Gene: Kcnk2 (potassium two pore domain channel subfamily K member 2) Rattus norvegicus
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Symbol: Kcnk2
Name: potassium two pore domain channel subfamily K member 2
Description: ENCODES a protein that exhibits outward rectifier potassium channel activity; potassium channel inhibitor activity; potassium ion leak channel activity; INVOLVED IN cardiac ventricle development; cellular response to hypoxia; cochlea development; ASSOCIATED WITH brain ischemia; congestive heart failure; Inflammation; FOUND IN apical plasma membrane; astrocyte projection; axon; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil
AGR Description: Exhibits outward rectifier potassium channel activity, potassium channel inhibitor activity, and potassium ion leak channel activity; involved in several processes, including animal organ development, cellular response to hypoxia, and memory; localizes to several cellular components, including the apical plasma membrane, astrocyte projection, and intracellular membrane-bounded organelle; used to study transient cerebral ischemia; biomarker of brain ischemia, congestive heart failure, myocardial infarction, and transient cerebral ischemia; orthologous to human KCNK2 (potassium two pore domain channel subfamily K member 2).
Merged Description: Exhibits outward rectifier potassium channel activity, potassium channel inhibitor activity, and potassium ion leak channel activity; involved in several processes, including animal organ development, cellular response to hypoxia, and memory; localizes to several cellular components, including the apical plasma membrane, astrocyte projection, and intracellular membrane-bounded organelle; used to study transient cerebral ischemia; biomarker of brain ischemia, congestive heart failure, myocardial infarction, and transient cerebral ischemia; orthologous to human KCNK2 (potassium two pore domain channel subfamily K member 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arachidonic acid sensitive tandem pore domain potassium channel; ion transport membrane protein; outward rectifying potassium channel protein TREK-1; potassium channel subfamily K member 2; potassium channel, subfamily K, member 2; potassium channel, two pore domain subfamily K, member 2; rTREK1d; stretch-activated potassium channel TREK-1; tandem-pore-domain potassium channel TREK-1; Trek-1; TREK-1 K(+) channel subunit; two pore domain potassium channel TREK-1; two pore potassium channel TPKC1
Orthologs:
Homo sapiens (human) : KCNK2 (potassium two pore domain channel subfamily K member 2)  HGNC  Alliance
Mus musculus (house mouse) : Kcnk2 (potassium channel, subfamily K, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kcnk2 (potassium two pore domain channel subfamily K member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KCNK2 (potassium two pore domain channel subfamily K member 2)
Canis lupus familiaris (dog) : KCNK2 (potassium two pore domain channel subfamily K member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kcnk2 (potassium two pore domain channel subfamily K member 2)
Sus scrofa (pig) : KCNK2 (potassium two pore domain channel subfamily K member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013107,690,111 - 107,886,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013112,318,467 - 112,512,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413105,376,001 - 105,574,238 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113105,665,411 - 105,705,891 (-)NCBI
Celera13100,255,787 - 100,450,992 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

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Nomenclature History
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More on Kcnk2
Alliance Gene
NCBI Gene
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RGD Object Information
RGD ID: 621448
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.