Fzd1 (frizzled class receptor 1) - Rat Genome Database

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Gene: Fzd1 (frizzled class receptor 1) Rattus norvegicus
Analyze
Symbol: Fzd1
Name: frizzled class receptor 1
RGD ID: 61916
Description: Enables protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including cellular response to vitamin D; lung alveolus development; and positive regulation of DNA-binding transcription factor activity. Located in neuron projection and plasma membrane. Orthologous to human FZD1 (frizzled class receptor 1); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 1; frizzled family receptor 1; frizzled homolog 1; frizzled homolog 1 (Drosophila); frizzled homolog 1, (Drosophila); frizzled-1; fz-1; rFz1
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2429,310,303 - 29,314,701 (+)NCBImRatBN7.2
Rnor_6.0426,470,864 - 26,475,262 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl426,470,864 - 26,475,262 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0426,377,857 - 26,382,255 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,994,423 - 25,998,821 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1426,006,310 - 26,010,460 (+)NCBI
Celera424,743,049 - 24,747,447 (+)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-colchicine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
adenine  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
cisplatin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
dieldrin  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
ethanol  (ISO)
ethosuximide  (EXP)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
genistein  (EXP)
gentamycin  (EXP)
hydroxyurea  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nickel atom  (EXP,ISO)
niclosamide  (ISO)
nitrofen  (EXP)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorononanoic acid  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
Ptaquiloside  (ISO)
pyrimidifen  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte-dopaminergic neuron signaling  (ISO)
autocrine signaling  (ISO)
canonical Wnt signaling pathway  (IBA,IDA,ISO)
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation  (ISO)
canonical Wnt signaling pathway involved in osteoblast differentiation  (ISO)
cell-cell signaling  (ISO)
cellular response to growth factor stimulus  (IEP)
cellular response to peptide hormone stimulus  (IEP)
cellular response to vitamin D  (IEP)
endothelial cell differentiation  (ISO)
epithelial cell differentiation  (ISO)
G protein-coupled receptor signaling pathway  (IEA)
hard palate development  (ISO)
lung alveolus development  (IEP)
membranous septum morphogenesis  (ISO)
muscular septum morphogenesis  (ISO)
negative regulation of BMP signaling pathway  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of oxidative stress-induced neuron death  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
outflow tract morphogenesis  (ISO)
planar cell polarity pathway involved in neural tube closure  (ISO)
positive regulation of DNA-binding transcription factor activity  (IDA,ISO)
positive regulation of neuron projection development  (IDA)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
regulation of osteoblast differentiation  (IEP)
regulation of presynapse assembly  (ISO)
response to xenobiotic stimulus  (ISO)
ventricular septum morphogenesis  (ISO)
Wnt signaling pathway  (IDA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10395542   PMID:10557084   PMID:11433302   PMID:14627707   PMID:14739301   PMID:15143170   PMID:15809042   PMID:16936075   PMID:18521822   PMID:18929644   PMID:19188438   PMID:19388021  
PMID:19421142   PMID:19643732   PMID:20039315   PMID:20940229   PMID:21423176   PMID:21752258   PMID:28733458  


Genomics

Comparative Map Data
Fzd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2429,310,303 - 29,314,701 (+)NCBImRatBN7.2
Rnor_6.0426,470,864 - 26,475,262 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl426,470,864 - 26,475,262 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0426,377,857 - 26,382,255 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,994,423 - 25,998,821 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1426,006,310 - 26,010,460 (+)NCBI
Celera424,743,049 - 24,747,447 (+)NCBICelera
Cytogenetic Map4q13NCBI
FZD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38791,264,433 - 91,271,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl791,264,433 - 91,271,326 (+)EnsemblGRCh38hg38GRCh38
GRCh37790,893,748 - 90,900,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36790,731,719 - 90,736,068 (+)NCBINCBI36hg18NCBI36
Build 34790,538,433 - 90,542,783NCBI
Celera785,598,534 - 85,602,883 (+)NCBI
Cytogenetic Map7q21.13NCBI
HuRef785,501,893 - 85,506,245 (+)NCBIHuRef
CHM1_1790,823,675 - 90,828,024 (+)NCBICHM1_1
T2T-CHM13v2.0792,512,278 - 92,519,169 (+)NCBI
CRA_TCAGchr7v2790,224,254 - 90,228,603 (+)NCBI
Fzd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3954,803,839 - 4,808,216 (-)NCBIGRCm39mm39
GRCm39 Ensembl54,803,839 - 4,808,035 (-)Ensembl
GRCm3854,753,839 - 4,758,216 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl54,753,839 - 4,758,035 (-)EnsemblGRCm38mm10GRCm38
MGSCv3754,753,839 - 4,758,216 (-)NCBIGRCm37mm9NCBIm37
MGSCv3654,759,845 - 4,763,977 (-)NCBImm8
Celera54,685,028 - 4,689,405 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.61NCBI
FZD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1796,805,227 - 96,876,188 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0783,269,906 - 83,277,608 (+)NCBIMhudiblu_PPA_v0panPan3
FZD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11417,046,911 - 17,050,515 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1417,047,382 - 17,049,337 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1416,617,442 - 16,624,391 (+)NCBI
ROS_Cfam_1.01416,853,072 - 16,860,019 (+)NCBI
ROS_Cfam_1.0 Ensembl1416,853,171 - 16,855,126 (+)Ensembl
UMICH_Zoey_3.11417,015,222 - 17,022,169 (+)NCBI
UNSW_CanFamBas_1.01416,732,649 - 16,739,601 (+)NCBI
UU_Cfam_GSD_1.01417,018,787 - 17,025,738 (+)NCBI
Fzd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511830,465,239 - 30,469,955 (+)NCBI
SpeTri2.0NW_0049366212,899,183 - 2,903,427 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FZD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl971,349,988 - 71,352,104 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1971,346,994 - 71,356,488 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FZD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12157,695,000 - 57,702,666 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2157,699,468 - 57,701,417 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604246,532,184 - 46,537,450 (+)NCBIVero_WHO_p1.0
Fzd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248092,021,124 - 2,025,589 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248092,021,118 - 2,025,826 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AW227548  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,314,063 - 29,314,209 (+)MAPPERmRatBN7.2
Rnor_6.0426,474,625 - 26,474,770NCBIRnor6.0
Rnor_5.0426,381,618 - 26,381,763UniSTSRnor5.0
RGSC_v3.4425,998,184 - 25,998,329UniSTSRGSC3.4
Celera424,746,810 - 24,746,955UniSTS
Cytogenetic Map4q13UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:883
Count of miRNA genes:316
Interacting mature miRNAs:419
Transcripts:ENSRNOT00000021979
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 40 10 8 11 8 55 35 33 11
Low 3 3 47 33 8 33 8 11 19 6 8
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000021979   ⟹   ENSRNOP00000021979
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl426,470,864 - 26,475,262 (+)Ensembl
RefSeq Acc Id: NM_021266   ⟹   NP_067089
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2429,310,303 - 29,314,701 (+)NCBI
Rnor_6.0426,470,864 - 26,475,262 (+)NCBI
Rnor_5.0426,377,857 - 26,382,255 (+)NCBI
RGSC_v3.4425,994,423 - 25,998,821 (+)RGD
Celera424,743,049 - 24,747,447 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_067089 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84350 (Get FASTA)   NCBI Sequence Viewer  
  Q08463 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_067089   ⟸   NM_021266
- Peptide Label: precursor
- UniProtKB: G3V833 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021979   ⟸   ENSRNOT00000021979
Protein Domains
FZ   G_PROTEIN_RECEP_F2_4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08463-F1-model_v2 AlphaFold Q08463 1-641 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692840
Promoter ID:EPDNEW_R3365
Type:initiation region
Name:Fzd1_1
Description:frizzled class receptor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0426,470,867 - 26,470,927EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61916 AgrOrtholog
BioCyc Gene G2FUF-45785 BioCyc
Ensembl Genes ENSRNOG00000016242 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021979 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021979 UniProtKB/TrEMBL
Gene3D-CATH 1.10.2000.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Frizzled/SFRP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frizzled/Smoothened_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frizzled_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frizzled_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FZD1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:58868 UniProtKB/TrEMBL
NCBI Gene 58868 ENTREZGENE
PANTHER PTHR11309 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11309:SF34 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Frizzled UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF01392 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fzd1 PhenoGen
PRINTS FRIZZLED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50038 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FRI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frizzled UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF63501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC205498
UniProt FZD1_RAT UniProtKB/Swiss-Prot
  G3V833 ENTREZGENE, UniProtKB/TrEMBL
  Q08463 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-02-06 Fzd1  frizzled class receptor 1  Fzd1  frizzled family receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Fzd1  frizzled family receptor 1  Fzd1  frizzled homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Fzd1  frizzled homolog 1 (Drosophila)      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression widely expressed 61590
gene_protein 641 amino acids 61590