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Gene: Fzd1 (frizzled class receptor 1) Rattus norvegicus
Symbol: Fzd1
Name: frizzled class receptor 1
Description: Exhibits protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including cellular response to vitamin D; lung alveolus development; and positive regulation of DNA-binding transcription factor activity. Localizes to neuron projection and plasma membrane. Orthologous to human FZD1 (frizzled class receptor 1); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 1; frizzled family receptor 1; frizzled homolog 1; frizzled homolog 1 (Drosophila); frizzled homolog 1, (Drosophila); frizzled-1; fz-1; rFz1
Homo sapiens (human) : FZD1 (frizzled class receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Fzd1 (frizzled class receptor 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FZD1 (frizzled class receptor 1)
Canis lupus familiaris (dog) : FZD1 (frizzled class receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fzd1 (frizzled class receptor 1)
Sus scrofa (pig) : FZD1 (frizzled class receptor 1)
Chlorocebus sabaeus (African green monkey) : FZD1 (frizzled class receptor 1)
Heterocephalus glaber (naked mole-rat) : Fzd1 (frizzled class receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0426,470,864 - 26,475,262 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl426,470,864 - 26,475,262 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0426,377,857 - 26,382,255 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,994,423 - 25,998,821 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1426,006,310 - 26,010,460 (+)NCBI
Celera424,743,049 - 24,747,447 (+)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fzd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61916
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.