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Gene: Hmgb2 (high mobility group box 2) Rattus norvegicus
Symbol: Hmgb2
Name: high mobility group box 2
Description: Exhibits lipid binding activity and nucleosomal histone binding activity. Involved in animal organ regeneration; nervous system development; and positive regulation of nucleobase-containing compound metabolic process. Localizes to nucleus. Orthologous to human HMGB2 (high mobility group box 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: high mobility group protein 2; high mobility group protein B2; HMG-2; Hmg2; MGC108899; MGC125103
Homo sapiens (human) : HMGB2 (high mobility group box 2)  HGNC  Alliance
Mus musculus (house mouse) : Hmgb2 (high mobility group box 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmgb2 (high mobility group box 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HMGB2 (high mobility group box 2)
Canis lupus familiaris (dog) : HMGB2 (high mobility group box 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmgb2 (high mobility group box 2)
Sus scrofa (pig) : HMGB2 (high mobility group box 2)
Chlorocebus sabaeus (African green monkey) : HMGB2 (high mobility group box 2)
Heterocephalus glaber (naked mole-rat) : Hmgb2 (high mobility group box 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01636,077,615 - 36,080,191 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1636,077,617 - 36,080,191 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1149,708,407 - 49,709,039 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01635,886,762 - 35,889,338 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41636,131,304 - 36,133,878 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11636,131,383 - 36,133,868 (-)NCBI
Celera1632,658,338 - 32,660,913 (-)NCBICelera
Cytogenetic Map16p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hmgb2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69291
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.