Xrcc2 (X-ray repair cross complementing 2) - Rat Genome Database

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Gene: Xrcc2 (X-ray repair cross complementing 2) Rattus norvegicus
Analyze
Symbol: Xrcc2
Name: X-ray repair cross complementing 2
RGD ID: 1564823
Description: Predicted to enable ATP binding activity and ATP-dependent activity, acting on DNA. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in DNA recombination; centrosome cycle; and mitotic cell cycle. Predicted to act upstream of or within several processes, including chordate embryonic development; regulation of apoptotic process; and response to X-ray. Predicted to be located in nucleoplasm. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Predicted to be active in centrosome and replication fork. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group U; pancreatic cancer; primary ovarian insufficiency 17; and spermatogenic failure 50. Orthologous to human XRCC2 (X-ray repair cross complementing 2); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DNA repair protein XRCC2; LOC102553514; LOC499966; RGD1564823; similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2); uncharacterized LOC102553514; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross complementing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.249,423,873 - 9,502,980 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl49,423,898 - 9,442,482 (+)Ensembl
Rnor_6.045,842,013 - 5,860,516 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl45,841,998 - 5,860,527 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.045,865,989 - 5,884,492 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.444,817,222 - 4,835,725 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4876,632 - 895,138 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10422536   PMID:11751635   PMID:11834724   PMID:15979950   PMID:16777961   PMID:17116431   PMID:20207730   PMID:21276791   PMID:23149936  


Genomics

Comparative Map Data
Xrcc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.249,423,873 - 9,502,980 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl49,423,898 - 9,442,482 (+)Ensembl
Rnor_6.045,842,013 - 5,860,516 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl45,841,998 - 5,860,527 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.045,865,989 - 5,884,492 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.444,817,222 - 4,835,725 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4876,632 - 895,138 (-)NCBICelera
Cytogenetic Map4q11NCBI
XRCC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387152,644,776 - 152,676,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7152,644,776 - 152,676,141 (-)EnsemblGRCh38hg38GRCh38
GRCh377152,341,861 - 152,373,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367151,974,516 - 152,004,183 (-)NCBINCBI36hg18NCBI36
Build 347151,781,236 - 151,810,898NCBI
Celera7146,907,598 - 146,937,489 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7146,154,439 - 146,184,018 (-)NCBIHuRef
CHM1_17152,351,916 - 152,381,649 (-)NCBICHM1_1
T2T-CHM13v2.07153,818,164 - 153,849,721 (-)NCBI
CRA_TCAGchr7v27151,670,667 - 151,700,330 (-)NCBI
Xrcc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39525,894,812 - 25,910,795 (-)NCBIGRCm39mm39
GRCm39 Ensembl525,894,810 - 25,910,823 (-)Ensembl
GRCm38525,689,814 - 25,705,797 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl525,689,812 - 25,705,825 (-)EnsemblGRCm38mm10GRCm38
MGSCv37525,195,632 - 25,211,615 (-)NCBIGRCm37mm9NCBIm37
MGSCv36525,199,879 - 25,215,862 (-)NCBImm8
Celera522,629,689 - 22,645,599 (-)NCBICelera
Cytogenetic Map5B1NCBI
Xrcc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554916,599,085 - 6,629,439 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554916,579,443 - 6,629,410 (-)NCBIChiLan1.0ChiLan1.0
XRCC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17156,378,685 - 156,406,516 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7156,378,685 - 156,406,516 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07144,229,031 - 144,256,854 (-)NCBIMhudiblu_PPA_v0panPan3
XRCC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11616,402,821 - 16,429,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1616,402,933 - 16,429,037 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1617,019,573 - 17,045,315 (-)NCBI
ROS_Cfam_1.01618,134,572 - 18,160,367 (-)NCBI
ROS_Cfam_1.0 Ensembl1618,134,726 - 18,160,313 (-)Ensembl
UMICH_Zoey_3.11616,507,780 - 16,533,550 (-)NCBI
UNSW_CanFamBas_1.01617,088,510 - 17,114,628 (-)NCBI
UU_Cfam_GSD_1.01617,139,622 - 17,165,358 (-)NCBI
Xrcc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051185,118,065 - 5,142,946 (+)NCBI
SpeTri2.0NW_0049365277,760,609 - 7,785,360 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XRCC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl184,808,469 - 4,835,804 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1184,808,428 - 4,834,281 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2184,937,262 - 5,312,081 (+)NCBISscrofa10.2Sscrofa10.2susScr3
XRCC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121120,795,188 - 120,827,737 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl21120,795,212 - 120,827,706 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607216,791,808 - 16,824,354 (-)NCBIVero_WHO_p1.0
Xrcc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248004,355,539 - 4,390,016 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248004,352,566 - 4,389,707 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D4Rat142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,434,008 - 9,434,224 (+)MAPPERmRatBN7.2
Rnor_6.045,852,089 - 5,852,304NCBIRnor6.0
Rnor_5.045,876,065 - 5,876,280UniSTSRnor5.0
RGSC_v3.444,827,297 - 4,827,513RGDRGSC3.4
RGSC_v3.444,827,298 - 4,827,513UniSTSRGSC3.4
RGSC_v3.144,827,297 - 4,827,513RGD
Celera4884,845 - 885,060UniSTS
RH 2.0 Map48.8RGD
SHRSP x BN Map40.0RGD
Cytogenetic Map4q11UniSTS
RH137229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,442,243 - 9,442,407 (+)MAPPERmRatBN7.2
Rnor_6.045,860,324 - 5,860,487NCBIRnor6.0
Rnor_5.045,884,300 - 5,884,463UniSTSRnor5.0
RGSC_v3.444,835,533 - 4,835,696UniSTSRGSC3.4
Celera4876,661 - 876,824UniSTS
Cytogenetic Map4q11UniSTS
RH128395  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,442,139 - 9,442,343 (+)MAPPERmRatBN7.2
Rnor_6.045,860,220 - 5,860,423NCBIRnor6.0
Rnor_5.045,884,196 - 5,884,399UniSTSRnor5.0
RGSC_v3.444,835,429 - 4,835,632UniSTSRGSC3.4
Celera4876,725 - 876,928UniSTS
Cytogenetic Map4q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:338
Count of miRNA genes:193
Interacting mature miRNAs:241
Transcripts:ENSRNOT00000010025
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 14 12 4 12 20 12 29
Low 3 37 43 29 15 29 8 11 54 23 12 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010025   ⟹   ENSRNOP00000010025
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl49,423,898 - 9,442,482 (+)Ensembl
Rnor_6.0 Ensembl45,841,998 - 5,860,527 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094249   ⟹   ENSRNOP00000096624
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl49,423,898 - 9,433,843 (+)Ensembl
RefSeq Acc Id: NM_001109215   ⟹   NP_001102685
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.249,423,933 - 9,442,436 (+)NCBI
Rnor_6.045,842,013 - 5,860,516 (+)NCBI
Rnor_5.045,865,989 - 5,884,492 (+)NCBI
RGSC_v3.444,817,222 - 4,835,725 (+)RGD
Celera4876,632 - 895,138 (-)RGD
Sequence:
RefSeq Acc Id: XM_039108055   ⟹   XP_038963983
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.249,423,911 - 9,442,499 (+)NCBI
RefSeq Acc Id: XM_039108056   ⟹   XP_038963984
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.249,423,873 - 9,502,980 (+)NCBI
RefSeq Acc Id: XM_039108057   ⟹   XP_038963985
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.249,423,882 - 9,439,259 (+)NCBI
RefSeq Acc Id: XM_039108058   ⟹   XP_038963986
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.249,423,877 - 9,490,011 (+)NCBI
RefSeq Acc Id: XR_005503281
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.249,423,880 - 9,439,257 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001102685   ⟸   NM_001109215
- UniProtKB: D3ZPC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010025   ⟸   ENSRNOT00000010025
RefSeq Acc Id: XP_038963984   ⟸   XM_039108056
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038963986   ⟸   XM_039108058
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963985   ⟸   XM_039108057
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963983   ⟸   XM_039108055
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000096624   ⟸   ENSRNOT00000094249
Protein Domains
RECA_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZPC8-F1-model_v2 AlphaFold D3ZPC8 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692777
Promoter ID:EPDNEW_R3301
Type:initiation region
Name:Xrcc2_1
Description:X-ray repair cross complementing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.045,842,033 - 5,842,093EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564823 AgrOrtholog
BioCyc Gene G2FUF-46096 BioCyc
Ensembl Genes ENSRNOG00000007493 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000010025 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010025 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb_RecA/RadB_ATP-bd UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  XRCC2 UniProtKB/TrEMBL
KEGG Report rno:499966 UniProtKB/TrEMBL
NCBI Gene 499966 ENTREZGENE
PANTHER PTHR46644 UniProtKB/TrEMBL
Pfam Rad51 UniProtKB/TrEMBL
PhenoGen Xrcc2 PhenoGen
PROSITE RECA_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt D3ZPC8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Xrcc2  X-ray repair cross complementing 2  LOC102553514  uncharacterized LOC102553514  Data Merged 737654 PROVISIONAL
2016-06-08 Xrcc2  X-ray repair cross complementing 2  Xrcc2  X-ray repair complementing defective repair in Chinese hamster cells 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102553514  uncharacterized LOC102553514      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-06 Xrcc2  X-ray repair complementing defective repair in Chinese hamster cells 2  RGD1564823_predicted  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564823_predicted  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2) (predicted)  LOC499966  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499966  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2)      Symbol and Name status set to provisional 70820 PROVISIONAL