Gpx1 (glutathione peroxidase 1) - Rat Genome Database

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Gene: Gpx1 (glutathione peroxidase 1) Rattus norvegicus
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Symbol: Gpx1
Name: glutathione peroxidase 1
RGD ID: 2729
Description: Enables glutathione peroxidase activity. Involved in several processes, including cellular response to glucose stimulus; hydrogen peroxide catabolic process; and response to estradiol. Located in cytosol; mitochondrion; and nucleus. Used to study several diseases, including cataract; gestational diabetes; hypertension; hyperthyroidism; and hypothyroidism. Biomarker of hyperhomocysteinemia; hypertension; iron deficiency anemia; and vascular dementia. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Orthologous to human GPX1 (glutathione peroxidase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; (+)-taxifolin; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cellular glutathione peroxidase; GPx-1; GSHPx; GSHPx-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28109,026,905 - 109,028,031 (+)NCBI
Rnor_6.0 Ensembl8117,117,430 - 117,118,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08117,117,430 - 117,118,528 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,466,118 - 116,467,216 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,329,847 - 108,330,945 (+)ENTREZGENECelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
Aicardi-Goutieres Syndrome 1  (ISO)
alpha thalassemia  (ISO)
anemia  (IDA,ISO)
Anorexia  (ISO)
arteriosclerosis  (ISO)
autistic disorder  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2P  (ISO)
Brain Injuries  (IEP)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
Cadmium Poisoning  (IEP)
calcinosis  (ISO)
Cardiovascular Abnormalities  (ISO)
cardiovascular system disease  (ISO)
carotid stenosis  (ISO)
cataract  (IDA)
Chronic Hepatitis  (ISO)
chronic kidney disease  (ISO)
chronic myeloid leukemia  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
dilated cardiomyopathy  (ISO)
epilepsy  (ISO)
Experimental Diabetes Mellitus  (IEP,ISO)
fatty liver disease  (ISO)
gestational diabetes  (IDA)
Glutathione Peroxidase Deficiency, Hemolytic Anemia possibly due to  (ISO)
hairy cell leukemia  (ISO)
Head and Neck Neoplasms  (ISO)
Hemolysis  (ISO)
Huntington's disease  (ISO)
hyperglycemia  (ISO)
hyperhomocysteinemia  (IEP)
hyperinsulinism  (ISO)
hypertension  (IDA,IEP,ISO)
hyperthyroidism  (IDA,ISO)
hypothyroidism  (IDA)
iron deficiency anemia  (IEP,ISO)
Iron Overload  (ISO)
Keshan disease  (ISO)
leukemia  (ISO)
Liver Injury  (IDA)
Lung Neoplasms  (ISO)
mental depression  (ISO)
Mercury Poisoning  (ISO)
multiple myeloma  (ISO)
myeloid neoplasm  (ISO)
myocardial infarction  (ISO)
nephrosis  (ISO)
non-alcoholic fatty liver disease  (ISO)
non-Hodgkin lymphoma  (ISO)
obesity  (ISO)
osteoporosis  (ISO)
Parkinson's disease  (ISO)
Pierson syndrome  (ISO)
pseudoxanthoma elasticum  (ISO)
Reperfusion Injury  (ISO)
Reticulocytosis  (ISO)
senile cataract  (ISO)
sickle cell anemia  (ISO)
squamous cell carcinoma  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
vascular dementia  (IEP)
Venous Thrombosis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(+)-taxifolin  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-quinic acid  (ISO)
(R)-carnitine  (EXP)
(R)-lipoic acid  (EXP,ISO)
(S)-colchicine  (EXP)
(S)-naringenin  (EXP)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,4,7-triazonane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP)
11-deoxycorticosterone  (EXP)
12(S)-HPETE  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-tert-butylhydroquinone  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-dihydroxybenzoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (EXP,ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nonylphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acetic acid  (EXP)
acetylcholine  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
alpha,alpha-trehalose  (EXP)
aluminium atom  (ISO)
aluminium(0)  (ISO)
AM-251  (ISO)
aminoglutethimide  (ISO)
aminoguanidine  (EXP)
amiodarone  (EXP)
amlexanox  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
amphibole asbestos  (ISO)
ampicillin  (EXP)
apigenin  (ISO)
apocynin  (EXP,ISO)
arachidonic acid  (ISO)
Aroclor 1254  (EXP)
arsenic acid  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
atrasentan  (EXP)
atrazine  (EXP,ISO)
auranofin  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzopyran  (EXP)
berberine  (EXP)
beta-naphthoflavone  (EXP)
bifenthrin  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
bosentan  (ISO)
bromobenzene  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcium dichloride  (ISO)
camphene  (EXP)
capsaicin  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
carnosine  (ISO)
celecoxib  (ISO)
chitosan  (EXP)
chloramine T  (EXP)
chloroform  (EXP)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
chromium atom  (ISO)
chromium(6+)  (EXP,ISO)
ciprofibrate  (EXP)
cisplatin  (EXP,ISO)
clobetasol  (ISO)
clofibrate  (EXP)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
coenzyme Q10  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
coumarin  (EXP)
CU-O LINKAGE  (ISO)
cumene hydroperoxide  (ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyfluthrin  (ISO)
cypermethrin  (ISO)
cyprodinil  (ISO)
cytochalasin D  (ISO)
D-glucose  (EXP,ISO)
daunorubicin  (ISO)
DDE  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (ISO)
diclofenac  (EXP,ISO)
dieldrin  (EXP,ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dihydrogen  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
Diphenyl disulfide  (ISO)
diprotium  (ISO)
diprotium oxide  (ISO)
diquat  (ISO)
disodium selenite  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ebselen  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (EXP)
emodin  (ISO)
endosulfan  (EXP)
enilconazole  (ISO)
enniatin  (ISO)
erythromycin estolate  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenamidone  (ISO)
fenofibrate  (ISO)
flavonoids  (EXP)
fludioxonil  (ISO)
flutamide  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fructose  (EXP)
Galbanic acid  (ISO)
geneticin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (EXP)
ginsenoside Re  (ISO)
Ginsenoside Rh4  (ISO)
glafenine  (EXP)
glucose  (EXP,ISO)
glutathione  (ISO)
glyphosate  (EXP)
GW 4064  (ISO)
haloperidol  (ISO)
hexadecanoic acid  (ISO)
homocysteine  (ISO)
hydrazine  (EXP)
hydrogen peroxide  (EXP,ISO)
hypochlorous acid  (ISO)
ifosfamide  (EXP)
iloprost  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (ISO)
indometacin  (EXP,ISO)
iron atom  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP)
jaspamide  (ISO)
kainic acid  (ISO)
kojic acid  (EXP)
L-ascorbic acid  (EXP,ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leptomycin B  (ISO)
limonene  (EXP)
linoleic acid hydroperoxide  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (ISO)
lovastatin  (ISO)
lutein  (ISO)
luteolin  (ISO)
Magnolol  (EXP)
mancozeb  (ISO)
maneb  (EXP,ISO)
manganese(II) chloride  (ISO)
melatonin  (EXP,ISO)
menadione  (ISO)
mephedrone  (EXP,ISO)
mercury atom  (ISO)
mercury dichloride  (EXP)
mercury(0)  (ISO)
methotrexate  (EXP,ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylglyoxal  (EXP)
methylmercury chloride  (EXP,ISO)
methylmercury(1+)  (ISO)
metronidazole  (EXP)
microcystin  (EXP)
microcystin-LR  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (ISO)
monoethyl phthalate  (ISO)
monosodium L-glutamate  (ISO)
motexafin gadolinium  (ISO)
myricitrin  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (ISO)
naringin  (ISO)
nefazodone  (EXP)
neomycin  (EXP)
nickel atom  (EXP)
nickel dichloride  (EXP)
nickel subsulfide  (ISO)
nicotine  (EXP,ISO)
nimesulide  (EXP,ISO)
nitric oxide  (ISO)
nitroglycerin  (ISO)
Nodularin  (ISO)
NONOate(1-)  (ISO)
Nonylphenol  (ISO)
NS-398  (ISO)
NSC 23766  (ISO)
Nutlin-3  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
octadecanoic acid  (ISO)
oleanolic acid  (ISO)
omeprazole  (EXP)
organoselenium compound  (ISO)
orlistat  (EXP)
p-chloromercuribenzoic acid  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (EXP)
peptidoglycan  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
peroxynitrous acid  (ISO)
phencyclidine  (ISO)
phenobarbital  (EXP)
phenylpropanolamine  (EXP)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphamidon  (ISO)
pirfenidone  (ISO)
pirinixic acid  (EXP)
porphyrins  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
probucol  (EXP,ISO)
propanal  (ISO)
prostaglandin E2  (ISO)
prostaglandin F2alpha  (ISO)
pterostilbene  (ISO)
Pyridostigmine bromide  (ISO)
pyrimethanil  (ISO)
quercetin  (EXP,ISO)
raspberry ketone  (ISO)
reactive oxygen species  (EXP,ISO)
resolvin D1  (ISO)
resveratrol  (EXP,ISO)
rosmarinic acid  (ISO)
rotenone  (EXP,ISO)
rutin  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenic acid  (ISO)
selenium atom  (EXP,ISO)
selenomethionine  (EXP,ISO)
silicic acid  (ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silver(1+) nitrate  (ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (ISO)
sulfur dioxide  (ISO)
T-2 toxin  (EXP,ISO)
tamibarotene  (ISO)
tert-butyl ethyl ether  (EXP)
tert-butyl hydroperoxide  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thalidomide  (EXP)
theophylline  (EXP)
thiacloprid  (EXP)
thioacetamide  (EXP,ISO)
thiomalic acid  (ISO)
thymoquinone  (EXP)
thyroxine  (EXP)
titanium atom  (ISO)
titanium dioxide  (EXP)
tributyl phosphate  (EXP)
Tributyltin oxide  (EXP)
triclosan  (ISO)
trilobatin  (EXP)
triolein  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (EXP,ISO)
tris(2-butoxyethyl) phosphate  (EXP,ISO)
tris(2-chloroethyl) phosphate  (ISO)
troglitazone  (EXP,ISO)
uranium atom  (EXP,ISO)
usnic acid  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (EXP)
vitamin E  (EXP,ISO)
water  (ISO)
zearalenone  (EXP)
zerumbone  (ISO)
zinc acetate  (ISO)
zinc atom  (EXP)
zinc pyrithione  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (IEP)
angiogenesis involved in wound healing  (IEA,ISO)
apoptotic process  (ISO)
arachidonic acid metabolic process  (IEA,ISO,ISS)
biological process involved in interaction with symbiont  (IEA,ISO)
blood vessel endothelial cell migration  (IEA,ISO)
cell population proliferation  (ISO)
cell redox homeostasis  (IEA,ISO)
cellular oxidant detoxification  (IEA)
cellular response to glucose stimulus  (IDA)
endothelial cell development  (IEA,ISO)
fat cell differentiation  (IEA,ISO)
glutathione metabolic process  (IBA,IDA,IEA,ISO)
heart contraction  (IEA,ISO)
hydrogen peroxide catabolic process  (IBA,IDA,IEA,ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (IEA,ISO)
lipid metabolic process  (ISO)
lipoxygenase pathway  (IEA,ISO,ISS)
myoblast proliferation  (IEA,ISO)
myotube differentiation  (ISO)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
negative regulation of inflammatory response to antigenic stimulus  (IEA,ISO)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway  (IEA,ISO)
negative regulation of release of cytochrome c from mitochondria  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
positive regulation of protein kinase B signaling  (IEA,ISO)
protein oxidation  (IEA,ISO)
regulation of gene expression, epigenetic  (IEA,ISO)
regulation of mammary gland epithelial cell proliferation  (IEA,ISO)
regulation of proteasomal protein catabolic process  (IEA,ISO)
response to estradiol  (IEP)
response to folic acid  (IEP)
response to gamma radiation  (IEA,ISO)
response to glucose  (IEP)
response to hormone  (IEP)
response to hydrogen peroxide  (IBA,IEA,ISO)
response to hydroperoxide  (IEA,ISO)
response to nicotine  (IEP)
response to organic cyclic compound  (IEP)
response to oxidative stress  (ISO)
response to reactive oxygen species  (ISO)
response to selenium ion  (IBA,IEA,IEP,ISO)
response to symbiotic bacterium  (IEA,ISO)
response to toxic substance  (ISO)
response to wounding  (ISO)
response to xenobiotic stimulus  (IEA,ISO)
sensory perception of sound  (IEA,ISO)
skeletal muscle fiber development  (IEA,ISO)
skeletal muscle tissue regeneration  (IEA,ISO)
temperature homeostasis  (IEA,ISO)
triglyceride metabolic process  (IEA,ISO)
UV protection  (IEA,ISO)
vasodilation  (IEA,ISO)

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,IDA)
Lewy body  (IEA,ISO)
mitochondrion  (IBA,IDA,IEA,ISO)
nucleus  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylsalicylic acid pharmacodynamics pathway  (ISO)
amyotrophic lateral sclerosis pathway  (IEA)
antipyrine drug pathway  (ISO)
arachidonic acid metabolic pathway  (IEA,ISO)
celecoxib pharmacodynamics pathway  (ISO)
diclofenac pharmacodynamics pathway  (ISO)
diflunisal pharmacodynamics pathway  (ISO)
etodolac pharmacodynamics pathway  (ISO)
fenoprofen pharmacodynamics pathway  (ISO)
flurbiprofen pharmacodynamics pathway  (ISO)
glutathione metabolic pathway  (IEA,ISO)
glutathione synthase deficiency pathway  (ISO)
glutathionuria disease pathway  (ISO)
Huntington's disease pathway  (IEA)
ibuprofen pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
ketoprofen pharmacodynamics pathway  (ISO)
ketorolac pharmacodynamics pathway  (ISO)
leukotriene C4 synthase deficiency pathway  (ISO)
lornoxicam pharmacodynamics pathway  (ISO)
magnesium salicylate pharmacodynamics pathway  (ISO)
mefenamic acid pharmacodynamics pathway  (ISO)
meloxicam pharmacodynamics pathway  (ISO)
nabumetone pharmacodynamics pathway  (ISO)
naproxen pharmacodynamics pathway  (ISO)
paracetamol drug pathway  (ISO)
piroxicam pharmacodynamics pathway  (ISO)
salicylic acid pharmacodynamics pathway  (ISO)
sodium salicylate pharmacodynamics pathway  (ISO)
sulindac pharmacodynamics pathway  (ISO)
tenoxicam pharmacodynamics pathway  (ISO)
tiaprofenic acid pharmacodynamics pathway  (ISO)
tolmetin pharmacodynamics pathway  (ISO)
valdecoxib pharmacodynamics pathway  (ISO)

References

References - curated
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Additional References at PubMed
PMID:6217842   PMID:8889548   PMID:9126277   PMID:9386101   PMID:9788901   PMID:10428770   PMID:10490281   PMID:10627575   PMID:10754271   PMID:10833429   PMID:10915565   PMID:10915653  
PMID:11115402   PMID:11311045   PMID:11518697   PMID:11545230   PMID:11562367   PMID:11579147   PMID:11893559   PMID:12117267   PMID:12196344   PMID:12221075   PMID:12368211   PMID:12477932  
PMID:12521604   PMID:12646716   PMID:12751788   PMID:12751789   PMID:12810669   PMID:12829378   PMID:12893824   PMID:14651853   PMID:14713308   PMID:14732290   PMID:15182862   PMID:15203190  
PMID:15663476   PMID:15777843   PMID:15821744   PMID:15827346   PMID:16132718   PMID:16189290   PMID:16229841   PMID:16373599   PMID:16723478   PMID:16934683   PMID:16945136   PMID:16962942  
PMID:17097614   PMID:17145560   PMID:18226427   PMID:18267129   PMID:18614015   PMID:18853169   PMID:19398061   PMID:19855070   PMID:20063054   PMID:20524817   PMID:22614831   PMID:22905402  
PMID:22981416   PMID:23376485   PMID:23472740   PMID:23911387   PMID:24389817   PMID:24401635   PMID:24740756   PMID:24867493   PMID:24962481   PMID:26142204   PMID:28755400   PMID:29016640  


Genomics

Comparative Map Data
Gpx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28109,026,905 - 109,028,031 (+)NCBI
Rnor_6.0 Ensembl8117,117,430 - 117,118,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08117,117,430 - 117,118,528 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,466,118 - 116,467,216 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,329,847 - 108,330,945 (+)ENTREZGENECelera
Cytogenetic Map8q32NCBI
GPX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,357,176 - 49,358,353 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,357,176 - 49,358,353 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,394,609 - 49,395,786 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,369,613 - 49,370,795 (-)NCBINCBI36hg18NCBI36
Build 34349,369,614 - 49,370,795NCBI
Celera349,359,484 - 49,360,663 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,454,091 - 49,455,270 (-)NCBIHuRef
CHM1_1349,347,422 - 49,348,601 (-)NCBICHM1_1
Gpx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,216,279 - 108,217,541 (+)NCBIGRCm39mm39
GRCm39 Ensembl9108,216,102 - 108,217,542 (+)Ensembl
GRCm389108,339,080 - 108,340,342 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,338,903 - 108,340,343 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,241,607 - 108,242,671 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,197,368 - 108,198,432 (+)NCBImm8
Celera9107,948,378 - 107,949,442 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.24NCBI
Gpx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555321,298,336 - 1,298,830 (-)NCBIChiLan1.0ChiLan1.0
GPX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,360,736 - 50,362,274 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,360,947 - 50,361,826 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,280,038 - 49,281,455 (-)NCBIMhudiblu_PPA_v0panPan3
GPX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,889,165 - 39,890,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,889,174 - 39,890,260 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2039,807,516 - 39,808,604 (+)NCBI
ROS_Cfam_1.02040,245,494 - 40,246,582 (+)NCBI
UMICH_Zoey_3.12039,612,973 - 39,614,061 (+)NCBI
UNSW_CanFamBas_1.02040,016,432 - 40,017,520 (+)NCBI
UU_Cfam_GSD_1.02040,296,220 - 40,297,308 (+)NCBI
Gpx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560264,237,446 - 64,238,592 (-)NCBI
SpeTri2.0NW_004936529997,943 - 999,123 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,914,932 - 31,917,335 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,916,269 - 31,917,337 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,147,277 - 35,148,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,754,976 - 10,756,617 (-)NCBI
Vero_WHO_p1.0NW_023666041156,259,200 - 156,261,033 (+)NCBI
Gpx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,313,773 - 3,314,870 (-)NCBI

Position Markers
PMC302051P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,027,242 - 109,027,461 (+)MAPPER
Rnor_6.08117,117,741 - 117,117,959NCBIRnor6.0
Rnor_5.08116,466,429 - 116,466,647UniSTSRnor5.0
Celera8108,330,158 - 108,330,376UniSTS
PMC305564P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,026,997 - 109,027,817 (+)MAPPER
Rnor_6.08117,117,496 - 117,118,315NCBIRnor6.0
Rnor_5.08116,466,184 - 116,467,003UniSTSRnor5.0
Celera8108,329,913 - 108,330,732UniSTS
WI-18922  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,025,491 - 109,025,637 (+)MAPPER
Rnor_6.08117,115,990 - 117,116,135NCBIRnor6.0
Rnor_5.08116,464,678 - 116,464,823UniSTSRnor5.0
Celera8108,328,407 - 108,328,552UniSTS
Cytogenetic Map16q12.5UniSTS
RH127950  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,027,817 - 109,028,004 (+)MAPPER
Rnor_6.08117,118,316 - 117,118,502NCBIRnor6.0
Rnor_5.08116,467,004 - 116,467,190UniSTSRnor5.0
Celera8108,330,733 - 108,330,919UniSTS
RH 3.4 Map81118.6UniSTS
RH129553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,027,823 - 109,028,011 (+)MAPPER
Rnor_6.08117,118,322 - 117,118,509NCBIRnor6.0
Rnor_5.08116,467,010 - 116,467,197UniSTSRnor5.0
Celera8108,330,739 - 108,330,926UniSTS
RH 3.4 Map81120.9UniSTS
AI195024  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,027,572 - 109,027,660 (+)MAPPER
Rnor_6.08117,118,071 - 117,118,158NCBIRnor6.0
Rnor_5.08116,466,759 - 116,466,846UniSTSRnor5.0
Celera8108,330,488 - 108,330,575UniSTS
PMC164851P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,027,109 - 109,027,605 (+)MAPPER
Rnor_6.08117,117,608 - 117,118,103NCBIRnor6.0
Rnor_5.08116,466,296 - 116,466,791UniSTSRnor5.0
Celera8108,330,025 - 108,330,520UniSTS
D3S1330E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,025,162 - 109,025,271 (+)MAPPER
Rnor_6.08117,115,661 - 117,115,769NCBIRnor6.0
Rnor_5.08116,464,349 - 116,464,457UniSTSRnor5.0
Celera8108,328,078 - 108,328,186UniSTS
Cytogenetic Map16q12.5UniSTS
UniSTS:532286  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,025,304 - 109,025,687 (+)MAPPER
Rnor_6.08117,115,803 - 117,116,185NCBIRnor6.0
Rnor_5.08116,464,491 - 116,464,873UniSTSRnor5.0
Celera8108,328,220 - 108,328,602UniSTS
Cytogenetic Map16q12.5UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)89531047119211942Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810938911120496129Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)844458129118087517Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)850529480128036471Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)865717449128033050Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)872849686117849686Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)874917593121080545Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)876103982127182642Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)878805083123805083Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)878805083123805083Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)878805083123805083Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)878805083123805083Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)880697934125697934Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)883894304128894304Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)889058229132243842Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)895963141122354314Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8100873811133307652Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8100873811133307652Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102051964133307652Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8104682575133307652Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)8104682575133307652Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8107769005129956433Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:33
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000073247
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 30 30 5 24 1
Medium 3 41 33 17 14 17 8 11 74 34 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB004231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI281978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB579218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ139913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M21210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S50336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000073247   ⟹   ENSRNOP00000066577
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl8117,117,430 - 117,118,522 (+)Ensembl
RefSeq Acc Id: NM_030826   ⟹   NP_110453
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28109,026,905 - 109,028,031 (+)NCBI
Rnor_6.08117,117,430 - 117,118,528 (+)NCBI
Rnor_5.08116,466,118 - 116,467,216 (+)NCBI
Celera8108,329,847 - 108,330,945 (+)ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_110453 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA12407 (Get FASTA)   NCBI Sequence Viewer  
  AAB95647 (Get FASTA)   NCBI Sequence Viewer  
  AAH58438 (Get FASTA)   NCBI Sequence Viewer  
  BAA20399 (Get FASTA)   NCBI Sequence Viewer  
  P04041 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_110453   ⟸   NM_030826
- UniProtKB: P04041 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066577   ⟸   ENSRNOT00000073247

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696297
Promoter ID:EPDNEW_R6821
Type:initiation region
Name:Gpx1_1
Description:glutathione peroxidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,117,462 - 117,117,522EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000