Tfec (transcription factor EC) - Rat Genome Database

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Gene: Tfec (transcription factor EC) Rattus norvegicus
Analyze
Symbol: Tfec
Name: transcription factor EC
RGD ID: 3846
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TFEC (transcription factor EC); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: rTFEC; Tcfec; TFE-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8446,072,093 - 46,146,200 (-)NCBIGRCr8
mRatBN7.2445,106,129 - 45,180,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl445,107,641 - 45,180,236 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx450,100,101 - 50,172,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0446,021,794 - 46,094,161 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0444,447,122 - 44,519,608 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0444,063,533 - 44,136,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl444,065,045 - 44,136,815 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0444,670,886 - 44,744,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4442,422,172 - 42,495,654 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1442,541,818 - 42,615,301 (-)NCBI
Celera440,398,740 - 40,470,786 (-)NCBICelera
RH 3.4 Map4258.81RGD
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. Zhao GQ, etal., Mol Cell Biol 1993 Aug;13(8):4505-12.
Additional References at PubMed
PMID:18755693  


Genomics

Comparative Map Data
Tfec
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8446,072,093 - 46,146,200 (-)NCBIGRCr8
mRatBN7.2445,106,129 - 45,180,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl445,107,641 - 45,180,236 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx450,100,101 - 50,172,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0446,021,794 - 46,094,161 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0444,447,122 - 44,519,608 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0444,063,533 - 44,136,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl444,065,045 - 44,136,815 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0444,670,886 - 44,744,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4442,422,172 - 42,495,654 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1442,541,818 - 42,615,301 (-)NCBI
Celera440,398,740 - 40,470,786 (-)NCBICelera
RH 3.4 Map4258.81RGD
Cytogenetic Map4q22NCBI
TFEC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387115,935,152 - 116,159,896 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7115,935,148 - 116,159,896 (-)EnsemblGRCh38hg38GRCh38
GRCh377115,575,206 - 115,670,817 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367115,362,438 - 115,458,034 (-)NCBINCBI36Build 36hg18NCBI36
Build 347115,173,976 - 115,264,746NCBI
Celera7110,382,578 - 110,478,171 (-)NCBICelera
Cytogenetic Map7q31.2NCBI
HuRef7109,941,132 - 110,036,927 (-)NCBIHuRef
CHM1_17115,508,483 - 115,604,121 (-)NCBICHM1_1
T2T-CHM13v2.07117,250,129 - 117,474,879 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27114,970,614 - 115,066,276 (-)NCBI
Tfec
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39616,830,926 - 16,898,463 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl616,833,372 - 16,898,440 (-)EnsemblGRCm39 Ensembl
GRCm38616,830,927 - 16,898,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl616,833,373 - 16,898,441 (-)EnsemblGRCm38mm10GRCm38
MGSCv37616,783,381 - 16,848,441 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36616,783,392 - 16,848,441 (-)NCBIMGSCv36mm8
Celera616,915,029 - 16,979,927 (-)NCBICelera
Cytogenetic Map6A2NCBI
cM Map67.61NCBI
Tfec
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543221,752,044 - 21,813,292 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543221,751,697 - 21,813,199 (-)NCBIChiLan1.0ChiLan1.0
TFEC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26152,760,399 - 152,937,498 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan174,770,655 - 4,947,754 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07107,900,876 - 107,996,752 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17120,598,588 - 120,823,338 (-)NCBIpanpan1.1PanPan1.1panPan2
TFEC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11454,977,603 - 55,194,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1454,979,110 - 55,105,323 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1454,368,445 - 54,589,602 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01455,011,659 - 55,232,717 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1455,016,421 - 55,192,923 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11455,043,051 - 55,264,294 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01454,731,988 - 54,953,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01455,102,571 - 55,323,323 (-)NCBIUU_Cfam_GSD_1.0
Tfec
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511843,684,480 - 43,749,006 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365892,971,417 - 3,000,694 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365892,971,350 - 3,001,480 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFEC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1830,122,494 - 30,175,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11829,980,394 - 30,260,226 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21832,094,390 - 32,287,701 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TFEC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12184,655,653 - 84,858,828 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2184,654,538 - 84,680,786 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604219,026,239 - 19,107,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfec
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248273,426,277 - 3,496,989 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248273,472,157 - 3,498,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tfec
295 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:182
Count of miRNA genes:128
Interacting mature miRNAs:142
Transcripts:ENSRNOT00000008156
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat

Markers in Region
RH94544  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2445,108,142 - 45,108,330 (+)MAPPERmRatBN7.2
Rnor_6.0444,065,547 - 44,065,734NCBIRnor6.0
Rnor_5.0444,672,900 - 44,673,087UniSTSRnor5.0
RGSC_v3.4442,422,674 - 42,422,861UniSTSRGSC3.4
Celera440,399,242 - 40,399,429UniSTS
RH 3.4 Map4258.81UniSTS
Cytogenetic Map4q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 9 15 1
Low 2 19 57 41 10 41 8 9 24 18 31 11 8
Below cutoff 1 20 1 49 2 9

Sequence


RefSeq Acc Id: ENSRNOT00000086810   ⟹   ENSRNOP00000073175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl445,107,641 - 45,180,236 (-)Ensembl
Rnor_6.0 Ensembl444,065,045 - 44,136,815 (-)Ensembl
RefSeq Acc Id: NM_022379   ⟹   NP_071774
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8446,073,605 - 46,146,200 (-)NCBI
mRatBN7.2445,107,641 - 45,180,236 (-)NCBI
Rnor_6.0444,065,045 - 44,136,815 (-)NCBI
Rnor_5.0444,670,886 - 44,744,984 (-)NCBI
RGSC_v3.4442,422,172 - 42,495,654 (-)RGD
Celera440,398,740 - 40,470,786 (-)RGD
Sequence:
RefSeq Acc Id: XM_006236128   ⟹   XP_006236190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8446,072,093 - 46,105,600 (-)NCBI
mRatBN7.2445,106,129 - 45,139,671 (-)NCBI
Rnor_6.0444,063,533 - 44,096,185 (-)NCBI
Rnor_5.0444,670,886 - 44,744,984 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_071774 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236190 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41523 (Get FASTA)   NCBI Sequence Viewer  
  EDM15100 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073175
  ENSRNOP00000073175.1
  ENSRNOP00055024537
  ENSRNOP00060000296
  ENSRNOP00065008839
GenBank Protein Q63302 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071774   ⟸   NM_022379
- UniProtKB: Q63302 (UniProtKB/Swiss-Prot),   A6IE13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236190   ⟸   XM_006236128
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000073175   ⟸   ENSRNOT00000086810
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63302-F1-model_v2 AlphaFold Q63302 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692889
Promoter ID:EPDNEW_R3413
Type:initiation region
Name:Tfec_1
Description:transcription factor EC
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0444,136,826 - 44,136,886EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3846 AgrOrtholog
BioCyc Gene G2FUF-45586 BioCyc
Ensembl Genes ENSRNOG00000061595 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055017991 UniProtKB/Swiss-Prot
  ENSRNOG00060000796 UniProtKB/Swiss-Prot
  ENSRNOG00065007741 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000086810 ENTREZGENE
  ENSRNOT00000086810.2 UniProtKB/Swiss-Prot
  ENSRNOT00055030484 UniProtKB/Swiss-Prot
  ENSRNOT00060000974 UniProtKB/Swiss-Prot
  ENSRNOT00065012110 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MiT/TFE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:26296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene Tfec ENTREZGENE
PANTHER MIP04163P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45776:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF3371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tfec PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000061595 RatGTEx
  ENSRNOG00055017991 RatGTEx
  ENSRNOG00060000796 RatGTEx
  ENSRNOG00065007741 RatGTEx
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP HLH, helix-loop-helix DNA-binding domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6IE13 ENTREZGENE, UniProtKB/TrEMBL
  Q63302 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tfec  transcription factor EC  Tcfec  transcription factor EC  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Tcfec  transcription factor EC  Tfec  transcription factor EC  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Tfec  transcription factor EC      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer 70037