Gene: Gdf15 (growth differentiation factor 15) Rattus norvegicus
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Symbol: Gdf15
Name: growth differentiation factor 15
Description: ENCODES a protein that exhibits protein homodimerization activity; INVOLVED IN activation of MAPK activity (ortholog); glial cell-derived neurotrophic factor receptor signaling pathway (ortholog); negative regulation of growth hormone receptor signaling pathway (ortholog); ASSOCIATED WITH anemia (ortholog); congestive heart failure (ortholog); coronary artery disease (ortholog); FOUND IN extracellular region; cytoplasm (ortholog); extracellular space (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GDF-15; growth/differentiation factor 15
Orthologs:
Homo sapiens (human) : GDF15 (growth differentiation factor 15)  HGNC  Alliance
Mus musculus (house mouse) : Gdf15 (growth differentiation factor 15)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf15 (growth differentiation factor 15)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF15 (growth differentiation factor 15)
Canis lupus familiaris (dog) : GDF15 (growth differentiation factor 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf15 (growth differentiation factor 15)
Sus scrofa (pig) : GDF15 (growth differentiation factor 15)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,555,395 - 20,557,978 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01620,411,167 - 20,413,750 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,310,882 - 19,313,465 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,310,851 - 19,313,463 (+)NCBI
Celera1618,997,242 - 18,999,829 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gdf15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2674
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE