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Gene: Atrx (ATRX, chromatin remodeler) Rattus norvegicus
Symbol: Atrx
Name: ATRX, chromatin remodeler
RGD ID: 619795
Description: Predicted to have several functions, including DNA translocase activity; chromo shadow domain binding activity; and methylated histone binding activity. Predicted to be involved in several processes, including male gonad development; regulation of chromosome organization; and regulation of telomeric RNA transcription from RNA pol II promoter. Localizes to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in alpha thalassemia-X-linked intellectual disability syndrome and malignant glioma. Orthologous to human ATRX (ATRX chromatin remodeler); INTERACTS WITH (+)-pilocarpine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha thalassemia/mental retardation syndrome X-linked; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae); alpha thalassemia/mental retardation syndrome X-linked homolog; alpha thalassemia/mental retardation syndrome X-linked homolog (human); ATP-dependent helicase ATRX; helicase II; LOW QUALITY PROTEIN: transcriptional regulator ATRX; pABP-2; transcriptional regulator ATRX; X-linked nuclear protein; Xnp
Homo sapiens (human) : ATRX (ATRX chromatin remodeler)  HGNC  Alliance
Mus musculus (house mouse) : Atrx (ATRX, chromatin remodeler)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atrx (ATRX chromatin remodeler)
Pan paniscus (bonobo/pygmy chimpanzee) : ATRX (ATRX chromatin remodeler)
Canis lupus familiaris (dog) : ATRX (ATRX chromatin remodeler)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atrx (ATRX chromatin remodeler)
Sus scrofa (pig) : ATRX (ATRX chromatin remodeler)
Chlorocebus sabaeus (African green monkey) : ATRX (ATRX chromatin remodeler)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X76,820,110 - 76,979,155 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX76,692,970 - 76,708,878 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX76,820,329 - 76,979,115 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X77,469,497 - 77,515,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X55,943,493 - 56,101,756 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X93,903,794 - 94,051,337 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X94,034,366 - 94,057,029 (-)NCBI
CeleraX72,164,814 - 72,309,854 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atrx
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619795
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.