20488242 Prnp Rat allopurinol increases expression EXP 6480464 Allopurinol results in increased expression of PRNP mRNA CTD PMID:37876353 Prnp Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PRNP mRNA CTD PMID:16483693 Prnp Rat antirheumatic drug decreases expression ISO PRNP (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of PRNP mRNA CTD PMID:24449571 Prnp Rat arsenite(3-) multiple interactions ISO PRNP (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to PRNP protein] CTD PMID:32406909 Prnp Rat arsenous acid multiple interactions ISO PRNP (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRNP protein] CTD PMID:26598702 Prnp Rat atrazine decreases expression ISO PRNP (Homo sapiens) 6480464 Atrazine results in decreased expression of PRNP mRNA CTD PMID:22378314 Prnp Rat bathocuproine disulfonic acid multiple interactions EXP 6480464 bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein] CTD PMID:16148034 Prnp Rat benzene increases expression ISO PRNP (Homo sapiens) 6480464 Benzene results in increased expression of PRNP mRNA CTD PMID:20359517 Prnp Rat benzo[a]pyrene multiple interactions ISO Prnp (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PRNP promoter] CTD PMID:19654925 Prnp Rat benzo[a]pyrene increases methylation ISO PRNP (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of PRNP promoter CTD PMID:27901495 Prnp Rat benzo[a]pyrene affects methylation ISO PRNP (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PRNP 5' UTR CTD PMID:27901495 Prnp Rat benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PRNP mRNA CTD PMID:21839799 Prnp Rat benzo[a]pyrene diol epoxide I increases expression ISO PRNP (Homo sapiens) 6480464 7 more ... CTD PMID:26238291 Prnp Rat benzoates increases expression ISO PRNP (Homo sapiens) 6480464 Benzoates analog results in increased expression of PRNP mRNA CTD PMID:29472718 Prnp Rat beta-lapachone increases expression ISO PRNP (Homo sapiens) 6480464 beta-lapachone results in increased expression of PRNP mRNA CTD PMID:38218311 Prnp Rat bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of PRNP mRNA CTD PMID:16648578 Prnp Rat bis(2-ethylhexyl) phthalate increases expression ISO Prnp (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of PRNP mRNA CTD PMID:33754040 Prnp Rat bisphenol A decreases expression ISO PRNP (Homo sapiens) 6480464 bisphenol A results in decreased expression of PRNP mRNA CTD PMID:20678512 Prnp Rat bisphenol A increases expression ISO PRNP (Homo sapiens) 6480464 bisphenol A results in increased expression of PRNP mRNA and bisphenol A results in increased expression of PRNP protein CTD PMID:29275510 and PMID:34186270 Prnp Rat bisphenol A affects expression ISO PRNP (Homo sapiens) 6480464 bisphenol A affects the expression of PRNP mRNA CTD PMID:30903817 Prnp Rat bisphenol A affects methylation ISO Prnp (Mus musculus) 6480464 bisphenol A affects the methylation of PRNP promoter CTD PMID:27334623 Prnp Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PRNP mRNA CTD PMID:25181051 Prnp Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PRNP mRNA CTD PMID:12075121 and PMID:32145629 Prnp Rat bisphenol AF increases expression ISO PRNP (Homo sapiens) 6480464 bisphenol AF results in increased expression of PRNP protein CTD PMID:34186270 Prnp Rat Bisphenol B increases expression ISO PRNP (Homo sapiens) 6480464 bisphenol B results in increased expression of PRNP protein CTD PMID:34186270 Prnp Rat bortezomib increases expression ISO PRNP (Homo sapiens) 6480464 Bortezomib results in increased expression of PRNP mRNA CTD PMID:20977926 Prnp Rat butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of PRNP mRNA CTD PMID:12800193 Prnp Rat cadmium atom increases ubiquitination ISO Prnp (Mus musculus) 6480464 Cadmium results in increased ubiquitination of PRNP protein CTD PMID:22995398 Prnp Rat cadmium atom multiple interactions ISO PRNP (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRNP mRNA CTD PMID:35301059 Prnp Rat cadmium dichloride increases expression ISO PRNP (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of PRNP mRNA CTD PMID:12760830 Prnp Rat cadmium dichloride multiple interactions ISO PRNP (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRNP mRNA CTD PMID:35301059 Prnp Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of PRNP mRNA CTD PMID:16148034 Prnp Rat caffeine decreases expression ISO PRNP (Homo sapiens) 6480464 Caffeine results in decreased expression of PRNP mRNA CTD PMID:18444173 Prnp Rat calcitriol increases expression ISO PRNP (Homo sapiens) 6480464 Calcitriol results in increased expression of PRNP mRNA CTD PMID:16002434 Prnp Rat carbamazepine affects expression ISO PRNP (Homo sapiens) 6480464 Carbamazepine affects the expression of PRNP mRNA CTD PMID:25979313 Prnp Rat carbon nanotube increases expression ISO Prnp (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of PRNP mRNA CTD PMID:25554681 Prnp Rat CGP 52608 multiple interactions ISO PRNP (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PRNP gene] CTD PMID:28238834 Prnp Rat chloropicrin decreases expression ISO PRNP (Homo sapiens) 6480464 chloropicrin results in decreased expression of PRNP mRNA CTD PMID:26352163 Prnp Rat chlorpyrifos increases expression ISO Prnp (Mus musculus) 6480464 Chlorpyrifos results in increased expression of PRNP mRNA CTD PMID:32715474 Prnp Rat chromium(6+) multiple interactions ISO PRNP (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of PRNP mRNA CTD PMID:38479592 Prnp Rat cisplatin decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Cisplatin CTD PMID:15386405 Prnp Rat Congo Red decreases expression ISO Prnp (Mus musculus) 6480464 Congo Red results in decreased expression of PRNP protein alternative form CTD PMID:11994310 Prnp Rat copper atom affects binding ISO PRNP (Homo sapiens) 6480464 Copper binds to PRNP protein more ... CTD PMID:16824036 more ... Prnp Rat copper atom decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Copper CTD PMID:21537833 Prnp Rat copper atom decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Copper CTD PMID:12500977 and PMID:16787422 Prnp Rat copper atom increases reduction ISO PRNP (Homo sapiens) 6480464 PRNP protein results in increased reduction of Copper CTD PMID:12572668 Prnp Rat copper atom increases cleavage ISO PRNP (Homo sapiens) 6480464 Copper results in increased cleavage of PRNP protein CTD PMID:19597535 Prnp Rat copper atom increases transport ISO Prnp (Mus musculus) 6480464 Copper results in increased transport of PRNP protein CTD PMID:21172064 Prnp Rat copper atom affects folding ISO PRNP (Homo sapiens) 6480464 Copper affects the folding of PRNP protein modified form CTD PMID:20936829 Prnp Rat copper atom increases uptake EXP 6480464 PRNP protein results in increased uptake of Copper CTD PMID:19957168 and PMID:22362149 Prnp Rat copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of PRNP mRNA more ... CTD PMID:22362149 and PMID:22465980 Prnp Rat copper atom multiple interactions EXP 6480464 [PRNP protein results in increased uptake of Copper] which results in increased activity of SOD1 protein CTD PMID:22362149 Prnp Rat copper atom increases uptake ISO Prnp (Mus musculus) 6480464 Copper results in increased uptake of PRNP protein CTD PMID:17155929 Prnp Rat copper atom affects binding ISO Prnp (Mus musculus) 6480464 Copper binds to PRNP protein and PRNP protein binds to Copper CTD PMID:12500977 more ... Prnp Rat copper atom multiple interactions ISO PRNP (Homo sapiens) 6480464 [[[Copper binds to PRNP protein] which results in increased reduction of Copper] which results in increased abundance of Reactive Oxygen Species] which results in increased cleavage of PRNP protein more ... CTD PMID:17112476 more ... Prnp Rat copper atom multiple interactions ISO Prnp (Mus musculus) 6480464 [[Hydrogen Peroxide co-treated with Copper] results in increased cleavage of PRNP protein] promotes the reaction [PRNP protein binds to PRNP protein] more ... CTD PMID:15467011 more ... Prnp Rat copper(0) affects binding ISO PRNP (Homo sapiens) 6480464 Copper binds to PRNP protein more ... CTD PMID:16824036 more ... Prnp Rat copper(0) decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Copper CTD PMID:21537833 Prnp Rat copper(0) decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Copper CTD PMID:12500977 and PMID:16787422 Prnp Rat copper(0) increases reduction ISO PRNP (Homo sapiens) 6480464 PRNP protein results in increased reduction of Copper CTD PMID:12572668 Prnp Rat copper(0) increases cleavage ISO PRNP (Homo sapiens) 6480464 Copper results in increased cleavage of PRNP protein CTD PMID:19597535 Prnp Rat copper(0) increases transport ISO Prnp (Mus musculus) 6480464 Copper results in increased transport of PRNP protein CTD PMID:21172064 Prnp Rat copper(0) affects folding ISO PRNP (Homo sapiens) 6480464 Copper affects the folding of PRNP protein modified form CTD PMID:20936829 Prnp Rat copper(0) increases uptake EXP 6480464 PRNP protein results in increased uptake of Copper CTD PMID:19957168 and PMID:22362149 Prnp Rat copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of PRNP mRNA more ... CTD PMID:22362149 and PMID:22465980 Prnp Rat copper(0) multiple interactions EXP 6480464 [PRNP protein results in increased uptake of Copper] which results in increased activity of SOD1 protein CTD PMID:22362149 Prnp Rat copper(0) increases uptake ISO Prnp (Mus musculus) 6480464 Copper results in increased uptake of PRNP protein CTD PMID:17155929 Prnp Rat copper(0) affects binding ISO Prnp (Mus musculus) 6480464 Copper binds to PRNP protein and PRNP protein binds to Copper CTD PMID:12500977 more ... Prnp Rat copper(0) multiple interactions ISO PRNP (Homo sapiens) 6480464 [[[Copper binds to PRNP protein] which results in increased reduction of Copper] which results in increased abundance of Reactive Oxygen Species] which results in increased cleavage of PRNP protein more ... CTD PMID:17112476 more ... Prnp Rat copper(0) multiple interactions ISO Prnp (Mus musculus) 6480464 [[Hydrogen Peroxide co-treated with Copper] results in increased cleavage of PRNP protein] promotes the reaction [PRNP protein binds to PRNP protein] more ... CTD PMID:15467011 more ... Prnp Rat copper(II) chloride multiple interactions ISO Prnp (Mus musculus) 6480464 [NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein] CTD PMID:16990274 Prnp Rat copper(II) chloride multiple interactions EXP 6480464 bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein] CTD PMID:16148034 Prnp Rat copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of PRNP mRNA and cupric chloride results in increased expression of PRNP protein CTD PMID:16148034 Prnp Rat copper(II) sulfate affects binding ISO PRNP (Homo sapiens) 6480464 PRNP protein binds to Copper Sulfate and PRNP protein polymorphism binds to Copper Sulfate CTD PMID:16847141 Prnp Rat copper(II) sulfate multiple interactions ISO Prnp (Mus musculus) 6480464 Copper Sulfate results in increased uptake of and affects the localization of PRNP protein more ... CTD PMID:11994310 Prnp Rat copper(II) sulfate multiple interactions ISO PRNP (Homo sapiens) 6480464 Copper Sulfate results in increased uptake of and affects the localization of PRNP protein more ... CTD PMID:11994310 Prnp Rat copper(II) sulfate increases expression ISO PRNP (Homo sapiens) 6480464 Copper Sulfate results in increased expression of PRNP mRNA CTD PMID:19549813 Prnp Rat copper(II) sulfate affects binding ISO Prnp (Mus musculus) 6480464 PRNP protein binds to Copper Sulfate CTD PMID:16787422 Prnp Rat copper(II) sulfate decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Copper Sulfate CTD PMID:16787422 Prnp Rat cyclosporin A increases expression ISO Prnp (Mus musculus) 6480464 Cyclosporine results in increased expression of PRNP mRNA CTD PMID:19770486 Prnp Rat cyclosporin A increases expression ISO PRNP (Homo sapiens) 6480464 Cyclosporine results in increased expression of PRNP mRNA CTD PMID:20106945 and PMID:25562108 Prnp Rat cytarabine decreases expression ISO PRNP (Homo sapiens) 6480464 Cytarabine results in decreased expression of PRNP mRNA CTD PMID:21198554 Prnp Rat D-glucose multiple interactions ISO PRNP (Homo sapiens) 6480464 [PRNP protein results in increased expression of SLC2A1 protein] which results in increased uptake of Glucose CTD PMID:21265952 Prnp Rat diarsenic trioxide multiple interactions ISO PRNP (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PRNP protein] CTD PMID:26598702 Prnp Rat dichloromethane increases expression ISO PRNP (Homo sapiens) 6480464 Methylene Chloride results in increased expression of PRNP mRNA CTD PMID:20359517 Prnp Rat diethyldithiocarbamic acid increases expression EXP 6480464 Ditiocarb results in increased expression of PRNP protein CTD PMID:20452388 Prnp Rat dioxygen increases expression ISO PRNP (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of PRNP mRNA and Oxygen deficiency results in increased expression of PRNP protein CTD PMID:17387271 Prnp Rat dioxygen decreases expression ISO PRNP (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of PRNP mRNA CTD PMID:35883890 Prnp Rat dioxygen multiple interactions ISO Prnp (Mus musculus) 6480464 Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of PRNP mRNA] CTD PMID:22629407 Prnp Rat dioxygen increases expression ISO Prnp (Mus musculus) 6480464 Oxygen deficiency results in increased expression of PRNP mRNA CTD PMID:22629407 Prnp Rat dioxygen multiple interactions ISO PRNP (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of PRNP mRNA] CTD PMID:17387271 Prnp Rat diuron decreases expression ISO PRNP (Homo sapiens) 6480464 Diuron metabolite results in decreased expression of PRNP mRNA CTD PMID:24172598 Prnp Rat dorsomorphin multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Prnp Rat doxorubicin decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Doxorubicin CTD PMID:15386405 Prnp Rat edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [PRNP protein alternative form results in decreased activity of SOD1 protein] more ... CTD PMID:20806394 Prnp Rat entinostat increases expression ISO PRNP (Homo sapiens) 6480464 entinostat results in increased expression of PRNP mRNA CTD PMID:26272509 Prnp Rat entinostat multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRNP mRNA CTD PMID:27188386 Prnp Rat ethyl methanesulfonate increases expression ISO PRNP (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of PRNP mRNA CTD PMID:23649840 Prnp Rat ethylbenzene increases expression ISO PRNP (Homo sapiens) 6480464 ethylbenzene results in increased expression of PRNP mRNA CTD PMID:20359517 Prnp Rat ethylenediaminetetraacetic acid multiple interactions ISO Prnp (Mus musculus) 6480464 Edetic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Copper] results in increased cleavage of PRNP protein] and Edetic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Iron] results in increased cleavage of PRNP protein] CTD PMID:16595185 Prnp Rat etoposide decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Etoposide CTD PMID:15386405 Prnp Rat fenthion decreases expression ISO Prnp (Mus musculus) 6480464 Fenthion results in decreased expression of PRNP mRNA CTD PMID:34813904 Prnp Rat filipin III increases secretion ISO PRNP (Homo sapiens) 6480464 Filipin results in increased secretion of PRNP protein CTD PMID:11994310 Prnp Rat filipin III multiple interactions ISO Prnp (Mus musculus) 6480464 [Copper co-treated with Filipin] results in increased cleavage of PRNP protein and Filipin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] CTD PMID:11994310 and PMID:19597535 Prnp Rat filipin III multiple interactions ISO PRNP (Homo sapiens) 6480464 Filipin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] CTD PMID:11994310 Prnp Rat filipin III decreases expression ISO Prnp (Mus musculus) 6480464 Filipin results in decreased expression of PRNP protein alternative form CTD PMID:11994310 Prnp Rat filipin III increases secretion ISO Prnp (Mus musculus) 6480464 Filipin results in increased secretion of PRNP protein CTD PMID:11994310 Prnp Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of PRNP mRNA CTD PMID:24793618 Prnp Rat folic acid multiple interactions ISO Prnp (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRNP mRNA CTD PMID:22206623 Prnp Rat formaldehyde increases expression ISO PRNP (Homo sapiens) 6480464 Formaldehyde results in increased expression of PRNP mRNA CTD PMID:23649840 Prnp Rat furan increases expression EXP 6480464 furan results in increased expression of PRNP mRNA CTD PMID:27387713 Prnp Rat genistein increases expression EXP 6480464 Genistein results in increased expression of PRNP mRNA CTD PMID:12075121 Prnp Rat genistein decreases expression ISO Prnp (Mus musculus) 6480464 Genistein results in decreased expression of PRNP mRNA CTD PMID:24967385 Prnp Rat genistein increases expression ISO PRNP (Homo sapiens) 6480464 Genistein results in increased expression of PRNP mRNA CTD PMID:18444173 Prnp Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of PRNP mRNA CTD PMID:22061828 Prnp Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PRNP mRNA CTD PMID:33387578 Prnp Rat glucose multiple interactions ISO PRNP (Homo sapiens) 6480464 [PRNP protein results in increased expression of SLC2A1 protein] which results in increased uptake of Glucose CTD PMID:21265952 Prnp Rat glutathione multiple interactions ISO Prnp (Mus musculus) 6480464 PRNP protein inhibits the reaction [manganese chloride results in decreased abundance of Glutathione] CTD PMID:17483122 Prnp Rat glyphosate decreases methylation EXP 6480464 Glyphosate results in decreased methylation of PRNP gene CTD PMID:31011160 Prnp Rat graphene oxide decreases expression ISO PRNP (Homo sapiens) 6480464 graphene oxide results in decreased expression of PRNP protein CTD PMID:33219560 Prnp Rat GW 1929 multiple interactions ISO PRNP (Homo sapiens) 6480464 GW 1929 inhibits the reaction [Melatonin results in increased expression of PRNP protein] and GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PRNP protein] CTD PMID:29734669 Prnp Rat heparan sulfate affects binding ISO Prnp (Mus musculus) 6480464 PRNP protein modified form binds to Heparitin Sulfate metabolite CTD PMID:18717736 Prnp Rat hydrogen peroxide increases expression ISO PRNP (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of PRNP mRNA CTD PMID:12419474 Prnp Rat hydrogen peroxide decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:17483122 Prnp Rat hydrogen peroxide increases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in increased susceptibility to Hydrogen Peroxide CTD PMID:12500977 Prnp Rat hydrogen peroxide multiple interactions ISO Prnp (Mus musculus) 6480464 [[Hydrogen Peroxide co-treated with Copper] results in increased cleavage of PRNP protein] promotes the reaction [PRNP protein binds to PRNP protein] more ... CTD PMID:16595185 Prnp Rat indoxyl sulfate multiple interactions ISO PRNP (Homo sapiens) 6480464 PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]] more ... CTD PMID:29734669 Prnp Rat inulin multiple interactions ISO Prnp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PRNP mRNA CTD PMID:36331819 Prnp Rat iron atom multiple interactions ISO Prnp (Mus musculus) 6480464 [Hydrogen Peroxide co-treated with Iron] results in increased cleavage of PRNP protein more ... CTD PMID:16595185 and PMID:23478311 Prnp Rat iron atom decreases abundance ISO Prnp (Mus musculus) 6480464 PRNP gene mutant form results in decreased abundance of Iron CTD PMID:23478311 Prnp Rat iron(0) decreases abundance ISO Prnp (Mus musculus) 6480464 PRNP gene mutant form results in decreased abundance of Iron CTD PMID:23478311 Prnp Rat iron(0) multiple interactions ISO Prnp (Mus musculus) 6480464 [Hydrogen Peroxide co-treated with Iron] results in increased cleavage of PRNP protein more ... CTD PMID:16595185 and PMID:23478311 Prnp Rat lead diacetate increases expression ISO Prnp (Mus musculus) 6480464 lead acetate results in increased expression of PRNP mRNA CTD PMID:29746905 Prnp Rat lead tetraacetate decreases expression ISO Prnp (Mus musculus) 6480464 lead tetraacetate results in decreased expression of PRNP mRNA CTD PMID:20865013 Prnp Rat lead(0) affects expression ISO PRNP (Homo sapiens) 6480464 Lead affects the expression of PRNP mRNA CTD PMID:28903495 Prnp Rat lipopolysaccharide increases expression ISO Prnp (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of PRNP mRNA CTD PMID:19339665 Prnp Rat lipopolysaccharide multiple interactions ISO Prnp (Mus musculus) 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PRNP mRNA] CTD PMID:19339665 Prnp Rat luzindole multiple interactions ISO PRNP (Homo sapiens) 6480464 luzindole inhibits the reaction [Melatonin results in increased expression of PRNP protein] and luzindole inhibits the reaction [Pioglitazone results in increased expression of PRNP protein] CTD PMID:29734669 Prnp Rat manganese atom increases stability ISO Prnp (Mus musculus) 6480464 Manganese results in increased stability of PRNP protein CTD PMID:20176619 Prnp Rat manganese atom affects binding ISO Prnp (Mus musculus) 6480464 PRNP protein binds to Manganese CTD PMID:16595185 Prnp Rat manganese atom multiple interactions ISO Prnp (Mus musculus) 6480464 [[PRNP protein binds to Manganese] which co-treated with Hydrogen Peroxide] results in increased cleavage of [PRNP protein binds to PRNP protein] more ... CTD PMID:16595185 Prnp Rat manganese(0) increases stability ISO Prnp (Mus musculus) 6480464 Manganese results in increased stability of PRNP protein CTD PMID:20176619 Prnp Rat manganese(0) affects binding ISO Prnp (Mus musculus) 6480464 PRNP protein binds to Manganese CTD PMID:16595185 Prnp Rat manganese(0) multiple interactions ISO Prnp (Mus musculus) 6480464 [[PRNP protein binds to Manganese] which co-treated with Hydrogen Peroxide] results in increased cleavage of [PRNP protein binds to PRNP protein] more ... CTD PMID:16595185 Prnp Rat manganese(II) chloride multiple interactions ISO Prnp (Mus musculus) 6480464 PRNP protein inhibits the reaction [manganese chloride results in decreased abundance of Glutathione] more ... CTD PMID:17483122 Prnp Rat manganese(II) chloride decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to manganese chloride CTD PMID:17483122 Prnp Rat melatonin increases expression ISO PRNP (Homo sapiens) 6480464 Melatonin results in increased expression of PRNP protein CTD PMID:29734669 Prnp Rat melatonin multiple interactions ISO PRNP (Homo sapiens) 6480464 GW 1929 inhibits the reaction [Melatonin results in increased expression of PRNP protein] more ... CTD PMID:29734669 Prnp Rat mercury dibromide increases expression ISO PRNP (Homo sapiens) 6480464 mercuric bromide results in increased expression of PRNP mRNA CTD PMID:26272509 Prnp Rat mercury dibromide multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRNP mRNA CTD PMID:27188386 Prnp Rat metam multiple interactions ISO Prnp (Mus musculus) 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PRNP mRNA] CTD PMID:19339665 Prnp Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of PRNP mRNA CTD PMID:30467583 Prnp Rat methotrexate decreases expression ISO PRNP (Homo sapiens) 6480464 Methotrexate results in decreased expression of PRNP mRNA CTD PMID:17400583 Prnp Rat methyl methanesulfonate increases expression ISO PRNP (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of PRNP mRNA CTD PMID:23649840 Prnp Rat methylmercury chloride increases expression ISO PRNP (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of PRNP mRNA CTD PMID:28001369 and PMID:29581082 Prnp Rat methylseleninic acid increases expression ISO PRNP (Homo sapiens) 6480464 methylselenic acid results in increased expression of PRNP mRNA CTD PMID:18548127 Prnp Rat mitomycin C increases expression ISO PRNP (Homo sapiens) 6480464 Mitomycin results in increased expression of PRNP mRNA CTD PMID:12760830 Prnp Rat mono(2-ethylhexyl) phthalate increases expression ISO PRNP (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of PRNP mRNA CTD PMID:23360888 Prnp Rat N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRNP mRNA CTD PMID:28659758 Prnp Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of PRNP mRNA CTD PMID:19638242 Prnp Rat N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of PRNP mRNA CTD PMID:25380136 Prnp Rat NADP zwitterion multiple interactions ISO Prnp (Mus musculus) 6480464 [NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein] CTD PMID:16990274 Prnp Rat NADP zwitterion multiple interactions ISO PRNP (Homo sapiens) 6480464 [Copper co-treated with NADP] promotes the reaction [PRNP protein binds to PRNP protein] and [Copper co-treated with NADP] results in increased susceptibility to [PRNP protein binds to PRNP protein] CTD PMID:19149680 Prnp Rat NADP(+) multiple interactions ISO Prnp (Mus musculus) 6480464 [NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein] CTD PMID:16990274 Prnp Rat NADP(+) multiple interactions ISO PRNP (Homo sapiens) 6480464 [Copper co-treated with NADP] promotes the reaction [PRNP protein binds to PRNP protein] and [Copper co-treated with NADP] results in increased susceptibility to [PRNP protein binds to PRNP protein] CTD PMID:19149680 Prnp Rat nickel atom affects binding ISO PRNP (Homo sapiens) 6480464 Nickel binds to PRNP protein CTD PMID:17126907 Prnp Rat nickel atom multiple interactions ISO Prnp (Mus musculus) 6480464 Nickel inhibits the reaction [PRNP protein binds to PRNP protein] CTD PMID:16595185 Prnp Rat nickel sulfate decreases expression ISO PRNP (Homo sapiens) 6480464 nickel sulfate results in decreased expression of PRNP mRNA CTD PMID:22714537 Prnp Rat nitroprusside multiple interactions ISO PRNP (Homo sapiens) 6480464 [Nitroprusside results in increased abundance of nitrosonium ion] which results in increased expression of PRNP mRNA CTD PMID:12393473 Prnp Rat nystatin multiple interactions ISO PRNP (Homo sapiens) 6480464 Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] CTD PMID:11994310 Prnp Rat nystatin multiple interactions ISO Prnp (Mus musculus) 6480464 Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] CTD PMID:11994310 Prnp Rat o-xylene increases expression ISO PRNP (Homo sapiens) 6480464 2-xylene results in increased expression of PRNP mRNA CTD PMID:20359517 Prnp Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of PRNP mRNA CTD PMID:25729387 Prnp Rat oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of PRNP mRNA CTD PMID:25729387 Prnp Rat ozone multiple interactions ISO PRNP (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of PRNP mRNA CTD PMID:35430440 Prnp Rat panobinostat multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRNP mRNA CTD PMID:27188386 Prnp Rat panobinostat increases expression ISO PRNP (Homo sapiens) 6480464 panobinostat results in increased expression of PRNP mRNA CTD PMID:26272509 Prnp Rat paracetamol increases expression ISO PRNP (Homo sapiens) 6480464 Acetaminophen results in increased expression of PRNP mRNA CTD PMID:21420995 more ... Prnp Rat paraquat decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Paraquat CTD PMID:15451062 and PMID:17896796 Prnp Rat parathion decreases expression ISO Prnp (Mus musculus) 6480464 Parathion results in decreased expression of PRNP mRNA CTD PMID:34813904 Prnp Rat perfluorohexanesulfonic acid increases expression ISO Prnp (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of PRNP mRNA CTD PMID:37995155 Prnp Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Prnp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PRNP mRNA more ... CTD PMID:36331819 Prnp Rat perfluorooctanoic acid increases expression ISO PRNP (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of PRNP mRNA and perfluorooctanoic acid results in increased expression of PRNP protein CTD PMID:25868421 and PMID:26879310 Prnp Rat permethrin multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRNP mRNA CTD PMID:28659758 Prnp Rat phenylmercury acetate increases expression ISO PRNP (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of PRNP mRNA CTD PMID:26272509 Prnp Rat phenylmercury acetate multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRNP mRNA CTD PMID:27188386 Prnp Rat pioglitazone multiple interactions ISO PRNP (Homo sapiens) 6480464 GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PRNP protein] more ... CTD PMID:29734669 Prnp Rat pioglitazone increases expression ISO PRNP (Homo sapiens) 6480464 Pioglitazone results in increased expression of PRNP protein CTD PMID:29734669 Prnp Rat pirinixic acid decreases expression ISO Prnp (Mus musculus) 6480464 pirinixic acid results in decreased expression of PRNP mRNA CTD PMID:17426115 and PMID:23811191 Prnp Rat progesterone increases expression ISO PRNP (Homo sapiens) 6480464 Progesterone results in increased expression of PRNP mRNA CTD PMID:18037150 Prnp Rat Pyridostigmine bromide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRNP mRNA CTD PMID:28659758 Prnp Rat reactive oxygen species multiple interactions ISO PRNP (Homo sapiens) 6480464 [[[Copper binds to PRNP protein] which results in increased reduction of Copper] which results in increased abundance of Reactive Oxygen Species] which results in increased cleavage of PRNP protein and [[Copper binds to PRNP protein] which results in increased reduction of Copper] which results in increased abundance of Reactive Oxygen Species CTD PMID:19697239 Prnp Rat reactive oxygen species multiple interactions ISO Prnp (Mus musculus) 6480464 PRNP protein inhibits the reaction [manganese chloride results in increased chemical synthesis of Reactive Oxygen Species] CTD PMID:17483122 Prnp Rat resveratrol multiple interactions ISO PRNP (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of PRNP mRNA CTD PMID:23557933 Prnp Rat SB 431542 multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Prnp Rat silicon dioxide increases expression ISO Prnp (Mus musculus) 6480464 Silicon Dioxide results in increased expression of PRNP mRNA CTD PMID:38403151 Prnp Rat silver atom affects expression ISO Prnp (Mus musculus) 6480464 Silver affects the expression of PRNP mRNA CTD PMID:19429238 Prnp Rat silver atom increases expression ISO PRNP (Homo sapiens) 6480464 Silver results in increased expression of PRNP mRNA CTD PMID:26551752 Prnp Rat silver(0) affects expression ISO Prnp (Mus musculus) 6480464 Silver affects the expression of PRNP mRNA CTD PMID:19429238 Prnp Rat silver(0) increases expression ISO PRNP (Homo sapiens) 6480464 Silver results in increased expression of PRNP mRNA CTD PMID:26551752 Prnp Rat sodium arsenite decreases expression ISO PRNP (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PRNP mRNA CTD PMID:22714537 Prnp Rat sodium arsenite affects expression ISO PRNP (Homo sapiens) 6480464 sodium arsenite affects the expression of PRNP mRNA CTD PMID:29319823 Prnp Rat sodium arsenite increases expression ISO PRNP (Homo sapiens) 6480464 sodium arsenite results in increased expression of PRNP mRNA CTD PMID:12760830 more ... Prnp Rat tamibarotene affects expression ISO PRNP (Homo sapiens) 6480464 tamibarotene affects the expression of PRNP mRNA CTD PMID:15498508 Prnp Rat tert-butyl hydroperoxide increases expression ISO PRNP (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of PRNP mRNA CTD PMID:15336504 Prnp Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PRNP mRNA] CTD PMID:31150632 Prnp Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PRNP mRNA CTD PMID:31150632 Prnp Rat tetracycline affects binding ISO PRNP (Homo sapiens) 6480464 Tetracycline binds to PRNP protein CTD PMID:10903871 Prnp Rat tetracycline multiple interactions ISO PRNP (Homo sapiens) 6480464 Tetracycline inhibits the reaction [PRNP protein binds to PRNP protein] CTD PMID:10903871 Prnp Rat thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of PRNP protein CTD PMID:35544339 Prnp Rat thiamethoxam increases expression ISO Prnp (Mus musculus) 6480464 Thiamethoxam results in increased expression of PRNP mRNA CTD PMID:33533595 Prnp Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of PRNP mRNA CTD PMID:23411599 and PMID:34492290 Prnp Rat titanium dioxide decreases methylation ISO Prnp (Mus musculus) 6480464 titanium dioxide results in decreased methylation of PRNP gene and titanium dioxide results in decreased methylation of PRNP promoter CTD PMID:35295148 Prnp Rat toluene increases expression ISO PRNP (Homo sapiens) 6480464 Toluene results in increased expression of PRNP mRNA CTD PMID:20359517 Prnp Rat topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of PRNP mRNA CTD PMID:25729387 Prnp Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of PRNP mRNA CTD PMID:25729387 Prnp Rat trichloroethene decreases expression ISO Prnp (Mus musculus) 6480464 Trichloroethylene results in decreased expression of PRNP mRNA CTD PMID:19448997 Prnp Rat trichloroethene increases expression ISO PRNP (Homo sapiens) 6480464 Trichloroethylene results in increased expression of PRNP mRNA CTD PMID:20359517 Prnp Rat trichostatin A increases expression ISO PRNP (Homo sapiens) 6480464 trichostatin A results in increased expression of PRNP mRNA CTD PMID:24935251 and PMID:26272509 Prnp Rat trichostatin A multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRNP mRNA CTD PMID:27188386 Prnp Rat tunicamycin increases expression ISO PRNP (Homo sapiens) 6480464 Tunicamycin results in increased expression of PRNP mRNA CTD PMID:22378314 Prnp Rat urethane increases expression ISO PRNP (Homo sapiens) 6480464 Urethane results in increased expression of PRNP mRNA CTD PMID:28818685 Prnp Rat ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of PRNP mRNA CTD PMID:15885361 Prnp Rat valproic acid multiple interactions ISO PRNP (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRNP mRNA CTD PMID:27188386 Prnp Rat valproic acid increases expression ISO PRNP (Homo sapiens) 6480464 Valproic Acid results in increased expression of PRNP mRNA CTD PMID:19101580 more ... Prnp Rat vincristine decreases response to substance ISO PRNP (Homo sapiens) 6480464 PRNP protein results in decreased susceptibility to Vincristine CTD PMID:15386405 Prnp Rat zinc atom affects localization ISO Prnp (Mus musculus) 6480464 PRNP protein affects the localization of Zinc CTD PMID:19486831 Prnp Rat zinc atom decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Zinc CTD PMID:19486831 Prnp Rat zinc oxide increases expression ISO PRNP (Homo sapiens) 6480464 Zinc Oxide results in increased expression of PRNP mRNA CTD PMID:19755143 Prnp Rat zinc(0) affects localization ISO Prnp (Mus musculus) 6480464 PRNP protein affects the localization of Zinc CTD PMID:19486831 Prnp Rat zinc(0) decreases response to substance ISO Prnp (Mus musculus) 6480464 PRNP protein results in decreased susceptibility to Zinc CTD PMID:19486831