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Gene: Slc7a5 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 5) Mus musculus
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Symbol: Slc7a5
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Description: Exhibits L-amino acid transmembrane transporter activity. Involved in L-amino acid transport. Predicted to localize to several cellular components, including amino acid transport complex; basal plasma membrane; and external side of apical plasma membrane. Is expressed in several structures, including central nervous system; cochlea; early conceptus; incisor; and limb. Used to study autism spectrum disorder. Orthologous to human SLC7A5 (solute carrier family 7 member 5); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4F2 LC; 4F2 light chain; 4F2LC; D0H16S474E; Gm42049; L-type amino acid transporter 1; large neutral amino acids transporter small subunit 1; LAT1; solute carrier family 7 member 5; TA1
Orthologs:
Homo sapiens (human) : SLC7A5 (solute carrier family 7 member 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc7a5 (solute carrier family 7 member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc7a5 (solute carrier family 7 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A5 (solute carrier family 7 member 5)
Canis lupus familiaris (dog) : SLC7A5 (solute carrier family 7 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a5 (solute carrier family 7 member 5)
Sus scrofa (pig) : SLC7A5 (solute carrier family 7 member 5)
Chlorocebus sabaeus (African green monkey) : SLC7A5 (solute carrier family 7 member 5)
Heterocephalus glaber (naked mole-rat) : Slc7a5 (solute carrier family 7 member 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl8121,881,150 - 121,907,694 (-)EnsemblGRCm38mm10GRCm38
GRCm388121,881,146 - 121,907,686 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378124,405,046 - 124,431,586 (-)NCBIGRCm37mm9NCBIm37
MGSCv368121,952,557 - 121,979,440 (-)NCBImm8
MGSCv368124,767,240 - 124,802,593 (-)NCBImm8
Celera8126,102,885 - 126,145,803 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc7a5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733672
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.