Gene: Sohlh1 (spermatogenesis and oogenesis specific basic helix-loop-helix 1) Rattus norvegicus
Analyze
Symbol: Sohlh1
Name: spermatogenesis and oogenesis specific basic helix-loop-helix 1
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cell differentiation (ortholog); oocyte differentiation (ortholog); oogenesis (ortholog); ASSOCIATED WITH hypogonadism (ortholog); ovarian dysgenesis 5 (ortholog); Spermatogenic Failure 32 (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); all-trans-retinoic acid (ortholog)
AGR Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II regulatory region sequence-specific DNA binding activity, and protein dimerization activity; predicted to be involved in gamete generation, ovarian follicle development, and positive regulation of transcription by RNA polymerase II; predicted to localize to the cytoplasm and nucleus; orthologous to human SOHLH1 (spermatogenesis and oogenesis specific basic helix-loop-helix 1).
Merged Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II regulatory region sequence-specific DNA binding activity, and protein dimerization activity; predicted to be involved in gamete generation, ovarian follicle development, and positive regulation of transcription by RNA polymerase II; predicted to localize to the cytoplasm and nucleus; orthologous to human SOHLH1 (spermatogenesis and oogenesis specific basic helix-loop-helix 1); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); all-trans-retinoic acid (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC362085; RGD1564440; similar to helix-loop-helix protein NOHLH; spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.033,290,766 - 3,295,226 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.038,653,008 - 8,657,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,015,651 - 4,019,668 (-)NCBIRGSC3.4rn4RGSC3.4
Celera33,486,441 - 3,490,458 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sohlh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564440
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.