Parp2 (poly (ADP-ribose) polymerase 2) - Rat Genome Database

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Gene: Parp2 (poly (ADP-ribose) polymerase 2) Rattus norvegicus
Analyze
Symbol: Parp2
Name: poly (ADP-ribose) polymerase 2
RGD ID: 1310568
Description: Predicted to enable several functions, including nucleosome binding activity; pentosyltransferase activity; and poly-ADP-D-ribose binding activity. Involved in negative regulation of neuron death and positive regulation of cell growth involved in cardiac muscle cell development. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in site of DNA damage. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; base excision repair pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; Adprtl2; LOC290027; poly (ADP-ribose) polymerase family, member 2; poly [ADP-ribose] polymerase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21524,034,069 - 24,044,340 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,034,106 - 24,044,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,805,300 - 26,815,532 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01527,764,036 - 27,774,257 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01526,013,838 - 26,024,070 (+)NCBIRnor_WKY
Rnor_6.01527,739,416 - 27,749,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,739,251 - 27,749,648 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,571,841 - 31,582,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,790,296 - 26,801,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,806,027 - 26,816,785 (+)NCBI
Celera1524,353,597 - 24,363,829 (+)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation. Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. PARP-2 knockdown protects cardiomyocytes from hypertrophy via activation of SIRT1. Geng B, etal., Biochem Biophys Res Commun. 2013 Jan 18;430(3):944-50. doi: 10.1016/j.bbrc.2012.11.132. Epub 2012 Dec 19.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Moroni F, etal., Br J Pharmacol. 2009 Jul;157(5):854-62. doi: 10.1111/j.1476-5381.2009.00232.x. Epub 2009 May 5.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1. Zhang L, etal., Eur J Pharmacol. 2014 Dec 5;744:203-10. doi: 10.1016/j.ejphar.2014.09.037. Epub 2014 Sep 30.
Additional References at PubMed
PMID:10364231   PMID:11948190   PMID:12065591   PMID:12477932   PMID:15615785   PMID:25043379   PMID:27471034   PMID:28190768   PMID:30077797   PMID:30541899  


Genomics

Comparative Map Data
Parp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21524,034,069 - 24,044,340 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,034,106 - 24,044,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,805,300 - 26,815,532 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01527,764,036 - 27,774,257 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01526,013,838 - 26,024,070 (+)NCBIRnor_WKY
Rnor_6.01527,739,416 - 27,749,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,739,251 - 27,749,648 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,571,841 - 31,582,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,790,296 - 26,801,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,806,027 - 26,816,785 (+)NCBI
Celera1524,353,597 - 24,363,829 (+)NCBICelera
Cytogenetic Map15p14NCBI
PARP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,343,635 - 20,357,904 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1420,343,615 - 20,357,904 (+)EnsemblGRCh38hg38GRCh38
GRCh371420,811,794 - 20,826,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,881,613 - 19,895,903 (+)NCBINCBI36Build 36hg18NCBI36
Celera14672,919 - 687,220 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef14933,616 - 947,915 (+)NCBIHuRef
CHM1_11420,813,199 - 20,827,472 (+)NCBICHM1_1
T2T-CHM13v2.01414,540,530 - 14,554,811 (+)NCBIT2T-CHM13v2.0
Parp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,045,347 - 51,058,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,045,298 - 51,058,758 (+)EnsemblGRCm39 Ensembl
GRCm381450,807,897 - 50,821,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,807,841 - 50,821,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371451,427,621 - 51,440,975 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,729,897 - 49,743,251 (+)NCBIMGSCv36mm8
Celera1447,099,033 - 47,112,197 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.25NCBI
Parp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,140,460 - 1,151,491 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,138,976 - 1,152,293 (+)NCBIChiLan1.0ChiLan1.0
PARP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11419,268,986 - 19,282,960 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,269,046 - 19,282,853 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0141,215,727 - 1,230,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PARP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,705,966 - 17,716,743 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,705,975 - 17,716,094 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,191,050 - 18,201,770 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01517,964,896 - 17,975,837 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1517,964,862 - 17,975,138 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,647,938 - 17,657,915 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,702,653 - 17,713,344 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,831,425 - 17,842,255 (+)NCBIUU_Cfam_GSD_1.0
Parp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864077,573,779 - 77,583,748 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936877554,473 - 564,903 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936877554,969 - 564,905 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,535,076 - 78,551,375 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,535,072 - 78,551,393 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,563,415 - 83,579,720 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PARP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12920,862,787 - 20,877,752 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2920,863,380 - 20,877,644 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,544,206 - 25,558,652 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248254,313,217 - 4,325,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248254,312,243 - 4,326,058 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Parp2
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:66
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000011840
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat

Markers in Region
UniSTS:492996  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21524,033,659 - 24,033,963 (+)MAPPERmRatBN7.2
Rnor_6.01527,738,970 - 27,739,273NCBIRnor6.0
Rnor_5.01531,571,395 - 31,571,698UniSTSRnor5.0
RGSC_v3.41526,789,850 - 26,790,153UniSTSRGSC3.4
Celera1524,353,151 - 24,353,454UniSTS
Cytogenetic Map15p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 45 29 19 29 68 33 41 11
Low 15 12 12 12 8 11 6 2 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011840   ⟹   ENSRNOP00000011840
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1524,034,106 - 24,044,338 (+)Ensembl
Rnor_6.0 Ensembl1527,739,251 - 27,749,648 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105596   ⟹   ENSRNOP00000076757
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1524,035,238 - 24,041,402 (+)Ensembl
RefSeq Acc Id: NM_001106030   ⟹   NP_001099500
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,034,106 - 24,044,338 (+)NCBI
Rnor_6.01527,739,416 - 27,749,648 (+)NCBI
Rnor_5.01531,571,841 - 31,582,075 (+)NCBI
RGSC_v3.41526,790,296 - 26,801,086 (+)RGD
Celera1524,353,597 - 24,363,829 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251856   ⟹   XP_006251918
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,035,606 - 24,044,340 (+)NCBI
Rnor_6.01527,742,063 - 27,749,650 (+)NCBI
Rnor_5.01531,571,841 - 31,582,075 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093103   ⟹   XP_038949031
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,034,069 - 24,044,340 (+)NCBI
RefSeq Acc Id: XM_039093104   ⟹   XP_038949032
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,038,927 - 24,044,340 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001099500   ⟸   NM_001106030
- UniProtKB: G3V749 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251918   ⟸   XM_006251856
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000011840   ⟸   ENSRNOT00000011840
RefSeq Acc Id: XP_038949031   ⟸   XM_039093103
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949032   ⟸   XM_039093104
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000076757   ⟸   ENSRNOT00000105596
Protein Domains
PARP alpha-helical   PARP catalytic   WGR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V749-F1-model_v2 AlphaFold G3V749 1-558 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699622
Promoter ID:EPDNEW_R10144
Type:multiple initiation site
Name:Parp2_1
Description:poly (ADP-ribose) polymerase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01527,739,427 - 27,739,487EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310568 AgrOrtholog
BioCyc Gene G2FUF-14057 BioCyc
Ensembl Genes ENSRNOG00000008892 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011840 ENTREZGENE
  ENSRNOP00000011840.5 UniProtKB/TrEMBL
  ENSRNOP00000076757.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011840 ENTREZGENE
  ENSRNOT00000011840.7 UniProtKB/TrEMBL
  ENSRNOT00000105596.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.142.10 UniProtKB/TrEMBL
InterPro Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_reg_dom UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_reg_dom_sf UniProtKB/TrEMBL
  WGR_dom_sf UniProtKB/TrEMBL
  WGR_domain UniProtKB/TrEMBL
KEGG Report rno:290027 UniProtKB/TrEMBL
NCBI Gene 290027 ENTREZGENE
Pfam PARP UniProtKB/TrEMBL
  PARP_reg UniProtKB/TrEMBL
  WGR UniProtKB/TrEMBL
PhenoGen Parp2 PhenoGen
PROSITE PARP_ALPHA_HD UniProtKB/TrEMBL
  PARP_CATALYTIC UniProtKB/TrEMBL
  WGR UniProtKB/TrEMBL
SMART WGR UniProtKB/TrEMBL
Superfamily-SCOP PARP_reg UniProtKB/TrEMBL
  SSF142921 UniProtKB/TrEMBL
UniProt A0A8I5Y6B5_RAT UniProtKB/TrEMBL
  B1WC20_RAT UniProtKB/TrEMBL
  G3V749 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-17 Parp2  poly (ADP-ribose) polymerase 2  Parp2  poly (ADP-ribose) polymerase family, member 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Parp2  poly (ADP-ribose) polymerase family, member 2   Parp2_predicted  poly (ADP-ribose) polymerase family, member 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Parp2_predicted  poly (ADP-ribose) polymerase family, member 2 (predicted)  Adprtl2_predicted  ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Adprtl2_predicted  ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED