JAK2 (Janus kinase 2) - Rat Genome Database

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Gene: JAK2 (Janus kinase 2) Sus scrofa
Analyze
Symbol: JAK2
Name: Janus kinase 2
RGD ID: 14229098
Description: ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); growth hormone receptor binding (ortholog); heme binding (ortholog); INVOLVED IN axon regeneration (ortholog); cell differentiation (ortholog); cell surface receptor signaling pathway via JAK-STAT (ortholog); PARTICIPATES IN aldosterone signaling pathway; altered Jak-Stat signaling pathway; angiotensin II signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); acute myeloid leukemia (ortholog); FOUND IN euchromatin (ortholog); extrinsic component of cytoplasmic side of plasma membrane (ortholog); extrinsic component of plasma membrane (ortholog); INTERACTS WITH 5-aza-2'-deoxycytidine; deoxynivalenol; ochratoxin A
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: JAK-2; tyrosine-protein kinase JAK2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,848,689 - 217,002,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,849,744 - 217,002,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,696,921 - 242,837,407 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute Lymphoblastic Leukemia, with Lymphomatous Features  (ISO)
acute myeloid leukemia  (ISO)
adrenocortical carcinoma  (ISO)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (ISO)
anemia  (ISO)
ankylosing spondylitis  (ISO)
atherosclerosis  (ISO)
bacterial gastritis  (ISO)
Brain Injuries  (ISO)
Budd-Chiari syndrome  (ISO)
Cachexia  (ISO)
calcinosis  (ISO)
Cancer Pain  (ISO)
chromosome 9p deletion syndrome  (ISO)
chronic myelogenous leukemia, BCR-ABL1 positive  (ISO)
chronic myeloid leukemia  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (ISO)
colorectal carcinoma  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
Diabetic Nephropathies  (ISO)
esophageal carcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
essential thrombocythemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Colitis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
familial erythrocytosis 1  (ISO)
familial erythrocytosis 2  (ISO)
genetic disease  (ISO)
Genetic Predisposition to Disease  (ISO)
glucose intolerance  (ISO)
Growth Disorders  (ISO)
heart disease  (ISO)
heart valve disease  (ISO)
hepatocellular carcinoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hyperalgesia  (ISO)
hyperuricemia  (ISO)
Inflammation  (ISO)
Intestinal Reperfusion Injury  (ISO)
leukemia  (ISO)
limited scleroderma  (ISO)
liver cancer  (ISO)
liver cirrhosis  (ISO)
Liver Injury  (ISO)
Liver Reperfusion Injury  (ISO)
lung adenocarcinoma  (ISO)
lung carcinoma  (ISO)
lung non-small cell carcinoma  (ISO)
mesenteric vascular occlusion  (ISO)
metabolic dysfunction-associated steatohepatitis  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
myelofibrosis  (ISO)
myeloid neoplasm  (ISO)
myeloproliferative neoplasm  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
nasopharynx carcinoma  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephrotic syndrome  (ISO)
Niemann-Pick disease type C1  (ISO)
obesity  (ISO)
polycythemia  (ISO)
polycythemia vera  (ISO)
portal hypertension  (ISO)
Pregnancy Complications  (ISO)
primary biliary cholangitis  (ISO)
primary ovarian insufficiency  (ISO)
Prostatic Neoplasms  (ISO)
Reperfusion Injury  (ISO)
retinal detachment  (ISO)
rheumatoid arthritis  (ISO)
scrapie  (ISO)
Sepsis  (ISO)
Sepsis-Associated Encephalopathy  (ISO)
Spinal Cord Injuries  (ISO)
Splenomegaly  (ISO)
Spontaneous Abortions  (ISO)
steatotic liver disease  (ISO)
stomach cancer  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (ISO)
Thrombocythemia 3  (ISO)
thrombocytosis  (ISO)
Thromboembolism  (ISO)
thrombosis  (ISO)
transient cerebral ischemia  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
Venous Thrombosis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (IEA)
axon regeneration  (ISO)
cell differentiation  (IEA,ISO)
cell surface receptor signaling pathway via JAK-STAT  (IBA,IEA,ISO)
cellular response to dexamethasone stimulus  (IEA,ISO)
cellular response to interleukin-3  (IEA,ISO)
cellular response to lipopolysaccharide  (IEA,ISO)
chromatin organization  (IEA)
chromatin remodeling  (IEA)
collagen-activated signaling pathway  (IEA)
cytokine-mediated signaling pathway  (IBA,IEA,ISS)
enzyme-linked receptor protein signaling pathway  (IEA,ISO)
erythrocyte differentiation  (IBA,IEA,ISS)
extrinsic apoptotic signaling pathway  (IEA,ISO)
G protein-coupled receptor signaling pathway  (ISO)
granulocyte-macrophage colony-stimulating factor signaling pathway  (IEA)
growth hormone receptor signaling pathway  (IEA)
growth hormone receptor signaling pathway via JAK-STAT  (IBA,IEA,ISO,ISS)
hormone-mediated signaling pathway  (ISO)
immune system process  (IEA)
innate immune response  (IEA)
interleukin-12-mediated signaling pathway  (IEA)
interleukin-3-mediated signaling pathway  (IEA)
interleukin-5-mediated signaling pathway  (IEA)
intracellular signal transduction  (IBA,IEA,ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (ISO)
mammary gland epithelium development  (IEA,ISO)
microglial cell activation  (IEA)
mineralocorticoid receptor signaling pathway  (ISO)
modulation of chemical synaptic transmission  (ISO)
myeloid cell differentiation  (IEA,ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of cell-cell adhesion  (ISO)
negative regulation of neuron apoptotic process  (ISO)
platelet-derived growth factor receptor signaling pathway  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of apoptotic signaling pathway  (IEA,ISO)
positive regulation of cell activation  (ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cell-substrate adhesion  (IEA)
positive regulation of cold-induced thermogenesis  (IEA)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of DNA binding  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of epithelial cell apoptotic process  (ISO)
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation  (ISO)
positive regulation of growth hormone receptor signaling pathway  (IEA)
positive regulation of insulin secretion  (ISO)
positive regulation of interleukin-1 beta production  (IEA,ISO)
positive regulation of leukocyte proliferation  (IEA)
positive regulation of MAPK cascade  (ISO)
positive regulation of MHC class II biosynthetic process  (IEA)
positive regulation of natural killer cell proliferation  (IEA)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase biosynthetic process  (IEA)
positive regulation of NK T cell proliferation  (IEA)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA)
positive regulation of phosphoprotein phosphatase activity  (ISO)
positive regulation of platelet activation  (IEA,ISO)
positive regulation of platelet aggregation  (IEA,ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (IEA)
positive regulation of SMAD protein signal transduction  (IEA,ISO)
positive regulation of T cell proliferation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of tumor necrosis factor production  (IEA)
positive regulation of type II interferon production  (IEA)
positive regulation of tyrosine phosphorylation of STAT protein  (IEA,ISS)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
post-embryonic hemopoiesis  (IEA)
post-translational protein modification  (IEA,ISS)
protein autophosphorylation  (ISO)
regulation of apoptotic process  (IBA,IEA)
regulation of inflammatory response  (IEA)
regulation of nitric oxide biosynthetic process  (ISO)
regulation of postsynapse to nucleus signaling pathway  (ISO)
response to amine  (ISO)
response to antibiotic  (IEA,ISO)
response to hydroperoxide  (ISO)
response to interleukin-12  (IEA)
response to lipopolysaccharide  (IEA)
response to organic cyclic compound  (ISO)
response to oxidative stress  (ISO)
response to tumor necrosis factor  (IEA)
signal transduction  (IEA,ISS)
symbiont-induced defense-related programmed cell death  (IEA,ISO)
transcription by RNA polymerase II  (IEA,ISO)
tumor necrosis factor-mediated signaling pathway  (IEA)
type II interferon-mediated signaling pathway  (ISO)
tyrosine phosphorylation of STAT protein  (ISO)

References
Additional References at PubMed
PMID:17510232   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
JAK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,848,689 - 217,002,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,849,744 - 217,002,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,696,921 - 242,837,407 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JAK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3894,984,390 - 5,129,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl94,984,390 - 5,129,948 (+)EnsemblGRCh38hg38GRCh38
GRCh3794,984,390 - 5,129,948 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3694,975,245 - 5,117,995 (+)NCBINCBI36Build 36hg18NCBI36
Build 3494,975,244 - 5,117,995NCBI
Celera94,910,860 - 5,053,802 (+)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef94,940,783 - 5,083,727 (+)NCBIHuRef
CHM1_194,985,470 - 5,128,355 (+)NCBICHM1_1
T2T-CHM13v2.094,989,498 - 5,135,022 (+)NCBIT2T-CHM13v2.0
Jak2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,229,006 - 29,290,495 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,229,228 - 29,290,480 (+)EnsemblGRCm39 Ensembl
GRCm381929,251,803 - 29,313,095 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,251,828 - 29,313,080 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,326,318 - 29,387,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361929,318,452 - 29,377,979 (+)NCBIMGSCv36mm8
Celera1930,028,576 - 30,089,642 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1923.73NCBI
Jak2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,408,905 - 236,468,769 (+)NCBIGRCr8
mRatBN7.21226,995,334 - 227,054,381 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,995,334 - 227,054,189 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,396,988 - 235,455,863 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,326,646 - 242,385,527 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,144,413 - 235,203,184 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,398,667 - 247,457,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,398,598 - 247,458,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,646,160 - 254,706,478 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,915,995 - 232,974,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,080,017 - 233,138,786 (+)NCBI
Celera1224,147,256 - 224,206,104 (+)NCBICelera
Cytogenetic Map1q52NCBI
Jak2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554349,227,595 - 9,341,208 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554349,227,897 - 9,341,208 (+)NCBIChiLan1.0ChiLan1.0
JAK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211119,420,003 - 119,589,890 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19119,425,950 - 119,595,837 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v094,820,303 - 4,971,867 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.195,006,271 - 5,156,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl95,006,271 - 5,156,626 (+)Ensemblpanpan1.1panPan2
JAK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,321,055 - 93,438,898 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,142,635 - 93,435,997 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha193,730,062 - 93,844,204 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0193,940,875 - 93,989,640 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,877,224 - 93,990,814 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,507,891 - 93,622,032 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,232,417 - 93,346,624 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,996,654 - 94,110,963 (+)NCBIUU_Cfam_GSD_1.0
Jak2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947140,931,052 - 141,061,286 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936503110,963 - 241,867 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936503111,722 - 243,627 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11274,421,243 - 74,566,766 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1274,421,016 - 74,566,710 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603862,818,134 - 62,927,470 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jak2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247369,724,369 - 9,830,365 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247369,724,876 - 9,827,364 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in JAK2
4010 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 7 2 1 3
Low 2 2 16 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_214113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021082799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021082802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021082806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021082809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB006011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB036336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB036337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEMK02000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK397466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY509893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU694859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU861563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU928554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ322254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01025073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSSSCT00000005748   ⟹   ENSSSCP00000005606
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1216,860,648 - 217,002,137 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000034494   ⟹   ENSSSCP00000029110
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1216,871,081 - 217,001,917 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000034678   ⟹   ENSSSCP00000029236
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1216,848,689 - 217,001,948 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000071201   ⟹   ENSSSCP00000062892
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1216,877,713 - 217,002,148 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000075275   ⟹   ENSSSCP00000072050
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1216,849,716 - 216,933,657 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000086181   ⟹   ENSSSCP00000061060
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1216,851,378 - 217,002,137 (-)Ensembl
RefSeq Acc Id: NM_214113   ⟹   NP_999278
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11216,850,282 - 217,001,828 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082799   ⟹   XP_020938458
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11216,849,744 - 217,002,310 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082802   ⟹   XP_020938461
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11216,849,744 - 217,002,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082806   ⟹   XP_020938465
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11216,849,744 - 216,959,331 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021082809   ⟹   XP_020938468
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11216,849,744 - 217,002,127 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020938458   ⟸   XM_021082799
- Peptide Label: isoform X1
- UniProtKB: O19064 (UniProtKB/Swiss-Prot),   A0A8D1N1K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938461   ⟸   XM_021082802
- Peptide Label: isoform X1
- UniProtKB: O19064 (UniProtKB/Swiss-Prot),   A0A8D1N1K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020938468   ⟸   XM_021082809
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020938465   ⟸   XM_021082806
- Peptide Label: isoform X1
- UniProtKB: O19064 (UniProtKB/Swiss-Prot),   A0A8D1N1K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_999278   ⟸   NM_214113
- UniProtKB: O19064 (UniProtKB/Swiss-Prot),   A0A8D1N1K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000005606   ⟸   ENSSSCT00000005748
RefSeq Acc Id: ENSSSCP00000029110   ⟸   ENSSSCT00000034494
RefSeq Acc Id: ENSSSCP00000029236   ⟸   ENSSSCT00000034678
RefSeq Acc Id: ENSSSCP00000072050   ⟸   ENSSSCT00000075275
RefSeq Acc Id: ENSSSCP00000061060   ⟸   ENSSSCT00000086181
RefSeq Acc Id: ENSSSCP00000062892   ⟸   ENSSSCT00000071201
Protein Domains
FERM   Protein kinase   SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005215 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00005029324 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015063581 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025037142 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00030052311 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00035019132 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00040006566 UniProtKB/TrEMBL
  ENSSSCG00045032577 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00050056822 UniProtKB/TrEMBL
  ENSSSCG00055018283 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00060064055 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00065071184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00070029405 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005748.5 UniProtKB/TrEMBL
  ENSSSCT00000034494.4 UniProtKB/TrEMBL
  ENSSSCT00000034678 ENTREZGENE
  ENSSSCT00000034678.4 UniProtKB/Swiss-Prot
  ENSSSCT00000071201.1 UniProtKB/TrEMBL
  ENSSSCT00000086181 ENTREZGENE
  ENSSSCT00000086181.2 UniProtKB/TrEMBL
  ENSSSCT00005047950.1 UniProtKB/Swiss-Prot
  ENSSSCT00005047972.1 UniProtKB/TrEMBL
  ENSSSCT00005047985.1 UniProtKB/Swiss-Prot
  ENSSSCT00005047994.1 UniProtKB/Swiss-Prot
  ENSSSCT00015085604.1 UniProtKB/Swiss-Prot
  ENSSSCT00015085750.1 UniProtKB/TrEMBL
  ENSSSCT00025050590.1 UniProtKB/Swiss-Prot
  ENSSSCT00025050594.1 UniProtKB/TrEMBL
  ENSSSCT00030072992.1 UniProtKB/Swiss-Prot
  ENSSSCT00030073030.1 UniProtKB/TrEMBL
  ENSSSCT00035024766.1 UniProtKB/Swiss-Prot
  ENSSSCT00035024782.1 UniProtKB/TrEMBL
  ENSSSCT00040008668.1 UniProtKB/TrEMBL
  ENSSSCT00045055979.1 UniProtKB/Swiss-Prot
  ENSSSCT00045056279.1 UniProtKB/TrEMBL
  ENSSSCT00050077468.1 UniProtKB/TrEMBL
  ENSSSCT00055036075.1 UniProtKB/Swiss-Prot
  ENSSSCT00055036232.1 UniProtKB/TrEMBL
  ENSSSCT00060087675.1 UniProtKB/Swiss-Prot
  ENSSSCT00060087722.1 UniProtKB/TrEMBL
  ENSSSCT00065098044.1 UniProtKB/Swiss-Prot
  ENSSSCT00065098059.1 UniProtKB/TrEMBL
  ENSSSCT00070059075.1 UniProtKB/TrEMBL
  ENSSSCT00070059080.1 UniProtKB/TrEMBL
  ENSSSCT00070059083.1 UniProtKB/Swiss-Prot
  ENSSSCT00070059086.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_F1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_F2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Jak1_PHL_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JAK2_FERM_C-lobe UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JAK2_SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTK_Jak2_rpt1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTKc_Jak2_rpt2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_non-rcpt_Jak/Tyk2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_non-rcpt_Jak2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397201 UniProtKB/Swiss-Prot
NCBI Gene JAK2 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE HOPSCOTCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE JAK2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FERM_F1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_F2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Jak1_Phl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF TyrPK_Jak UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS JANUSKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JANUSKINASE2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART B41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1W734_PIG UniProtKB/TrEMBL
  A0A5G2QGG0_PIG UniProtKB/TrEMBL
  A0A8D1N1K4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WE37_PIG UniProtKB/TrEMBL
  A0A900R1X7_PIG UniProtKB/TrEMBL
  J9JIK9_PIG UniProtKB/TrEMBL
  JAK2_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q15I69_PIG UniProtKB/TrEMBL
  Q6JDV5_PIG UniProtKB/TrEMBL
  Q9TTI9_PIG UniProtKB/TrEMBL
  Q9TTJ0_PIG UniProtKB/TrEMBL
UniProt Secondary A0A4X1W738 UniProtKB/TrEMBL
  K7GML7 UniProtKB/TrEMBL
VGNC ID VGNC:89271 ENTREZGENE