(-)-Arctigenin multiple interactions ISO RGD:10823 6480464 arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:21426947 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:731748 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of JAK2 mRNA CTD PMID:22079256 (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid multiple interactions EXP 6480464 zopolrestat results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 (R)-mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]] CTD PMID:16534557 (S)-nicotine increases response to substance ISO RGD:731748 6480464 JAK2 results in increased susceptibility to Nicotine CTD PMID:20943775 (S)-nicotine multiple interactions EXP 6480464 Bungarotoxins inhibits the reaction [Nicotine results in increased phosphorylation of JAK2 protein] CTD PMID:34153408 (S)-nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of JAK2 protein CTD PMID:34153408 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of JAK2 mRNA CTD PMID:29155039 1,2-dimethylhydrazine decreases expression ISO RGD:10823 6480464 1, 2-Dimethylhydrazine results in decreased expression of JAK2 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:10823 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of JAK2 mRNA] CTD PMID:22206623 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of JAK2 mRNA CTD PMID:25380136 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:10823 6480464 15-deoxy-delta(12 more ... CTD PMID:12847270 17beta-estradiol multiple interactions ISO RGD:731748 6480464 [alpha-cyano-(3 more ... CTD PMID:17272397 more ... 17beta-estradiol increases expression ISO RGD:731748 6480464 Estradiol results in increased expression of JAK2 mRNA CTD PMID:26865669 more ... 17beta-estradiol decreases expression ISO RGD:731748 6480464 Estradiol results in decreased expression of JAK2 mRNA CTD PMID:19619570 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731748 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of JAK2 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of JAK2 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10823 6480464 AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of JAK2 mRNA] CTD PMID:22978700 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10823 6480464 Tetrachlorodibenzodioxin results in decreased expression of JAK2 mRNA CTD PMID:22978700 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10823 6480464 Tetrachlorodibenzodioxin affects the expression of JAK2 mRNA CTD PMID:21570461 , PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of JAK2 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10823 6480464 Tetrachlorodibenzodioxin results in increased expression of JAK2 mRNA CTD PMID:17942748 , PMID:18684927 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731748 6480464 Tetrachlorodibenzodioxin results in decreased expression of JAK2 mRNA CTD PMID:19619570 2,4,6-trinitrobenzenesulfonic acid increases phosphorylation EXP 6480464 Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein CTD PMID:33522063 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein], hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33522063 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation EXP 6480464 4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of JAK2 protein CTD PMID:31231976 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions EXP 6480464 rhyncophylline inhibits the reaction [4-iodo-2 more ... CTD PMID:31231976 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA], IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine results in increased expression of JAK2 mRNA CTD PMID:17109745 2-ethoxyethanol increases expression EXP 6480464 2-ethoxyethanol results in increased expression of JAK2 mRNA CTD PMID:19643169 2-hydroxypropanoic acid decreases expression ISO RGD:731748 6480464 Lactic Acid results in decreased expression of JAK2 mRNA CTD PMID:30851411 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of JAK2 mRNA CTD PMID:19643169 3,4-methylenedioxymethamphetamine increases expression ISO RGD:10823 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of JAK2 mRNA CTD PMID:20188158 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of JAK2 mRNA CTD PMID:28522335 3-methyladenine decreases phosphorylation ISO RGD:731748 149735343 3-methyladenine co-treated with anlotinib decreases phosphorylation of JAK2 protein in lung epithelium RGD 3-methylcholanthrene decreases expression ISO RGD:10823 6480464 Methylcholanthrene results in decreased expression of JAK2 mRNA CTD PMID:22978700 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33522063 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of JAK2 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of JAK2 mRNA CTD PMID:25380136 4-hydroxynon-2-enal decreases expression ISO RGD:10823 6480464 4-hydroxy-2-nonenal results in decreased expression of JAK2 mRNA CTD PMID:19191707 5-aza-2'-deoxycytidine decreases expression ISO RGD:731748 6480464 Decitabine results in decreased expression of JAK2 protein modified form CTD PMID:19379557 5-aza-2'-deoxycytidine multiple interactions ISO RGD:10823 6480464 Decitabine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of JAK2 protein] CTD PMID:24440346 5-aza-2'-deoxycytidine decreases methylation ISO RGD:731748 6480464 Decitabine results in decreased methylation of JAK2 promoter CTD PMID:18055864 abamectin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of JAK2 mRNA] CTD PMID:34748272 abamectin increases expression EXP 6480464 abamectin results in increased expression of JAK2 mRNA CTD PMID:34748272 acetamide increases expression EXP 6480464 acetamide results in increased expression of JAK2 mRNA CTD PMID:31881176 acetic acid multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein], Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:35122774 acetic acid increases phosphorylation EXP 6480464 Acetic Acid results in increased phosphorylation of JAK2 protein CTD PMID:35122774 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 afimoxifene multiple interactions ISO RGD:731748 6480464 afimoxifene promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] CTD PMID:17272397 aflatoxin B1 increases expression ISO RGD:10823 6480464 Aflatoxin B1 results in increased expression of JAK2 mRNA CTD PMID:19770486 aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA], IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of JAK2 mRNA CTD PMID:17109745 aldehydo-D-glucose multiple interactions ISO RGD:731748 6480464 (3 more ... CTD PMID:15677497 aldehydo-D-glucose multiple interactions EXP 6480464 alpha-cyano-(3, 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein] CTD PMID:20060012 aldehydo-D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of JAK2 protein CTD PMID:20060012 aldosterone increases phosphorylation EXP 6480464 Aldosterone results in increased phosphorylation of JAK2 protein CTD PMID:15932931 aldosterone multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein], Spironolactone inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 all-trans-retinoic acid increases expression ISO RGD:731748 6480464 Tretinoin results in increased expression of JAK2 mRNA CTD PMID:33167477 all-trans-retinol affects localization EXP 6480464 Vitamin A affects the localization of JAK2 protein CTD PMID:15963505 amlodipine increases expression ISO RGD:731748 6480464 Amlodipine results in increased expression of JAK2 protein modified form CTD PMID:18298949 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of JAK2 mRNA CTD PMID:16483693 angiotensin II increases phosphorylation ISO RGD:731748 127285667 Angiotensin II increases phosphorylation of JAK2 protein in liver RGD antirheumatic drug decreases expression ISO RGD:731748 6480464 Antirheumatic Agents results in decreased expression of JAK2 mRNA CTD PMID:24449571 apocynin multiple interactions ISO RGD:731748 6480464 acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 arecoline increases phosphorylation EXP 6480464 Arecoline results in increased phosphorylation of JAK2 protein CTD PMID:34999050 arsane affects methylation ISO RGD:731748 6480464 Arsenic affects the methylation of JAK2 gene CTD PMID:25304211 arsane increases phosphorylation ISO RGD:731748 6480464 Arsenic results in increased phosphorylation of JAK2 protein CTD PMID:35031324 arsenic atom affects methylation ISO RGD:731748 6480464 Arsenic affects the methylation of JAK2 gene CTD PMID:25304211 arsenic atom increases phosphorylation ISO RGD:731748 6480464 Arsenic results in increased phosphorylation of JAK2 protein CTD PMID:35031324 arsenous acid decreases phosphorylation ISO RGD:731748 6480464 Arsenic Trioxide results in decreased phosphorylation of JAK2 protein CTD PMID:29409467 arsenous acid multiple interactions ISO RGD:731748 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein more ... CTD PMID:12492118 more ... arsenous acid decreases expression ISO RGD:731748 6480464 Arsenic Trioxide results in decreased expression of JAK2 protein CTD PMID:11721366 arsenous acid increases expression ISO RGD:731748 6480464 Arsenic Trioxide results in increased expression of JAK2 mRNA CTD PMID:29633893 auranofin multiple interactions ISO RGD:731748 6480464 [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein CTD PMID:20542334 Bardoxolone methyl multiple interactions ISO RGD:10823 6480464 bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of JAK2 protein] CTD PMID:27417254 baricitinib decreases activity ISO RGD:731748 6480464 baricitinib results in decreased activity of JAK2 protein CTD PMID:29687421 baricitinib multiple interactions ISO RGD:731748 6480464 baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:23968543 benzo[a]pyrene decreases expression ISO RGD:731748 6480464 Benzo(a)pyrene results in decreased expression of JAK2 mRNA CTD PMID:20064835 benzo[a]pyrene increases expression ISO RGD:10823 6480464 Benzo(a)pyrene results in increased expression of JAK2 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:10823 6480464 Benzo(a)pyrene results in decreased expression of JAK2 mRNA CTD PMID:22228805 beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA], IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 beta-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of JAK2 mRNA CTD PMID:17109745 beta-Elemonic acid decreases phosphorylation ISO RGD:731748 6480464 beta-elemonic acid results in decreased phosphorylation of JAK2 protein CTD PMID:33878321 bisphenol A multiple interactions ISO RGD:731748 6480464 [alpha-cyano-(3 more ... CTD PMID:23850738 bisphenol A increases phosphorylation ISO RGD:10823 6480464 bisphenol A results in increased phosphorylation of JAK2 protein CTD PMID:30609183 bisphenol A increases expression ISO RGD:731748 6480464 bisphenol A results in increased expression of JAK2 mRNA CTD PMID:28711546 bisphenol A affects methylation ISO RGD:10823 6480464 bisphenol A affects the methylation of JAK2 promoter CTD PMID:27824486 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of JAK2 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of JAK2 mRNA CTD PMID:25181051 more ... bisphenol F increases phosphorylation ISO RGD:10823 6480464 4, 4'-bisphenol F results in increased phosphorylation of JAK2 protein CTD PMID:32044397 bisphenol F multiple interactions ISO RGD:10823 6480464 alpha-cyano-(3 more ... CTD PMID:32044397 butyric acid decreases expression ISO RGD:731748 6480464 Butyric Acid results in decreased expression of JAK2 mRNA CTD PMID:34581912 cadmium atom multiple interactions ISO RGD:10823 6480464 [Cadmium co-treated with Dietary Fats] results in increased phosphorylation of JAK2 protein CTD PMID:34998821 cadmium dichloride decreases phosphorylation ISO RGD:731748 6480464 Cadmium Chloride results in decreased phosphorylation of JAK2 protein CTD PMID:19635391 calciol increases expression ISO RGD:10823 6480464 Cholecalciferol results in increased expression of JAK2 mRNA CTD PMID:17170073 calcium atom multiple interactions ISO RGD:10823 6480464 JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 calcium(0) multiple interactions ISO RGD:10823 6480464 JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 cannabidiol multiple interactions ISO RGD:731748 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of JAK2 mRNA CTD PMID:30096889 ceruletide multiple interactions ISO RGD:10823 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Ceruletide results in increased expression of JAK2 protein]] more ... CTD PMID:34423886 ceruletide increases expression ISO RGD:10823 6480464 Ceruletide results in increased expression of JAK2 protein CTD PMID:34423886 chelerythrine multiple interactions EXP 6480464 chelerythrine results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 chloroquine decreases phosphorylation ISO RGD:731748 149735343 chloroquine co-treated with anlotinib decreases phosphorylation of JAK2 protein in lung epithelium RGD chlorpyrifos increases phosphorylation ISO RGD:10823 6480464 Chlorpyrifos results in increased phosphorylation of JAK2 protein CTD PMID:29404631 Cirsimarin multiple interactions ISO RGD:10823 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] CTD PMID:30053449 cisplatin increases prenylation ISO RGD:10823 149735351 cisplatin increases phosphorylation of Jak2 protein in kidney RGD cisplatin decreases expression ISO RGD:731748 6480464 Cisplatin results in decreased expression of JAK2 mRNA CTD PMID:27392435 cisplatin decreases phosphorylation ISO RGD:731748 127284886 cisplatin decreases phosphorylation of JAK2 protein in stomach RGD cisplatin increases expression ISO RGD:10823 149735351 cisplatin increases expression of Jak2 mRNA in kidney RGD clomiphene decreases expression ISO RGD:731748 6480464 Clomiphene results in decreased expression of JAK2 mRNA CTD PMID:26865669 clothianidin decreases expression ISO RGD:731748 6480464 clothianidin results in decreased expression of JAK2 mRNA CTD PMID:31626844 clozapine multiple interactions EXP 6480464 [[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein more ... CTD PMID:18976543 cocaine increases phosphorylation ISO RGD:10823 6480464 Cocaine results in increased phosphorylation of JAK2 protein CTD PMID:29673861 cocaine multiple interactions ISO RGD:10823 6480464 alpha-cyano-(3 more ... CTD PMID:29673861 coniferyl aldehyde multiple interactions ISO RGD:10823 6480464 coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:27378624 coniferyl aldehyde multiple interactions ISO RGD:731748 6480464 coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein] CTD PMID:27378624 copper atom multiple interactions ISO RGD:731748 6480464 [Chelating Agents binds to Copper] which results in increased expression of JAK2 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:731748 6480464 [Chelating Agents binds to Copper] which results in increased expression of JAK2 mRNA CTD PMID:30911355 corticosterone multiple interactions EXP 6480464 [alpha-cyano-(3, 4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [HTR2A protein results in increased secretion of Corticosterone] CTD PMID:19304867 coumermycin A1 multiple interactions ISO RGD:10823 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased expression of JAK2 protein]], coumermycin inhibits the reaction [limonin inhibits the reaction [Ceruletide results in increased expression of JAK2 protein]] CTD PMID:34423886 coumermycin A1 increases expression ISO RGD:10823 6480464 coumermycin results in increased expression of JAK2 protein CTD PMID:34423886 crocin-1 multiple interactions ISO RGD:731748 6480464 crocin affects the expression of and affects the phosphorylation of JAK2 protein CTD PMID:32886819 cucurbitacin I multiple interactions ISO RGD:731748 6480464 cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:19153190 Cuprizon multiple interactions ISO RGD:10823 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of JAK2 protein modified form] CTD PMID:29864483 Cuprizon increases expression ISO RGD:10823 6480464 Cuprizone results in increased expression of JAK2 protein modified form CTD PMID:29864483 curcumin decreases expression ISO RGD:731748 6480464 Curcumin results in decreased expression of JAK2 protein CTD PMID:16959222 cyclosporin A increases activity ISO RGD:10823 6480464 Cyclosporine results in increased activity of JAK2 protein CTD PMID:22155090 cyclosporin A increases expression ISO RGD:731748 6480464 Cyclosporine results in increased expression of JAK2 mRNA CTD PMID:20106945 more ... cyclosporin A increases phosphorylation ISO RGD:10823 6480464 Cyclosporine results in increased phosphorylation of JAK2 protein CTD PMID:23958496 cyclosporin A multiple interactions ISO RGD:10823 6480464 sulforaphane inhibits the reaction [Cyclosporine results in increased phosphorylation of JAK2 protein] CTD PMID:23958496 D-glucose multiple interactions ISO RGD:731748 6480464 (3 more ... CTD PMID:15677497 D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of JAK2 protein CTD PMID:20060012 D-glucose multiple interactions EXP 6480464 alpha-cyano-(3, 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein] CTD PMID:20060012 dapagliflozin multiple interactions EXP 6480464 dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein] CTD PMID:34391751 daunorubicin decreases expression ISO RGD:731748 6480464 Daunorubicin results in decreased expression of JAK2 mRNA CTD PMID:26537877 , PMID:28940058 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of JAK2 mRNA CTD PMID:23640034 delphinidin decreases phosphorylation ISO RGD:731748 6480464 delphinidin results in decreased phosphorylation of JAK2 protein CTD PMID:33955636 deoxynivalenol increases expression ISO RGD:10823 6480464 deoxynivalenol results in increased expression of JAK2 mRNA CTD PMID:22454431 deoxynivalenol multiple interactions ISO RGD:10823 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 dextran sulfate multiple interactions ISO RGD:10823 6480464 Erianin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein], Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein] CTD PMID:32272095 dextran sulfate increases phosphorylation ISO RGD:10823 6480464 Dextran Sulfate results in increased phosphorylation of JAK2 protein CTD PMID:32272095 diarsenic trioxide multiple interactions ISO RGD:731748 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein more ... CTD PMID:12492118 more ... diarsenic trioxide increases expression ISO RGD:731748 6480464 Arsenic Trioxide results in increased expression of JAK2 mRNA CTD PMID:29633893 diarsenic trioxide decreases phosphorylation ISO RGD:731748 6480464 Arsenic Trioxide results in decreased phosphorylation of JAK2 protein CTD PMID:29409467 diarsenic trioxide decreases expression ISO RGD:731748 6480464 Arsenic Trioxide results in decreased expression of JAK2 protein CTD PMID:11721366 dibutyl phthalate increases expression ISO RGD:10823 6480464 Dibutyl Phthalate results in increased expression of JAK2 mRNA CTD PMID:21266533 dieldrin decreases expression EXP 6480464 Dieldrin results in decreased expression of JAK2 mRNA CTD PMID:34051100 diethylstilbestrol increases expression ISO RGD:10823 6480464 Diethylstilbestrol results in increased expression of JAK2 mRNA CTD PMID:15591538 diethylstilbestrol increases expression ISO RGD:731748 6480464 Diethylstilbestrol results in increased expression of JAK2 mRNA CTD PMID:26865669 dimethylarsinic acid decreases expression EXP 6480464 Cacodylic Acid results in decreased expression of JAK2 mRNA CTD PMID:17720352 dimethylarsinic acid multiple interactions EXP 6480464 Cacodylic Acid results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:32890875 dioxygen multiple interactions ISO RGD:731748 6480464 alpha-cyano-(3 more ... CTD PMID:29685624 dioxygen increases phosphorylation ISO RGD:731748 6480464 Oxygen deficiency results in increased phosphorylation of JAK2 protein CTD PMID:29685624 divanadium pentaoxide decreases expression ISO RGD:731748 6480464 vanadium pentoxide results in decreased expression of JAK2 mRNA CTD PMID:17459161 doxorubicin decreases expression ISO RGD:731748 6480464 Doxorubicin results in decreased expression of JAK2 mRNA CTD PMID:26537877 more ... doxorubicin increases phosphorylation ISO RGD:10823 6480464 Doxorubicin results in increased phosphorylation of JAK2 protein CTD PMID:34605108 doxorubicin multiple interactions ISO RGD:10823 6480464 Doxorubicin promotes the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein], thymoquinone inhibits the reaction [Doxorubicin results in increased phosphorylation of JAK2 protein] CTD PMID:34605108 emodin decreases phosphorylation ISO RGD:731748 6480464 Emodin results in decreased phosphorylation of JAK2 protein CTD PMID:23848338 emodin multiple interactions ISO RGD:731748 6480464 Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein] CTD PMID:23848338 eriocitrin decreases phosphorylation ISO RGD:731748 6480464 eriocitrin results in decreased phosphorylation of JAK2 protein CTD PMID:34724282 erlotinib hydrochloride decreases phosphorylation ISO RGD:731748 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of JAK2 protein CTD PMID:23894143 estrone increases expression ISO RGD:731748 6480464 Estrone results in increased expression of JAK2 mRNA CTD PMID:26865669 ethanol affects expression ISO RGD:10823 6480464 Ethanol affects the expression of JAK2 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:731748 6480464 Ethyl Methanesulfonate results in increased expression of JAK2 mRNA CTD PMID:23649840 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of JAK2 mRNA CTD PMID:24793618 folic acid multiple interactions ISO RGD:10823 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of JAK2 mRNA] CTD PMID:22206623 folic acid multiple interactions ISO RGD:731748 6480464 alpha-cyano-(3 more ... CTD PMID:29685624 fraxetin decreases phosphorylation ISO RGD:731748 125097526 Fraxetin decreases phosphorylation of JAK2 protein in colorectum RGD fructose decreases phosphorylation EXP 6480464 Fructose results in decreased phosphorylation of JAK2 protein CTD PMID:22426011 fructose multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein], Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] CTD PMID:22426011 fulvestrant decreases expression ISO RGD:731748 6480464 fulvestrant results in decreased expression of JAK2 mRNA CTD PMID:26865669 fulvestrant multiple interactions ISO RGD:10823 6480464 Fulvestrant inhibits the reaction [4, 4'-bisphenol F results in increased phosphorylation of JAK2 protein] CTD PMID:32044397 fulvestrant decreases phosphorylation ISO RGD:10823 6480464 Fulvestrant results in decreased phosphorylation of JAK2 protein CTD PMID:32044397 furan increases methylation EXP 6480464 furan results in increased methylation of JAK2 gene CTD PMID:22079235 galaxolide multiple interactions ISO RGD:731748 6480464 [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of JAK2 mRNA CTD PMID:34687775 galaxolide increases expression ISO RGD:731748 6480464 galaxolide results in increased expression of JAK2 mRNA CTD PMID:34687775 Ganoderic acid A multiple interactions ISO RGD:10823 6480464 ganoderic acid A inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK2 protein] CTD PMID:34029542 genistein increases expression ISO RGD:731748 6480464 Genistein results in increased expression of JAK2 mRNA CTD PMID:26865667 , PMID:26865669 Ginkgoic acid decreases phosphorylation ISO RGD:731748 127284886 Ginkgoic acid decreases phosphorylation of JAK2 protein in stomach RGD glucose multiple interactions ISO RGD:731748 6480464 (3 more ... CTD PMID:15677497 glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of JAK2 protein CTD PMID:20060012 glucose multiple interactions EXP 6480464 alpha-cyano-(3, 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein] CTD PMID:20060012 glutathione multiple interactions ISO RGD:10823 6480464 Glutathione inhibits the reaction [15-deoxy-delta(12 more ... CTD PMID:12847270 Goe 6976 multiple interactions EXP 6480464 Go 6976 results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 Goe 6976 multiple interactions ISO RGD:10823 6480464 Go 6976 results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 gold atom multiple interactions ISO RGD:731748 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 gold(0) multiple interactions ISO RGD:731748 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 hesperetin multiple interactions EXP 6480464 hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33522063 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of JAK2 mRNA] CTD PMID:34748272 hexadecanoic acid multiple interactions ISO RGD:731748 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA CTD PMID:30547786 hexestrol increases expression ISO RGD:731748 6480464 Hexestrol results in increased expression of JAK2 mRNA CTD PMID:26865669 hispidulin decreases phosphorylation ISO RGD:731748 149735333 hispidulin decreases phoshphorylation of JAK2 protein in colon and colorectum RGD hydrogen peroxide multiple interactions ISO RGD:10823 6480464 Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:12847270 hydrogen peroxide decreases expression ISO RGD:731748 6480464 Hydrogen Peroxide results in decreased expression of JAK2 mRNA CTD PMID:34581912 hydrogen peroxide decreases phosphorylation ISO RGD:731748 6480464 Hydrogen Peroxide results in decreased phosphorylation of JAK2 protein CTD PMID:19635391 ivermectin decreases expression ISO RGD:731748 6480464 Ivermectin results in decreased expression of JAK2 protein CTD PMID:34904774 ivermectin multiple interactions ISO RGD:731748 6480464 AZD 1480 inhibits the reaction [SLC2A4 protein inhibits the reaction [Ivermectin results in decreased expression of JAK2 protein]], SLC2A4 protein inhibits the reaction [Ivermectin results in decreased expression of JAK2 protein] CTD PMID:34904774 kainic acid multiple interactions ISO RGD:731748 6480464 EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein], EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]] CTD PMID:18711747 kainic acid decreases expression EXP 6480464 Kainic Acid results in decreased expression of JAK2 protein CTD PMID:18711747 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of JAK2 mRNA CTD PMID:20080153 L-arginine increases expression ISO RGD:10823 6480464 Arginine results in increased expression of JAK2 protein CTD PMID:34423886 L-arginine multiple interactions ISO RGD:10823 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased expression of JAK2 protein]] more ... CTD PMID:34423886 lapatinib multiple interactions ISO RGD:731748 6480464 Lapatinib inhibits the reaction [sodium arsenite results in increased phosphorylation of JAK2 protein] CTD PMID:32890875 limonin multiple interactions ISO RGD:10823 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased expression of JAK2 protein]] more ... CTD PMID:34423886 linagliptin multiple interactions ISO RGD:10823 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of JAK2 protein modified form] CTD PMID:29864483 linagliptin multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:35122774 lipopolysaccharide increases activity ISO RGD:10823 6480464 [Lipopolysaccharides results in increased activity of JAK2 protein] which results in increased activity of STAT3 protein, Lipopolysaccharides results in increased activity of JAK2 protein CTD PMID:24486434 lipopolysaccharide multiple interactions ISO RGD:10823 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein], kaempferol 7-O-glucoside inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] CTD PMID:29470957 , PMID:30053449 lipopolysaccharide increases phosphorylation ISO RGD:10823 6480464 Lipopolysaccharides results in increased phosphorylation of JAK2 protein CTD PMID:25576658 more ... losartan multiple interactions ISO RGD:731748 127285667 losartan inhibits the reaction [Angiotensin II increases phosphorylation of JAK2 protein in liver] RGD LY294002 multiple interactions ISO RGD:10823 149735351 LY294002 inhibits the reaction [cisplatin increases phosphorylation of Jak2 protein in kidney] RGD melittin decreases phosphorylation ISO RGD:731748 6480464 Melitten results in decreased phosphorylation of JAK2 protein CTD PMID:22027265 melphalan decreases expression ISO RGD:731748 6480464 Melphalan results in decreased expression of JAK2 mRNA CTD PMID:22363485 mercury atom affects expression ISO RGD:731748 6480464 Mercury affects the expression of JAK2 mRNA CTD PMID:23920476 mercury dichloride decreases phosphorylation ISO RGD:731748 6480464 Mercuric Chloride results in decreased phosphorylation of JAK2 protein CTD PMID:16896058 , PMID:19635391 mercury(0) affects expression ISO RGD:731748 6480464 Mercury affects the expression of JAK2 mRNA CTD PMID:23920476 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:35122774 mestranol increases expression ISO RGD:731748 6480464 Mestranol results in increased expression of JAK2 mRNA CTD PMID:26865669 methyl methanesulfonate increases expression ISO RGD:731748 6480464 Methyl Methanesulfonate results in increased expression of JAK2 mRNA CTD PMID:23649840 methylmercury chloride affects phosphorylation ISO RGD:10823 6480464 methylmercuric chloride affects the phosphorylation of JAK2 protein CTD PMID:33338554 Methylthiouracil multiple interactions ISO RGD:731748 6480464 Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:26298005 mitoxantrone decreases expression ISO RGD:731748 6480464 Mitoxantrone results in decreased expression of JAK2 mRNA CTD PMID:26537877 , PMID:28940058 N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions EXP 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of JAK2 protein] CTD PMID:31231976 N-acetyl-L-cysteine multiple interactions ISO RGD:731748 127284846 N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of JAK2 protein in the stomach) RGD N-acetyl-L-cysteine multiple interactions ISO RGD:731748 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein], Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] CTD PMID:29894800 , PMID:34627931 N-acetyl-L-cysteine multiple interactions ISO RGD:731748 127284886 N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid decreases phosphorylation of JAK2 protein in stomach] RGD N-acetyl-L-cysteine multiple interactions ISO RGD:731748 149735333 N-acetyl-L-cysteine inhibits the reaction [hispidulin decreases phoshphorylation of JAK2 protein in colon and colorectum] RGD N-acetyl-L-cysteine multiple interactions ISO RGD:10823 6480464 Acetylcysteine inhibits the reaction [15-deoxy-delta(12 more ... CTD PMID:12847270 N-nitrosodiethylamine increases phosphorylation ISO RGD:10823 127285675 N-nitrosodiethylamine increases phosphorylation of JAK2 protein in liver RGD N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of JAK2 protein CTD PMID:29698782 N-nitrosodiethylamine decreases response to substance ISO RGD:10823 6480464 JAK2 gene mutant form results in decreased susceptibility to Diethylnitrosamine CTD PMID:28100771 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of JAK2 mRNA CTD PMID:25380136 nickel atom multiple interactions ISO RGD:731748 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of JAK2 mRNA] CTD PMID:14575637 nickel atom increases expression ISO RGD:731748 6480464 Nickel results in increased expression of JAK2 mRNA CTD PMID:24768652 , PMID:25583101 nickel atom decreases expression ISO RGD:731748 6480464 Nickel results in decreased expression of JAK2 mRNA CTD PMID:23195993 nickel atom affects expression ISO RGD:731748 6480464 Nickel affects the expression of JAK2 mRNA CTD PMID:14575637 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of JAK2 mRNA CTD PMID:22546817 nicotine increases response to substance ISO RGD:731748 6480464 JAK2 results in increased susceptibility to Nicotine CTD PMID:20943775 nicotine multiple interactions EXP 6480464 Bungarotoxins inhibits the reaction [Nicotine results in increased phosphorylation of JAK2 protein] CTD PMID:34153408 nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of JAK2 protein CTD PMID:34153408 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of JAK2 mRNA CTD PMID:29155039 nimesulide decreases phosphorylation ISO RGD:731748 127285656 Nimesulide decreases phoshphorylation of JAK2 in esophagus squamous epithelium RGD nitric oxide multiple interactions ISO RGD:10823 6480464 JAK2 protein promotes the reaction [IFNG protein results in increased abundance of Nitric Oxide] CTD PMID:12847270 nitric oxide decreases expression ISO RGD:10823 6480464 Nitric Oxide deficiency results in decreased expression of JAK2 mRNA CTD PMID:15878706 okadaic acid multiple interactions ISO RGD:731748 6480464 JAK2 protein affects the reaction [[PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in decreased susceptibility to Okadaic Acid] CTD PMID:21715663 olanzapine multiple interactions EXP 6480464 [[olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein more ... CTD PMID:18976543 , PMID:19304867 olanzapine increases activity EXP 6480464 olanzapine results in increased activity of JAK2 protein CTD PMID:19304867 oleic acid multiple interactions ISO RGD:731748 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA CTD PMID:30547786 ozone multiple interactions ISO RGD:10823 6480464 Ozone results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:26949510 pantoprazole multiple interactions ISO RGD:10823 127285673 pantoprazole decreases expression of JAK2 mRNA and decreases phosphorylation of JAK2 protein in gastrocnemius RGD paracetamol affects expression ISO RGD:10823 6480464 Acetaminophen affects the expression of JAK2 mRNA CTD PMID:17562736 paroxetine increases expression ISO RGD:731748 6480464 Paroxetine results in increased expression of JAK2 mRNA CTD PMID:32020710 paroxetine multiple interactions ISO RGD:731748 6480464 LY 215840 promotes the reaction [Paroxetine results in increased expression of JAK2 mRNA] CTD PMID:32020710 PD123319 multiple interactions ISO RGD:731748 127285667 PD123319 co-treated with losartan inhibits the reaction [Angiotensin II increases phosphorylation of JAK2 protein in liver] RGD perfluorooctane-1-sulfonic acid decreases expression ISO RGD:731748 6480464 perfluorooctane sulfonic acid results in decreased expression of JAK2 mRNA CTD PMID:27153767 phenylpropanolamine increases expression EXP 6480464 Phenylpropanolamine results in increased expression of JAK2 mRNA, Phenylpropanolamine results in increased expression of JAK2 protein CTD PMID:24792324 PhIP increases expression ISO RGD:731748 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of JAK2 mRNA CTD PMID:29362861 phosphane decreases expression EXP 6480464 phosphine results in decreased expression of JAK2 mRNA CTD PMID:34427094 phosphatidic acid increases phosphorylation ISO RGD:10823 6480464 Phosphatidic Acids results in increased phosphorylation of JAK2 protein CTD PMID:16354768 pipoxolan multiple interactions ISO RGD:10823 6480464 pipoxolan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:32677756 pirinixic acid increases expression ISO RGD:10823 6480464 pirinixic acid results in increased expression of JAK2 mRNA CTD PMID:18445702 platycodin D decreases phosphorylation ISO RGD:731748 6480464 platycodin D results in decreased phosphorylation of JAK2 protein CTD PMID:25250884 ponatinib decreases activity ISO RGD:731748 6480464 ponatinib results in decreased activity of JAK2 protein CTD PMID:19878872 Ponicidin decreases phosphorylation ISO RGD:731748 127285620 Ponicidin decreases phosphorylation of JAK2 protein in the stomach RGD potassium chromate decreases expression ISO RGD:731748 6480464 potassium chromate(VI) results in decreased expression of JAK2 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:731748 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of JAK2 mRNA CTD PMID:22079256 progesterone increases expression ISO RGD:731748 6480464 Progesterone results in increased expression of JAK2 mRNA CTD PMID:20864642 propofol decreases phosphorylation ISO RGD:731748 125097524 Propofol decreases phosphorylation of JAK2 protein in colon epithelium RGD pterostilbene decreases phosphorylation ISO RGD:731748 6480464 pterostilbene results in decreased phosphorylation of JAK2 protein CTD PMID:23313376 quercetin decreases expression EXP 6480464 Quercetin analog results in decreased expression of JAK2 protein CTD PMID:23907460 quercetin multiple interactions ISO RGD:731748 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 quercetin decreases phosphorylation ISO RGD:731748 6480464 Quercetin results in decreased phosphorylation of JAK2 protein CTD PMID:24275163 quercetin increases expression ISO RGD:731748 6480464 Quercetin results in increased expression of JAK2 mRNA CTD PMID:21632981 quercetin decreases phosphorylation ISO RGD:10823 6480464 Quercetin results in decreased phosphorylation of JAK2 protein CTD PMID:24275163 quercetin increases phosphorylation EXP 6480464 Quercetin analog results in increased phosphorylation of JAK2 protein CTD PMID:23907460 quercetin multiple interactions EXP 6480464 alpha-cyano-(3 more ... CTD PMID:22426011 , PMID:23907460 quercetin 3-O-beta-D-glucofuranoside increases expression ISO RGD:731748 6480464 isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 quercetin 3-O-beta-D-glucopyranoside increases expression ISO RGD:731748 6480464 isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 rac-lactic acid decreases expression ISO RGD:731748 6480464 Lactic Acid results in decreased expression of JAK2 mRNA CTD PMID:30851411 raloxifene multiple interactions ISO RGD:731748 6480464 Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] CTD PMID:17272397 raloxifene decreases expression ISO RGD:731748 6480464 Raloxifene Hydrochloride results in decreased expression of JAK2 mRNA CTD PMID:26865669 reactive oxygen species increases activity ISO RGD:731748 6480464 Reactive Oxygen Species results in increased activity of JAK2 protein CTD PMID:20523355 resveratrol decreases phosphorylation ISO RGD:731748 6480464 resveratrol results in decreased phosphorylation of JAK2 protein CTD PMID:23372833 more ... resveratrol multiple interactions ISO RGD:731748 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of JAK2 mRNA CTD PMID:23557933 resveratrol multiple interactions ISO RGD:10823 6480464 [Resveratrol co-treated with alpha-cyano-(3 more ... CTD PMID:31881177 , PMID:34423886 Rhynchophylline multiple interactions EXP 6480464 rhyncophylline inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of JAK2 protein] CTD PMID:31231976 rotenone multiple interactions ISO RGD:731748 6480464 Rotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of JAK2 protein], Rotenone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 , PMID:15748169 rotenone decreases phosphorylation ISO RGD:731748 6480464 Rotenone results in decreased phosphorylation of JAK2 protein CTD PMID:19635391 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] CTD PMID:22426011 ruxolitinib decreases activity ISO RGD:731748 6480464 ruxolitinib results in decreased activity of JAK2 protein CTD PMID:24883332 , PMID:26300391 ruxolitinib affects response to substance ISO RGD:731748 6480464 JAK2 gene mutant form affects the susceptibility to ruxolitinib CTD PMID:26300391 ruxolitinib multiple interactions ISO RGD:731748 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein CTD PMID:30012499 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression ISO RGD:10823 6480464 Buthionine Sulfoximine results in decreased expression of JAK2 mRNA CTD PMID:15878706 S3I-201 multiple interactions ISO RGD:731748 149735343 S3I-201 inhibits the reaction [Rapamycin increases phosphorylation of JAK2 protein in lung epithelium] RGD Salinomycin multiple interactions ISO RGD:731748 6480464 salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK2 protein] CTD PMID:32822738 selumetinib increases phosphorylation ISO RGD:731748 127285668 selumetinib increases phosphorylation of JAK2 protein in colonic epithelium RGD silibinin multiple interactions ISO RGD:731748 149735360 silibinin decreases expression and phosphorylation of JAK2 protein in breast epithelium RGD silicon dioxide decreases expression ISO RGD:731748 6480464 Silicon Dioxide results in decreased expression of JAK2 mRNA CTD PMID:25351596 silicon dioxide increases phosphorylation ISO RGD:731748 6480464 Silicon Dioxide results in increased phosphorylation of JAK2 protein CTD PMID:29894800 silicon dioxide multiple interactions ISO RGD:731748 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein] more ... CTD PMID:29894800 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]] more ... CTD PMID:16534557 more ... simvastatin decreases phosphorylation EXP 6480464 Simvastatin results in decreased phosphorylation of JAK2 protein CTD PMID:18400235 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of JAK2 mRNA CTD PMID:16414398 Sinomenine decreases phosphorylation EXP 149735350 Sinomenine decreases phosphorylation of Jak2 protein in lumber vertebra RGD sodium arsenite multiple interactions ISO RGD:731748 6480464 Lapatinib inhibits the reaction [sodium arsenite results in increased phosphorylation of JAK2 protein] more ... CTD PMID:15116095 more ... sodium arsenite increases phosphorylation ISO RGD:731748 6480464 sodium arsenite results in increased phosphorylation of JAK2 protein CTD PMID:32890875 sodium arsenite increases expression ISO RGD:731748 6480464 sodium arsenite results in increased expression of JAK2 mRNA CTD PMID:28444938 sphingosine 1-phosphate increases phosphorylation ISO RGD:731748 6480464 sphingosine 1-phosphate results in increased phosphorylation of JAK2 protein CTD PMID:32401414 spironolactone multiple interactions EXP 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 stattic multiple interactions ISO RGD:10823 6480464 stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA], stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] CTD PMID:22454431 streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein, dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein] CTD PMID:34391751 succimer multiple interactions ISO RGD:10823 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of JAK2 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of JAK2 mRNA CTD PMID:21641980 , PMID:26378955 sulfasalazine multiple interactions ISO RGD:10823 6480464 Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein] CTD PMID:32272095 sulforaphane multiple interactions ISO RGD:10823 6480464 sulforaphane inhibits the reaction [Cyclosporine results in increased phosphorylation of JAK2 protein] CTD PMID:23958496 sunitinib decreases expression ISO RGD:731748 6480464 Sunitinib results in decreased expression of JAK2 mRNA CTD PMID:31533062 T-2 toxin increases expression ISO RGD:10823 6480464 T-2 Toxin results in increased expression of JAK2 mRNA CTD PMID:22454431 T-2 toxin decreases expression ISO RGD:731748 6480464 T-2 Toxin results in decreased expression of JAK2 mRNA CTD PMID:34581912 T-2 toxin multiple interactions ISO RGD:10823 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 tacrolimus hydrate increases phosphorylation ISO RGD:10823 6480464 Tacrolimus results in increased phosphorylation of JAK2 protein CTD PMID:23958496 tert-butyl hydroperoxide multiple interactions ISO RGD:731748 6480464 3, 4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of JAK2 protein] CTD PMID:29128606 tert-butyl hydroperoxide decreases phosphorylation ISO RGD:731748 6480464 tert-Butylhydroperoxide results in decreased phosphorylation of JAK2 protein CTD PMID:29128606 testosterone enanthate increases expression EXP 6480464 testosterone enanthate results in increased expression of JAK2 mRNA CTD PMID:25603467 tetrachloromethane affects expression ISO RGD:10823 6480464 Carbon Tetrachloride affects the expression of JAK2 mRNA CTD PMID:17484886 tetrachloromethane increases phosphorylation ISO RGD:10823 6480464 Carbon Tetrachloride results in increased phosphorylation of JAK2 protein CTD PMID:34029542 tetrachloromethane multiple interactions ISO RGD:10823 6480464 ganoderic acid A inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK2 protein] CTD PMID:34029542 theobromine multiple interactions EXP 127229954 [Theobromine co-treated with Theanine] inhibits the reaction [1 more ... RGD thymoquinone multiple interactions ISO RGD:731748 6480464 Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] CTD PMID:34627931 thymoquinone multiple interactions ISO RGD:10823 6480464 Doxorubicin promotes the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein], thymoquinone inhibits the reaction [Doxorubicin results in increased phosphorylation of JAK2 protein] CTD PMID:34605108 thymoquinone decreases phosphorylation ISO RGD:731748 6480464 thymoquinone results in decreased phosphorylation of JAK2 protein CTD PMID:34627931 thymoquinone decreases phosphorylation ISO RGD:10823 6480464 thymoquinone results in decreased phosphorylation of JAK2 protein CTD PMID:34605108 Tiron multiple interactions ISO RGD:731748 6480464 1 more ... CTD PMID:15677497 tofacitinib decreases activity ISO RGD:731748 6480464 tofacitinib results in decreased activity of JAK2 protein CTD PMID:26300391 tofacitinib multiple interactions ISO RGD:731748 6480464 tofacitinib inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein] more ... CTD PMID:21548952 more ... tofacitinib affects response to substance ISO RGD:731748 6480464 JAK2 gene mutant form affects the susceptibility to tofacitinib CTD PMID:26300391 trichostatin A multiple interactions ISO RGD:731748 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of JAK2 mRNA] CTD PMID:14575637 triptonide decreases expression ISO RGD:10823 6480464 triptonide results in decreased expression of JAK2 mRNA CTD PMID:33045310 tyrphostin B42 multiple interactions ISO RGD:10823 149735351 tyrphostin B42 inhibits the reaction [cisplatin increases expression of Jak2 mRNA in kidney] RGD tyrphostin B42 multiple interactions ISO RGD:731748 127284886 tyrphostin B42 co-treated with N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases phosphorylation of JAK2 protein in stomach] RGD tyrphostin B42 decreases expression EXP 18337263 Turphostin B42 decreased expression of Jak2 mRNA in myofibroblasts RGD tyrphostin B42 multiple interactions ISO RGD:731748 127285668 tyrphostin B42 inhibits the reaction [selumetinib increases phosphorylation of JAK2 protein in colonic epithelium] RGD tyrphostin B42 multiple interactions ISO RGD:731748 127285665 tyrphostin B42 decreases expression and phosphorylation of JAK2 protein in colonic epithelium RGD urethane multiple interactions ISO RGD:10823 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of JAK2 mRNA CTD PMID:12400877 urethane increases expression ISO RGD:731748 6480464 Urethane results in increased expression of JAK2 mRNA CTD PMID:28818685 urethane increases expression ISO RGD:10823 6480464 Urethane results in increased expression of JAK2 mRNA CTD PMID:12400877 valproic acid increases methylation ISO RGD:731748 6480464 Valproic Acid results in increased methylation of JAK2 gene CTD PMID:29154799 valproic acid decreases expression ISO RGD:731748 6480464 Valproic Acid results in decreased expression of JAK2 mRNA CTD PMID:25716160 valproic acid increases expression ISO RGD:731748 6480464 Valproic Acid results in increased expression of JAK2 mRNA CTD PMID:29154799 valsartan multiple interactions ISO RGD:731748 6480464 Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 verteporfin decreases expression ISO RGD:10823 6480464 Verteporfin results in decreased expression of JAK2 protein CTD PMID:31812773 verteporfin multiple interactions ISO RGD:10823 6480464 [Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of JAK2 protein CTD PMID:31812773 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of JAK2 mRNA CTD PMID:23555832 zidovudine multiple interactions ISO RGD:731748 6480464 [Zidovudine co-treated with IFNA1 protein] results in increased expression of JAK2 mRNA CTD PMID:20370541 zoledronic acid increases expression ISO RGD:731748 6480464 zoledronic acid results in increased expression of JAK2 mRNA CTD PMID:24714768
