(+)-taxifolin increases expression ISO GDF15 (Homo sapiens) 6480464 taxifolin results in increased expression of GDF15 mRNA CTD PMID:17541156 (-)-demecolcine increases expression ISO GDF15 (Homo sapiens) 6480464 Demecolcine results in increased expression of GDF15 mRNA CTD PMID:23649840 (1->4)-beta-D-glucan multiple interactions ISO Gdf15 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GDF15 mRNA CTD PMID:36331819 (S)-colchicine decreases expression ISO GDF15 (Homo sapiens) 6480464 Colchicine results in decreased expression of GDF15 mRNA CTD PMID:24211769 1,1-dichloroethene increases expression ISO Gdf15 (Mus musculus) 6480464 vinylidene chloride results in increased expression of GDF15 mRNA CTD PMID:26682919 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of GDF15 mRNA CTD PMID:27840820 and PMID:32387197 1,2-dimethylhydrazine increases expression ISO Gdf15 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of GDF15 mRNA CTD PMID:22206623 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO GDF15 (Homo sapiens) 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] more ... CTD PMID:23996089 17beta-estradiol increases expression ISO Gdf15 (Mus musculus) 6480464 Estradiol results in increased expression of GDF15 mRNA CTD PMID:25210133 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GDF15 mRNA CTD PMID:31119341 17beta-estradiol increases expression ISO GDF15 (Homo sapiens) 6480464 Estradiol results in increased expression of GDF15 mRNA CTD PMID:19619570 more ... 17beta-estradiol decreases expression ISO GDF15 (Homo sapiens) 6480464 Estradiol results in decreased expression of GDF15 mRNA CTD PMID:19167446 17beta-estradiol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA more ... CTD PMID:19619570 more ... 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO GDF15 (Homo sapiens) 6480464 Metribolone results in increased expression of GDF15 mRNA CTD PMID:17010196 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO GDF15 (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of GDF15 mRNA CTD PMID:16523695 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO GDF15 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,2',5,5'-tetrachlorobiphenyl increases expression ISO GDF15 (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA more ... CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO GDF15 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of GDF15 mRNA CTD PMID:36370075 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO GDF15 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gdf15 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA CTD PMID:21215274 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO GDF15 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA CTD PMID:22298810 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO GDF15 (Homo sapiens) 6480464 2 more ... CTD PMID:26705709 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of GDF15 mRNA CTD PMID:21346803 2,6-dichloroindophenol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [2 and 6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA CTD PMID:21034357 2-acetamidofluorene increases expression ISO Gdf15 (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of GDF15 mRNA CTD PMID:21607683 2-butoxyethanol increases expression ISO Gdf15 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of GDF15 mRNA CTD PMID:19812364 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of GDF15 mRNA CTD PMID:14600272 more ... 2-palmitoylglycerol increases expression ISO GDF15 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of GDF15 mRNA CTD PMID:37199045 3,3',4,4',5-pentachlorobiphenyl increases expression ISO GDF15 (Homo sapiens) 6480464 3 more ... CTD PMID:19692669 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:32119087 3,3',4,4'-tetrachlorobiphenyl affects expression ISO GDF15 (Homo sapiens) 6480464 3 more ... CTD PMID:20638727 3,3',5,5'-tetrabromobisphenol A increases expression ISO GDF15 (Homo sapiens) 6480464 tetrabromobisphenol A results in increased expression of GDF15 protein CTD PMID:31675489 3,3',5,5'-tetrabromobisphenol A multiple interactions ISO GDF15 (Homo sapiens) 6480464 [PPARG protein results in increased susceptibility to tetrabromobisphenol A] which results in increased expression of GDF15 mRNA CTD PMID:35734227 3,3'-diindolylmethane increases expression ISO GDF15 (Homo sapiens) 6480464 3 and 3'-diindolylmethane results in increased expression of GDF15 mRNA CTD PMID:15670751 3,4-dichloroaniline increases expression EXP 6480464 3 and 4-dichloroaniline results in increased expression of GDF15 mRNA CTD PMID:24172598 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO GDF15 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol affects methylation ISO Gdf15 (Mus musculus) 6480464 bisphenol S affects the methylation of GDF15 gene CTD PMID:31683443 4,4'-sulfonyldiphenol decreases expression ISO Gdf15 (Mus musculus) 6480464 bisphenol S results in decreased expression of GDF15 mRNA CTD PMID:33297965 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GDF15 mRNA CTD PMID:14600272 more ... 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 Am 580 results in increased expression of GDF15 mRNA CTD PMID:16982809 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of GDF15 mRNA CTD PMID:21346803 4-Hydroxybenzophenone increases expression ISO Gdf15 (Mus musculus) 6480464 4-hydroxybenzophenone results in increased expression of GDF15 mRNA CTD PMID:35476924 4-hydroxyphenyl retinamide increases expression ISO GDF15 (Homo sapiens) 6480464 Fenretinide results in increased expression of GDF15 mRNA and Fenretinide results in increased expression of GDF15 protein CTD PMID:15958647 and PMID:16671099 4-hydroxyphenyl retinamide increases expression ISO Gdf15 (Mus musculus) 6480464 Fenretinide results in increased expression of GDF15 mRNA CTD PMID:28973697 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO GDF15 (Homo sapiens) 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] more ... CTD PMID:23996089 5-aza-2'-deoxycytidine affects expression ISO GDF15 (Homo sapiens) 6480464 Decitabine affects the expression of GDF15 mRNA CTD PMID:17145863 and PMID:23300844 5-aza-2'-deoxycytidine multiple interactions ISO GDF15 (Homo sapiens) 6480464 Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 mRNA] and Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 protein] CTD PMID:18801729 5-aza-2'-deoxycytidine increases expression ISO Gdf15 (Mus musculus) 6480464 Decitabine results in increased expression of GDF15 mRNA CTD PMID:27915011 5-bromo-2'-deoxyuridine multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 5-fluorouracil increases expression ISO GDF15 (Homo sapiens) 6480464 Fluorouracil results in increased expression of GDF15 mRNA and Fluorouracil results in increased expression of GDF15 protein CTD PMID:14665630 more ... 5-fluorouracil multiple interactions ISO GDF15 (Homo sapiens) 6480464 TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA] CTD PMID:15016801 7,12-dimethyltetraphene increases expression ISO Gdf15 (Mus musculus) 6480464 9 more ... CTD PMID:32553695 8-Br-cAMP increases expression ISO GDF15 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF15 mRNA CTD PMID:22079614 9-cis-retinoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 Alitretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 [6]-Shogaol increases expression ISO GDF15 (Homo sapiens) 6480464 shogaol results in increased expression of GDF15 mRNA CTD PMID:25148906 aceclofenac increases expression ISO GDF15 (Homo sapiens) 6480464 aceclofenac results in increased expression of GDF15 protein CTD PMID:15555568 aceclofenac increases expression ISO Gdf15 (Mus musculus) 6480464 aceclofenac results in increased expression of GDF15 mRNA CTD PMID:18076062 acetamide increases expression EXP 6480464 acetamide results in increased expression of GDF15 mRNA CTD PMID:31881176 acetylsalicylic acid increases expression ISO GDF15 (Homo sapiens) 6480464 Aspirin results in increased expression of GDF15 mRNA and Aspirin results in increased expression of GDF15 protein CTD PMID:14976132 and PMID:15180942 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of GDF15 mRNA CTD PMID:28959563 acrylamide increases expression ISO GDF15 (Homo sapiens) 6480464 Acrylamide results in increased expression of GDF15 mRNA CTD PMID:32763439 and PMID:35690182 acrylamide increases expression ISO Gdf15 (Mus musculus) 6480464 Acrylamide results in increased expression of GDF15 mRNA CTD PMID:30807115 actinomycin D multiple interactions ISO GDF15 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [resveratrol results in increased expression of GDF15 mRNA] CTD PMID:17257620 adefovir pivoxil increases expression ISO GDF15 (Homo sapiens) 6480464 adefovir dipivoxil results in increased expression of GDF15 mRNA CTD PMID:25596134 adenine decreases expression ISO GDF15 (Homo sapiens) 6480464 Adenine results in decreased expression of GDF15 mRNA CTD PMID:24211769 aflatoxin B1 affects expression ISO GDF15 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of GDF15 protein CTD PMID:20106945 aflatoxin B1 increases expression ISO GDF15 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of GDF15 mRNA CTD PMID:21632981 more ... aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of GDF15 mRNA CTD PMID:14600272 more ... all-trans-4-oxoretinoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 4-oxoretinoic acid results in increased expression of GDF15 mRNA CTD PMID:15982314 all-trans-retinoic acid decreases expression ISO GDF15 (Homo sapiens) 6480464 Tretinoin results in decreased expression of GDF15 mRNA CTD PMID:17045167 all-trans-retinoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 Tretinoin metabolite results in increased expression of GDF15 mRNA and Tretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 and PMID:23830798 amiodarone increases expression ISO GDF15 (Homo sapiens) 6480464 Amiodarone results in increased expression of GDF15 mRNA CTD PMID:19774075 and PMID:36586010 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GDF15 mRNA CTD PMID:16483693 amphibole asbestos affects expression ISO GDF15 (Homo sapiens) 6480464 Asbestos and Amphibole affects the expression of GDF15 protein CTD PMID:20855422 amphotericin B increases expression ISO GDF15 (Homo sapiens) 6480464 Amphotericin B analog results in increased expression of GDF15 mRNA and Amphotericin B results in increased expression of GDF15 mRNA CTD PMID:28534445 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO GDF15 (Homo sapiens) 6480464 pyrazolanthrone promotes the reaction [silybin results in increased expression of GDF15 protein] CTD PMID:24440808 antimycin A increases expression ISO GDF15 (Homo sapiens) 6480464 Antimycin A results in increased expression of GDF15 mRNA CTD PMID:33512557 arecoline increases expression ISO GDF15 (Homo sapiens) 6480464 Arecoline results in increased expression of GDF15 mRNA CTD PMID:17682004 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of GDF15 mRNA CTD PMID:23912714 aristolochic acid A increases expression ISO GDF15 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of GDF15 mRNA CTD PMID:33212167 arsane decreases expression ISO GDF15 (Homo sapiens) 6480464 Arsenic results in decreased expression of GDF15 mRNA CTD PMID:12773770 arsenic atom decreases expression ISO GDF15 (Homo sapiens) 6480464 Arsenic results in decreased expression of GDF15 mRNA CTD PMID:12773770 arsenite(3-) multiple interactions ISO GDF15 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to GDF15 mRNA] CTD PMID:32406909 arsenous acid increases expression ISO GDF15 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of GDF15 mRNA CTD PMID:19036111 more ... atrazine increases expression ISO GDF15 (Homo sapiens) 6480464 Atrazine results in increased expression of GDF15 mRNA CTD PMID:22378314 Aurin increases expression ISO GDF15 (Homo sapiens) 6480464 aurin results in increased expression of GDF15 mRNA CTD PMID:25477506 azathioprine increases expression ISO GDF15 (Homo sapiens) 6480464 Azathioprine results in increased expression of GDF15 mRNA CTD PMID:22623647 azoxystrobin multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 azoxystrobin increases expression ISO GDF15 (Homo sapiens) 6480464 azoxystrobin results in increased expression of GDF15 mRNA CTD PMID:33512557 benzo[a]pyrene increases expression ISO Gdf15 (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of GDF15 mRNA and Benzo(a)pyrene results in increased expression of GDF15 mRNA CTD PMID:21569818 more ... benzo[a]pyrene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA and [Benzo(a)pyrene results in increased activity of AHR protein] which results in increased expression of GDF15 mRNA CTD PMID:27858113 and PMID:32553695 benzo[a]pyrene increases expression ISO GDF15 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of GDF15 mRNA CTD PMID:20064835 more ... benzo[a]pyrene diol epoxide I increases expression ISO GDF15 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 more ... benzo[b]fluoranthene increases expression ISO Gdf15 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of GDF15 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA CTD PMID:27858113 Benzo[ghi]perylene increases expression ISO Gdf15 (Mus musculus) 6480464 1 and 12-benzoperylene results in increased expression of GDF15 mRNA CTD PMID:26377693 Benzo[k]fluoranthene decreases expression ISO Gdf15 (Mus musculus) 6480464 benzo(k)fluoranthene results in decreased expression of GDF15 mRNA CTD PMID:26377693 beta-naphthoflavone increases expression ISO GDF15 (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of GDF15 mRNA CTD PMID:19737606 beta-naphthoflavone decreases expression ISO GDF15 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of GDF15 mRNA CTD PMID:32858204 bis(2-chloroethyl) sulfide affects expression EXP 6480464 Mustard Gas affects the expression of GDF15 mRNA CTD PMID:15651846 bis(2-chloroethyl) sulfide increases expression ISO GDF15 (Homo sapiens) 6480464 Mustard Gas results in increased expression of GDF15 mRNA CTD PMID:25102026 bis(2-ethylhexyl) phthalate increases expression ISO Gdf15 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of GDF15 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate increases expression ISO GDF15 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of GDF15 mRNA CTD PMID:31163220 bisphenol A affects expression ISO GDF15 (Homo sapiens) 6480464 bisphenol A affects the expression of GDF15 mRNA CTD PMID:20170705 and PMID:30903817 bisphenol A increases expression ISO Gdf15 (Mus musculus) 6480464 bisphenol A results in increased expression of GDF15 mRNA CTD PMID:32156529 and PMID:33221593 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of GDF15 mRNA CTD PMID:30903817 bisphenol A increases secretion ISO GDF15 (Homo sapiens) 6480464 bisphenol A results in increased secretion of GDF15 protein CTD PMID:27745655 bisphenol A increases expression ISO GDF15 (Homo sapiens) 6480464 bisphenol A results in increased expression of GDF15 mRNA CTD PMID:25047013 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GDF15 mRNA CTD PMID:25181051 and PMID:35192832 bortezomib multiple interactions ISO GDF15 (Homo sapiens) 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of GDF15 mRNA CTD PMID:25522274 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of GDF15 mRNA CTD PMID:20830808 bromoacetate increases expression ISO GDF15 (Homo sapiens) 6480464 bromoacetate results in increased expression of GDF15 mRNA CTD PMID:19753638 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of GDF15 mRNA CTD PMID:32479839 buta-1,3-diene increases expression ISO Gdf15 (Mus musculus) 6480464 1 and 3-butadiene results in increased expression of GDF15 mRNA CTD PMID:29038090 butan-1-ol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA CTD PMID:29432896 butanal increases expression ISO GDF15 (Homo sapiens) 6480464 butyraldehyde results in increased expression of GDF15 mRNA CTD PMID:26079696 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of GDF15 mRNA CTD PMID:19167457 cadmium atom multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GDF15 mRNA CTD PMID:31738976 cadmium dichloride multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GDF15 mRNA and [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 and PMID:31738976 cadmium dichloride increases expression ISO Gdf15 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of GDF15 mRNA CTD PMID:29408670 cadmium dichloride increases expression ISO GDF15 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of GDF15 mRNA CTD PMID:25596134 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GDF15 mRNA CTD PMID:19010381 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of GDF15 mRNA CTD PMID:22110744 calcitriol increases expression ISO GDF15 (Homo sapiens) 6480464 Calcitriol results in increased expression of GDF15 mRNA and Calcitriol results in increased expression of GDF15 protein CTD PMID:15386353 and PMID:16523695 cannabidiol increases expression ISO Gdf15 (Mus musculus) 6480464 Cannabidiol results in increased expression of GDF15 mRNA CTD PMID:21542829 cannabidiol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Dronabinol co-treated with Cannabidiol] results in increased expression of GDF15 mRNA CTD PMID:26504004 cannabidiol increases expression ISO GDF15 (Homo sapiens) 6480464 Cannabidiol results in increased expression of GDF15 mRNA CTD PMID:26504004 and PMID:33244087 capsaicin multiple interactions ISO GDF15 (Homo sapiens) 6480464 [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA] more ... CTD PMID:20110283 capsaicin increases phosphorylation ISO GDF15 (Homo sapiens) 6480464 Capsaicin results in increased phosphorylation of GDF15 protein CTD PMID:20110283 capsaicin increases expression ISO GDF15 (Homo sapiens) 6480464 Capsaicin results in increased expression of GDF15 mRNA CTD PMID:20110283 carbamazepine affects expression ISO GDF15 (Homo sapiens) 6480464 Carbamazepine affects the expression of GDF15 mRNA CTD PMID:25979313 carbon nanotube increases expression ISO GDF15 (Homo sapiens) 6480464 Nanotubes and Carbon results in increased expression of GDF15 mRNA CTD PMID:24389112 carbon nanotube increases expression ISO Gdf15 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 carbon nanotube decreases expression ISO Gdf15 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 carbonyl cyanide p-trifluoromethoxyphenylhydrazone increases expression ISO GDF15 (Homo sapiens) 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA CTD PMID:16039398 cefaloridine decreases expression EXP 6480464 Cephaloridine results in decreased expression of GDF15 mRNA CTD PMID:18500788 celastrol increases expression ISO GDF15 (Homo sapiens) 6480464 celastrol results in increased expression of GDF15 mRNA CTD PMID:17010675 celecoxib multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA more ... CTD PMID:17257745 more ... celecoxib increases expression ISO GDF15 (Homo sapiens) 6480464 Celecoxib results in increased expression of GDF15 and Celecoxib results in increased expression of GDF15 mRNA CTD PMID:17257745 more ... chlordecone decreases expression ISO Gdf15 (Mus musculus) 6480464 Chlordecone results in decreased expression of GDF15 mRNA CTD PMID:33711761 chloroacetaldehyde increases expression ISO GDF15 (Homo sapiens) 6480464 chloroacetaldehyde results in increased expression of GDF15 mRNA CTD PMID:25596134 chloropicrin increases expression ISO GDF15 (Homo sapiens) 6480464 chloropicrin results in increased expression of GDF15 mRNA CTD PMID:26352163 chloroprene increases expression ISO Gdf15 (Mus musculus) 6480464 Chloroprene results in increased expression of GDF15 mRNA CTD PMID:23125180 chlorpromazine increases expression EXP 6480464 Chlorpromazine results in increased expression of GDF15 mRNA CTD PMID:25596134 chlorpyrifos multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 chromium(6+) affects expression ISO Gdf15 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of GDF15 mRNA CTD PMID:28472532 chrysene decreases expression ISO Gdf15 (Mus musculus) 6480464 chrysene results in decreased expression of GDF15 mRNA CTD PMID:26377693 chrysene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA CTD PMID:27858113 cidofovir anhydrous increases expression ISO GDF15 (Homo sapiens) 6480464 Cidofovir results in increased expression of GDF15 mRNA CTD PMID:25596134 ciguatoxin CTX1B affects expression ISO Gdf15 (Mus musculus) 6480464 Ciguatoxins affects the expression of GDF15 mRNA CTD PMID:18353800 cisplatin multiple interactions ISO GDF15 (Homo sapiens) 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of GDF15 mRNA] and Folic Acid affects the reaction [Cisplatin affects the expression of GDF15 mRNA] CTD PMID:16898872 and PMID:21858171 cisplatin increases expression ISO GDF15 (Homo sapiens) 6480464 Cisplatin results in increased expression of GDF15 mRNA CTD PMID:21532991 more ... cisplatin affects expression ISO GDF15 (Homo sapiens) 6480464 Cisplatin affects the expression of GDF15 mRNA CTD PMID:23300844 cisplatin increases expression ISO Gdf15 (Mus musculus) 6480464 Cisplatin results in increased expression of GDF15 mRNA CTD PMID:21151649 clodronic acid decreases expression ISO GDF15 (Homo sapiens) 6480464 Clodronic Acid results in decreased expression of GDF15 mRNA CTD PMID:25596134 clofibrate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA] CTD PMID:17585979 clothianidin increases expression ISO GDF15 (Homo sapiens) 6480464 clothianidin results in increased expression of GDF15 mRNA CTD PMID:35690182 clozapine increases expression ISO GDF15 (Homo sapiens) 6480464 Clozapine results in increased expression of GDF15 protein CTD PMID:36482696 cobalt atom multiple interactions ISO GDF15 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which affects the expression of GDF15 mRNA CTD PMID:20105288 cobalt dichloride decreases expression ISO GDF15 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of GDF15 mRNA CTD PMID:20105288 cobalt dichloride increases expression ISO GDF15 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of GDF15 mRNA CTD PMID:19376846 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of GDF15 mRNA CTD PMID:24386269 copper atom multiple interactions ISO Gdf15 (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of GDF15 mRNA CTD PMID:15467011 copper(0) multiple interactions ISO Gdf15 (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of GDF15 mRNA CTD PMID:15467011 copper(II) sulfate increases expression ISO GDF15 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of GDF15 mRNA CTD PMID:19549813 coumestrol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA CTD PMID:19167446 coumestrol decreases expression ISO GDF15 (Homo sapiens) 6480464 Coumestrol results in decreased expression of GDF15 mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO GDF15 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of GDF15 mRNA CTD PMID:18687144 crocidolite asbestos affects expression ISO GDF15 (Homo sapiens) 6480464 Asbestos and Crocidolite affects the expression of GDF15 mRNA CTD PMID:25757056 cryptolepine increases expression ISO GDF15 (Homo sapiens) 6480464 cryptolepine results in increased expression of GDF15 mRNA CTD PMID:16120219 CU-O LINKAGE increases expression ISO GDF15 (Homo sapiens) 6480464 cupric oxide results in increased expression of GDF15 mRNA CTD PMID:22077320 cycloheximide multiple interactions ISO GDF15 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA] more ... CTD PMID:14662774 and PMID:18801729 cyclosporin A increases expression ISO GDF15 (Homo sapiens) 6480464 Cyclosporine results in increased expression of GDF15 mRNA CTD PMID:19159671 more ... cylindrospermopsin increases expression ISO GDF15 (Homo sapiens) 6480464 cylindrospermopsin results in increased expression of GDF15 mRNA CTD PMID:23726867 and PMID:24921660 daunorubicin increases expression ISO GDF15 (Homo sapiens) 6480464 Daunorubicin results in increased expression of GDF15 mRNA CTD PMID:26537877 and PMID:28940058 decabromodiphenyl ether increases expression ISO GDF15 (Homo sapiens) 6480464 decabromobiphenyl ether results in increased expression of GDF15 protein CTD PMID:31675489 deguelin increases expression ISO GDF15 (Homo sapiens) 6480464 deguelin results in increased expression of GDF15 mRNA CTD PMID:33512557 dexamethasone decreases expression ISO Gdf15 (Mus musculus) 6480464 Dexamethasone results in decreased expression of GDF15 mRNA CTD PMID:22733784 dexamethasone multiple interactions ISO GDF15 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA CTD PMID:28628672 dexamethasone decreases expression ISO GDF15 (Homo sapiens) 6480464 Dexamethasone results in decreased expression of GDF15 mRNA CTD PMID:25047013 diallyl disulfide increases expression ISO GDF15 (Homo sapiens) 6480464 diallyl disulfide results in increased expression of GDF15 protein CTD PMID:11925476 diallyl disulfide multiple interactions ISO GDF15 (Homo sapiens) 6480464 TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein] CTD PMID:11925476 diarsenic trioxide increases expression ISO GDF15 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of GDF15 mRNA CTD PMID:19036111 more ... dibenz[a,h]anthracene increases expression ISO Gdf15 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression ISO Gdf15 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of GDF15 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein CTD PMID:30218697 dibutyl phthalate decreases expression ISO Gdf15 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of GDF15 mRNA CTD PMID:17361019 and PMID:21266533 dichloroacetic acid increases expression ISO Gdf15 (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of GDF15 mRNA CTD PMID:28962523 dichromium trioxide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 diclofenac increases expression ISO Gdf15 (Mus musculus) 6480464 Diclofenac results in increased expression of GDF15 mRNA CTD PMID:18076062 diclofenac increases expression ISO GDF15 (Homo sapiens) 6480464 Diclofenac results in increased expression of GDF15 protein CTD PMID:15555568 dicrotophos increases expression ISO GDF15 (Homo sapiens) 6480464 dicrotophos results in increased expression of GDF15 mRNA CTD PMID:28302478 Didecyldimethylammonium increases expression ISO GDF15 (Homo sapiens) 6480464 didecyldimethylammonium results in increased expression of GDF15 mRNA CTD PMID:32763356 diethyl maleate increases expression ISO GDF15 (Homo sapiens) 6480464 diethyl maleate results in increased expression of GDF15 mRNA CTD PMID:33545341 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of GDF15 mRNA CTD PMID:15890375 dihydroxyacetone decreases expression ISO GDF15 (Homo sapiens) 6480464 Dihydroxyacetone results in decreased expression of GDF15 mRNA CTD PMID:32506039 dimethylarsinic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 dimethylarsinous acid increases expression ISO GDF15 (Homo sapiens) 6480464 dimethylarsinous acid results in increased expression of GDF15 mRNA CTD PMID:23487506 dioxygen multiple interactions ISO GDF15 (Homo sapiens) 6480464 Oxygen deficiency inhibits the reaction [darinaparsin results in decreased expression of GDF15 mRNA] CTD PMID:22535156 dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of GDF15 mRNA CTD PMID:33729688 dioxygen multiple interactions ISO Gdf15 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GDF15 mRNA CTD PMID:30529165 dioxygen increases expression ISO Gdf15 (Mus musculus) 6480464 Oxygen results in increased expression of GDF15 CTD PMID:28734801 dioxygen decreases expression ISO GDF15 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of GDF15 mRNA CTD PMID:26516004 dioxygen increases expression ISO GDF15 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of GDF15 mRNA more ... CTD PMID:25596134 and PMID:28734801 diquat increases expression ISO Gdf15 (Mus musculus) 6480464 Diquat results in increased expression of GDF15 mRNA CTD PMID:36851058 disodium selenite increases expression ISO GDF15 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of GDF15 mRNA CTD PMID:24383545 diuron increases expression EXP 6480464 Diuron metabolite results in increased expression of GDF15 mRNA and Diuron results in increased expression of GDF15 mRNA CTD PMID:24172598 and PMID:25152437 divanadium pentaoxide increases expression ISO GDF15 (Homo sapiens) 6480464 vanadium pentoxide results in increased expression of GDF15 mRNA CTD PMID:17459161 dorsomorphin multiple interactions ISO GDF15 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO GDF15 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of GDF15 mRNA CTD PMID:16705698 doxorubicin increases expression ISO GDF15 (Homo sapiens) 6480464 Doxorubicin results in increased expression of GDF15 mRNA CTD PMID:15205334 more ... doxorubicin decreases response to substance ISO GDF15 (Homo sapiens) 6480464 GDF15 protein results in decreased susceptibility to Doxorubicin CTD PMID:22615612 endosulfan multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA CTD PMID:26159488 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of GDF15 mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA CTD PMID:19167446 entinostat multiple interactions ISO GDF15 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA CTD PMID:27188386 entinostat increases expression ISO GDF15 (Homo sapiens) 6480464 entinostat results in increased expression of GDF15 mRNA CTD PMID:26272509 epoxiconazole decreases expression ISO Gdf15 (Mus musculus) 6480464 epoxiconazole results in decreased expression of GDF15 mRNA CTD PMID:35436446 erlotinib hydrochloride multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein CTD PMID:24979617 ethanol increases expression ISO GDF15 (Homo sapiens) 6480464 Ethanol results in increased expression of GDF15 mRNA CTD PMID:28986285 ethyl methanesulfonate increases expression ISO GDF15 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of GDF15 mRNA CTD PMID:23649840 and PMID:24211769 etoposide multiple interactions ISO GDF15 (Homo sapiens) 6480464 Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA] CTD PMID:11895857 etoposide increases expression ISO GDF15 (Homo sapiens) 6480464 [Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein more ... CTD PMID:11895857 more ... fenamidone increases expression ISO Gdf15 (Mus musculus) 6480464 fenamidone results in increased expression of GDF15 mRNA CTD PMID:27029645 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of GDF15 mRNA CTD PMID:25596134 fenofibrate increases expression ISO GDF15 (Homo sapiens) 6480464 Fenofibrate results in increased expression of GDF15 mRNA CTD PMID:25596134 fenpyroximate increases expression ISO GDF15 (Homo sapiens) 6480464 fenpyroximate results in increased expression of GDF15 mRNA CTD PMID:33512557 flurbiprofen increases expression ISO GDF15 (Homo sapiens) 6480464 Flurbiprofen results in increased expression of GDF15 protein CTD PMID:21097678 flurbiprofen multiple interactions ISO GDF15 (Homo sapiens) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Flurbiprofen results in increased expression of GDF15 protein] more ... CTD PMID:21097678 flutamide increases expression EXP 6480464 Flutamide results in increased expression of GDF15 mRNA CTD PMID:24793618 folic acid multiple interactions ISO GDF15 (Homo sapiens) 6480464 Folic Acid affects the reaction [Cisplatin affects the expression of GDF15 mRNA] CTD PMID:16898872 folic acid decreases expression ISO Gdf15 (Mus musculus) 6480464 Folic Acid results in decreased expression of GDF15 mRNA CTD PMID:25629700 formaldehyde increases expression ISO GDF15 (Homo sapiens) 6480464 Formaldehyde results in increased expression of GDF15 mRNA CTD PMID:23649840 formaldehyde decreases expression ISO GDF15 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of GDF15 mRNA CTD PMID:28937961 furan increases expression ISO Gdf15 (Mus musculus) 6480464 furan results in increased expression of GDF15 mRNA CTD PMID:24183702 more ... furan decreases expression EXP 6480464 furan results in decreased expression of GDF15 mRNA CTD PMID:26194646 furan increases methylation EXP 6480464 furan results in increased methylation of GDF15 gene CTD PMID:22079235 furan multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 gedunin increases expression ISO GDF15 (Homo sapiens) 6480464 gedunin results in increased expression of GDF15 mRNA CTD PMID:17010675 gemcitabine multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein CTD PMID:24979617 genistein increases expression ISO Gdf15 (Mus musculus) 6480464 Genistein results in increased expression of GDF15 mRNA CTD PMID:16169203 genistein increases expression ISO GDF15 (Homo sapiens) 6480464 Genistein results in increased expression of GDF15 mRNA CTD PMID:22228119 and PMID:26865667 genistein decreases expression ISO GDF15 (Homo sapiens) 6480464 Genistein results in decreased expression of GDF15 mRNA CTD PMID:20884965 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of GDF15 mRNA CTD PMID:22061828 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of GDF15 mRNA CTD PMID:33387578 gingerol multiple interactions ISO GDF15 (Homo sapiens) 6480464 GSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein] more ... CTD PMID:18058799 gingerol increases expression ISO GDF15 (Homo sapiens) 6480464 gingerol results in increased expression of GDF15 mRNA and gingerol results in increased expression of GDF15 protein CTD PMID:18058799 glyphosate multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 graphene oxide decreases expression ISO Gdf15 (Mus musculus) 6480464 graphene oxide results in decreased expression of GDF15 mRNA CTD PMID:33227293 graphite affects expression EXP 6480464 Graphite affects the expression of GDF15 mRNA CTD PMID:29933104 hydrogen peroxide affects expression ISO GDF15 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of GDF15 mRNA CTD PMID:20044591 hydrogen peroxide decreases expression ISO Gdf15 (Mus musculus) 6480464 Hydrogen Peroxide results in decreased expression of GDF15 mRNA CTD PMID:35123994 hydrogen peroxide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein CTD PMID:18951874 hydrogen peroxide increases expression ISO GDF15 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of GDF15 more ... CTD PMID:12414654 more ... hydroquinone increases expression ISO GDF15 (Homo sapiens) 6480464 hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264 and PMID:31256213 hydroxyurea increases expression ISO GDF15 (Homo sapiens) 6480464 Hydroxyurea results in increased expression of GDF15 mRNA CTD PMID:24211769 ibuprofen increases expression ISO GDF15 (Homo sapiens) 6480464 Ibuprofen results in increased expression of GDF15 mRNA and Ibuprofen results in increased expression of GDF15 protein CTD PMID:15555568 more ... ibuprofen multiple interactions ISO GDF15 (Homo sapiens) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ibuprofen results in increased expression of GDF15 protein] more ... CTD PMID:21097678 ifosfamide increases expression ISO GDF15 (Homo sapiens) 6480464 Ifosfamide results in increased expression of GDF15 mRNA CTD PMID:25596134 imidacloprid multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 imidazopyrazole increases expression ISO GDF15 (Homo sapiens) 6480464 imidazopyrazole analog results in increased expression of GDF15 mRNA CTD PMID:30388846 indole-3-methanol increases expression ISO GDF15 (Homo sapiens) 6480464 indole-3-carbinol results in increased expression of GDF15 CTD PMID:15670751 indole-3-methanol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [indole-3-carbinol co-treated with resveratrol] results in increased expression of GDF15 CTD PMID:15670751 indometacin increases expression ISO Gdf15 (Mus musculus) 6480464 Indomethacin results in increased expression of GDF15 mRNA CTD PMID:18076062 indometacin multiple interactions ISO GDF15 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA CTD PMID:28628672 indometacin decreases response to substance ISO GDF15 (Homo sapiens) 6480464 GDF15 protein results in decreased susceptibility to Indomethacin CTD PMID:22615612 indometacin increases expression ISO GDF15 (Homo sapiens) 6480464 Indomethacin results in increased expression of GDF15 mRNA and Indomethacin results in increased expression of GDF15 protein CTD PMID:15180942 more ... inulin multiple interactions ISO Gdf15 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of GDF15 mRNA CTD PMID:36331819 irinotecan increases expression ISO GDF15 (Homo sapiens) 6480464 Irinotecan metabolite results in increased expression of GDF15 mRNA and Irinotecan results in increased expression of GDF15 mRNA CTD PMID:15956246 iron dichloride increases expression ISO GDF15 (Homo sapiens) 6480464 ferrous chloride results in increased expression of GDF15 mRNA CTD PMID:35984750 isotretinoin increases expression ISO GDF15 (Homo sapiens) 6480464 Isotretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 ivermectin increases expression ISO Gdf15 (Mus musculus) 6480464 Ivermectin results in increased expression of GDF15 mRNA CTD PMID:28942281 ivermectin decreases expression ISO GDF15 (Homo sapiens) 6480464 Ivermectin results in decreased expression of GDF15 protein CTD PMID:32959892 jaspamide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] CTD PMID:23996089 jaspamide increases expression ISO GDF15 (Homo sapiens) 6480464 jasplakinolide results in increased expression of GDF15 mRNA and jasplakinolide results in increased expression of GDF15 protein CTD PMID:23996089 Lasiocarpine increases expression ISO GDF15 (Homo sapiens) 6480464 lasiocarpine results in increased expression of GDF15 mRNA CTD PMID:32234424 and PMID:35690182 latrunculin B multiple interactions ISO GDF15 (Homo sapiens) 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein] CTD PMID:23996089 latrunculin B increases expression ISO GDF15 (Homo sapiens) 6480464 latrunculin B results in increased expression of GDF15 mRNA and latrunculin B results in increased expression of GDF15 protein CTD PMID:23996089 lead diacetate multiple interactions ISO GDF15 (Homo sapiens) 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 leflunomide increases expression ISO GDF15 (Homo sapiens) 6480464 leflunomide results in increased expression of GDF15 mRNA CTD PMID:28988120 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of GDF15 mRNA CTD PMID:35283115 lipopolysaccharide decreases expression ISO Gdf15 (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of GDF15 mRNA CTD PMID:27339419 lipopolysaccharide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of GDF15 mRNA more ... CTD PMID:35811015 and PMID:35877022 lucanthone increases expression ISO GDF15 (Homo sapiens) 6480464 Lucanthone results in increased expression of GDF15 mRNA CTD PMID:21148553 manganese atom increases expression ISO GDF15 (Homo sapiens) 6480464 Manganese results in increased expression of GDF15 mRNA CTD PMID:17175027 manganese(0) increases expression ISO GDF15 (Homo sapiens) 6480464 Manganese results in increased expression of GDF15 mRNA CTD PMID:17175027 manganese(II) chloride increases expression ISO GDF15 (Homo sapiens) 6480464 manganese chloride results in increased expression of GDF15 mRNA CTD PMID:17175027 menadione affects expression ISO GDF15 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of GDF15 mRNA CTD PMID:20044591 menadione increases expression ISO GDF15 (Homo sapiens) 6480464 Vitamin K 3 results in increased expression of GDF15 mRNA CTD PMID:12414654 mercury dibromide increases expression ISO GDF15 (Homo sapiens) 6480464 mercuric bromide results in increased expression of GDF15 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA CTD PMID:27188386 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of GDF15 mRNA CTD PMID:16507785 metacetamol decreases expression ISO Gdf15 (Mus musculus) 6480464 3-hydroxyacetanilide results in decreased expression of GDF15 mRNA CTD PMID:18544908 metformin increases expression EXP 6480464 Metformin results in increased expression of GDF15 mRNA CTD PMID:25596134 methamphetamine increases expression ISO GDF15 (Homo sapiens) 6480464 Methamphetamine results in increased expression of GDF15 mRNA CTD PMID:25290377 methamphetamine increases expression ISO Gdf15 (Mus musculus) 6480464 Methamphetamine results in increased expression of GDF15 mRNA CTD PMID:36914120 methamphetamine multiple interactions EXP 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA and GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA] CTD PMID:19564919 and PMID:36914120 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of GDF15 mRNA CTD PMID:19564919 and PMID:36914120 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of GDF15 mRNA CTD PMID:15890375 and PMID:30467583 methyl methanesulfonate increases expression ISO GDF15 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of GDF15 mRNA CTD PMID:23649840 and PMID:24211769 methylarsonic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 methylmercury chloride increases expression ISO GDF15 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of GDF15 mRNA CTD PMID:26272509 and PMID:28001369 methylparaben increases expression ISO GDF15 (Homo sapiens) 6480464 methylparaben results in increased expression of GDF15 mRNA CTD PMID:31745603 mitomycin C increases expression ISO GDF15 (Homo sapiens) 6480464 Mitomycin results in increased expression of GDF15 mRNA CTD PMID:24211769 Mitotane increases expression ISO GDF15 (Homo sapiens) 6480464 Mitotane results in increased expression of GDF15 mRNA CTD PMID:22966885 mitoxantrone increases expression ISO GDF15 (Homo sapiens) 6480464 Mitoxantrone results in increased expression of GDF15 mRNA CTD PMID:26537877 and PMID:28940058 mono(2-ethylhexyl) phthalate increases expression ISO GDF15 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of GDF15 mRNA CTD PMID:36695872 N(4)-hydroxycytidine decreases expression ISO Gdf15 (Mus musculus) 6480464 N(4)-hydroxycytidine results in decreased expression of GDF15 mRNA CTD PMID:37748715 N-acetyl-L-cysteine multiple interactions ISO Gdf15 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA] CTD PMID:35123994 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Gdf15 (Mus musculus) 6480464 MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA] CTD PMID:25566086 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO Gdf15 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA CTD PMID:25566086 N-ethyl-N-nitrosourea increases expression ISO Gdf15 (Mus musculus) 6480464 Ethylnitrosourea results in increased expression of GDF15 mRNA CTD PMID:19100860 N-methyl-4-phenylpyridinium increases expression ISO GDF15 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of GDF15 mRNA CTD PMID:24810058 N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO GDF15 (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA CTD PMID:12634122 and PMID:12773770 N-methylformamide increases expression ISO Gdf15 (Mus musculus) 6480464 methylformamide analog results in increased expression of GDF15 mRNA and methylformamide results in increased expression of GDF15 mRNA CTD PMID:17040096 N-nitrosodiethylamine increases expression ISO GDF15 (Homo sapiens) 6480464 Diethylnitrosamine results in increased expression of GDF15 mRNA CTD PMID:21527772 N-nitrosodiethylamine increases expression ISO Gdf15 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of GDF15 mRNA CTD PMID:19100860 and PMID:21607683 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of GDF15 mRNA CTD PMID:14600272 and PMID:15890375 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of GDF15 mRNA CTD PMID:19716841 N-Nitrosopyrrolidine increases expression ISO GDF15 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in increased expression of GDF15 mRNA CTD PMID:32234424 and PMID:35690182 naphthalene increases expression ISO Gdf15 (Mus musculus) 6480464 naphthalene results in increased expression of GDF15 mRNA CTD PMID:18978301 naphthalene increases expression EXP 6480464 naphthalene analog results in increased expression of GDF15 mRNA CTD PMID:24976557 nickel dichloride increases expression ISO GDF15 (Homo sapiens) 6480464 nickel chloride results in increased expression of GDF15 mRNA CTD PMID:17312168 nickel sulfate increases expression ISO GDF15 (Homo sapiens) 6480464 nickel sulfate results in increased expression of GDF15 mRNA CTD PMID:18651567 niclosamide increases expression ISO GDF15 (Homo sapiens) 6480464 Niclosamide results in increased expression of GDF15 mRNA CTD PMID:36318118 NS-398 increases expression ISO GDF15 (Homo sapiens) 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of GDF15 protein CTD PMID:15180942 Nutlin-3 increases expression ISO GDF15 (Homo sapiens) 6480464 nutlin 3 results in increased expression of GDF15 mRNA CTD PMID:16439677 O-methyleugenol increases expression ISO GDF15 (Homo sapiens) 6480464 methyleugenol results in increased expression of GDF15 mRNA CTD PMID:32234424 and PMID:35690182 Octicizer multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 octreotide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA CTD PMID:17959037 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of GDF15 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of GDF15 mRNA CTD PMID:25729387 ozone multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of GDF15 mRNA CTD PMID:34911549 p-chloromercuribenzoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of GDF15 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO GDF15 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA CTD PMID:27188386 paracetamol multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA] CTD PMID:17585979 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of GDF15 mRNA CTD PMID:33387578 paracetamol increases expression ISO GDF15 (Homo sapiens) 6480464 Acetaminophen results in increased expression of GDF15 mRNA CTD PMID:29067470 paracetamol affects expression ISO Gdf15 (Mus musculus) 6480464 Acetaminophen affects the expression of GDF15 mRNA CTD PMID:17562736 paracetamol increases expression ISO Gdf15 (Mus musculus) 6480464 Acetaminophen results in increased expression of GDF15 mRNA CTD PMID:18544908 and PMID:26056430 paraquat increases expression ISO GDF15 (Homo sapiens) 6480464 Paraquat results in increased expression of GDF15 mRNA CTD PMID:20883675 more ... paraquat increases expression EXP 6480464 Paraquat results in increased expression of GDF15 mRNA CTD PMID:32680482 pentanal increases expression ISO GDF15 (Homo sapiens) 6480464 pentanal results in increased expression of GDF15 mRNA CTD PMID:26079696 perfluorodecanoic acid decreases expression ISO GDF15 (Homo sapiens) 6480464 perfluorodecanoic acid results in decreased expression of GDF15 protein CTD PMID:32916415 perfluorononanoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of GDF15 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression ISO GDF15 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of GDF15 mRNA CTD PMID:27153767 perfluorooctane-1-sulfonic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GDF15 mRNA more ... CTD PMID:36331819 perfluorooctanoic acid increases expression ISO GDF15 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of GDF15 mRNA and perfluorooctanoic acid results in increased expression of GDF15 protein CTD PMID:26879310 and PMID:36326898 perfluoroundecanoic acid decreases expression ISO GDF15 (Homo sapiens) 6480464 perfluoroundecanoic acid results in decreased expression of GDF15 protein CTD PMID:32916415 phenobarbital multiple interactions ISO Gdf15 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GDF15 mRNA] and NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of GDF15 mRNA] CTD PMID:19482888 and PMID:19850644 phenobarbital increases expression ISO Gdf15 (Mus musculus) 6480464 Phenobarbital results in increased expression of GDF15 mRNA CTD PMID:19482888 more ... phenylephrine affects expression ISO GDF15 (Homo sapiens) 6480464 Phenylephrine affects the expression of GDF15 mRNA CTD PMID:19505289 phenylmercury acetate increases expression ISO GDF15 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of GDF15 mRNA CTD PMID:26272509 phloroglucinol increases expression ISO GDF15 (Homo sapiens) 6480464 Phloroglucinol analog results in increased expression of GDF15 protein CTD PMID:23178381 phorbol 13-acetate 12-myristate multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein and [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] CTD PMID:23996089 and PMID:30218697 phorbol 13-acetate 12-myristate increases expression ISO GDF15 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein CTD PMID:23996089 phosgene affects expression ISO Gdf15 (Mus musculus) 6480464 Phosgene affects the expression of GDF15 mRNA CTD PMID:16300373 picoxystrobin increases expression ISO GDF15 (Homo sapiens) 6480464 picoxystrobin results in increased expression of GDF15 mRNA CTD PMID:33512557 pinosylvin increases expression ISO GDF15 (Homo sapiens) 6480464 pinosylvin results in increased expression of GDF15 mRNA and pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 pioglitazone multiple interactions ISO Gdf15 (Mus musculus) 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GDF15 mRNA CTD PMID:27935865 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of GDF15 mRNA CTD PMID:15890375 pirinixic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GDF15 mRNA and PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GDF15 mRNA] CTD PMID:19710929 and PMID:19850644 pirinixic acid increases expression ISO Gdf15 (Mus musculus) 6480464 pirinixic acid results in increased expression of GDF15 mRNA CTD PMID:18445702 more ... pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of GDF15 mRNA CTD PMID:15890375 piroxicam multiple interactions ISO GDF15 (Homo sapiens) 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of GDF15 mRNA] CTD PMID:21858171 piroxicam decreases expression ISO GDF15 (Homo sapiens) 6480464 Piroxicam results in decreased expression of GDF15 mRNA CTD PMID:21858171 platycodin D increases expression ISO GDF15 (Homo sapiens) 6480464 platycodin D results in increased expression of GDF15 protein CTD PMID:18804340 potassium dichromate increases expression ISO GDF15 (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of GDF15 mRNA CTD PMID:18332044 progesterone increases expression ISO GDF15 (Homo sapiens) 6480464 Progesterone results in increased expression of GDF15 mRNA CTD PMID:18037150 progesterone decreases expression ISO Gdf15 (Mus musculus) 6480464 Progesterone results in decreased expression of GDF15 mRNA CTD PMID:22238285 progesterone increases expression EXP 6480464 Progesterone results in increased expression of GDF15 mRNA CTD PMID:20726854 progesterone multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA CTD PMID:20660070 propanal increases expression ISO GDF15 (Homo sapiens) 6480464 propionaldehyde results in increased expression of GDF15 mRNA CTD PMID:26079696 prostaglandin J2 increases expression ISO GDF15 (Homo sapiens) 6480464 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 mRNA and 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein CTD PMID:14662774 prostaglandin J2 multiple interactions ISO GDF15 (Homo sapiens) 6480464 [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein] CTD PMID:14662774 pterostilbene increases expression ISO GDF15 (Homo sapiens) 6480464 pterostilbene results in increased expression of GDF15 mRNA CTD PMID:22450950 pyrimidifen increases expression ISO GDF15 (Homo sapiens) 6480464 pyrimidifen results in increased expression of GDF15 mRNA CTD PMID:33512557 quercetin decreases expression ISO GDF15 (Homo sapiens) 6480464 Quercetin results in decreased expression of GDF15 mRNA CTD PMID:15309432 quercetin increases expression ISO GDF15 (Homo sapiens) 6480464 Quercetin results in increased expression of GDF15 mRNA CTD PMID:21632981 resveratrol multiple interactions ISO GDF15 (Homo sapiens) 6480464 [indole-3-carbinol co-treated with resveratrol] results in increased expression of GDF15 more ... CTD PMID:11895857 more ... resveratrol increases expression ISO GDF15 (Homo sapiens) 6480464 [Resveratrol results in increased expression of TP53 protein] which results in increased expression of GDF15 protein more ... CTD PMID:11895857 and PMID:17257620 Ro 31-8220 multiple interactions ISO GDF15 (Homo sapiens) 6480464 Ro 31-8220 inhibits the reaction [gingerol results in increased expression of GDF15 protein] CTD PMID:18058799 rotenone increases expression EXP 6480464 Rotenone results in increased expression of GDF15 mRNA CTD PMID:27900601 rotenone increases expression ISO GDF15 (Homo sapiens) 6480464 Rotenone results in increased expression of GDF15 mRNA CTD PMID:29955902 and PMID:33512557 rottlerin increases expression ISO GDF15 (Homo sapiens) 6480464 rottlerin results in increased expression of GDF15 mRNA and rottlerin results in increased expression of GDF15 protein CTD PMID:22410117 rottlerin multiple interactions ISO GDF15 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [rottlerin results in increased expression of GDF15 protein] and SB 203580 inhibits the reaction [rottlerin results in increased expression of GDF15 protein] CTD PMID:22410117 rottlerin affects response to substance ISO GDF15 (Homo sapiens) 6480464 GDF15 affects the susceptibility to rottlerin CTD PMID:22410117 S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO GDF15 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased expression of GDF15 mRNA CTD PMID:36576512 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO GDF15 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of GDF15 mRNA CTD PMID:35811015 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO Gdf15 (Mus musculus) 6480464 Buthionine Sulfoximine results in increased expression of GDF15 mRNA CTD PMID:35123994 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO Gdf15 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA] CTD PMID:35123994 SB 203580 multiple interactions ISO GDF15 (Homo sapiens) 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] more ... CTD PMID:22410117 more ... SB 431542 multiple interactions ISO GDF15 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SCH 23390 multiple interactions EXP 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA CTD PMID:19564919 Securinine increases expression ISO GDF15 (Homo sapiens) 6480464 securinine results in increased expression of GDF15 mRNA CTD PMID:32662633 serpentine asbestos increases expression ISO GDF15 (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of GDF15 mRNA CTD PMID:24160326 silibinin increases expression ISO GDF15 (Homo sapiens) 6480464 Silybin results in increased expression of GDF15 mRNA and Silybin results in increased expression of GDF15 protein CTD PMID:24440808 silibinin multiple interactions ISO GDF15 (Homo sapiens) 6480464 EGR1 mutant form inhibits the reaction [Silybin results in increased expression of GDF15 protein] more ... CTD PMID:24440808 silicon dioxide increases expression ISO GDF15 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of GDF15 mRNA CTD PMID:23806026 silicon dioxide increases expression ISO Gdf15 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of GDF15 mRNA CTD PMID:19073995 more ... silver atom increases expression ISO Gdf15 (Mus musculus) 6480464 Silver results in increased expression of GDF15 mRNA CTD PMID:27131904 silver(0) increases expression ISO Gdf15 (Mus musculus) 6480464 Silver results in increased expression of GDF15 mRNA CTD PMID:27131904 sodium arsenate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 sodium arsenite decreases expression ISO GDF15 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of GDF15 mRNA CTD PMID:12634122 and PMID:34032870 sodium arsenite multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 sodium arsenite increases expression ISO Gdf15 (Mus musculus) 6480464 sodium arsenite results in increased expression of GDF15 mRNA CTD PMID:16014739 sodium arsenite increases expression ISO GDF15 (Homo sapiens) 6480464 sodium arsenite results in increased expression of GDF15 mRNA and sodium arsenite results in increased expression of GDF15 protein CTD PMID:23876855 more ... sodium arsenite multiple interactions ISO GDF15 (Homo sapiens) 6480464 [sodium arsenite affects the acetylation of H3-4 protein] which affects the methylation of GDF15 promoter and [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 and PMID:18448484 sulindac increases expression ISO GDF15 (Homo sapiens) 6480464 Sulindac results in increased expression of GDF15 mRNA and Sulindac results in increased expression of GDF15 protein CTD PMID:11906190 and PMID:15180942 sulindac increases expression ISO Gdf15 (Mus musculus) 6480464 Sulindac results in increased expression of GDF15 protein CTD PMID:11984525 sulindac sulfide multiple interactions ISO GDF15 (Homo sapiens) 6480464 EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of GDF15 mRNA] CTD PMID:15509713 sulindac sulfide increases expression ISO Gdf15 (Mus musculus) 6480464 sulindac sulfide results in increased expression of GDF15 mRNA CTD PMID:18076062 sulindac sulfide increases expression ISO GDF15 (Homo sapiens) 6480464 sulindac sulfide results in increased expression of GDF15 mRNA and sulindac sulfide results in increased expression of GDF15 protein CTD PMID:11895857 more ... sunitinib increases expression ISO GDF15 (Homo sapiens) 6480464 Sunitinib results in increased expression of GDF15 mRNA CTD PMID:31533062 T-2 toxin increases expression ISO GDF15 (Homo sapiens) 6480464 T-2 Toxin results in increased expression of GDF15 mRNA CTD PMID:34581912 tamoxifen increases expression ISO Gdf15 (Mus musculus) 6480464 Tamoxifen results in increased expression of GDF15 mRNA CTD PMID:25123088 tamoxifen decreases response to substance ISO GDF15 (Homo sapiens) 6480464 GDF15 protein results in decreased susceptibility to Tamoxifen CTD PMID:22615612 tamoxifen affects expression ISO Gdf15 (Mus musculus) 6480464 Tamoxifen affects the expression of GDF15 mRNA CTD PMID:20937368 tebufenpyrad increases expression ISO GDF15 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of GDF15 mRNA CTD PMID:33512557 temozolomide increases expression ISO GDF15 (Homo sapiens) 6480464 Temozolomide results in increased expression of GDF15 mRNA CTD PMID:31758290 tert-butyl hydroperoxide increases expression ISO GDF15 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of GDF15 mRNA CTD PMID:12414654 tetrachloromethane increases expression ISO Gdf15 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of GDF15 mRNA CTD PMID:31919559 tetraphene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA CTD PMID:27858113 thapsigargin increases expression ISO GDF15 (Homo sapiens) 6480464 Thapsigargin results in increased expression of GDF15 mRNA CTD PMID:22378314 theophylline multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein CTD PMID:18951874 thiabendazole multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 thifluzamide increases expression ISO GDF15 (Homo sapiens) 6480464 thifluzamide results in increased expression of GDF15 mRNA CTD PMID:33512557 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of GDF15 mRNA CTD PMID:23411599 and PMID:34492290 thiostrepton increases expression ISO GDF15 (Homo sapiens) 6480464 Thiostrepton results in increased expression of GDF15 mRNA CTD PMID:22321511 titanium dioxide increases expression ISO Gdf15 (Mus musculus) 6480464 titanium dioxide results in increased expression of GDF15 mRNA CTD PMID:23557971 titanium dioxide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [Vitallium analog binds to titanium dioxide] which results in increased expression of GDF15 mRNA CTD PMID:23825117 topotecan increases expression EXP 6480464 Topotecan results in increased expression of GDF15 mRNA CTD PMID:25729387 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of GDF15 mRNA CTD PMID:25729387 trans-pinosylvin increases expression ISO GDF15 (Homo sapiens) 6480464 pinosylvin results in increased expression of GDF15 mRNA and pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 tributyl phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 trichloroethene increases expression ISO Gdf15 (Mus musculus) 6480464 Trichloroethylene results in increased expression of GDF15 mRNA CTD PMID:25549359 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of GDF15 mRNA CTD PMID:33387578 trichostatin A multiple interactions ISO GDF15 (Homo sapiens) 6480464 [trichostatin A results in increased expression of GDF15 protein] which results in increased cleavage of PARP1 protein more ... CTD PMID:18801729 trichostatin A increases expression ISO GDF15 (Homo sapiens) 6480464 trichostatin A results in increased expression of GDF15 mRNA CTD PMID:24935251 triphenyl phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 triptonide increases expression ISO Gdf15 (Mus musculus) 6480464 triptonide results in increased expression of GDF15 mRNA CTD PMID:33045310 tris(2-butoxyethyl) phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 tris(2-chloroethyl) phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 troglitazone multiple interactions ISO GDF15 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [troglitazone results in increased expression of GDF15 protein] more ... CTD PMID:14662774 troglitazone increases expression ISO GDF15 (Homo sapiens) 6480464 troglitazone results in increased expression of GDF15 mRNA and troglitazone results in increased expression of GDF15 protein CTD PMID:14662774 more ... Tungsten carbide multiple interactions ISO GDF15 (Homo sapiens) 6480464 [tungsten carbide binds to Cobalt] which affects the expression of GDF15 mRNA CTD PMID:20105288 tunicamycin increases expression ISO GDF15 (Homo sapiens) 6480464 Tunicamycin results in increased expression of GDF15 mRNA CTD PMID:22378314 urethane increases expression ISO GDF15 (Homo sapiens) 6480464 Urethane results in increased expression of GDF15 mRNA CTD PMID:28818685 valproic acid affects expression ISO GDF15 (Homo sapiens) 6480464 Valproic Acid affects the expression of GDF15 mRNA CTD PMID:25979313 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GDF15 mRNA CTD PMID:35594946 valproic acid increases expression ISO GDF15 (Homo sapiens) 6480464 Valproic Acid results in increased expression of GDF15 mRNA CTD PMID:23179753 more ... vincristine increases expression ISO GDF15 (Homo sapiens) 6480464 Vincristine results in increased expression of GDF15 mRNA CTD PMID:23649840 wortmannin increases expression ISO GDF15 (Homo sapiens) 6480464 wortmannin results in increased expression of GDF15 protein CTD PMID:23178381 zinc atom multiple interactions ISO GDF15 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of GDF15 mRNA CTD PMID:18593933 zinc atom multiple interactions EXP 6480464 Zinc inhibits the reaction [Zinc deficiency results in increased expression of GDF15 mRNA] CTD PMID:19111725 zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of GDF15 mRNA CTD PMID:19111725 zinc oxide decreases expression EXP 6480464 Zinc Oxide results in decreased expression of GDF15 protein CTD PMID:33205376 zinc pyrithione increases expression ISO GDF15 (Homo sapiens) 6480464 pyrithione zinc results in increased expression of GDF15 mRNA CTD PMID:21424779 zinc(0) multiple interactions ISO GDF15 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of GDF15 mRNA CTD PMID:18593933 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of GDF15 mRNA CTD PMID:19111725 zinc(0) multiple interactions EXP 6480464 Zinc inhibits the reaction [Zinc deficiency results in increased expression of GDF15 mRNA] CTD PMID:19111725 zoledronic acid decreases expression ISO GDF15 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of GDF15 mRNA CTD PMID:24714768 and PMID:25596134