Gene: Jak2 (Janus kinase 2) Rattus norvegicus
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Symbol: Jak2
Name: Janus kinase 2
Description: ENCODES a protein that exhibits acetylcholine receptor binding; growth hormone receptor binding; insulin receptor substrate binding; INVOLVED IN activation of MAPKK activity; axon regeneration; G protein-coupled receptor signaling pathway; PARTICIPATES IN aldosterone signaling pathway; angiotensin II signaling pathway; angiotensin II signaling pathway via AT1 receptor; ASSOCIATED WITH Brain Injuries; Diabetic Nephropathies; Experimental Arthritis; FOUND IN cytoplasm; cytosol; glutamatergic synapse; INTERACTS WITH (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid; (R)-mevalonic acid; (S)-nicotine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: JAK-2; Janus kinase 2 (a protein tyrosine kinase); tyrosine-protein kinase JAK2
Orthologs:
Homo sapiens (human) : JAK2 (Janus kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Jak2 (Janus kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jak2 (Janus kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : JAK2 (Janus kinase 2)
Canis lupus familiaris (dog) : JAK2 (Janus kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jak2 (Janus kinase 2)
Sus scrofa (pig) : JAK2 (Janus kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01247,398,667 - 247,457,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01254,646,160 - 254,706,478 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,915,995 - 232,974,763 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11233,080,017 - 233,138,786 (+)NCBI
Celera1224,147,256 - 224,206,104 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Jak2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2939
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE