Thbs4 (thrombospondin 4) - Rat Genome Database

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Gene: Thbs4 (thrombospondin 4) Rattus norvegicus
Analyze
Symbol: Thbs4
Name: thrombospondin 4
RGD ID: 62046
Description: Enables several functions, including fibronectin binding activity; identical protein binding activity; and laminin-1 binding activity. Involved in behavioral response to pain and neuron projection morphogenesis. Located in neuromuscular junction. Orthologous to human THBS4 (thrombospondin 4); PARTICIPATES IN cell-extracellular matrix signaling pathway; malaria pathway; phagocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: thrombospondin-4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2223,983,158 - 24,025,289 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl223,983,158 - 24,026,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx231,012,074 - 31,054,079 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0229,112,424 - 29,154,423 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0223,940,916 - 23,982,917 (-)NCBIRnor_WKY
Rnor_6.0222,343,727 - 22,385,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl222,343,727 - 22,385,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0241,549,115 - 41,591,101 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4223,010,823 - 23,053,527 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1222,931,199 - 22,973,881 (-)NCBI
Celera220,070,701 - 20,112,733 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(E)-thiamethoxam  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enalapril  (ISO)
ethanol  (ISO)
etoposide  (ISO)
flavonoids  (EXP)
furan  (EXP)
furosemide  (EXP)
isotretinoin  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
mercaptopurine  (EXP)
mercury dichloride  (EXP)
methyl salicylate  (ISO)
metoprolol  (EXP)
milrinone  (EXP)
paracetamol  (EXP)
pentane-2,3-dione  (EXP)
phenylmercury acetate  (ISO)
phthalaldehyde  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
purine-6-thiol  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thiamethoxam  (ISO)
titanium dioxide  (ISO)
triazines  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Thrombospondin-4, an extracellular matrix protein expressed in the developing and adult nervous system promotes neurite outgrowth. Arber S and Caroni P, J Cell Biol 1995 Nov;131(4):1083-94.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states. Kim DS, etal., J Neurosci. 2012 Jun 27;32(26):8977-87. doi: 10.1523/JNEUROSCI.6494-11.2012.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Thrombospondin-4 binds specifically to both collagenous and non-collagenous extracellular matrix proteins via its C-terminal domains. Narouz-Ott L, etal., J Biol Chem. 2000 Nov 24;275(47):37110-7.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
13. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. van Doorn R, etal., J Clin Oncol. 2005 Jun 10;23(17):3886-96. Epub 2005 May 16.
Additional References at PubMed
PMID:7519904   PMID:7852353   PMID:12952849   PMID:16099885   PMID:16246837   PMID:17882701   PMID:17927980   PMID:18541142   PMID:18802666   PMID:19182904   PMID:19571575   PMID:19818485  
PMID:22362893   PMID:22682248   PMID:23533145   PMID:23649982   PMID:25327416   PMID:26459760   PMID:27160673   PMID:27581066   PMID:27647309   PMID:28232180  


Genomics

Comparative Map Data
Thbs4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2223,983,158 - 24,025,289 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl223,983,158 - 24,026,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx231,012,074 - 31,054,079 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0229,112,424 - 29,154,423 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0223,940,916 - 23,982,917 (-)NCBIRnor_WKY
Rnor_6.0222,343,727 - 22,385,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl222,343,727 - 22,385,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0241,549,115 - 41,591,101 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4223,010,823 - 23,053,527 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1222,931,199 - 22,973,881 (-)NCBI
Celera220,070,701 - 20,112,733 (-)NCBICelera
Cytogenetic Map2q12NCBI
THBS4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38579,991,332 - 80,083,287 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl579,991,311 - 80,083,287 (+)EnsemblGRCh38hg38GRCh38
GRCh37579,287,155 - 79,379,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36579,366,747 - 79,414,866 (+)NCBINCBI36Build 36hg18NCBI36
Build 34579,366,746 - 79,414,861NCBI
Celera575,232,509 - 75,280,442 (+)NCBICelera
Cytogenetic Map5q14.1NCBI
HuRef574,539,053 - 74,586,983 (+)NCBIHuRef
CHM1_1578,764,258 - 78,812,159 (+)NCBICHM1_1
T2T-CHM13v2.0580,475,183 - 80,567,137 (+)NCBIT2T-CHM13v2.0
Thbs4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391392,888,094 - 92,931,326 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1392,888,098 - 92,931,326 (-)EnsemblGRCm39 Ensembl
GRCm381392,751,586 - 92,794,818 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1392,751,590 - 92,794,818 (-)EnsemblGRCm38mm10GRCm38
MGSCv371393,521,541 - 93,564,773 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361393,852,339 - 93,895,511 (-)NCBIMGSCv36mm8
Celera1396,355,385 - 96,398,324 (-)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1347.75NCBI
Thbs4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542521,069,855 - 21,117,061 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542521,072,873 - 21,117,061 (-)NCBIChiLan1.0ChiLan1.0
THBS4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1533,377,268 - 33,469,098 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0535,232,459 - 35,324,613 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1535,505,370 - 35,553,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl535,505,375 - 35,553,040 (-)Ensemblpanpan1.1panPan2
THBS4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1326,945,001 - 26,982,224 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl326,945,081 - 26,988,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha328,184,781 - 28,226,829 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0326,864,062 - 26,906,077 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl326,864,144 - 26,906,081 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1326,803,818 - 26,845,793 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0326,780,744 - 26,822,700 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0327,060,242 - 27,102,310 (-)NCBIUU_Cfam_GSD_1.0
Thbs4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213183,030,397 - 183,077,597 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365497,780,842 - 7,829,379 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365497,781,214 - 7,828,569 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THBS4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl288,726,687 - 88,780,751 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1288,729,531 - 88,780,759 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2290,502,359 - 90,549,528 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THBS4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1474,195,487 - 74,275,723 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl474,234,261 - 74,275,775 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604923,076,969 - 23,123,257 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thbs4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248694,553,194 - 4,601,587 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248694,553,192 - 4,601,076 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Thbs4
195 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:81
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000065224
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat

Markers in Region
RH131881  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2223,983,267 - 23,983,944 (+)MAPPERmRatBN7.2
Rnor_6.0222,343,837 - 22,344,513NCBIRnor6.0
Rnor_5.0241,549,225 - 41,549,901UniSTSRnor5.0
RGSC_v3.4223,010,938 - 23,011,614UniSTSRGSC3.4
Celera220,070,811 - 20,071,487UniSTS
Cytogenetic Map2q12UniSTS
THBS4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2223,994,209 - 23,994,558 (+)MAPPERmRatBN7.2
Rnor_6.0222,354,778 - 22,355,126NCBIRnor6.0
Rnor_5.0241,560,024 - 41,560,372UniSTSRnor5.0
RGSC_v3.4223,022,622 - 23,022,970UniSTSRGSC3.4
Celera220,081,681 - 20,082,029UniSTS
Cytogenetic Map2q12UniSTS
UniSTS:496018  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2224,021,141 - 24,021,204 (+)MAPPERmRatBN7.2
Rnor_6.0222,381,707 - 22,381,769NCBIRnor6.0
Rnor_5.0241,586,953 - 41,587,015UniSTSRnor5.0
RGSC_v3.4223,049,553 - 23,049,615UniSTSRGSC3.4
Celera220,108,587 - 20,108,649UniSTS
Cytogenetic Map2q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 1 8 11 7 8
Low 3 35 38 32 13 32 44 35 21 8
Below cutoff 19 9 5 9 30 12 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000065224   ⟹   ENSRNOP00000062272
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl223,983,158 - 24,026,313 (-)Ensembl
Rnor_6.0 Ensembl222,343,730 - 22,385,676 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083531   ⟹   ENSRNOP00000074259
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl223,983,158 - 24,025,289 (-)Ensembl
Rnor_6.0 Ensembl222,343,727 - 22,385,855 (-)Ensembl
RefSeq Acc Id: NM_017133   ⟹   NP_058829
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2223,983,158 - 24,025,289 (-)NCBI
Rnor_6.0222,343,727 - 22,385,855 (-)NCBI
Rnor_5.0241,549,115 - 41,591,101 (-)NCBI
Celera220,070,701 - 20,112,733 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_058829 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10025 (Get FASTA)   NCBI Sequence Viewer  
  P49744 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058829   ⟸   NM_017133
- Peptide Label: precursor
- UniProtKB: A0A0G2K7L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000062272   ⟸   ENSRNOT00000065224
RefSeq Acc Id: ENSRNOP00000074259   ⟸   ENSRNOT00000083531
Protein Domains
EGF-like   Laminin G-like   TSP C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49744-F1-model_v2 AlphaFold P49744 1-980 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691063
Promoter ID:EPDNEW_R1587
Type:multiple initiation site
Name:Thbs4_1
Description:thrombospondin 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0222,385,834 - 22,385,894EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62046 AgrOrtholog
BioCyc Gene G2FUF-54861 BioCyc
Ensembl Genes ENSRNOG00000012471 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000062272.2 UniProtKB/TrEMBL
  ENSRNOP00000074259 ENTREZGENE
  ENSRNOP00000074259.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065224.2 UniProtKB/TrEMBL
  ENSRNOT00000083531 ENTREZGENE
  ENSRNOT00000083531.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.1080.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thbs/COMP_coiled-coil UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thrombospondin_3-like_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thrombospondin_3_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thrombospondin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP/COMP_coiled-coil_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP_type-3_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29220 UniProtKB/TrEMBL
NCBI Gene 29220 ENTREZGENE
PANTHER THROMBOSPONDIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THROMBOSPONDIN-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Thbs4 PhenoGen
PROSITE EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Assembly domain of cartilage oligomeric matrix protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF103647 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218842
UniProt A0A0G2K7L8 ENTREZGENE, UniProtKB/TrEMBL
  F1LMS5_RAT UniProtKB/TrEMBL
  P49744 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Thbs4  thrombospondin 4       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized in the extracellular matrix at the neuromuscular junction 61768
gene_process promotes neurite outgrowth 61768