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Gene: Epha4 (Eph receptor A4) Rattus norvegicus
Symbol: Epha4
Name: Eph receptor A4
Description: Exhibits ephrin receptor binding activity. Involved in several processes, including neurogenesis; regulation of modification of synaptic structure; and synapse pruning. Localizes to several cellular components, including dendrite; distal axon; and perikaryon. Biomarker of toxic encephalopathy. Orthologous to human EPHA4 (EPH receptor A4); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ephrin type-A receptor 4; LOC316539; RGD1560587; similar to Eph receptor A4
Homo sapiens (human) : EPHA4 (EPH receptor A4)  HGNC  Alliance
Mus musculus (house mouse) : Epha4 (Eph receptor A4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epha4 (EPH receptor A4)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHA4 (EPH receptor A4)
Canis lupus familiaris (dog) : EPHA4 (EPH receptor A4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epha4 (EPH receptor A4)
Sus scrofa (pig) : EPHA4 (EPH receptor A4)
Chlorocebus sabaeus (African green monkey) : EPHA4 (EPH receptor A4)
Heterocephalus glaber (naked mole-rat) : Epha4 (EPH receptor A4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0983,111,222 - 83,253,486 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl983,111,222 - 83,253,458 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0982,880,599 - 83,022,444 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4976,676,778 - 76,820,752 (-)NCBIRGSC3.4rn4RGSC3.4
Celera976,344,796 - 76,487,530 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Epha4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560587
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.