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Gene: Slc7a5 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 5) Mus musculus
Symbol: Slc7a5
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Description: Exhibits L-amino acid transmembrane transporter activity. Involved in L-amino acid transport. Predicted to localize to several cellular components, including amino acid transport complex; basal plasma membrane; and external side of apical plasma membrane. Is expressed in several structures, including central nervous system; cochlea; early conceptus; incisor; and limb. Used to study autism spectrum disorder. Orthologous to human SLC7A5 (solute carrier family 7 member 5); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4F2 LC; 4F2 light chain; 4F2LC; D0H16S474E; Gm42049; L-type amino acid transporter 1; large neutral amino acids transporter small subunit 1; LAT1; solute carrier family 7 member 5; TA1
Homo sapiens (human) : SLC7A5 (solute carrier family 7 member 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc7a5 (solute carrier family 7 member 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc7a5 (solute carrier family 7 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A5 (solute carrier family 7 member 5)
Canis lupus familiaris (dog) : SLC7A5 (solute carrier family 7 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a5 (solute carrier family 7 member 5)
Sus scrofa (pig) : SLC7A5 (solute carrier family 7 member 5)
Chlorocebus sabaeus (African green monkey) : SLC7A5 (solute carrier family 7 member 5)
Heterocephalus glaber (naked mole-rat) : Slc7a5 (solute carrier family 7 member 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl8121,881,150 - 121,907,694 (-)EnsemblGRCm38mm10GRCm38
GRCm388121,881,146 - 121,907,686 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378124,405,046 - 124,431,586 (-)NCBIGRCm37mm9NCBIm37
MGSCv368121,952,557 - 121,979,440 (-)NCBImm8
MGSCv368124,767,240 - 124,802,593 (-)NCBImm8
Celera8126,102,885 - 126,145,803 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc7a5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733672
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.