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Gene: Slc7a5 (solute carrier family 7 member 5) Rattus norvegicus
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Symbol: Slc7a5
Name: solute carrier family 7 member 5
Description: Predicted to have L-leucine transmembrane transporter activity; L-tryptophan transmembrane transporter activity; and peptide antigen binding activity. Predicted to be involved in L-tryptophan transmembrane transport and neutral amino acid transport. Localizes to the basal plasma membrane and external side of apical plasma membrane. Orthologous to human SLC7A5 (solute carrier family 7 member 5); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4F2 LC; 4F2 light chain; 4F2LC; E16; integral membrane protein E16; L-type amino acid transporter 1; large neutral amino acids transporter small subunit 1; LAT-1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; TA1; TA1/LAT-1/CD98 light chain region; tumor-associated protein 1
Orthologs:
Homo sapiens (human) : SLC7A5 (solute carrier family 7 member 5)  HGNC  Alliance
Mus musculus (house mouse) : Slc7a5 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc7a5 (solute carrier family 7 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A5 (solute carrier family 7 member 5)
Canis lupus familiaris (dog) : SLC7A5 (solute carrier family 7 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a5 (solute carrier family 7 member 5)
Sus scrofa (pig) : SLC7A5 (solute carrier family 7 member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01954,693,959 - 54,722,563 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1954,693,959 - 54,722,563 (-)Ensembl
Rnor_5.01965,412,970 - 65,441,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,120,728 - 52,149,332 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,125,608 - 52,154,213 (-)NCBI
Celera1949,180,586 - 49,208,780 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc7a5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620639
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.