Bw97 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw97 (Body weight QTL 97) Rattus norvegicus

Symbol: Bw97
Name: Body weight QTL 97
RGD ID: 6480786
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: 5.03
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81234,540,191 - 237,018,045RGD_MAPPER_PIPELINE
mRatBN7.21225,126,575 - 227,604,520RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01245,529,606 - 248,013,094RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.01252,776,360 - 255,263,602RGDRnor_5.0
RGSC_v3.41230,963,695 - 233,551,254RGDRGSC_v3.4
Cross Type: Not Available
Strains Crossed: NMcwi:HS 



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Bw97Ratbody weight  IDA 6893578 RGD 

Experimental Condition
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Bw97Ratcontrol condition  IDA 6893578 RGD 

Measurement Method
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Bw97Ratscale  IDA 6893578 RGD 

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Bw97RatNMcwi:HS  IEA 6893578 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Bw97Ratbody mass  IDA 6893578 RGD 

Disease Annotations     Click to see Annotation Detail View
Weight Gain  (IAGP)

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
body weight  (IDA)

Experimental Condition

Measurement Method
scale  (IDA)

Vertebrate Trait
body mass  (IDA)

Rat Strain
NMcwi:HS  (IEA)

References

References - curated
# Reference Title Reference Citation
1. QTLs registered by Dr. Solberg Woods Personal communication between Dr. Leah Solberg Woods and the RGD curators.
2. Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats. Solberg Woods LC, etal., Physiol Genomics. 2012 Sep 4.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
7700759LOC102555808uncharacterized LOC1025558081234527986234551997Rat
7566943LOC102555989uncharacterized LOC1025559891234705496234747820Rat
402326440LOC134485216uncharacterized LOC1344852161234746948234748363Rat
2325049Eif4e-ps2eukaryotic translation initiation factor 4E, pseudogene 21234784510234785140Rat
1307779Rfx3regulatory factor X31234863462235122989Rat
41377637LOC120100479U6atac minor spliceosomal RNA1234902364234902481Rat
41097335LOC120100391small nucleolar RNA SNORA511234909424234909556Rat
7517961Thoc3-ps1THO complex 3, pseudogene 11235079241235080036Rat
1589453Ppid-ps2peptidylprolyl isomerase D, pseudogene 21235153648235154866Rat
41401218Rnu6-613RNA, U6 small nuclear 6131235384744235384850Rat
1565505Glis3GLIS family zinc finger 31235389567235809416Rat
402434936LOC134485285phosphatidylethanolamine-binding protein 1-like1235707254235725563Rat
41142846LOC120098084uncharacterized LOC1200980841235864623235877708Rat
7715694LOC102546345uncharacterized LOC1025463451235927734235963101Rat
41277114Rnu6-525RNA, U6 small nuclear 5251235955286235955392Rat
3696Slc1a1solute carrier family 1 member 11235963455236043572Rat
1310039Spata6lspermatogenesis associated 6-like1236042960236096530Rat
1566000Plpp6phospholipid phosphatase 61236092642236095494Rat
1588239Phyh-ps1phytanoyl-CoA 2-hydroxylase, pseudogene 11236101986236102879Rat
1565057Tekt5l1tektin 5 like 11236103061236118680Rat
1309295Cdc37l1cell division cycle 37-like 11236118630236147527Rat
619885Ak3adenylate kinase 31236151012236178689Rat
41171347LOC120100015uncharacterized LOC1201000151236193365236208849Rat
1305320Rcl1RNA terminal phosphate cyclase-like 11236238078236282597Rat
2325609Mir101-2microRNA 101-21236273922236274018Rat
402292671LOC134483986uncharacterized LOC1344839861236339149236348079Rat
2939Jak2Janus kinase 21236408905236468769Rat
62061Insl6insulin-like 61236483530236487065Rat
7710008Phb1-ps9prohibitin 1, pseudogene 91236487492236488388Rat
3579Rln1relaxin 11236493532236496541Rat
1306839Plgrktplasminogen receptor with a C-terminal lysine1236512574236526858Rat
1566211Cd274CD274 molecule1236526215236549956Rat
1585881Nip7-ps2nucleolar pre-rRNA processing protein NIP7, pseudogene 21236566540236567062Rat
1306403Pdcd1lg2programmed cell death 1 ligand 21236572497236637490Rat
402212639LOC134485219uncharacterized LOC1344852191236579560236582114Rat
402105587LOC134485217uncharacterized LOC1344852171236607713236609926Rat
1310016Ric1RIC1 homolog, RAB6A GEF complex partner 11236698901236798099Rat
727831Ermp1endoplasmic reticulum metallopeptidase 11236801459236835656Rat
41025615LOC120100017uncharacterized LOC1201000171236845693236857161Rat
41273033LOC120100018uncharacterized LOC1201000181236863040236872554Rat
1306525Mlanamelan-A1236883075236897693Rat
1311595Brd10bromodomain containing 101236904520236984414Rat
11481274LOC10834943360S ribosomal protein L7a pseudogene1236955172236956626Rat
1305165Ranbp6RAN binding protein 61236985930236990451Rat
402446864LOC134485218uncharacterized LOC1344852181236590120236591197Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34009D1Mit341051234540191234540296Ratregion
41392D1Rat3021611236073851236074012Ratregion
42530D1Rat4452041234850482234850686Ratregion
41610D1Rat3002901237017755237018045Ratregion
43423D1Got2281161235238518235238634Ratregion
60222D1Got2241511236489006236489157Ratregion
60224D1Got2292501235566132235566382Ratregion
5032781RH1352771931234810838234811031Ratregion
5070143RH944971321236493592236493724Ratregion
Position Markers

Flank 1: (D1Mit34)
Rat AssemblyChrPosition (strand)Source
GRCr81234,540,191 - 234,540,296 (+)Marker Load Pipeline
mRatBN7.21225,126,575 - 225,126,682 (+)MAPPER
Rnor_6.01245,529,606 - 245,529,710NCBI
Rnor_5.01252,776,360 - 252,776,464UniSTS
RGSC_v3.41230,963,697 - 230,963,799RGD
RGSC_v3.41230,963,695 - 230,963,799UniSTS
Celera1222,301,636 - 222,301,740UniSTS
RGSC_v3.11231,127,720 - 231,127,822RGD
RH 3.4 Map11608.7UniSTS
RH 3.4 Map11608.7RGD
SHRSP x BN Map1125.45UniSTS
SHRSP x BN Map1125.45RGD
FHH x ACI Map1111.25RGD
Cytogenetic Map1 RGD
Peak: (D1Rat302)
Rat AssemblyChrPosition (strand)Source
GRCr81236,073,851 - 236,074,012 (+)Marker Load Pipeline
mRatBN7.21226,660,307 - 226,660,468 (+)MAPPER
Rnor_6.01247,065,439 - 247,065,599NCBI
Rnor_5.01254,305,181 - 254,305,341UniSTS
RGSC_v3.41232,579,832 - 232,579,992UniSTS
RGSC_v3.41232,579,831 - 232,579,992RGD
Celera1223,813,143 - 223,813,303UniSTS
RGSC_v3.11232,743,855 - 232,744,015RGD
RH 3.4 Map11608.6UniSTS
RH 3.4 Map11608.6RGD
SHRSP x BN Map1126.57RGD
SHRSP x BN Map1126.57UniSTS
Cytogenetic Map1q52UniSTS
Flank 2: (D1Rat300)
Rat AssemblyChrPosition (strand)Source
GRCr81237,017,755 - 237,018,045 (+)Marker Load Pipeline
mRatBN7.21227,604,230 - 227,604,520 (+)MAPPER
Rnor_6.01248,012,805 - 248,013,094NCBI
Rnor_5.01255,263,313 - 255,263,602UniSTS
RGSC_v3.41233,550,964 - 233,551,254RGD
RGSC_v3.41233,550,965 - 233,551,254UniSTS
Celera1224,754,487 - 224,754,776UniSTS
RGSC_v3.11233,714,988 - 233,715,277RGD
RH 3.4 Map11617.4RGD
RH 3.4 Map11617.4UniSTS
RH 2.0 Map11178.1RGD


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367243666627Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
8693661Alc34Alcohol consumption QTL 342.20.611drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1234540191270518180Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1221820316234540296Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1233204160270518180Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
634340Hcar5Hepatocarcinoma resistance QTL 58liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1223964326236074012Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
6480786Bw97Body weight QTL 975.03body mass (VT:0001259)body weight (CMO:0000012)1234540191237018045Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
8693618Alc25Alcohol consumption QTL 2530.28drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method: body weight was recorded 6893578
qtl_general number of animals used: 10-21 male rats from the founders and 782 male NMcwi:HS rats 6893578
qtl_general software used:ANOVA 6893578
qtl_map 232.58–233.29 Mb 6893578