Gene: Cyp17a1 (cytochrome P450, family 17, subfamily a, polypeptide 1) Rattus norvegicus
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Description: ENCODES a protein that exhibits steroid 17-alpha-monooxygenase activity; 17-alpha-hydroxyprogesterone aldolase activity (ortholog); heme binding (ortholog); INVOLVED IN adrenal gland development; biphenyl metabolic process; cellular response to antibiotic; PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH Sciatic Neuropathy; 17,20-Lyase Deficiency, Isolated (ortholog); Adrenal Hyperplasia, Congenital (ortholog); FOUND IN cell projection; endoplasmic reticulum; intracellular membrane-bounded organelle; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3,4-oxadiazole
Type: protein-coding
Also known as: 17-alpha-hydroxyprogesterone aldolase; Cyp17; CYPXVII; cytochrome P450 17A1; Cytochrome P450 subfamily XVII; cytochrome P450, subfamily 17; Cytochrome P450, subfamily XVII; cytochrome P450-C17; cytochrome P450c17; P450-C17; P45017alpha; P450c17; steroid 17-alpha-hydroxylase/17,20 lyase
Homo sapiens (human) : CYP17A1 (cytochrome P450 family 17 subfamily A member 1)  HGNC  AGR
Mus musculus (house mouse) : Cyp17a1 (cytochrome P450, family 17, subfamily a, polypeptide 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : LOC102011010 (steroid 17-alpha-hydroxylase/17,20 lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100989182 (steroid 17-alpha-hydroxylase/17,20 lyase)
Canis lupus familiaris (dog) : CYP17A1 (cytochrome P450, family 17, subfamily A, polypeptide 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101970767 (steroid 17-alpha-hydroxylase/17,20 lyase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01266,422,127 - 266,429,947 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01273,852,163 - 273,859,866 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,965,458 - 251,971,449 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11252,228,608 - 252,234,604 (-)NCBI
Celera1241,321,307 - 241,327,254 (-)NCBICelera
Cytogenetic Map1q54NCBI
RH 3.4 Map11626.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp17a1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2456
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE