(+)-taxifolin increases expression ISO RGD:1353234 6480464 taxifolin results in increased expression of XRCC4 mRNA CTD PMID:17541156 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1353234 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of XRCC4 mRNA, epigallocatechin gallate inhibits the reaction [potassium chromate(VI) results in decreased expression of XRCC4 mRNA] CTD PMID:22079256 (1->4)-beta-D-glucan multiple interactions ISO RGD:1550337 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of XRCC4 mRNA CTD PMID:36331819 1,2-dimethylhydrazine multiple interactions ISO RGD:1550337 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of XRCC4 mRNA] CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO RGD:1550337 6480464 1, 2-Dimethylhydrazine results in decreased expression of XRCC4 mRNA CTD PMID:22206623 1H-pyrazole increases expression ISO RGD:1550337 6480464 pyrazole results in increased expression of XRCC4 mRNA CTD PMID:17945193 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1550337 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to XRCC4 promoter] CTD PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of XRCC4 mRNA CTD PMID:33387578 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of XRCC4 mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression ISO RGD:1353234 6480464 Lactic Acid results in decreased expression of XRCC4 mRNA CTD PMID:30851411 3-chlorophenol increases expression ISO RGD:1353234 6480464 3-chlorophenol results in increased expression of XRCC4 mRNA CTD PMID:18486366 aflatoxin B1 affects expression ISO RGD:1353234 6480464 Aflatoxin B1 affects the expression of XRCC4 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:1550337 6480464 Aflatoxin B1 results in decreased expression of XRCC4 mRNA CTD PMID:19770486 aflatoxin M1 decreases expression ISO RGD:1353234 6480464 Aflatoxin M1 results in decreased expression of XRCC4 mRNA CTD PMID:30928695 aphidicolin decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Aphidicolin CTD PMID:21785230 aristolochic acid A decreases expression ISO RGD:1353234 6480464 aristolochic acid I results in decreased expression of XRCC4 mRNA CTD PMID:33212167 arsane decreases expression ISO RGD:1353234 6480464 Arsenic results in decreased expression of XRCC4 mRNA, Arsenic results in decreased expression of XRCC4 protein CTD PMID:21332098 arsane multiple interactions ISO RGD:1353234 6480464 Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 mRNA], Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 protein] CTD PMID:21332098 arsenic atom decreases expression ISO RGD:1353234 6480464 Arsenic results in decreased expression of XRCC4 mRNA, Arsenic results in decreased expression of XRCC4 protein CTD PMID:21332098 arsenic atom multiple interactions ISO RGD:1353234 6480464 Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 mRNA], Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 protein] CTD PMID:21332098 arsenous acid decreases expression ISO RGD:1353234 6480464 Arsenic Trioxide results in decreased expression of XRCC4 mRNA CTD PMID:17530438 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of XRCC4 gene CTD PMID:35440735 benzene decreases expression ISO RGD:1550337 6480464 Benzene results in decreased expression of XRCC4 mRNA, Benzene results in decreased expression of XRCC4 protein CTD PMID:35963423 benzo[a]pyrene decreases expression ISO RGD:1353234 6480464 Benzo(a)pyrene results in decreased expression of XRCC4 mRNA CTD PMID:20064835 more ... benzo[a]pyrene increases expression ISO RGD:1550337 6480464 Benzo(a)pyrene results in increased expression of XRCC4 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:1550337 6480464 Benzo(a)pyrene results in decreased expression of XRCC4 mRNA CTD PMID:19770486 , PMID:21715664 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1353234 6480464 7 more ... CTD PMID:19150397 more ... bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of XRCC4 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of XRCC4 mRNA CTD PMID:30816183 more ... cadmium atom multiple interactions ISO RGD:1353234 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of XRCC4 mRNA CTD PMID:31738976 cadmium dichloride multiple interactions ISO RGD:1353234 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of XRCC4 mRNA CTD PMID:31738976 caffeine affects phosphorylation ISO RGD:1353234 6480464 Caffeine affects the phosphorylation of XRCC4 protein CTD PMID:35688186 camptothecin decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Camptothecin CTD PMID:21785230 camptothecin increases methylation ISO RGD:1353234 6480464 Camptothecin results in increased methylation of XRCC4 gene CTD PMID:30720231 chlorpromazine decreases expression ISO RGD:1353234 6480464 Chlorpromazine results in decreased expression of XRCC4 mRNA CTD PMID:15924885 chromium(6+) decreases expression ISO RGD:1353234 6480464 chromium hexavalent ion results in decreased expression of XRCC4 mRNA CTD PMID:27793765 cisplatin decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Cisplatin CTD PMID:21785230 cisplatin decreases expression ISO RGD:1550337 6480464 Cisplatin results in decreased expression of XRCC4 mRNA CTD PMID:21151649 coumarin decreases phosphorylation ISO RGD:1353234 6480464 coumarin results in decreased phosphorylation of XRCC4 protein CTD PMID:35688186 curcumin multiple interactions ISO RGD:1353234 6480464 Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 mRNA], Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 protein] CTD PMID:21332098 diarsenic trioxide decreases expression ISO RGD:1353234 6480464 Arsenic Trioxide results in decreased expression of XRCC4 mRNA CTD PMID:17530438 doxorubicin increases expression ISO RGD:1353234 6480464 Doxorubicin results in increased expression of XRCC4 mRNA CTD PMID:30031762 entinostat increases expression ISO RGD:1353234 6480464 entinostat results in increased expression of XRCC4 mRNA CTD PMID:27188386 etoposide multiple interactions ISO RGD:1353234 6480464 BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein] CTD PMID:16417649 etoposide decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Etoposide CTD PMID:21785230 etoposide increases expression ISO RGD:1353234 6480464 Etoposide results in increased expression of XRCC4 protein CTD PMID:16417649 floxuridine decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Floxuridine CTD PMID:21785230 folic acid decreases expression ISO RGD:1550337 6480464 Folic Acid results in decreased expression of XRCC4 mRNA CTD PMID:25629700 folic acid multiple interactions ISO RGD:1550337 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of XRCC4 mRNA] CTD PMID:22206623 formaldehyde decreases expression ISO RGD:1353234 6480464 Formaldehyde results in decreased expression of XRCC4 mRNA CTD PMID:23649840 gallic acid decreases expression ISO RGD:1353234 6480464 Gallic Acid results in decreased expression of XRCC4 mRNA CTD PMID:34408198 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of XRCC4 mRNA CTD PMID:33387578 hydroxyurea decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Hydroxyurea CTD PMID:21785230 irinotecan decreases expression ISO RGD:1353234 6480464 Irinotecan metabolite results in decreased expression of XRCC4 mRNA, Irinotecan results in decreased expression of XRCC4 mRNA CTD PMID:15956246 ivermectin decreases expression ISO RGD:1353234 6480464 Ivermectin results in decreased expression of XRCC4 protein CTD PMID:32959892 lead(0) affects expression ISO RGD:1353234 6480464 Lead affects the expression of XRCC4 mRNA CTD PMID:22313790 lead(0) affects response to substance ISO RGD:1353234 6480464 XRCC4 gene polymorphism affects the susceptibility to Lead CTD PMID:22466227 lithium chloride increases expression EXP 6480464 Lithium Chloride results in increased expression of XRCC4 mRNA CTD PMID:19285016 methyl methanesulfonate decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Methyl Methanesulfonate CTD PMID:21785230 mitomycin C decreases response to substance ISO RGD:1353234 6480464 XRCC4 results in decreased susceptibility to Mitomycin CTD PMID:21785230 monocrotaline multiple interactions ISO RGD:1550337 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 N-Nitrosopyrrolidine decreases expression ISO RGD:1353234 6480464 N-Nitrosopyrrolidine results in decreased expression of XRCC4 mRNA CTD PMID:32234424 nickel atom increases expression ISO RGD:1353234 6480464 Nickel results in increased expression of XRCC4 mRNA CTD PMID:25583101 nickel dichloride increases expression ISO RGD:1353234 6480464 nickel chloride results in increased expression of XRCC4 protein CTD PMID:28472268 nickel dichloride affects expression ISO RGD:1353234 6480464 nickel chloride affects the expression of XRCC4 mRNA CTD PMID:28472268 O-methyleugenol decreases expression ISO RGD:1353234 6480464 methyleugenol results in decreased expression of XRCC4 mRNA CTD PMID:32234424 okadaic acid increases expression ISO RGD:1550337 6480464 Okadaic Acid results in increased expression of XRCC4 mRNA CTD PMID:25270620 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of XRCC4 mRNA CTD PMID:25729387 paracetamol affects expression ISO RGD:1550337 6480464 Acetaminophen affects the expression of XRCC4 mRNA CTD PMID:29540258 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of XRCC4 mRNA CTD PMID:33387578 paracetamol decreases expression ISO RGD:1353234 6480464 Acetaminophen results in decreased expression of XRCC4 mRNA CTD PMID:29067470 pentachlorophenol increases expression ISO RGD:1353234 6480464 Pentachlorophenol results in increased expression of XRCC4 mRNA CTD PMID:18486366 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1550337 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of XRCC4 mRNA CTD PMID:36331819 phenobarbital affects expression ISO RGD:1550337 6480464 Phenobarbital affects the expression of XRCC4 mRNA CTD PMID:19136022 phenytoin multiple interactions ISO RGD:1550337 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 pirinixic acid affects expression ISO RGD:1550337 6480464 pirinixic acid affects the expression of XRCC4 mRNA CTD PMID:19136022 pirinixic acid increases expression ISO RGD:1550337 6480464 pirinixic acid results in increased expression of XRCC4 mRNA CTD PMID:18301758 , PMID:23811191 potassium chromate decreases expression ISO RGD:1353234 6480464 potassium chromate(VI) results in decreased expression of XRCC4 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:1353234 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of XRCC4 mRNA, epigallocatechin gallate inhibits the reaction [potassium chromate(VI) results in decreased expression of XRCC4 mRNA] CTD PMID:22079256 progesterone increases expression ISO RGD:1353234 6480464 Progesterone results in increased expression of XRCC4 mRNA CTD PMID:18070364 rac-lactic acid decreases expression ISO RGD:1353234 6480464 Lactic Acid results in decreased expression of XRCC4 mRNA CTD PMID:30851411 rifampicin multiple interactions ISO RGD:1550337 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 sodium arsenite decreases expression ISO RGD:1550337 6480464 sodium arsenite results in decreased expression of XRCC4 mRNA CTD PMID:25787150 taurine increases expression ISO RGD:1353234 6480464 Taurine results in increased expression of XRCC4 mRNA CTD PMID:16579726 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of XRCC4 mRNA CTD PMID:25729387 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of XRCC4 mRNA CTD PMID:30589522 valproic acid affects expression ISO RGD:1550337 6480464 Valproic Acid affects the expression of XRCC4 mRNA CTD PMID:17963808 valproic acid affects expression ISO RGD:1353234 6480464 Valproic Acid affects the expression of XRCC4 mRNA CTD PMID:25979313 vorinostat increases expression ISO RGD:1353234 6480464 vorinostat results in increased expression of XRCC4 mRNA CTD PMID:27188386 zinc atom decreases expression ISO RGD:1353234 6480464 Zinc deficiency results in decreased expression of XRCC4 mRNA CTD PMID:18356318 zinc(0) decreases expression ISO RGD:1353234 6480464 Zinc deficiency results in decreased expression of XRCC4 mRNA CTD PMID:18356318