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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2456
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Acc ID: CHEBI:39185
Term: thiamethoxam
Definition: An oxadiazane that is tetrahydro-N-nitro-4H-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively.
Chemical ID: MESH:C416660
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp17a1decreases expressionEXP 6480464CTDThiamethoxam results in decreased expression of CYP17A1 mRNAPMID:34181816
Cyp17a1multiple interactionsEXP 6480464CTDPlant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP17A1 mRNA]PMID:34181816
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