GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp17a1 | decreases activity | EXP | | 6480464 | CTD | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased activity of CYP17A1 protein | PMID:24451217 | Cyp17a1 | decreases activity | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased activity of CYP17A1 protein | PMID:24451217 | Cyp17a1 | decreases expression | ISO | Cyp17a1 (Mus musculus) | 6480464 | CTD | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased expression of CYP17A1 mRNA | PMID:11509743 | Cyp17a1 | multiple interactions | ISO | Cyp17a1 (Mus musculus) | 6480464 | CTD | [Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in decreased expression of CYP17A1 mRNA | PMID:11509743 | |
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