(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP17A1 mRNA] CTD PMID:31150632 (R,R)-tramadol decreases activity ISO RGD:1350540 6480464 Tramadol results in decreased activity of CYP17A1 protein CTD PMID:29100959 (S)-duloxetine hydrochloride decreases activity ISO RGD:1350540 6480464 Duloxetine Hydrochloride results in decreased activity of CYP17A1 protein CTD PMID:29100959 (S)-duloxetine hydrochloride multiple interactions ISO RGD:1350540 6480464 Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone] more ... CTD PMID:29100959 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of CYP17A1 mRNA, Nicotine results in decreased expression of CYP17A1 protein CTD PMID:27782041 , PMID:28986172 (S)-nicotine decreases expression ISO RGD:1350540 6480464 Nicotine results in decreased expression of CYP17A1 mRNA CTD PMID:24709674 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases expression ISO RGD:737222 6480464 2 more ... CTD PMID:11509743 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity EXP 6480464 2 more ... CTD PMID:24451217 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity ISO RGD:1350540 6480464 2 more ... CTD PMID:24451217 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:737222 6480464 [Estradiol co-treated with 2 more ... CTD PMID:11509743 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane decreases expression ISO RGD:737222 6480464 1 more ... CTD PMID:20840852 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of CYP17A1 mRNA CTD PMID:17984292 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO RGD:737222 6480464 o, p'-DDT affects the expression of CYP17A1 mRNA CTD PMID:18925944 1,2-dichloroethane affects expression ISO RGD:737222 6480464 ethylene dichloride affects the expression of CYP17A1 mRNA CTD PMID:28973639 1,3,4-oxadiazoles decreases activity EXP 6480464 1 more ... CTD PMID:25993309 1,3-dinitrobenzene decreases expression ISO RGD:1350540 6480464 3-dinitrobenzene results in decreased expression of CYP17A1 mRNA CTD PMID:22841810 17alpha-ethynylestradiol multiple interactions ISO RGD:1350540 6480464 [Ethinyl Estradiol co-treated with drospirenone] results in decreased activity of CYP17A1 protein CTD PMID:17418832 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of CYP17A1 mRNA CTD PMID:12655037 more ... 17alpha-ethynylestradiol increases expression ISO RGD:737222 6480464 Ethinyl Estradiol results in increased expression of CYP17A1 mRNA CTD PMID:12072388 17alpha-ethynylestradiol affects expression ISO RGD:737222 6480464 Ethinyl Estradiol affects the expression of CYP17A1 mRNA CTD PMID:14976129 17alpha-hydroxypregnenolone affects chemical synthesis ISO RGD:1350540 6480464 CYP17A1 protein affects the chemical synthesis of 17-alpha-Hydroxypregnenolone CTD PMID:16030167 17alpha-hydroxypregnenolone increases metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone CTD PMID:29100959 17alpha-hydroxypregnenolone multiple interactions ISO RGD:1350540 6480464 [[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone more ... CTD PMID:17194026 , PMID:29100959 17alpha-hydroxypregnenolone decreases acetylation ISO RGD:1350540 6480464 CYP17A1 protein results in decreased acetylation of 17-alpha-Hydroxypregnenolone CTD PMID:15562394 17alpha-hydroxypregnenolone affects metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein affects the metabolism of 17-alpha-Hydroxypregnenolone CTD PMID:16030167 17alpha-hydroxyprogesterone affects abundance ISO RGD:1350540 6480464 CYP17A1 protein affects the abundance of 17-alpha-Hydroxyprogesterone CTD PMID:21427057 17alpha-hydroxyprogesterone increases metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone CTD PMID:29100959 17alpha-hydroxyprogesterone multiple interactions ISO RGD:1350540 6480464 [[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone more ... CTD PMID:16030167 more ... 17alpha-hydroxyprogesterone affects metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein affects the metabolism of 17-alpha-Hydroxyprogesterone CTD PMID:16030167 17alpha-hydroxyprogesterone affects chemical synthesis ISO RGD:1350540 6480464 CYP17A1 protein affects the chemical synthesis of 17-alpha-Hydroxyprogesterone CTD PMID:16030167 17beta-estradiol multiple interactions ISO RGD:737222 6480464 [Estradiol co-treated with 2 more ... CTD PMID:11509743 more ... 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of CYP17A1 mRNA CTD PMID:26496021 17beta-estradiol increases expression ISO RGD:737222 6480464 Estradiol results in increased expression of CYP17A1 mRNA CTD PMID:18281260 more ... 17beta-estradiol decreases expression ISO RGD:737222 6480464 Estradiol results in decreased expression of CYP17A1 mRNA, Estradiol results in decreased expression of CYP17A1 protein CTD PMID:11509743 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of CYP17A1 mRNA, Estradiol results in decreased expression of CYP17A1 protein CTD PMID:20144698 17beta-estradiol 3-benzoate decreases expression EXP 6480464 estradiol 3-benzoate results in decreased expression of CYP17A1 protein CTD PMID:24752506 1H-pyrazole decreases expression ISO RGD:737222 6480464 pyrazole results in decreased expression of CYP17A1 mRNA CTD PMID:17945193 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:737222 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:1350540 6480464 2 more ... CTD PMID:18248924 2,2',4,4'-Tetrabromodiphenyl ether decreases activity ISO RGD:1350540 6480464 2 more ... CTD PMID:16828825 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:737222 6480464 [2 more ... CTD PMID:25510870 2,3,4,7,8-Pentachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,3,7,8-tetrabromodibenzodioxine decreases expression ISO RGD:1350540 6480464 2 more ... CTD PMID:17447562 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Gonadotropins, Equine inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP17A1 mRNA] CTD PMID:19276399 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:737222 6480464 Tetrachlorodibenzodioxin affects the expression of CYP17A1 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:737222 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP17A1 gene] CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737222 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP17A1 mRNA CTD PMID:19770486 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP17A1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of CYP17A1 protein CTD PMID:16254025 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP17A1 mRNA CTD PMID:20959002 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CYP17A1 mRNA CTD PMID:22298810 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,4,6-tribromophenol decreases expression ISO RGD:1350540 6480464 2 more ... CTD PMID:17447562 2,4-D affects expression ISO RGD:737222 6480464 2, 4-Dichlorophenoxyacetic Acid affects the expression of CYP17A1 mRNA CTD PMID:26838045 2,4-dibromophenol increases expression ISO RGD:1350540 6480464 2, 4-dibromophenol results in increased expression of CYP17A1 mRNA CTD PMID:17447562 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CYP17A1 mRNA CTD PMID:21346803 2,6-dibromophenol decreases expression ISO RGD:1350540 6480464 2, 6-dibromophenol results in decreased expression of CYP17A1 mRNA CTD PMID:17447562 2-bromophenol increases expression ISO RGD:1350540 6480464 2-bromophenol results in increased expression of CYP17A1 mRNA CTD PMID:17447562 2-methoxyethanol decreases expression EXP 6480464 methyl cellosolve results in decreased expression of CYP17A1 mRNA CTD PMID:21061450 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions EXP 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 2-trans,6-trans-farnesyl diphosphate multiple interactions EXP 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 3',5'-cyclic AMP multiple interactions ISO RGD:1350540 6480464 [acetyl methyl tetramethyl tetralin co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein more ... CTD PMID:23084589 3',5'-cyclic AMP increases expression ISO RGD:737222 6480464 Cyclic AMP results in increased expression of CYP17A1 mRNA CTD PMID:25576683 3,3',4,4',5-pentachlorobiphenyl decreases activity ISO RGD:1350540 6480464 3 more ... CTD PMID:15703266 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:1350540 6480464 3 more ... CTD PMID:16216300 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:1350540 6480464 3 more ... CTD PMID:15703266 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:737222 6480464 3 more ... CTD PMID:12781204 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:737222 6480464 tetrabromobisphenol A results in increased expression of CYP17A1 mRNA CTD PMID:24014645 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of CYP17A1 mRNA CTD PMID:26988606 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:737222 6480464 2 more ... CTD PMID:21726595 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol decreases expression ISO RGD:1350540 6480464 1H more ... CTD PMID:20615422 3alpha-hydroxy-5beta-pregnan-20-one increases hydroxylation ISO RGD:1350540 6480464 CYP17A1 protein results in increased hydroxylation of Pregnanolone analog CTD PMID:14522586 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of CYP17A1 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol increases expression ISO RGD:737222 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CYP17A1 mRNA CTD PMID:25576683 , PMID:30196065 4,4'-sulfonyldiphenol decreases expression ISO RGD:737222 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of CYP17A1 mRNA CTD PMID:31132128 4,4'-sulfonyldiphenol decreases expression ISO RGD:1350540 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of CYP17A1 mRNA CTD PMID:26751127 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile decreases activity ISO RGD:1350540 6480464 Fadrozole results in decreased activity of CYP17A1 protein CTD PMID:15743198 , PMID:15771425 4-nonylphenol multiple interactions ISO RGD:737222 6480464 [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA CTD PMID:29029336 4-nonylphenol decreases expression ISO RGD:737222 6480464 4-nonylphenol results in decreased expression of CYP17A1 mRNA CTD PMID:29029336 4-octylphenol decreases expression EXP 6480464 4-octylphenol results in decreased expression of CYP17A1 protein CTD PMID:9361775 4-tert-Octylphenol decreases expression ISO RGD:737222 6480464 4-tert-octylphenol results in decreased expression of CYP17A1 mRNA CTD PMID:17696135 4-tert-Octylphenol multiple interactions ISO RGD:737222 6480464 [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA CTD PMID:29029336 5alpha-pregnane-3,20-dione increases hydroxylation ISO RGD:1350540 6480464 CYP17A1 protein results in increased hydroxylation of 5-alpha-Dihydroprogesterone CTD PMID:14522586 8-bromo-3',5'-cyclic AMP multiple interactions ISO RGD:737222 6480464 2 more ... CTD PMID:21610156 , PMID:21726595 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:737222 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA, 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein CTD PMID:21726595 , PMID:24014645 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:1350540 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA CTD PMID:22079614 , PMID:22546480 8-bromo-3',5'-cyclic AMP multiple interactions ISO RGD:1350540 6480464 [4-nitro-3-phenylphenol co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in decreased expression of CYP17A1 protein, Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA] CTD PMID:18336853 , PMID:22546480 abiraterone decreases activity EXP 6480464 abiraterone results in decreased activity of CYP17A1 protein CTD PMID:25993309 abiraterone multiple interactions ISO RGD:1350540 6480464 [[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone more ... CTD PMID:29100959 abiraterone decreases activity ISO RGD:1350540 6480464 abiraterone analog results in decreased activity of CYP17A1 protein, abiraterone results in decreased activity of CYP17A1 protein CTD PMID:17194026 , PMID:29100959 acetaldehyde multiple interactions ISO RGD:737222 6480464 [CGA protein results in increased abundance of Acetaldehyde] which results in increased expression of CYP17A1 mRNA CTD PMID:22285649 aflatoxin B1 decreases expression ISO RGD:737222 6480464 Aflatoxin B1 results in decreased expression of CYP17A1 mRNA CTD PMID:19770486 albuterol increases expression ISO RGD:1350540 6480464 Albuterol results in increased expression of CYP17A1 CTD PMID:17822730 all-trans-retinoic acid increases expression ISO RGD:1350540 6480464 Tretinoin results in increased expression of CYP17A1 mRNA CTD PMID:16621909 all-trans-retinoic acid multiple interactions ISO RGD:737222 6480464 Tretinoin inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of CYP17A1 mRNA CTD PMID:14960491 alpha-naphthoflavone decreases expression ISO RGD:1350540 6480464 alpha-naphthoflavone results in decreased expression of CYP17A1 mRNA CTD PMID:24875446 alternariol increases expression ISO RGD:1350540 6480464 alternariol results in increased expression of CYP17A1 mRNA CTD PMID:23665424 aminoglutethimide decreases expression ISO RGD:1350540 6480464 Aminoglutethimide results in decreased expression of CYP17A1 mRNA CTD PMID:16935330 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CYP17A1 mRNA CTD PMID:16483693 androgen antagonist multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP17A1 mRNA, [Pesticides co-treated with Phthalic Acids co-treated with Androgen Antagonists] results in decreased expression of CYP17A1 mRNA CTD PMID:25607892 , PMID:29945228 andrographolide multiple interactions ISO RGD:737222 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CYP17A1 mRNA CTD PMID:19737545 androst-4-ene-3,17-dione decreases expression ISO RGD:1350540 6480464 Androstenedione results in decreased expression of CYP17A1 mRNA CTD PMID:15625562 androst-4-ene-3,17-dione affects chemical synthesis ISO RGD:737222 6480464 CYP17A1 protein affects the chemical synthesis of Androstenedione CTD PMID:15555913 androst-4-ene-3,17-dione multiple interactions ISO RGD:1350540 6480464 [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione more ... CTD PMID:16030167 , PMID:29100959 androst-4-ene-3,17-dione affects chemical synthesis ISO RGD:1350540 6480464 CYP17A1 protein affects the chemical synthesis of Androstenedione CTD PMID:14522586 more ... androst-4-ene-3,17-dione affects abundance ISO RGD:1350540 6480464 CYP17A1 protein affects the abundance of Androstenedione CTD PMID:21427057 androsterone affects chemical synthesis ISO RGD:1350540 6480464 CYP17A1 protein affects the chemical synthesis of Androsterone CTD PMID:14522586 antalarmin decreases expression ISO RGD:1350540 6480464 antalarmin results in decreased expression of CYP17A1 mRNA CTD PMID:16014403 anthra[1,9-cd]pyrazol-6(2H)-one increases expression ISO RGD:1350540 6480464 pyrazolanthrone results in increased expression of CYP17A1 mRNA CTD PMID:16269825 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA], pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] CTD PMID:29567110 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1350540 6480464 pyrazolanthrone inhibits the reaction [FGF19 protein results in decreased expression of CYP17A1 mRNA] CTD PMID:16269825 apigenin multiple interactions ISO RGD:1350540 6480464 Apigenin inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] CTD PMID:23370353 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP17A1 mRNA, Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP17A1 protein CTD PMID:29208485 arsane affects metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein affects the metabolism of Arsenic CTD PMID:18682255 arsenic atom affects metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein affects the metabolism of Arsenic CTD PMID:18682255 arsenous acid decreases expression ISO RGD:737222 6480464 Arsenic Trioxide results in decreased expression of CYP17A1 mRNA CTD PMID:18630931 astressin decreases expression ISO RGD:1350540 6480464 astressin results in decreased expression of CYP17A1 mRNA CTD PMID:16014403 atorvastatin calcium increases expression EXP 6480464 Atorvastatin results in increased expression of CYP17A1 mRNA CTD PMID:29574565 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of CYP17A1 mRNA CTD PMID:19541795 atrazine decreases expression ISO RGD:737222 6480464 Atrazine results in decreased expression of CYP17A1 mRNA CTD PMID:23376530 , PMID:23591565 atrazine increases expression EXP 6480464 Atrazine results in increased expression of CYP17A1 mRNA, Atrazine results in increased expression of CYP17A1 protein CTD PMID:20667998 , PMID:23200735 atrazine multiple interactions EXP 6480464 [Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA more ... CTD PMID:23200735 benomyl decreases expression ISO RGD:1350540 6480464 Benomyl results in decreased expression of CYP17A1 mRNA CTD PMID:25324206 benomyl multiple interactions ISO RGD:1350540 6480464 Benomyl results in decreased expression of and results in decreased activity of CYP17A1 protein CTD PMID:25324206 benzo[a]pyrene decreases expression ISO RGD:737222 6480464 Benzo(a)pyrene results in decreased expression of CYP17A1 mRNA CTD PMID:19770486 benzo[a]pyrene multiple interactions ISO RGD:737222 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CYP17A1 mRNA CTD PMID:27858113 benzo[a]pyrene affects expression EXP 6480464 Benzo(a)pyrene affects the expression of CYP17A1 mRNA CTD PMID:22960446 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of CYP17A1 mRNA, Benzo(a)pyrene results in decreased expression of CYP17A1 protein CTD PMID:21737371 benzo[b]fluoranthene multiple interactions ISO RGD:737222 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CYP17A1 mRNA CTD PMID:27858113 berberine multiple interactions ISO RGD:737222 6480464 Berberine inhibits the reaction [Dexamethasone results in increased expression of CYP17A1 mRNA] CTD PMID:20462044 beta-damascenone increases expression ISO RGD:737222 6480464 beta-damascenone results in increased expression of CYP17A1 mRNA CTD PMID:22982537 beta-naphthoflavone multiple interactions ISO RGD:737222 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CYP17A1 mRNA CTD PMID:19737545 bexarotene multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in increased expression of CYP17A1 mRNA CTD PMID:17630414 bifenthrin decreases expression ISO RGD:737222 6480464 bifenthrin results in decreased expression of CYP17A1 mRNA CTD PMID:23994515 , PMID:24449165 bifenthrin increases expression ISO RGD:1350540 6480464 bifenthrin results in increased expression of CYP17A1 mRNA CTD PMID:24938463 bifenthrin increases expression ISO RGD:737222 6480464 bifenthrin results in increased expression of CYP17A1 mRNA CTD PMID:26071804 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:737222 6480464 [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA CTD PMID:29029336 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Plant Extracts co-treated with Diethylhexyl Phthalate] affects the expression of CYP17A1 mRNA CTD PMID:29777495 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:26472102 more ... bis(2-ethylhexyl) phthalate decreases expression ISO RGD:737222 6480464 Diethylhexyl Phthalate results in decreased expression of CYP17A1 mRNA, Diethylhexyl Phthalate results in decreased expression of CYP17A1 protein CTD PMID:25701202 more ... bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP17A1 mRNA more ... CTD PMID:14605012 more ... bisphenol A multiple interactions ISO RGD:737222 6480464 bisphenol A promotes the reaction [Estradiol results in increased expression of CYP17A1 mRNA], bisphenol A promotes the reaction [Estradiol results in increased expression of CYP17A1 protein] CTD PMID:28476547 bisphenol A affects expression ISO RGD:737222 6480464 bisphenol A affects the expression of CYP17A1 mRNA, bisphenol A affects the expression of CYP17A1 protein CTD PMID:28476547 bisphenol A decreases expression ISO RGD:737222 6480464 bisphenol A results in decreased expression of CYP17A1 mRNA CTD PMID:21182934 more ... bisphenol A decreases expression ISO RGD:1350540 6480464 bisphenol A results in decreased expression of CYP17A1 mRNA CTD PMID:26751127 bisphenol A increases expression ISO RGD:737222 6480464 bisphenol A results in increased expression of CYP17A1 mRNA CTD PMID:17706920 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CYP17A1 mRNA, bisphenol A results in decreased expression of CYP17A1 protein CTD PMID:14605012 more ... bisphenol A decreases activity EXP 6480464 bisphenol A results in decreased activity of CYP17A1 protein CTD PMID:21925253 bisphenol A decreases activity ISO RGD:1350540 6480464 bisphenol A results in decreased activity of CYP17A1 protein CTD PMID:21427057 , PMID:21925253 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CYP17A1 mRNA, bisphenol A results in increased expression of CYP17A1 protein CTD PMID:18191889 , PMID:29524480 bisphenol F decreases expression ISO RGD:1350540 6480464 4, 4'-bisphenol F results in decreased expression of CYP17A1 mRNA CTD PMID:26751127 bisphenol F increases expression ISO RGD:737222 6480464 bisphenol F results in increased expression of CYP17A1 mRNA CTD PMID:30196065 bucladesine decreases expression EXP 6480464 Bucladesine results in decreased expression of CYP17A1 mRNA CTD PMID:21693180 bucladesine increases expression EXP 6480464 Bucladesine results in increased expression of CYP17A1 mRNA CTD PMID:21458522 bucladesine multiple interactions EXP 6480464 [Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA, Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA] CTD PMID:23200735 Butylbenzyl phthalate multiple interactions ISO RGD:737222 6480464 [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA CTD PMID:29029336 Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:26472102 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of CYP17A1 mRNA CTD PMID:19167457 cadmium dichloride decreases expression ISO RGD:737222 6480464 Cadmium Chloride results in decreased expression of CYP17A1 mRNA, Cadmium Chloride results in decreased expression of CYP17A1 protein CTD PMID:19897027 , PMID:24982889 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of CYP17A1 mRNA, Cadmium Chloride results in decreased expression of CYP17A1 protein CTD PMID:25993096 , PMID:29214744 caffeine increases expression EXP 6480464 Caffeine results in increased expression of CYP17A1 mRNA CTD PMID:25868845 carbamazepine decreases activity ISO RGD:1350540 6480464 Carbamazepine results in decreased activity of CYP17A1 protein CTD PMID:15730543 carbamazepine decreases expression ISO RGD:1350540 6480464 Carbamazepine results in decreased expression of CYP17A1 mRNA CTD PMID:19566492 carbon nanotube decreases expression ISO RGD:737222 6480464 Nanotubes, Carbon analog results in decreased expression of CYP17A1 mRNA, Nanotubes, Carbon results in decreased expression of CYP17A1 mRNA CTD PMID:25620056 cetrorelix multiple interactions ISO RGD:1350540 6480464 [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP17A1 mRNA, [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CYP17A1 mRNA CTD PMID:18160741 chenodeoxycholic acid decreases expression ISO RGD:737222 6480464 Chenodeoxycholic Acid results in decreased expression of CYP17A1 mRNA CTD PMID:22961653 chenodeoxycholic acid multiple interactions ISO RGD:737222 6480464 NR1H4 protein promotes the reaction [Chenodeoxycholic Acid results in decreased expression of CYP17A1 mRNA] CTD PMID:22961653 chloroquine decreases expression EXP 6480464 Chloroquine results in decreased expression of CYP17A1 mRNA CTD PMID:19393257 cholesterol affects chemical synthesis ISO RGD:737222 6480464 CYP17A1 protein affects the chemical synthesis of Cholesterol CTD PMID:15761033 Chorionic gonadotropin increases expression EXP 6480464 Chorionic Gonadotropin results in increased expression of CYP17A1 mRNA CTD PMID:15930178 Chorionic gonadotropin multiple interactions ISO RGD:1350540 6480464 [Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of CYP17A1 mRNA CTD PMID:28648634 chrysene multiple interactions ISO RGD:737222 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CYP17A1 mRNA CTD PMID:27858113 cinnamic acid decreases activity ISO RGD:1350540 6480464 cinnamic acid analog results in decreased activity of CYP17A1 protein CTD PMID:15072549 clofibrate multiple interactions ISO RGD:737222 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CYP17A1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP17A1 mRNA] CTD PMID:17585979 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of CYP17A1 mRNA CTD PMID:15033592 clofibrate decreases expression ISO RGD:737222 6480464 Clofibrate results in decreased expression of CYP17A1 mRNA CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP17A1 mRNA CTD PMID:17602206 Colforsin dapropate hydrochloride increases expression ISO RGD:1350540 6480464 Colforsin results in increased expression of CYP17A1 mRNA CTD PMID:15625562 more ... Colforsin dapropate hydrochloride increases expression ISO RGD:737222 6480464 Colforsin results in increased expression of CYP17A1 mRNA CTD PMID:22461451 Colforsin dapropate hydrochloride multiple interactions ISO RGD:1350540 6480464 Apigenin inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] more ... CTD PMID:15625562 more ... corticotropin affects abundance ISO RGD:1350540 6480464 CYP17A1 protein affects the abundance of Adrenocorticotropic Hormone CTD PMID:18645707 cyanamide multiple interactions ISO RGD:737222 6480464 Cyanamide inhibits the reaction [CGA protein results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 cyclosporin A decreases expression ISO RGD:737222 6480464 Cyclosporine results in decreased expression of CYP17A1 mRNA CTD PMID:19770486 cyclosporin A decreases expression ISO RGD:1350540 6480464 Cyclosporine results in decreased expression of CYP17A1 mRNA CTD PMID:25562108 cypermethrin decreases expression ISO RGD:737222 6480464 cypermethrin results in decreased expression of CYP17A1 mRNA, cypermethrin results in decreased expression of CYP17A1 protein CTD PMID:21397294 more ... DDT multiple interactions ISO RGD:737222 6480464 fulvestrant inhibits the reaction [DDT results in increased expression of CYP17A1 mRNA] CTD PMID:23684557 DDT increases expression ISO RGD:737222 6480464 DDT results in increased expression of CYP17A1 mRNA CTD PMID:23684557 decabromodiphenyl ether decreases activity EXP 6480464 decabromobiphenyl ether results in decreased activity of CYP17A1 protein CTD PMID:18495385 dehydroepiandrosterone affects chemical synthesis ISO RGD:1350540 6480464 CYP17A1 protein affects the chemical synthesis of Dehydroepiandrosterone CTD PMID:15562394 , PMID:16030167 dehydroepiandrosterone multiple interactions ISO RGD:1350540 6480464 [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone more ... CTD PMID:29100959 dehydroepiandrosterone affects metabolic processing EXP 6480464 CYP17A1 protein affects the metabolism of Dehydroepiandrosterone CTD PMID:15261307 dehydroepiandrosterone affects chemical synthesis ISO RGD:737222 6480464 CYP17A1 protein affects the chemical synthesis of Dehydroepiandrosterone CTD PMID:15666818 dehydroepiandrosterone affects chemical synthesis EXP 6480464 CYP17A1 protein affects the chemical synthesis of Dehydroepiandrosterone CTD PMID:15934942 dehydroepiandrosterone decreases expression ISO RGD:1350540 6480464 Dehydroepiandrosterone results in decreased expression of CYP17A1 mRNA CTD PMID:15625562 deoxynivalenol increases expression ISO RGD:1350540 6480464 deoxynivalenol results in increased expression of CYP17A1 mRNA CTD PMID:22982764 desogestrel multiple interactions ISO RGD:1350540 6480464 [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP17A1 mRNA CTD PMID:18160741 dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with Dibutyl Phthalate] results in decreased expression of CYP17A1 mRNA CTD PMID:22615892 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of CYP17A1 mRNA CTD PMID:29902490 dexamethasone multiple interactions ISO RGD:737222 6480464 Berberine inhibits the reaction [Dexamethasone results in increased expression of CYP17A1 mRNA] CTD PMID:20462044 dexamethasone increases expression ISO RGD:737222 6480464 Dexamethasone results in increased expression of CYP17A1 mRNA CTD PMID:20462044 Di-n-hexyl phthalate decreases expression EXP 6480464 di-n-hexyl phthalate results in decreased expression of CYP17A1 mRNA, di-n-hexyl phthalate results in decreased expression of CYP17A1 protein CTD PMID:22112501 more ... diarsenic trioxide decreases expression ISO RGD:737222 6480464 Arsenic Trioxide results in decreased expression of CYP17A1 mRNA CTD PMID:18630931 dibromoacetic acid decreases expression EXP 6480464 dibromoacetic acid results in decreased expression of CYP17A1 mRNA CTD PMID:21046364 dibutyl phthalate multiple interactions EXP 6480464 [Dexamethasone co-treated with Dibutyl Phthalate] results in decreased expression of CYP17A1 mRNA more ... CTD PMID:17884934 more ... dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of CYP17A1 mRNA, Dibutyl Phthalate results in decreased expression of CYP17A1 protein CTD PMID:14617579 more ... dibutyl phthalate multiple interactions ISO RGD:737222 6480464 [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA CTD PMID:29029336 dibutyl phthalate increases expression ISO RGD:737222 6480464 Dibutyl Phthalate results in increased expression of CYP17A1 mRNA CTD PMID:25765776 dibutyl phthalate decreases expression ISO RGD:737222 6480464 Dibutyl Phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:22511013 diclofenac increases expression ISO RGD:737222 6480464 Diclofenac results in increased expression of CYP17A1 mRNA CTD PMID:26934552 Dicyclohexyl phthalate decreases expression EXP 6480464 dicyclohexyl phthalate results in decreased expression of CYP17A1 mRNA, dicyclohexyl phthalate results in decreased expression of CYP17A1 protein CTD PMID:30391266 diethyl phthalate multiple interactions EXP 6480464 diethyl phthalate inhibits the reaction [NR5A1 binds to CYP17A1 promoter] CTD PMID:17884934 diethyl phthalate decreases expression EXP 6480464 diethyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:29325824 diethylstilbestrol affects expression ISO RGD:737222 6480464 Diethylstilbestrol affects the expression of CYP17A1 mRNA, Diethylstilbestrol affects the expression of CYP17A1 protein CTD PMID:15196701 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of CYP17A1 mRNA, Diethylstilbestrol results in decreased expression of CYP17A1 protein CTD PMID:22615892 , PMID:9361775 diheptyl phthalate decreases expression EXP 6480464 diheptyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:22112501 diisobutyl phthalate decreases expression EXP 6480464 diisobutyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:22112501 , PMID:28655647 diisononyl phthalate decreases expression EXP 6480464 diisononyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:22112501 , PMID:25445723 dipentyl phthalate multiple interactions EXP 6480464 [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA CTD PMID:25055962 dipentyl phthalate decreases expression EXP 6480464 di-n-pentyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:22112501 more ... dipentyl phthalate decreases activity EXP 6480464 di-n-pentyl phthalate results in decreased activity of CYP17A1 protein CTD PMID:6829050 disulfiram multiple interactions ISO RGD:737222 6480464 Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 drospirenone multiple interactions ISO RGD:1350540 6480464 [Ethinyl Estradiol co-treated with drospirenone] results in decreased activity of CYP17A1 protein CTD PMID:17418832 enniatin decreases expression ISO RGD:1350540 6480464 enniatins results in decreased expression of CYP17A1 mRNA CTD PMID:25625232 enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP17A1 mRNA CTD PMID:25607892 equol decreases expression ISO RGD:737222 6480464 Equol results in decreased expression of CYP17A1 mRNA CTD PMID:26876617 estrone affects abundance ISO RGD:1350540 6480464 CYP17A1 protein affects the abundance of Estrone CTD PMID:21427057 farnesyl diphosphate multiple interactions EXP 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA] CTD PMID:21918126 fenarimol increases expression ISO RGD:737222 6480464 fenarimol results in increased expression of CYP17A1 mRNA, fenarimol results in increased expression of CYP17A1 protein CTD PMID:21722721 fenvalerate decreases expression ISO RGD:737222 6480464 fenvalerate results in decreased expression of CYP17A1 mRNA, fenvalerate results in decreased expression of CYP17A1 protein CTD PMID:20063364 , PMID:20138952 flurbiprofen decreases activity ISO RGD:1350540 6480464 Flurbiprofen results in decreased activity of CYP17A1 protein CTD PMID:31184881 flurbiprofen decreases activity EXP 6480464 Flurbiprofen results in decreased activity of CYP17A1 protein CTD PMID:31184881 flutamide increases expression ISO RGD:737222 6480464 Flutamide results in increased expression of CYP17A1 mRNA CTD PMID:11509743 flutamide increases expression EXP 6480464 Flutamide results in increased expression of CYP17A1 mRNA CTD PMID:14967917 more ... flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of CYP17A1 mRNA CTD PMID:24136188 fulvestrant increases expression ISO RGD:737222 6480464 fulvestrant results in increased expression of CYP17A1 mRNA CTD PMID:17158782 fulvestrant multiple interactions ISO RGD:737222 6480464 fulvestrant inhibits the reaction [DDT results in increased expression of CYP17A1 mRNA] CTD PMID:23684557 fumonisin B1 decreases expression ISO RGD:737222 6480464 fumonisin B1 results in decreased expression of CYP17A1 mRNA CTD PMID:16221962 galaxolide decreases activity ISO RGD:1350540 6480464 galaxolide results in decreased activity of CYP17A1 protein CTD PMID:23084589 galaxolide increases activity ISO RGD:1350540 6480464 galaxolide results in increased activity of CYP17A1 protein CTD PMID:23084589 galaxolide multiple interactions ISO RGD:1350540 6480464 [galaxolide co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein, [galaxolide co-treated with Cyclic AMP] results in increased activity of CYP17A1 protein CTD PMID:23084589 gamma-hexachlorocyclohexane multiple interactions ISO RGD:1350540 6480464 Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] CTD PMID:17080404 geldanamycin increases expression ISO RGD:737222 6480464 geldanamycin results in increased expression of CYP17A1 mRNA CTD PMID:15711029 genistein decreases expression EXP 6480464 Genistein results in decreased expression of CYP17A1 mRNA CTD PMID:15901920 genistein decreases expression ISO RGD:737222 6480464 Genistein results in decreased expression of CYP17A1 mRNA CTD PMID:21624456 , PMID:26792615 genistein increases expression ISO RGD:737222 6480464 Genistein results in increased expression of CYP17A1 mRNA CTD PMID:18281260 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of CYP17A1 mRNA CTD PMID:22061828 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of CYP17A1 mRNA CTD PMID:24136188 herbicide increases expression EXP 6480464 Herbicides results in increased expression of CYP17A1 mRNA CTD PMID:30268827 hexane affects expression EXP 6480464 n-hexane affects the expression of CYP17A1 mRNA, n-hexane affects the expression of CYP17A1 protein CTD PMID:26410608 hexane affects methylation EXP 6480464 n-hexane affects the methylation of CYP17A1 promoter CTD PMID:26410608 HT-2 Toxin decreases expression ISO RGD:1350540 6480464 HT-2 toxin results in decreased expression of CYP17A1 mRNA CTD PMID:22982764 hydrazine increases expression EXP 6480464 hydrazine results in increased expression of CYP17A1 mRNA CTD PMID:15370871 imidacloprid decreases expression EXP 6480464 imidacloprid results in decreased expression of CYP17A1 mRNA CTD PMID:27782041 isoflavones increases activity EXP 6480464 Isoflavones results in increased activity of CYP17A1 protein CTD PMID:15698548 isoliquiritigenin decreases expression ISO RGD:737222 6480464 isoliquiritigenin results in decreased expression of CYP17A1 mRNA CTD PMID:27773742 ketoconazole multiple interactions ISO RGD:1350540 6480464 Ketoconazole inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] CTD PMID:16935330 ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of CYP17A1 protein CTD PMID:15934942 , PMID:25993309 ketoconazole decreases activity ISO RGD:1350540 6480464 Ketoconazole results in decreased activity of CYP17A1 protein CTD PMID:11118046 more ... ketoconazole decreases expression ISO RGD:1350540 6480464 Ketoconazole results in decreased expression of CYP17A1 mRNA CTD PMID:16935330 lamotrigine decreases activity ISO RGD:1350540 6480464 lamotrigine results in decreased activity of CYP17A1 protein CTD PMID:15730543 lead diacetate increases expression ISO RGD:737222 6480464 lead acetate results in increased expression of CYP17A1 mRNA CTD PMID:21335049 lead diacetate decreases expression ISO RGD:737222 6480464 lead acetate results in decreased expression of CYP17A1 mRNA, lead acetate results in decreased expression of CYP17A1 protein CTD PMID:22806249 leflunomide decreases expression EXP 6480464 leflunomide results in decreased expression of CYP17A1 mRNA CTD PMID:24136188 levetiracetam decreases expression ISO RGD:1350540 6480464 Levetiracetam results in decreased expression of CYP17A1 mRNA CTD PMID:19566492 levonorgestrel multiple interactions ISO RGD:1350540 6480464 [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CYP17A1 mRNA CTD PMID:19074003 linuron decreases expression EXP 6480464 Linuron results in decreased expression of CYP17A1 mRNA CTD PMID:28007637 , PMID:28705778 lipopolysaccharide decreases expression ISO RGD:737222 6480464 Lipopolysaccharides results in decreased expression of CYP17A1 mRNA, Lipopolysaccharides results in decreased expression of CYP17A1 protein CTD PMID:8828518 lipopolysaccharide increases expression ISO RGD:737222 6480464 Lipopolysaccharides results in increased expression of CYP17A1 mRNA CTD PMID:27339419 lipopolysaccharide multiple interactions ISO RGD:737222 6480464 [Lipopolysaccharides results in decreased expression of CYP17A1 protein] which results in decreased abundance of Testosterone CTD PMID:8828518 metformin decreases expression ISO RGD:737222 6480464 Metformin results in decreased expression of CYP17A1 mRNA CTD PMID:23166782 methotrexate affects expression ISO RGD:737222 6480464 Methotrexate affects the expression of CYP17A1 mRNA CTD PMID:18502557 methoxyacetic acid increases expression ISO RGD:737222 6480464 methoxyacetic acid results in increased expression of CYP17A1 mRNA CTD PMID:18486176 methoxychlor multiple interactions ISO RGD:737222 6480464 [Estradiol co-treated with Methoxychlor metabolite] results in decreased expression of CYP17A1 mRNA CTD PMID:11509743 methoxychlor decreases expression ISO RGD:737222 6480464 Methoxychlor metabolite results in decreased expression of CYP17A1 mRNA, Methoxychlor results in decreased expression of CYP17A1 mRNA CTD PMID:11509743 , PMID:21514315 metyrapone multiple interactions ISO RGD:1350540 6480464 Metyrapone inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] CTD PMID:16935330 Mitotane decreases expression ISO RGD:1350540 6480464 Mitotane results in decreased expression of CYP17A1 mRNA CTD PMID:23254310 Mitotane multiple interactions ISO RGD:1350540 6480464 Mitotane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA] CTD PMID:22546480 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of CYP17A1 mRNA CTD PMID:16809437 mono(2-ethylhexyl) phthalate decreases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of CYP17A1 mRNA, mono-(2-ethylhexyl)phthalate results in decreased expression of CYP17A1 protein CTD PMID:16809437 , PMID:22087261 mono(2-ethylhexyl) phthalate affects expression EXP 6480464 mono-(2-ethylhexyl)phthalate affects the expression of CYP17A1 CTD PMID:19560483 Monobutylphthalate decreases expression EXP 6480464 monobutyl phthalate results in decreased expression of CYP17A1 mRNA CTD PMID:22511013 mycotoxin increases expression ISO RGD:1350540 6480464 Mycotoxins results in increased expression of CYP17A1 mRNA CTD PMID:23665424 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA], Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] CTD PMID:29567110 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:737222 6480464 Ethylnitrosourea results in increased mutagenesis of CYP17A1 mRNA CTD PMID:27776689 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP17A1 mRNA, [nodularin co-treated with Diethylnitrosamine] results in decreased activity of CYP17A1 protein CTD PMID:12112309 , PMID:17602206 N-nitrosodiethylamine increases expression ISO RGD:737222 6480464 Diethylnitrosamine results in increased expression of CYP17A1 mRNA CTD PMID:24535843 N-nitrosodiethylamine decreases activity EXP 6480464 Diethylnitrosamine results in decreased activity of CYP17A1 protein CTD PMID:12112309 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of CYP17A1 mRNA CTD PMID:17072980 nickel sulfate multiple interactions EXP 6480464 [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 mRNA more ... CTD PMID:29567110 nickel sulfate decreases expression EXP 6480464 nickel sulfate results in decreased expression of CYP17A1 mRNA, nickel sulfate results in decreased expression of CYP17A1 protein CTD PMID:29567110 nicotine decreases expression ISO RGD:1350540 6480464 Nicotine results in decreased expression of CYP17A1 mRNA CTD PMID:24709674 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of CYP17A1 mRNA, Nicotine results in decreased expression of CYP17A1 protein CTD PMID:27782041 , PMID:28986172 Nodularin multiple interactions EXP 6480464 [nodularin co-treated with Diethylnitrosamine] results in decreased activity of CYP17A1 protein CTD PMID:12112309 oxycodone affects expression EXP 6480464 Oxycodone affects the expression of CYP17A1 mRNA CTD PMID:20487198 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of CYP17A1 mRNA CTD PMID:23439660 ozone decreases expression ISO RGD:737222 6480464 Ozone results in decreased expression of CYP17A1 mRNA CTD PMID:16183385 p-tert-Amylphenol multiple interactions ISO RGD:737222 6480464 [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA CTD PMID:29029336 p-tert-Amylphenol decreases expression ISO RGD:737222 6480464 4-tert-octylphenol results in decreased expression of CYP17A1 mRNA CTD PMID:17696135 paracetamol multiple interactions ISO RGD:737222 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CYP17A1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP17A1 mRNA] CTD PMID:17585979 paracetamol multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP17A1 mRNA CTD PMID:25607892 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CYP17A1 mRNA CTD PMID:17202762 , PMID:30723492 paracetamol affects expression ISO RGD:737222 6480464 Acetaminophen affects the expression of CYP17A1 mRNA CTD PMID:17562736 pentachlorophenol decreases expression ISO RGD:1350540 6480464 Pentachlorophenol results in decreased expression of CYP17A1 mRNA CTD PMID:21296122 pentachlorophenol increases expression ISO RGD:737222 6480464 Pentachlorophenol results in increased expression of CYP17A1 mRNA CTD PMID:23892564 perflubron increases expression ISO RGD:1350540 6480464 perflubron results in increased expression of CYP17A1 mRNA CTD PMID:25871633 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of CYP17A1 mRNA, perfluorododecanoic acid results in decreased expression of CYP17A1 protein CTD PMID:17400581 , PMID:30489073 perfluorononanoic acid increases expression ISO RGD:737222 6480464 perfluorononanoic acid results in increased expression of CYP17A1 mRNA CTD PMID:25543169 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CYP17A1 mRNA CTD PMID:16221955 more ... perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1350540 6480464 perfluorooctane sulfonic acid results in decreased expression of CYP17A1 mRNA CTD PMID:23074026 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CYP17A1 mRNA CTD PMID:16221955 more ... perfluorooctanoic acid decreases expression ISO RGD:737222 6480464 perfluorooctanoic acid results in decreased expression of CYP17A1 mRNA, perfluorooctanoic acid results in decreased expression of CYP17A1 protein CTD PMID:20118188 more ... perfluorooctanoic acid increases expression ISO RGD:737222 6480464 perfluorooctanoic acid results in increased expression of CYP17A1 mRNA CTD PMID:17681415 perfluorooctanoic acid multiple interactions ISO RGD:737222 6480464 [perfluorooctanoic acid co-treated with PPARA] results in increased expression of CYP17A1 mRNA more ... CTD PMID:20118188 more ... phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CYP17A1 mRNA CTD PMID:19162173 phenobarbital increases expression ISO RGD:737222 6480464 Phenobarbital results in increased expression of CYP17A1 mRNA CTD PMID:19270015 , PMID:23091169 pioglitazone multiple interactions ISO RGD:1350540 6480464 pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased activity of CYP17A1 protein], pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of CYP17A1 mRNA] CTD PMID:17138841 pioglitazone decreases expression ISO RGD:1350540 6480464 pioglitazone results in decreased expression of CYP17A1 mRNA CTD PMID:17138841 pioglitazone decreases activity ISO RGD:1350540 6480464 pioglitazone results in decreased activity of CYP17A1 protein CTD PMID:15072549 , PMID:17138841 piperonyl butoxide decreases expression EXP 6480464 Piperonyl Butoxide results in decreased expression of CYP17A1 mRNA CTD PMID:22484513 pirinixic acid multiple interactions ISO RGD:737222 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of CYP17A1 mRNA] CTD PMID:20059764 pirinixic acid multiple interactions EXP 6480464 pirinixic acid promotes the reaction [PPARA protein binds to CYP17A1 promoter] CTD PMID:23358192 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of CYP17A1 mRNA CTD PMID:19162173 more ... pirinixic acid increases expression ISO RGD:737222 6480464 pirinixic acid results in increased expression of CYP17A1 mRNA CTD PMID:18301758 , PMID:20059764 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of CYP17A1 protein CTD PMID:30315952 pregnenolone affects metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein affects the metabolism of Pregnenolone CTD PMID:16030167 , PMID:16054388 pregnenolone multiple interactions ISO RGD:1350540 6480464 [[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone more ... CTD PMID:17194026 , PMID:29100959 pregnenolone increases hydroxylation ISO RGD:1350540 6480464 CYP17A1 protein mutant form results in increased hydroxylation of Pregnenolone, CYP17A1 protein results in increased hydroxylation of Pregnenolone CTD PMID:15562394 more ... pregnenolone multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Pregnenolone binds to CYP17A1 protein] CTD PMID:15666820 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of CYP17A1 mRNA CTD PMID:19162173 prochloraz decreases activity ISO RGD:1350540 6480464 prochloraz results in decreased activity of CYP17A1 protein CTD PMID:19733639 prochloraz decreases expression ISO RGD:1350540 6480464 prochloraz results in decreased expression of CYP17A1 mRNA CTD PMID:19733639 , PMID:25324206 prochloraz multiple interactions ISO RGD:1350540 6480464 prochloraz results in decreased expression of and results in decreased activity of CYP17A1 protein CTD PMID:25324206 prochloraz increases expression EXP 6480464 prochloraz results in increased expression of CYP17A1 mRNA, prochloraz results in increased expression of CYP17A1 protein CTD PMID:16375936 prochloraz multiple interactions EXP 6480464 [prochloraz results in decreased activity of CYP17A1 protein] which results in decreased chemical synthesis of Testosterone CTD PMID:17234647 , PMID:17369198 prochloraz decreases activity EXP 6480464 prochloraz results in decreased activity of CYP17A1 protein CTD PMID:16375936 more ... profenofos increases expression EXP 6480464 profenofos results in increased expression of CYP17A1 mRNA CTD PMID:17569032 progesterone multiple interactions ISO RGD:1350540 6480464 [[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone more ... CTD PMID:14522586 more ... progesterone multiple interactions EXP 6480464 [[3 more ... CTD PMID:19603415 progesterone increases hydroxylation ISO RGD:1350540 6480464 CYP17A1 protein results in increased hydroxylation of Progesterone CTD PMID:15562394 more ... progesterone affects metabolic processing ISO RGD:1350540 6480464 CYP17A1 protein affects the metabolism of Progesterone CTD PMID:16030167 , PMID:16054388 progesterone affects metabolic processing EXP 6480464 CYP17A1 protein affects the metabolism of Progesterone CTD PMID:15261307 prostaglandin E2 increases expression ISO RGD:1350540 6480464 Dinoprostone results in increased expression of CYP17A1 mRNA CTD PMID:19001523 pyruvic acid multiple interactions ISO RGD:1350540 6480464 Pyruvic Acid promotes the reaction [CTBP1 protein binds to CYP17A1 promoter] more ... CTD PMID:18184656 pyruvic acid increases expression ISO RGD:1350540 6480464 Pyruvic Acid results in increased expression of CYP17A1 mRNA CTD PMID:18184656 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA], Quercetin inhibits the reaction [Atrazine results in increased expression of CYP17A1 mRNA] CTD PMID:23200735 resveratrol multiple interactions EXP 6480464 [[resveratrol analog co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone more ... CTD PMID:19603415 , PMID:24524197 resveratrol decreases expression ISO RGD:1350540 6480464 resveratrol analog results in decreased expression of CYP17A1 mRNA, resveratrol results in decreased expression of CYP17A1 mRNA CTD PMID:24610083 , PMID:24875446 resveratrol decreases activity ISO RGD:1350540 6480464 resveratrol analog results in decreased activity of CYP17A1 protein, resveratrol results in decreased activity of CYP17A1 protein CTD PMID:24610083 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of CYP17A1 mRNA CTD PMID:22719052 , PMID:24524197 rotenone increases expression EXP 6480464 Rotenone results in increased expression of CYP17A1 mRNA CTD PMID:28374803 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA], SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] CTD PMID:29567110 sertraline decreases expression EXP 6480464 Sertraline results in decreased expression of CYP17A1 mRNA CTD PMID:29850907 simvastatin multiple interactions EXP 6480464 [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA more ... CTD PMID:21918126 more ... simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of CYP17A1 mRNA CTD PMID:21918126 , PMID:24524197 sodium arsenite decreases expression ISO RGD:737222 6480464 sodium arsenite results in decreased expression of CYP17A1 mRNA, sodium arsenite results in decreased expression of CYP17A1 protein CTD PMID:28414027 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CYP17A1 mRNA, sodium arsenite results in decreased expression of CYP17A1 protein CTD PMID:30557709 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of CYP17A1 mRNA CTD PMID:25993096 sphingosine increases expression ISO RGD:1350540 6480464 Sphingosine results in increased expression of CYP17A1 mRNA CTD PMID:15666826 sphingosine 1-phosphate increases expression ISO RGD:1350540 6480464 sphingosine 1-phosphate results in increased expression of CYP17A1 mRNA CTD PMID:15666826 T-2 Toxin multiple interactions ISO RGD:737222 6480464 [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein CTD PMID:25962641 tamoxifen decreases expression ISO RGD:737222 6480464 Tamoxifen results in decreased expression of CYP17A1 mRNA CTD PMID:25123088 tamoxifen multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in increased expression of CYP17A1 mRNA CTD PMID:17630414 tamoxifen affects expression ISO RGD:737222 6480464 Tamoxifen affects the expression of CYP17A1 mRNA CTD PMID:20937368 tamoxifen increases response to substance ISO RGD:1350540 6480464 CYP17A1 gene polymorphism results in increased susceptibility to Tamoxifen CTD PMID:15706422 terbutylazine decreases expression ISO RGD:737222 6480464 terbutylazine results in decreased expression of CYP17A1 mRNA CTD PMID:23591565 Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of CYP17A1 mRNA CTD PMID:21515302 testosterone affects abundance ISO RGD:1350540 6480464 CYP17A1 protein affects the abundance of Testosterone CTD PMID:21427057 testosterone multiple interactions EXP 6480464 [bisphenol A results in decreased expression of CYP17A1 protein] which results in decreased abundance of Testosterone more ... CTD PMID:14605012 more ... testosterone decreases expression ISO RGD:737222 6480464 Testosterone results in decreased expression of CYP17A1 mRNA CTD PMID:20600201 , PMID:21669218 testosterone affects chemical synthesis ISO RGD:737222 6480464 CYP17A1 protein affects the chemical synthesis of Testosterone CTD PMID:15932923 testosterone multiple interactions ISO RGD:737222 6480464 [[titanium dioxide results in decreased expression of CYP17A1 mRNA] co-treated with [titanium dioxide results in decreased expression of HSD17B10 mRNA]] results in increased chemical synthesis of Testosterone more ... CTD PMID:14630719 more ... testosterone decreases expression ISO RGD:1350540 6480464 Testosterone results in decreased expression of CYP17A1 mRNA CTD PMID:15625562 testosterone enanthate multiple interactions ISO RGD:1350540 6480464 [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP17A1 mRNA, [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CYP17A1 mRNA CTD PMID:18160741 testosterone enanthate decreases expression EXP 6480464 testosterone enanthate results in decreased expression of CYP17A1 mRNA CTD PMID:21427060 , PMID:25603467 Testosterone propionate decreases expression ISO RGD:737222 6480464 Testosterone Propionate results in decreased expression of CYP17A1 mRNA CTD PMID:15601916 testosterone undecanoate decreases expression ISO RGD:1350540 6480464 testosterone undecanoate results in decreased expression of CYP17A1 mRNA CTD PMID:19074003 testosterone undecanoate multiple interactions ISO RGD:1350540 6480464 [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CYP17A1 mRNA CTD PMID:19074003 tetrachloroethene increases expression ISO RGD:737222 6480464 Tetrachloroethylene results in increased expression of CYP17A1 mRNA CTD PMID:28973375 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CYP17A1 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP17A1 mRNA] CTD PMID:31150632 tetracycline decreases expression ISO RGD:737222 6480464 Tetracycline results in decreased expression of CYP17A1 mRNA CTD PMID:16917069 tetraphene increases expression EXP 6480464 benz(a)anthracene results in increased expression of CYP17A1 mRNA CTD PMID:23358148 tetraphene multiple interactions ISO RGD:737222 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CYP17A1 mRNA CTD PMID:27858113 tetraphene decreases expression ISO RGD:737222 6480464 benz(a)anthracene results in decreased expression of CYP17A1 mRNA CTD PMID:26377693 titanium dioxide increases expression ISO RGD:737222 6480464 titanium dioxide results in increased expression of CYP17A1 mRNA CTD PMID:23131501 titanium dioxide multiple interactions ISO RGD:737222 6480464 [[titanium dioxide results in decreased expression of CYP17A1 mRNA] co-treated with [titanium dioxide results in decreased expression of HSD17B10 mRNA]] results in increased chemical synthesis of Testosterone CTD PMID:24241477 titanium dioxide decreases expression ISO RGD:737222 6480464 titanium dioxide results in decreased expression of CYP17A1 mRNA, titanium dioxide results in decreased expression of CYP17A1 protein CTD PMID:24241477 topiramate decreases activity ISO RGD:1350540 6480464 topiramate results in decreased activity of CYP17A1 protein CTD PMID:15730543 torcetrapib increases expression ISO RGD:1350540 6480464 torcetrapib results in increased expression of CYP17A1 mRNA CTD PMID:28235592 tramadol decreases activity ISO RGD:1350540 6480464 Tramadol results in decreased activity of CYP17A1 protein CTD PMID:29100959 trans-cinnamic acid decreases activity ISO RGD:1350540 6480464 cinnamic acid analog results in decreased activity of CYP17A1 protein CTD PMID:15072549 triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of CYP17A1 mRNA CTD PMID:19118620 triphenyl phosphate decreases expression ISO RGD:737222 6480464 triphenyl phosphate results in decreased expression of CYP17A1 mRNA CTD PMID:26049154 , PMID:26183808 triphenyl phosphate multiple interactions ISO RGD:1350540 6480464 triphenyl phosphate inhibits the reaction [CGB3 protein results in increased expression of CYP17A1 mRNA] CTD PMID:26049154 triphenylstannane multiple interactions EXP 6480464 [triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of CYP17A1 mRNA CTD PMID:30772500 tris(2-butoxyethyl) phosphate decreases expression ISO RGD:1350540 6480464 tris(2-butoxyethyl) phosphate results in decreased expression of CYP17A1 mRNA CTD PMID:29024780 tris(2-chloroethyl) phosphate multiple interactions ISO RGD:1350540 6480464 tris(chloroethyl)phosphate inhibits the reaction [CGB3 protein results in increased expression of CYP17A1 mRNA] CTD PMID:26049154 tris(2-chloroethyl) phosphate decreases expression ISO RGD:737222 6480464 tris(chloroethyl)phosphate results in decreased expression of CYP17A1 mRNA CTD PMID:26049154 , PMID:26183808 troglitazone decreases activity ISO RGD:1350540 6480464 troglitazone results in decreased activity of CYP17A1 protein CTD PMID:15072549 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of CYP17A1 mRNA CTD PMID:21515302 uranium atom decreases expression EXP 6480464 Uranium analog results in decreased expression of CYP17A1 mRNA CTD PMID:27544493 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of CYP17A1 mRNA CTD PMID:24136188 valproic acid decreases expression ISO RGD:1350540 6480464 Valproic Acid results in decreased expression of CYP17A1 mRNA CTD PMID:19566492 valproic acid multiple interactions ISO RGD:1350540 6480464 Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] CTD PMID:20726872 valproic acid increases expression ISO RGD:1350540 6480464 Valproic Acid results in increased expression of CYP17A1 mRNA, Valproic Acid results in increased expression of CYP17A1 protein CTD PMID:14576182 valproic acid affects expression ISO RGD:737222 6480464 Valproic Acid affects the expression of CYP17A1 mRNA CTD PMID:17292431 venlafaxine hydrochloride multiple interactions ISO RGD:1350540 6480464 Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone] more ... CTD PMID:29100959 venlafaxine hydrochloride decreases activity ISO RGD:1350540 6480464 Venlafaxine Hydrochloride results in decreased activity of CYP17A1 protein CTD PMID:29100959 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of CYP17A1 mRNA CTD PMID:14967917 , PMID:23160963 zearalenone decreases expression ISO RGD:737222 6480464 Zearalenone results in decreased expression of CYP17A1 mRNA CTD PMID:24512812 ziram decreases expression EXP 6480464 Ziram results in decreased expression of CYP17A1 mRNA, Ziram results in decreased expression of CYP17A1 protein CTD PMID:28973382 , PMID:30422632 ziram decreases activity EXP 6480464 Ziram results in decreased activity of CYP17A1 protein CTD PMID:28973382 ziram affects expression EXP 6480464 Ziram affects the expression of CYP17A1 mRNA, Ziram affects the expression of CYP17A1 protein CTD PMID:29627606
Gene-Chemical Interaction Annotations
