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Gene: Akt1s1 (AKT1 substrate 1) Rattus norvegicus
Symbol: Akt1s1
Name: AKT1 substrate 1
RGD ID: 1312049
Description: Predicted to be involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Localizes to cytoplasm; nucleus; and protein-containing complex. Predicted to colocalize with TORC1 complex. Orthologous to human AKT1S1 (AKT1 substrate 1); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AKT1 substrate 1 (proline-rich); LOC292887; PKB/Akt substrate 40; PRAS40; proline-rich AKT1 substrate 1
Homo sapiens (human) : AKT1S1 (AKT1 substrate 1)  HGNC  Alliance
Mus musculus (house mouse) : Akt1s1 (AKT1 substrate 1 (proline-rich))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akt1s1 (AKT1 substrate 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKT1S1 (AKT1 substrate 1)
Canis lupus familiaris (dog) : AKT1S1 (AKT1 substrate 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akt1s1 (AKT1 substrate 1)
Sus scrofa (pig) : AKT1S1 (AKT1 substrate 1)
Chlorocebus sabaeus (African green monkey) : AKT1S1 (AKT1 substrate 1)
Heterocephalus glaber (naked mole-rat) : Akt1s1 (AKT1 substrate 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01100,845,443 - 100,851,961 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,845,563 - 100,851,960 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,910,233 - 101,916,583 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,325,272 - 95,328,510 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1195,400,788 - 95,405,932 (+)NCBI
Celera189,595,080 - 89,601,434 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Akt1s1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312049
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.