Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ska3 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of SKA3 mRNA | CTD | PMID:30723492 | Ska3 | Rat | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of SKA3 mRNA | CTD | PMID:32145629 | Ska3 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Ska3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Ska3 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Ska3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Ska3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | SKA3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SKA3 mRNA | CTD | PMID:22574217 | Ska3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SKA3 mRNA | CTD | PMID:34747641 | Ska3 | Rat | 2-palmitoylglycerol | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of SKA3 mRNA | CTD | PMID:37199045 | Ska3 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of SKA3 mRNA | CTD | PMID:31881176 | Ska3 | Rat | acrylamide | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SKA3 mRNA | CTD | PMID:32763439 | Ska3 | Rat | aflatoxin B1 | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of SKA3 mRNA | CTD | PMID:22100608 | Ska3 | Rat | aflatoxin B1 | increases methylation | ISO | SKA3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SKA3 gene | CTD | PMID:27153756 | Ska3 | Rat | all-trans-retinoic acid | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SKA3 mRNA | CTD | PMID:33167477 | Ska3 | Rat | arsenous acid | increases expression | ISO | Ska3 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of SKA3 mRNA | CTD | PMID:35676786 | Ska3 | Rat | atrazine | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SKA3 mRNA | CTD | PMID:22378314 | Ska3 | Rat | benzo[a]pyrene | increases methylation | ISO | SKA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SKA3 3' UTR | CTD | PMID:27901495 | Ska3 | Rat | benzo[a]pyrene | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SKA3 mRNA | CTD | PMID:32234424 | Ska3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Ska3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SKA3 mRNA | CTD | PMID:25181051 | Ska3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SKA3 mRNA | CTD | PMID:32145629 | Ska3 | Rat | bisphenol A | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SKA3 mRNA | CTD | PMID:29275510 | Ska3 | Rat | cadmium atom | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SKA3 mRNA | CTD | PMID:35301059 | Ska3 | Rat | cadmium dichloride | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of SKA3 mRNA | CTD | PMID:38568856 | Ska3 | Rat | cadmium dichloride | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SKA3 mRNA | CTD | PMID:35301059 | Ska3 | Rat | caffeine | increases phosphorylation | ISO | SKA3 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of SKA3 protein | CTD | PMID:35688186 | Ska3 | Rat | calcitriol | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of SKA3 mRNA | CTD | PMID:21592394 | Ska3 | Rat | calcitriol | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of SKA3 mRNA | CTD | PMID:21592394 | Ska3 | Rat | carbon nanotube | increases expression | ISO | Ska3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Ska3 | Rat | chlorpyrifos | decreases expression | ISO | Ska3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SKA3 mRNA | CTD | PMID:37019170 | Ska3 | Rat | chromium(6+) | affects expression | ISO | Ska3 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of SKA3 mRNA | CTD | PMID:28472532 | Ska3 | Rat | chromium(6+) | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of SKA3 mRNA | CTD | PMID:38479592 | Ska3 | Rat | copper(II) sulfate | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SKA3 mRNA | CTD | PMID:19549813 | Ska3 | Rat | coumestrol | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of SKA3 mRNA | CTD | PMID:19167446 | Ska3 | Rat | coumestrol | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | Ska3 | Rat | DDE | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of SKA3 mRNA | CTD | PMID:38568856 | Ska3 | Rat | diarsenic trioxide | increases expression | ISO | Ska3 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of SKA3 mRNA | CTD | PMID:35676786 | Ska3 | Rat | Enterolactone | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SKA3 mRNA | CTD | PMID:19167446 | Ska3 | Rat | enzyme inhibitor | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SKA3 protein | CTD | PMID:23301498 | Ska3 | Rat | ethanol | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of SKA3 mRNA | CTD | PMID:29432896 | Ska3 | Rat | folic acid | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of SKA3 mRNA | CTD | PMID:24657277 | Ska3 | Rat | FR900359 | affects phosphorylation | ISO | SKA3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SKA3 protein | CTD | PMID:37730182 | Ska3 | Rat | hydrogen peroxide | affects expression | ISO | SKA3 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of SKA3 mRNA | CTD | PMID:23410634 | Ska3 | Rat | lead(0) | affects expression | ISO | SKA3 (Homo sapiens) | 6480464 | Lead affects the expression of SKA3 mRNA | CTD | PMID:28903495 | Ska3 | Rat | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of SKA3 mRNA | CTD | PMID:35283115 | Ska3 | Rat | menadione | affects expression | ISO | SKA3 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of SKA3 mRNA | CTD | PMID:23410634 | Ska3 | Rat | methotrexate | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of SKA3 mRNA | CTD | PMID:17400583 and PMID:24657277 | Ska3 | Rat | methotrexate | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of SKA3 mRNA | CTD | PMID:24657277 | Ska3 | Rat | N-Nitrosopyrrolidine | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of SKA3 mRNA | CTD | PMID:32234424 | Ska3 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of SKA3 mRNA | CTD | PMID:25729387 | Ska3 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of SKA3 mRNA | CTD | PMID:25729387 | Ska3 | Rat | ozone | multiple interactions | ISO | Ska3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SKA3 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SKA3 mRNA | CTD | PMID:34911549 | Ska3 | Rat | paracetamol | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SKA3 mRNA | CTD | PMID:22230336 | Ska3 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SKA3 mRNA | CTD | PMID:33387578 | Ska3 | Rat | paracetamol | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SKA3 mRNA | CTD | PMID:29067470 | Ska3 | Rat | PCB138 | multiple interactions | ISO | Ska3 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Ska3 | Rat | perfluorooctanoic acid | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of SKA3 mRNA | CTD | PMID:36326898 | Ska3 | Rat | phenethyl isothiocyanate | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | phenethyl isothiocyanate results in decreased expression of SKA3 mRNA | CTD | PMID:26678675 | Ska3 | Rat | resveratrol | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of SKA3 mRNA | CTD | PMID:19167446 | Ska3 | Rat | silicon dioxide | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SKA3 mRNA | CTD | PMID:23806026 | Ska3 | Rat | silicon dioxide | increases expression | ISO | Ska3 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of SKA3 mRNA | CTD | PMID:29341224 | Ska3 | Rat | sodium arsenite | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SKA3 mRNA | CTD | PMID:25493608 and PMID:29301061 | Ska3 | Rat | sodium arsenite | increases expression | ISO | Ska3 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of SKA3 mRNA | CTD | PMID:37682722 | Ska3 | Rat | sodium arsenite | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SKA3 mRNA | CTD | PMID:38568856 | Ska3 | Rat | sunitinib | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SKA3 mRNA | CTD | PMID:31533062 | Ska3 | Rat | temozolomide | increases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of SKA3 mRNA | CTD | PMID:31758290 | Ska3 | Rat | tert-butyl hydroperoxide | affects expression | ISO | SKA3 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide affects the expression of SKA3 mRNA | CTD | PMID:23410634 | Ska3 | Rat | testosterone | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of SKA3 mRNA | CTD | PMID:21592394 | Ska3 | Rat | testosterone | multiple interactions | ISO | SKA3 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of SKA3 mRNA | CTD | PMID:21592394 | Ska3 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SKA3 mRNA | CTD | PMID:34492290 | Ska3 | Rat | thiram | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Thiram results in decreased expression of SKA3 mRNA | CTD | PMID:38568856 | Ska3 | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of SKA3 mRNA | CTD | PMID:25729387 | Ska3 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of SKA3 mRNA | CTD | PMID:25729387 | Ska3 | Rat | trovafloxacin | decreases expression | ISO | Ska3 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of SKA3 mRNA | CTD | PMID:35537566 | Ska3 | Rat | valproic acid | decreases expression | ISO | SKA3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SKA3 mRNA | CTD | PMID:23179753 and PMID:27188386 | |