Jak2 Mouse (-)-Arctigenin multiple interactions EXP 6480464 arctigenin inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:21426947 Jak2 Mouse (-)-epigallocatechin 3-gallate multiple interactions ISO JAK2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of JAK2 mRNA CTD PMID:22079256 Jak2 Mouse (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 zopolrestat results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 Jak2 Mouse (S)-colchicine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Colchicine promotes the reaction [Uric Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33894285 Jak2 Mouse (S)-nicotine increases response to substance ISO JAK2 (Homo sapiens) 6480464 JAK2 results in increased susceptibility to Nicotine CTD PMID:20943775 Jak2 Mouse (S)-nicotine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Bungarotoxins inhibits the reaction [Nicotine results in increased phosphorylation of JAK2 protein] CTD PMID:34153408 Jak2 Mouse (S)-nicotine increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Nicotine results in increased phosphorylation of JAK2 protein CTD PMID:34153408 Jak2 Mouse (S)-nicotine decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Nicotine results in decreased expression of JAK2 mRNA CTD PMID:29155039 Jak2 Mouse 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of JAK2 mRNA] CTD PMID:22206623 Jak2 Mouse 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of JAK2 mRNA CTD PMID:22206623 Jak2 Mouse 1-naphthyl isothiocyanate increases expression ISO Jak2 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of JAK2 mRNA CTD PMID:25380136 Jak2 Mouse 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 15-deoxy-delta(12 more ... CTD PMID:12847270 Jak2 Mouse 17beta-estradiol multiple interactions ISO JAK2 (Homo sapiens) 6480464 [alpha-cyano-(3 more ... CTD PMID:17272397 more ... Jak2 Mouse 17beta-estradiol increases expression ISO JAK2 (Homo sapiens) 6480464 Estradiol results in increased expression of JAK2 mRNA CTD PMID:26865669 more ... Jak2 Mouse 17beta-estradiol decreases expression ISO JAK2 (Homo sapiens) 6480464 Estradiol results in decreased expression of JAK2 mRNA CTD PMID:19619570 Jak2 Mouse 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Jak2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:27291303 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of JAK2 mRNA CTD PMID:19619570 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Jak2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of JAK2 mRNA CTD PMID:34747641 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of JAK2 mRNA] CTD PMID:22978700 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of JAK2 mRNA CTD PMID:22978700 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of JAK2 mRNA CTD PMID:21570461 and PMID:28213091 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Jak2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of JAK2 mRNA CTD PMID:22298810 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of JAK2 mRNA CTD PMID:17942748 and PMID:18684927 Jak2 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO JAK2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of JAK2 mRNA CTD PMID:19619570 Jak2 Mouse 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] and hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33522063 Jak2 Mouse 2,4,6-trinitrobenzenesulfonic acid increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein CTD PMID:33522063 Jak2 Mouse 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of JAK2 protein CTD PMID:31231976 Jak2 Mouse 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 rhyncophylline inhibits the reaction [4-iodo-2 more ... CTD PMID:31231976 Jak2 Mouse 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA] and IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 Jak2 Mouse 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein CTD PMID:38437956 Jak2 Mouse 2-amino-2-deoxy-D-glucopyranose increases expression ISO Jak2 (Rattus norvegicus) 6480464 Glucosamine results in increased expression of JAK2 mRNA CTD PMID:17109745 Jak2 Mouse 2-ethoxyethanol increases expression ISO Jak2 (Rattus norvegicus) 6480464 2-ethoxyethanol results in increased expression of JAK2 mRNA CTD PMID:19643169 Jak2 Mouse 2-hydroxypropanoic acid decreases expression ISO JAK2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of JAK2 mRNA CTD PMID:30851411 Jak2 Mouse 2-methoxyethanol increases expression ISO Jak2 (Rattus norvegicus) 6480464 methyl cellosolve results in increased expression of JAK2 mRNA CTD PMID:19643169 Jak2 Mouse 2-palmitoylglycerol increases expression ISO JAK2 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of JAK2 mRNA CTD PMID:37199045 Jak2 Mouse 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of JAK2 mRNA CTD PMID:20188158 Jak2 Mouse 3-chloropropane-1,2-diol increases expression ISO Jak2 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of JAK2 mRNA CTD PMID:28522335 Jak2 Mouse 3-methyladenine decreases phosphorylation ISO JAK2 (Homo sapiens) 149735343 3-methyladenine co-treated with anlotinib decreases phosphorylation of JAK2 protein in lung epithelium RGD Jak2 Mouse 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of JAK2 mRNA CTD PMID:22978700 Jak2 Mouse 3-nitropropanoic acid increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 3-nitropropionic acid results in increased phosphorylation of JAK2 protein CTD PMID:38513929 Jak2 Mouse 3-nitropropanoic acid multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 methyllycaconitine inhibits the reaction [Tropisetron inhibits the reaction [3-nitropropionic acid results in increased phosphorylation of JAK2 protein]] and Tropisetron inhibits the reaction [3-nitropropionic acid results in increased phosphorylation of JAK2 protein] CTD PMID:38513929 Jak2 Mouse 3-phenylprop-2-enal multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33522063 Jak2 Mouse 3H-1,2-dithiole-3-thione decreases expression ISO Jak2 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of JAK2 mRNA CTD PMID:19162173 Jak2 Mouse 4,4'-diaminodiphenylmethane increases expression ISO Jak2 (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of JAK2 mRNA CTD PMID:25380136 Jak2 Mouse 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of JAK2 mRNA CTD PMID:19191707 Jak2 Mouse 5-aza-2'-deoxycytidine decreases expression ISO JAK2 (Homo sapiens) 6480464 Decitabine results in decreased expression of JAK2 protein modified form CTD PMID:19379557 Jak2 Mouse 5-aza-2'-deoxycytidine decreases methylation ISO JAK2 (Homo sapiens) 6480464 Decitabine results in decreased methylation of JAK2 promoter CTD PMID:18055864 Jak2 Mouse 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased phosphorylation of JAK2 protein] CTD PMID:24440346 Jak2 Mouse 6-propyl-2-thiouracil decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of JAK2 mRNA CTD PMID:30047161 Jak2 Mouse 7,8-dihydroxycoumarin multiple interactions ISO JAK2 (Homo sapiens) 6480464 alpha-cyano-(3 more ... CTD PMID:37209277 Jak2 Mouse 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Uric Acid results in increased phosphorylation of JAK2 protein CTD PMID:33894285 Jak2 Mouse 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Colchicine promotes the reaction [Uric Acid results in increased phosphorylation of JAK2 protein] and simiaowan promotes the reaction [Uric Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33894285 Jak2 Mouse abamectin increases expression ISO Jak2 (Rattus norvegicus) 6480464 abamectin results in increased expression of JAK2 mRNA CTD PMID:34748272 Jak2 Mouse abamectin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of JAK2 mRNA] CTD PMID:34748272 Jak2 Mouse acetamide increases expression ISO Jak2 (Rattus norvegicus) 6480464 acetamide results in increased expression of JAK2 mRNA CTD PMID:31881176 Jak2 Mouse acetic acid increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Acetic Acid results in increased phosphorylation of JAK2 protein CTD PMID:35122774 Jak2 Mouse acetic acid multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] and Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:35122774 Jak2 Mouse acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester multiple interactions EXP 6480464 nitazoxanide inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of JAK2 protein] and nitazoxanide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] CTD PMID:38663798 Jak2 Mouse acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 nitazoxanide results in decreased phosphorylation of JAK2 protein CTD PMID:38663798 Jak2 Mouse acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of JAK2 mRNA CTD PMID:38152866 Jak2 Mouse acrylamide multiple interactions EXP 6480464 Acrylamide results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:38152866 Jak2 Mouse acrylamide increases expression ISO Jak2 (Rattus norvegicus) 6480464 Acrylamide results in increased expression of JAK2 protein CTD PMID:38152866 Jak2 Mouse actinomycin D multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 Jak2 Mouse afimoxifene multiple interactions ISO JAK2 (Homo sapiens) 6480464 afimoxifene promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] CTD PMID:17272397 Jak2 Mouse aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of JAK2 mRNA CTD PMID:19770486 Jak2 Mouse aldehydo-D-glucosamine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA] and IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 Jak2 Mouse aldehydo-D-glucosamine multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein CTD PMID:38437956 Jak2 Mouse aldehydo-D-glucosamine increases expression ISO Jak2 (Rattus norvegicus) 6480464 Glucosamine results in increased expression of JAK2 mRNA CTD PMID:17109745 Jak2 Mouse aldehydo-D-glucose multiple interactions ISO JAK2 (Homo sapiens) 6480464 (3 more ... CTD PMID:15677497 Jak2 Mouse aldehydo-D-glucose multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein] CTD PMID:20060012 Jak2 Mouse aldehydo-D-glucose increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Glucose results in increased phosphorylation of JAK2 protein CTD PMID:20060012 Jak2 Mouse aldosterone increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Aldosterone results in increased phosphorylation of JAK2 protein CTD PMID:15932931 Jak2 Mouse aldosterone multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] and Spironolactone inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 Jak2 Mouse all-trans-retinoic acid increases expression ISO JAK2 (Homo sapiens) 6480464 Tretinoin results in increased expression of JAK2 mRNA CTD PMID:33167477 Jak2 Mouse all-trans-retinol affects localization ISO Jak2 (Rattus norvegicus) 6480464 Vitamin A affects the localization of JAK2 protein CTD PMID:15963505 Jak2 Mouse aluminium hydroxide multiple interactions EXP 6480464 [Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK2 protein and nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK2 protein] CTD PMID:36029577 Jak2 Mouse amitrole decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Amitrole results in decreased expression of JAK2 mRNA CTD PMID:30047161 Jak2 Mouse amlodipine increases expression ISO JAK2 (Homo sapiens) 6480464 Amlodipine results in increased expression of JAK2 protein modified form CTD PMID:18298949 Jak2 Mouse ammonium chloride affects expression ISO Jak2 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of JAK2 mRNA CTD PMID:16483693 Jak2 Mouse angiotensin II increases phosphorylation ISO JAK2 (Homo sapiens) 127285667 Angiotensin II increases phosphorylation of JAK2 protein in liver RGD Jak2 Mouse antirheumatic drug decreases expression ISO JAK2 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of JAK2 mRNA CTD PMID:24449571 Jak2 Mouse apocynin multiple interactions ISO JAK2 (Homo sapiens) 6480464 acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 Jak2 Mouse arecoline increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Arecoline results in increased phosphorylation of JAK2 protein CTD PMID:34999050 Jak2 Mouse arsane affects methylation ISO JAK2 (Homo sapiens) 6480464 Arsenic affects the methylation of JAK2 gene CTD PMID:25304211 Jak2 Mouse arsane increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Arsenic results in increased phosphorylation of JAK2 protein CTD PMID:35031324 Jak2 Mouse arsenic atom affects methylation ISO JAK2 (Homo sapiens) 6480464 Arsenic affects the methylation of JAK2 gene CTD PMID:25304211 Jak2 Mouse arsenic atom increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Arsenic results in increased phosphorylation of JAK2 protein CTD PMID:35031324 Jak2 Mouse arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of JAK2 protein CTD PMID:35088608 Jak2 Mouse arsenous acid decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased phosphorylation of JAK2 protein CTD PMID:29409467 Jak2 Mouse arsenous acid increases expression ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of JAK2 mRNA CTD PMID:29633893 Jak2 Mouse arsenous acid multiple interactions ISO JAK2 (Homo sapiens) 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein more ... CTD PMID:12492118 more ... Jak2 Mouse arsenous acid decreases expression ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of JAK2 protein CTD PMID:11721366 and PMID:36352148 Jak2 Mouse arsenous acid multiple interactions EXP 6480464 baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JAK2 protein] CTD PMID:35088608 Jak2 Mouse auranofin multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein CTD PMID:20542334 Jak2 Mouse baicalin multiple interactions EXP 6480464 baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JAK2 protein] CTD PMID:35088608 Jak2 Mouse Bardoxolone methyl multiple interactions EXP 6480464 bardoxolone methyl inhibits the reaction [Dietary Fats results in decreased phosphorylation of JAK2 protein] CTD PMID:27417254 Jak2 Mouse baricitinib multiple interactions ISO JAK2 (Homo sapiens) 6480464 baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:23968543 Jak2 Mouse baricitinib decreases activity ISO JAK2 (Homo sapiens) 6480464 baricitinib results in decreased activity of JAK2 protein CTD PMID:29687421 Jak2 Mouse benzo[a]pyrene decreases expression ISO JAK2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of JAK2 mRNA CTD PMID:20064835 Jak2 Mouse benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of JAK2 mRNA CTD PMID:22228805 Jak2 Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of JAK2 mRNA CTD PMID:22228805 Jak2 Mouse beta-D-glucosamine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA] and IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 Jak2 Mouse beta-D-glucosamine multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein CTD PMID:38437956 Jak2 Mouse beta-D-glucosamine increases expression ISO Jak2 (Rattus norvegicus) 6480464 Glucosamine results in increased expression of JAK2 mRNA CTD PMID:17109745 Jak2 Mouse beta-Elemonic acid decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 beta-elemonic acid results in decreased phosphorylation of JAK2 protein CTD PMID:33878321 Jak2 Mouse bisphenol A multiple interactions ISO JAK2 (Homo sapiens) 6480464 [alpha-cyano-(3 more ... CTD PMID:23850738 Jak2 Mouse bisphenol A decreases expression ISO JAK2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of JAK2 mRNA CTD PMID:36232920 Jak2 Mouse bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of JAK2 protein CTD PMID:30609183 Jak2 Mouse bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of JAK2 promoter CTD PMID:27824486 Jak2 Mouse bisphenol A increases methylation ISO Jak2 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of JAK2 gene CTD PMID:28505145 Jak2 Mouse bisphenol A increases expression ISO JAK2 (Homo sapiens) 6480464 bisphenol A results in increased expression of JAK2 mRNA CTD PMID:28711546 Jak2 Mouse bisphenol A increases expression ISO Jak2 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of JAK2 mRNA CTD PMID:25181051 more ... Jak2 Mouse bisphenol F multiple interactions EXP 6480464 alpha-cyano-(3 more ... CTD PMID:32044397 Jak2 Mouse bisphenol F increases phosphorylation EXP 6480464 4 and 4'-bisphenol F results in increased phosphorylation of JAK2 protein CTD PMID:32044397 Jak2 Mouse butyric acid decreases expression ISO JAK2 (Homo sapiens) 6480464 Butyric Acid results in decreased expression of JAK2 mRNA CTD PMID:34581912 Jak2 Mouse cadmium atom multiple interactions EXP 6480464 [Cadmium co-treated with Dietary Fats] results in increased phosphorylation of JAK2 protein CTD PMID:34998821 Jak2 Mouse cadmium dichloride decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased phosphorylation of JAK2 protein CTD PMID:19635391 Jak2 Mouse cadmium dichloride decreases expression ISO JAK2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of JAK2 mRNA CTD PMID:38568856 Jak2 Mouse calciol increases expression EXP 6480464 Cholecalciferol results in increased expression of JAK2 mRNA CTD PMID:17170073 Jak2 Mouse calcium atom multiple interactions EXP 6480464 JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 Jak2 Mouse calcium(0) multiple interactions EXP 6480464 JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 Jak2 Mouse cannabidiol multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of JAK2 mRNA CTD PMID:30096889 Jak2 Mouse capillarisin multiple interactions ISO JAK2 (Homo sapiens) 6480464 pervanadate inhibits the reaction [capillarisin results in decreased phosphorylation of JAK2 protein] CTD PMID:24333736 Jak2 Mouse capillarisin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 capillarisin results in decreased phosphorylation of JAK2 protein CTD PMID:24333736 Jak2 Mouse carbon nanotube multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Nanotubes and Carbon] results in increased expression of JAK2 protein CTD PMID:38285958 Jak2 Mouse ceruletide multiple interactions EXP 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Ceruletide results in increased expression of JAK2 protein]] more ... CTD PMID:34423886 Jak2 Mouse ceruletide increases expression EXP 6480464 Ceruletide results in increased expression of JAK2 protein CTD PMID:34423886 Jak2 Mouse chelerythrine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 chelerythrine results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 Jak2 Mouse chloroquine decreases phosphorylation ISO JAK2 (Homo sapiens) 149735343 chloroquine co-treated with anlotinib decreases phosphorylation of JAK2 protein in lung epithelium RGD Jak2 Mouse chlorpyrifos increases phosphorylation EXP 6480464 Chlorpyrifos results in increased phosphorylation of JAK2 protein CTD PMID:29404631 Jak2 Mouse Cirsimarin multiple interactions EXP 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] CTD PMID:30053449 Jak2 Mouse cisplatin increases prenylation EXP 149735351 cisplatin increases phosphorylation of Jak2 protein in kidney RGD Jak2 Mouse cisplatin decreases expression ISO JAK2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of JAK2 mRNA CTD PMID:27392435 Jak2 Mouse cisplatin decreases phosphorylation ISO JAK2 (Homo sapiens) 127284886 cisplatin decreases phosphorylation of JAK2 protein in stomach RGD Jak2 Mouse cisplatin increases expression EXP 149735351 cisplatin increases expression of Jak2 mRNA in kidney RGD Jak2 Mouse clomiphene decreases expression ISO JAK2 (Homo sapiens) 6480464 Clomiphene results in decreased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse clothianidin decreases expression ISO JAK2 (Homo sapiens) 6480464 clothianidin results in decreased expression of JAK2 mRNA CTD PMID:31626844 Jak2 Mouse clozapine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 [[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein more ... CTD PMID:18976543 Jak2 Mouse cocaine multiple interactions EXP 6480464 alpha-cyano-(3 more ... CTD PMID:29673861 Jak2 Mouse cocaine increases phosphorylation EXP 6480464 Cocaine results in increased phosphorylation of JAK2 protein CTD PMID:29673861 Jak2 Mouse coniferyl aldehyde multiple interactions EXP 6480464 coniferaldehyde inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:27378624 Jak2 Mouse coniferyl aldehyde multiple interactions ISO JAK2 (Homo sapiens) 6480464 coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein] CTD PMID:27378624 Jak2 Mouse copper atom multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of JAK2 mRNA CTD PMID:30911355 Jak2 Mouse copper(0) multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of JAK2 mRNA CTD PMID:30911355 Jak2 Mouse cordycepin increases phosphorylation EXP 6480464 cordycepin results in increased phosphorylation of JAK2 protein CTD PMID:32042022 Jak2 Mouse cordycepin multiple interactions EXP 6480464 alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [cordycepin results in increased phosphorylation of JAK2 protein] CTD PMID:32042022 Jak2 Mouse corticosterone multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 [alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [HTR2A protein results in increased secretion of Corticosterone] CTD PMID:19304867 Jak2 Mouse coumermycin A1 increases expression EXP 6480464 coumermycin results in increased expression of JAK2 protein CTD PMID:34423886 Jak2 Mouse coumermycin A1 multiple interactions EXP 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased expression of JAK2 protein]] and coumermycin inhibits the reaction [limonin inhibits the reaction [Ceruletide results in increased expression of JAK2 protein]] CTD PMID:34423886 Jak2 Mouse crocin-1 multiple interactions ISO JAK2 (Homo sapiens) 6480464 crocin affects the expression of and affects the phosphorylation of JAK2 protein CTD PMID:32886819 Jak2 Mouse cucurbitacin I multiple interactions ISO JAK2 (Homo sapiens) 6480464 cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:19153190 Jak2 Mouse Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of JAK2 protein modified form CTD PMID:29864483 Jak2 Mouse Cuprizon multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of JAK2 protein modified form] CTD PMID:29864483 Jak2 Mouse curcumin decreases expression ISO JAK2 (Homo sapiens) 6480464 Curcumin results in decreased expression of JAK2 protein CTD PMID:16959222 and PMID:36352148 Jak2 Mouse curcumin multiple interactions ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide promotes the reaction [Curcumin results in decreased expression of JAK2 protein] and Curcumin inhibits the reaction [Trichloroethylene results in increased phosphorylation of JAK2 protein] CTD PMID:34233590 and PMID:36352148 Jak2 Mouse cyclosporin A increases activity EXP 6480464 Cyclosporine results in increased activity of JAK2 protein CTD PMID:22155090 Jak2 Mouse cyclosporin A increases expression ISO JAK2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of JAK2 mRNA CTD PMID:20106945 more ... Jak2 Mouse cyclosporin A increases phosphorylation EXP 6480464 Cyclosporine results in increased phosphorylation of JAK2 protein CTD PMID:23958496 Jak2 Mouse cyclosporin A multiple interactions EXP 6480464 sulforaphane inhibits the reaction [Cyclosporine results in increased phosphorylation of JAK2 protein] CTD PMID:23958496 Jak2 Mouse cyhalothrin increases expression ISO Jak2 (Rattus norvegicus) 6480464 cyhalothrin results in increased expression of JAK2 protein CTD PMID:37060950 Jak2 Mouse cypermethrin increases expression ISO Jak2 (Rattus norvegicus) 6480464 cypermethrin results in increased expression of JAK2 mRNA CTD PMID:35876585 Jak2 Mouse cypermethrin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [cypermethrin results in increased expression of JAK2 mRNA] CTD PMID:35876585 Jak2 Mouse D-glucose multiple interactions ISO JAK2 (Homo sapiens) 6480464 (3 more ... CTD PMID:15677497 Jak2 Mouse D-glucose increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Glucose results in increased phosphorylation of JAK2 protein CTD PMID:20060012 Jak2 Mouse D-glucose multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein] CTD PMID:20060012 Jak2 Mouse dapagliflozin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein] CTD PMID:34391751 Jak2 Mouse daunorubicin decreases expression ISO JAK2 (Homo sapiens) 6480464 Daunorubicin results in decreased expression of JAK2 mRNA CTD PMID:26537877 and PMID:28940058 Jak2 Mouse decabromodiphenyl ether increases expression ISO Jak2 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of JAK2 mRNA CTD PMID:23640034 Jak2 Mouse delphinidin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 delphinidin results in decreased phosphorylation of JAK2 protein CTD PMID:33955636 Jak2 Mouse deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of JAK2 mRNA CTD PMID:22454431 Jak2 Mouse deoxynivalenol multiple interactions EXP 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 and PMID:38432439 Jak2 Mouse dextran sulfate multiple interactions EXP 6480464 BCL6 protein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein] more ... CTD PMID:32272095 more ... Jak2 Mouse dextran sulfate increases phosphorylation EXP 6480464 Dextran Sulfate results in increased phosphorylation of JAK2 protein CTD PMID:32272095 more ... Jak2 Mouse diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of JAK2 protein CTD PMID:35088608 Jak2 Mouse diarsenic trioxide increases expression ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of JAK2 mRNA CTD PMID:29633893 Jak2 Mouse diarsenic trioxide decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased phosphorylation of JAK2 protein CTD PMID:29409467 Jak2 Mouse diarsenic trioxide decreases expression ISO JAK2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of JAK2 protein CTD PMID:11721366 and PMID:36352148 Jak2 Mouse diarsenic trioxide multiple interactions ISO JAK2 (Homo sapiens) 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein more ... CTD PMID:12492118 more ... Jak2 Mouse diarsenic trioxide multiple interactions EXP 6480464 baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JAK2 protein] CTD PMID:35088608 Jak2 Mouse Dibutyl phosphate affects expression ISO JAK2 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of JAK2 mRNA CTD PMID:37042841 Jak2 Mouse dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of JAK2 mRNA CTD PMID:21266533 Jak2 Mouse dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Nanotubes and Carbon] results in increased expression of JAK2 protein CTD PMID:38285958 Jak2 Mouse dieldrin decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Dieldrin results in decreased expression of JAK2 mRNA CTD PMID:34051100 Jak2 Mouse diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of JAK2 mRNA CTD PMID:15591538 Jak2 Mouse diethylstilbestrol increases expression ISO JAK2 (Homo sapiens) 6480464 Diethylstilbestrol results in increased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse dimethylarsinic acid decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Cacodylic Acid results in decreased expression of JAK2 mRNA CTD PMID:17720352 Jak2 Mouse dimethylarsinic acid multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Cacodylic Acid results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:32890875 Jak2 Mouse dioxygen increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Oxygen deficiency results in increased phosphorylation of JAK2 protein CTD PMID:29685624 Jak2 Mouse dioxygen multiple interactions ISO JAK2 (Homo sapiens) 6480464 alpha-cyano-(3 more ... CTD PMID:29685624 Jak2 Mouse diquat increases expression EXP 6480464 Diquat results in increased expression of JAK2 protein CTD PMID:36851058 Jak2 Mouse divanadium pentaoxide decreases expression ISO JAK2 (Homo sapiens) 6480464 vanadium pentoxide results in decreased expression of JAK2 mRNA CTD PMID:17459161 Jak2 Mouse doxorubicin decreases expression ISO JAK2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of JAK2 mRNA CTD PMID:26537877 more ... Jak2 Mouse doxorubicin multiple interactions EXP 6480464 Doxorubicin promotes the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] and thymoquinone inhibits the reaction [Doxorubicin results in increased phosphorylation of JAK2 protein] CTD PMID:34605108 Jak2 Mouse doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of JAK2 protein CTD PMID:34605108 Jak2 Mouse emodin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Emodin results in decreased phosphorylation of JAK2 protein CTD PMID:23848338 Jak2 Mouse emodin multiple interactions ISO JAK2 (Homo sapiens) 6480464 Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein] CTD PMID:23848338 Jak2 Mouse eriocitrin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 eriocitrin results in decreased phosphorylation of JAK2 protein CTD PMID:34724282 Jak2 Mouse erlotinib hydrochloride decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of JAK2 protein CTD PMID:23894143 Jak2 Mouse estrone increases expression ISO JAK2 (Homo sapiens) 6480464 Estrone results in increased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse ethanol affects expression EXP 6480464 Ethanol affects the expression of JAK2 mRNA CTD PMID:30319688 Jak2 Mouse ethyl methanesulfonate increases expression ISO JAK2 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of JAK2 mRNA CTD PMID:23649840 Jak2 Mouse flutamide decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Flutamide results in decreased expression of JAK2 mRNA CTD PMID:24793618 Jak2 Mouse folic acid multiple interactions ISO JAK2 (Homo sapiens) 6480464 alpha-cyano-(3 more ... CTD PMID:29685624 Jak2 Mouse folic acid multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of JAK2 mRNA] CTD PMID:22206623 Jak2 Mouse fraxetin decreases phosphorylation ISO JAK2 (Homo sapiens) 125097526 Fraxetin decreases phosphorylation of JAK2 protein in colorectum RGD Jak2 Mouse fructose decreases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Fructose results in decreased phosphorylation of JAK2 protein CTD PMID:22426011 Jak2 Mouse fructose multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] and Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] CTD PMID:22426011 Jak2 Mouse fucoxanthin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 fucoxanthin results in decreased phosphorylation of JAK2 protein CTD PMID:38444163 Jak2 Mouse fulvestrant decreases expression ISO JAK2 (Homo sapiens) 6480464 fulvestrant results in decreased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [4 and 4'-bisphenol F results in increased phosphorylation of JAK2 protein] CTD PMID:32044397 Jak2 Mouse fulvestrant decreases phosphorylation EXP 6480464 Fulvestrant results in decreased phosphorylation of JAK2 protein CTD PMID:32044397 Jak2 Mouse furan increases methylation ISO Jak2 (Rattus norvegicus) 6480464 furan results in increased methylation of JAK2 gene CTD PMID:22079235 Jak2 Mouse galaxolide increases expression ISO JAK2 (Homo sapiens) 6480464 galaxolide results in increased expression of JAK2 mRNA CTD PMID:34687775 Jak2 Mouse galaxolide multiple interactions ISO JAK2 (Homo sapiens) 6480464 [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of JAK2 mRNA CTD PMID:34687775 Jak2 Mouse Ganoderic acid A multiple interactions EXP 6480464 ganoderic acid A inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK2 protein] CTD PMID:34029542 Jak2 Mouse genistein increases expression ISO JAK2 (Homo sapiens) 6480464 Genistein results in increased expression of JAK2 mRNA CTD PMID:26865667 and PMID:26865669 Jak2 Mouse Gingerenone A increases response to substance ISO JAK2 (Homo sapiens) 6480464 JAK2 protein results in increased susceptibility to gingerenone A CTD PMID:26242912 Jak2 Mouse Gingerenone A decreases activity ISO JAK2 (Homo sapiens) 6480464 gingerenone A results in decreased activity of JAK2 protein CTD PMID:26242912 and PMID:33050000 Jak2 Mouse Ginkgoic acid decreases phosphorylation ISO JAK2 (Homo sapiens) 127284886 Ginkgoic acid decreases phosphorylation of JAK2 protein in stomach RGD Jak2 Mouse glucose multiple interactions ISO JAK2 (Homo sapiens) 6480464 (3 more ... CTD PMID:15677497 Jak2 Mouse glucose increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Glucose results in increased phosphorylation of JAK2 protein CTD PMID:20060012 Jak2 Mouse glucose multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein] CTD PMID:20060012 Jak2 Mouse glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [15-deoxy-delta(12 more ... CTD PMID:12847270 Jak2 Mouse Goe 6976 multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Go 6976 results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 Jak2 Mouse Goe 6976 multiple interactions EXP 6480464 Go 6976 results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 Jak2 Mouse gold atom multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 Jak2 Mouse gold(0) multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 Jak2 Mouse hesperetin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:33522063 Jak2 Mouse hesperidin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Hesperidin inhibits the reaction [abamectin results in increased expression of JAK2 mRNA] CTD PMID:34748272 Jak2 Mouse hexadecanoic acid multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA CTD PMID:30547786 Jak2 Mouse hexestrol increases expression ISO JAK2 (Homo sapiens) 6480464 Hexestrol results in increased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse hispidulin decreases phosphorylation ISO JAK2 (Homo sapiens) 149735333 hispidulin decreases phoshphorylation of JAK2 protein in colon and colorectum RGD Jak2 Mouse hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein] CTD PMID:12847270 Jak2 Mouse hydrogen peroxide decreases expression ISO JAK2 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of JAK2 mRNA CTD PMID:34581912 Jak2 Mouse hydrogen peroxide decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased phosphorylation of JAK2 protein CTD PMID:19635391 Jak2 Mouse ivermectin multiple interactions ISO JAK2 (Homo sapiens) 6480464 AZD 1480 inhibits the reaction [SLC2A4 protein inhibits the reaction [Ivermectin results in decreased expression of JAK2 protein]] and SLC2A4 protein inhibits the reaction [Ivermectin results in decreased expression of JAK2 protein] CTD PMID:34904774 Jak2 Mouse ivermectin decreases expression ISO JAK2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of JAK2 protein CTD PMID:34904774 Jak2 Mouse kainic acid decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Kainic Acid results in decreased expression of JAK2 protein CTD PMID:18711747 Jak2 Mouse kainic acid multiple interactions ISO JAK2 (Homo sapiens) 6480464 EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein] and EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]] CTD PMID:18711747 Jak2 Mouse ketamine decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Ketamine results in decreased expression of JAK2 mRNA CTD PMID:20080153 Jak2 Mouse L-arginine multiple interactions EXP 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased expression of JAK2 protein]] more ... CTD PMID:34423886 Jak2 Mouse L-arginine increases expression EXP 6480464 Arginine results in increased expression of JAK2 protein CTD PMID:34423886 Jak2 Mouse lactucin multiple interactions EXP 6480464 lactucin affects the reaction [Dietary Fats affects the phosphorylation of JAK2 protein] CTD PMID:32023857 Jak2 Mouse lapatinib multiple interactions ISO JAK2 (Homo sapiens) 6480464 Lapatinib inhibits the reaction [sodium arsenite results in increased phosphorylation of JAK2 protein] CTD PMID:32890875 Jak2 Mouse limonin multiple interactions EXP 6480464 coumermycin inhibits the reaction [limonin inhibits the reaction [Arginine results in increased expression of JAK2 protein]] more ... CTD PMID:34423886 Jak2 Mouse linagliptin multiple interactions EXP 6480464 Linagliptin inhibits the reaction [Cuprizone results in increased expression of JAK2 protein modified form] CTD PMID:29864483 Jak2 Mouse linagliptin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Linagliptin inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:35122774 Jak2 Mouse lipopolysaccharide increases activity EXP 6480464 [Lipopolysaccharides results in increased activity of JAK2 protein] which results in increased activity of STAT3 protein and Lipopolysaccharides results in increased activity of JAK2 protein CTD PMID:24486434 Jak2 Mouse lipopolysaccharide increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Lipopolysaccharides results in increased phosphorylation of JAK2 protein CTD PMID:37209277 and PMID:38437956 Jak2 Mouse lipopolysaccharide multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein more ... CTD PMID:37209277 and PMID:38437956 Jak2 Mouse lipopolysaccharide multiple interactions EXP 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] more ... CTD PMID:28839360 more ... Jak2 Mouse lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of JAK2 protein CTD PMID:25576658 more ... Jak2 Mouse loliolide multiple interactions ISO JAK2 (Homo sapiens) 6480464 loliolide inhibits the reaction [SOD2 protein results in increased phosphorylation of JAK2 protein] CTD PMID:36707041 Jak2 Mouse losartan multiple interactions ISO JAK2 (Homo sapiens) 127285667 losartan inhibits the reaction [Angiotensin II increases phosphorylation of JAK2 protein in liver] RGD Jak2 Mouse LY294002 multiple interactions EXP 149735351 LY294002 inhibits the reaction [cisplatin increases phosphorylation of Jak2 protein in kidney] RGD Jak2 Mouse melittin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Melitten results in decreased phosphorylation of JAK2 protein CTD PMID:22027265 Jak2 Mouse melphalan decreases expression ISO JAK2 (Homo sapiens) 6480464 Melphalan results in decreased expression of JAK2 mRNA CTD PMID:22363485 Jak2 Mouse mercury atom affects expression ISO JAK2 (Homo sapiens) 6480464 Mercury affects the expression of JAK2 mRNA CTD PMID:23920476 Jak2 Mouse mercury dichloride decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Mercuric Chloride results in decreased phosphorylation of JAK2 protein CTD PMID:16896058 and PMID:19635391 Jak2 Mouse mercury(0) affects expression ISO JAK2 (Homo sapiens) 6480464 Mercury affects the expression of JAK2 mRNA CTD PMID:23920476 Jak2 Mouse mesalamine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Mesalamine inhibits the reaction [Acetic Acid results in increased phosphorylation of JAK2 protein] CTD PMID:35122774 Jak2 Mouse mestranol increases expression ISO JAK2 (Homo sapiens) 6480464 Mestranol results in increased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse methimazole decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Methimazole results in decreased expression of JAK2 mRNA CTD PMID:30047161 Jak2 Mouse methyl methanesulfonate increases expression ISO JAK2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of JAK2 mRNA CTD PMID:23649840 Jak2 Mouse methyllycaconitine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 methyllycaconitine inhibits the reaction [Tropisetron inhibits the reaction [3-nitropropionic acid results in increased phosphorylation of JAK2 protein]] CTD PMID:38513929 Jak2 Mouse methylmercury chloride affects phosphorylation EXP 6480464 methylmercuric chloride affects the phosphorylation of JAK2 protein CTD PMID:33338554 Jak2 Mouse Methylthiouracil multiple interactions ISO JAK2 (Homo sapiens) 6480464 Methylthiouracil inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:26298005 Jak2 Mouse mevalonic acid multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]] CTD PMID:16534557 Jak2 Mouse microcystin-LR multiple interactions ISO JAK2 (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:36115647 Jak2 Mouse microcystin-LR multiple interactions EXP 6480464 cyanoginosin LR results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:36115647 Jak2 Mouse mitoxantrone decreases expression ISO JAK2 (Homo sapiens) 6480464 Mitoxantrone results in decreased expression of JAK2 mRNA CTD PMID:26537877 and PMID:28940058 Jak2 Mouse Monobutylphthalate increases phosphorylation EXP 6480464 monobutyl phthalate results in increased phosphorylation of JAK2 protein CTD PMID:35278568 Jak2 Mouse Monobutylphthalate multiple interactions EXP 6480464 alpha-cyano-(3 and 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [monobutyl phthalate results in increased phosphorylation of JAK2 protein] CTD PMID:35278568 Jak2 Mouse N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of JAK2 protein] CTD PMID:31231976 Jak2 Mouse N-acetyl-L-cysteine multiple interactions ISO JAK2 (Homo sapiens) 127284846 N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of JAK2 protein in the stomach) RGD Jak2 Mouse N-acetyl-L-cysteine multiple interactions ISO JAK2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein] and Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] CTD PMID:29894800 and PMID:34627931 Jak2 Mouse N-acetyl-L-cysteine multiple interactions ISO JAK2 (Homo sapiens) 127284886 N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid decreases phosphorylation of JAK2 protein in stomach] RGD Jak2 Mouse N-acetyl-L-cysteine multiple interactions ISO JAK2 (Homo sapiens) 149735333 N-acetyl-L-cysteine inhibits the reaction [hispidulin decreases phoshphorylation of JAK2 protein in colon and colorectum] RGD Jak2 Mouse N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [15-deoxy-delta(12 more ... CTD PMID:12847270 Jak2 Mouse N-nitrosodiethylamine increases phosphorylation EXP 127285675 N-nitrosodiethylamine increases phosphorylation of JAK2 protein in liver RGD Jak2 Mouse N-nitrosodiethylamine increases expression ISO Jak2 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of JAK2 protein CTD PMID:29698782 Jak2 Mouse N-nitrosodiethylamine decreases response to substance EXP 6480464 JAK2 gene mutant form results in decreased susceptibility to Diethylnitrosamine CTD PMID:28100771 Jak2 Mouse N-nitrosodimethylamine increases expression ISO Jak2 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased expression of JAK2 mRNA CTD PMID:25380136 Jak2 Mouse nickel atom multiple interactions ISO JAK2 (Homo sapiens) 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of JAK2 mRNA] CTD PMID:14575637 Jak2 Mouse nickel atom increases expression ISO JAK2 (Homo sapiens) 6480464 Nickel results in increased expression of JAK2 mRNA CTD PMID:24768652 and PMID:25583101 Jak2 Mouse nickel atom decreases expression ISO JAK2 (Homo sapiens) 6480464 Nickel results in decreased expression of JAK2 mRNA CTD PMID:23195993 Jak2 Mouse nickel atom affects expression ISO JAK2 (Homo sapiens) 6480464 Nickel affects the expression of JAK2 mRNA CTD PMID:14575637 Jak2 Mouse nickel dichloride affects expression ISO Jak2 (Rattus norvegicus) 6480464 nickel chloride affects the expression of JAK2 mRNA CTD PMID:22546817 Jak2 Mouse nicotine increases response to substance ISO JAK2 (Homo sapiens) 6480464 JAK2 results in increased susceptibility to Nicotine CTD PMID:20943775 Jak2 Mouse nicotine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Bungarotoxins inhibits the reaction [Nicotine results in increased phosphorylation of JAK2 protein] CTD PMID:34153408 Jak2 Mouse nicotine increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Nicotine results in increased phosphorylation of JAK2 protein CTD PMID:34153408 Jak2 Mouse nicotine decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Nicotine results in decreased expression of JAK2 mRNA CTD PMID:29155039 Jak2 Mouse nimesulide decreases phosphorylation ISO JAK2 (Homo sapiens) 127285656 Nimesulide decreases phoshphorylation of JAK2 in esophagus squamous epithelium RGD Jak2 Mouse nitric oxide multiple interactions EXP 6480464 JAK2 protein promotes the reaction [IFNG protein results in increased abundance of Nitric Oxide] CTD PMID:12847270 Jak2 Mouse nitric oxide decreases expression EXP 6480464 Nitric Oxide deficiency results in decreased expression of JAK2 mRNA CTD PMID:15878706 Jak2 Mouse Nonylphenol multiple interactions EXP 6480464 nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK2 protein] CTD PMID:36029577 Jak2 Mouse okadaic acid multiple interactions ISO JAK2 (Homo sapiens) 6480464 JAK2 protein affects the reaction [[PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in decreased susceptibility to Okadaic Acid] CTD PMID:21715663 Jak2 Mouse olanzapine multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 [[olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein more ... CTD PMID:18976543 and PMID:19304867 Jak2 Mouse olanzapine increases activity ISO Jak2 (Rattus norvegicus) 6480464 olanzapine results in increased activity of JAK2 protein CTD PMID:19304867 Jak2 Mouse oleic acid multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA CTD PMID:30547786 Jak2 Mouse ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of JAK2 mRNA and Ozone results in increased expression of and results in increased phosphorylation of JAK2 protein CTD PMID:26949510 and PMID:27106289 Jak2 Mouse pantoprazole multiple interactions EXP 127285673 pantoprazole decreases expression of JAK2 mRNA and decreases phosphorylation of JAK2 protein in gastrocnemius RGD Jak2 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of JAK2 mRNA CTD PMID:17562736 Jak2 Mouse paroxetine multiple interactions ISO JAK2 (Homo sapiens) 6480464 LY 215840 promotes the reaction [Paroxetine results in increased expression of JAK2 mRNA] CTD PMID:32020710 Jak2 Mouse paroxetine increases expression ISO JAK2 (Homo sapiens) 6480464 Paroxetine results in increased expression of JAK2 mRNA CTD PMID:32020710 Jak2 Mouse PD123319 multiple interactions ISO JAK2 (Homo sapiens) 127285667 PD123319 co-treated with losartan inhibits the reaction [Angiotensin II increases phosphorylation of JAK2 protein in liver] RGD Jak2 Mouse perfluorooctane-1-sulfonic acid decreases expression ISO JAK2 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of JAK2 mRNA CTD PMID:27153767 Jak2 Mouse perfluorooctanoic acid increases expression ISO JAK2 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of JAK2 mRNA CTD PMID:36326898 Jak2 Mouse phenylpropanolamine increases expression ISO Jak2 (Rattus norvegicus) 6480464 Phenylpropanolamine results in increased expression of JAK2 mRNA and Phenylpropanolamine results in increased expression of JAK2 protein CTD PMID:24792324 Jak2 Mouse PhIP increases expression ISO JAK2 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of JAK2 mRNA CTD PMID:29362861 Jak2 Mouse phosphane decreases expression ISO Jak2 (Rattus norvegicus) 6480464 phosphine results in decreased expression of JAK2 mRNA CTD PMID:34427094 Jak2 Mouse phosphatidic acid increases phosphorylation EXP 6480464 Phosphatidic Acids results in increased phosphorylation of JAK2 protein CTD PMID:16354768 Jak2 Mouse pipoxolan multiple interactions EXP 6480464 pipoxolan inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:32677756 Jak2 Mouse pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of JAK2 mRNA CTD PMID:18445702 Jak2 Mouse platycodin D decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 platycodin D results in decreased phosphorylation of JAK2 protein CTD PMID:25250884 Jak2 Mouse PNU-282987 multiple interactions ISO JAK2 (Homo sapiens) 6480464 [1-(5-chloro-2 more ... CTD PMID:21715663 Jak2 Mouse ponatinib decreases activity ISO JAK2 (Homo sapiens) 6480464 ponatinib results in decreased activity of JAK2 protein CTD PMID:19878872 Jak2 Mouse Ponicidin decreases phosphorylation ISO JAK2 (Homo sapiens) 127285620 Ponicidin decreases phosphorylation of JAK2 protein in the stomach RGD Jak2 Mouse potassium chromate decreases expression ISO JAK2 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of JAK2 mRNA CTD PMID:22079256 Jak2 Mouse potassium chromate multiple interactions ISO JAK2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of JAK2 mRNA CTD PMID:22079256 Jak2 Mouse potassium dichromate multiple interactions ISO JAK2 (Homo sapiens) 6480464 Potassium Dichromate results in decreased expression of and results in decreased phosphorylation of JAK2 protein CTD PMID:37146930 Jak2 Mouse PRIM-O-GLUCOSYLCIMIFUGIN multiple interactions EXP 6480464 prim-O-glucosylcimifugin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] CTD PMID:28839360 Jak2 Mouse progesterone increases expression ISO JAK2 (Homo sapiens) 6480464 Progesterone results in increased expression of JAK2 mRNA CTD PMID:20864642 Jak2 Mouse propofol decreases phosphorylation ISO JAK2 (Homo sapiens) 125097524 Propofol decreases phosphorylation of JAK2 protein in colon epithelium RGD Jak2 Mouse pterostilbene decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 pterostilbene results in decreased phosphorylation of JAK2 protein CTD PMID:23313376 Jak2 Mouse quercetin decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Quercetin analog results in decreased expression of JAK2 protein CTD PMID:23907460 Jak2 Mouse quercetin multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 Jak2 Mouse quercetin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of JAK2 protein CTD PMID:24275163 Jak2 Mouse quercetin increases expression ISO JAK2 (Homo sapiens) 6480464 Quercetin results in increased expression of JAK2 mRNA CTD PMID:21632981 Jak2 Mouse quercetin decreases phosphorylation EXP 6480464 Quercetin results in decreased phosphorylation of JAK2 protein CTD PMID:24275163 Jak2 Mouse quercetin increases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Quercetin analog results in increased phosphorylation of JAK2 protein CTD PMID:23907460 Jak2 Mouse quercetin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 alpha-cyano-(3 more ... CTD PMID:22426011 more ... Jak2 Mouse quercetin 3-O-beta-D-glucofuranoside increases expression ISO JAK2 (Homo sapiens) 6480464 isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 Jak2 Mouse quercetin 3-O-beta-D-glucopyranoside increases expression ISO JAK2 (Homo sapiens) 6480464 isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 Jak2 Mouse rac-lactic acid decreases expression ISO JAK2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of JAK2 mRNA CTD PMID:30851411 Jak2 Mouse raloxifene multiple interactions ISO JAK2 (Homo sapiens) 6480464 Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] CTD PMID:17272397 Jak2 Mouse raloxifene decreases expression ISO JAK2 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased expression of JAK2 mRNA CTD PMID:26865669 Jak2 Mouse reactive oxygen species increases activity ISO JAK2 (Homo sapiens) 6480464 Reactive Oxygen Species results in increased activity of JAK2 protein CTD PMID:20523355 Jak2 Mouse resveratrol decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of JAK2 protein CTD PMID:23372833 more ... Jak2 Mouse resveratrol multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of JAK2 mRNA and Resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK2 protein] CTD PMID:23557933 and PMID:38437956 Jak2 Mouse resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with alpha-cyano-(3 more ... CTD PMID:31881177 more ... Jak2 Mouse Rhynchophylline multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 rhyncophylline inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of JAK2 protein] CTD PMID:31231976 Jak2 Mouse rotenone multiple interactions ISO JAK2 (Homo sapiens) 6480464 Rotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of JAK2 protein] and Rotenone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 and PMID:15748169 Jak2 Mouse rotenone decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Rotenone results in decreased phosphorylation of JAK2 protein CTD PMID:19635391 Jak2 Mouse rutin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] CTD PMID:22426011 Jak2 Mouse ruxolitinib affects response to substance ISO JAK2 (Homo sapiens) 6480464 JAK2 gene mutant form affects the susceptibility to ruxolitinib CTD PMID:26300391 Jak2 Mouse ruxolitinib multiple interactions ISO JAK2 (Homo sapiens) 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in decreased phosphorylation of JAK2 protein CTD PMID:30012499 Jak2 Mouse ruxolitinib decreases activity ISO JAK2 (Homo sapiens) 6480464 ruxolitinib results in decreased activity of JAK2 protein CTD PMID:24883332 and PMID:26300391 Jak2 Mouse S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression EXP 6480464 Buthionine Sulfoximine results in decreased expression of JAK2 mRNA CTD PMID:15878706 Jak2 Mouse S3I-201 multiple interactions ISO JAK2 (Homo sapiens) 149735343 S3I-201 inhibits the reaction [Rapamycin increases phosphorylation of JAK2 protein in lung epithelium] RGD Jak2 Mouse Salinomycin multiple interactions ISO JAK2 (Homo sapiens) 6480464 salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK2 protein] CTD PMID:32822738 Jak2 Mouse selumetinib increases phosphorylation ISO JAK2 (Homo sapiens) 127285668 selumetinib increases phosphorylation of JAK2 protein in colonic epithelium RGD Jak2 Mouse silibinin multiple interactions ISO JAK2 (Homo sapiens) 149735360 silibinin decreases expression and phosphorylation of JAK2 protein in breast epithelium RGD Jak2 Mouse silicon dioxide decreases expression ISO JAK2 (Homo sapiens) 6480464 Silicon Dioxide results in decreased expression of JAK2 mRNA CTD PMID:25351596 Jak2 Mouse silicon dioxide multiple interactions ISO JAK2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein] more ... CTD PMID:29894800 Jak2 Mouse silicon dioxide increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Silicon Dioxide results in increased phosphorylation of JAK2 protein CTD PMID:29894800 Jak2 Mouse simvastatin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]] more ... CTD PMID:16534557 more ... Jak2 Mouse simvastatin decreases phosphorylation ISO Jak2 (Rattus norvegicus) 6480464 Simvastatin results in decreased phosphorylation of JAK2 protein CTD PMID:18400235 Jak2 Mouse simvastatin decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Simvastatin results in decreased expression of JAK2 mRNA CTD PMID:16414398 Jak2 Mouse Sinomenine decreases phosphorylation ISO Jak2 (Rattus norvegicus) 149735350 Sinomenine decreases phosphorylation of Jak2 protein in lumber vertebra RGD Jak2 Mouse sodium arsenite multiple interactions ISO JAK2 (Homo sapiens) 6480464 Lapatinib inhibits the reaction [sodium arsenite results in increased phosphorylation of JAK2 protein] more ... CTD PMID:15116095 more ... Jak2 Mouse sodium arsenite increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of JAK2 protein CTD PMID:32890875 Jak2 Mouse sodium arsenite increases expression ISO JAK2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of JAK2 mRNA CTD PMID:28444938 Jak2 Mouse sphingosine 1-phosphate increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 sphingosine 1-phosphate results in increased phosphorylation of JAK2 protein CTD PMID:32401414 Jak2 Mouse spironolactone multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 Jak2 Mouse stattic multiple interactions EXP 6480464 stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA] and stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] CTD PMID:22454431 Jak2 Mouse streptozocin multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 mRNA] more ... CTD PMID:34391751 and PMID:36650709 Jak2 Mouse streptozocin increases expression ISO Jak2 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of JAK2 mRNA and Streptozocin results in increased expression of JAK2 protein CTD PMID:36650709 Jak2 Mouse succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of JAK2 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of JAK2 mRNA CTD PMID:21641980 and PMID:26378955 Jak2 Mouse sulfadimethoxine decreases expression ISO Jak2 (Rattus norvegicus) 6480464 Sulfadimethoxine results in decreased expression of JAK2 mRNA CTD PMID:30047161 Jak2 Mouse sulfasalazine multiple interactions EXP 6480464 Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein] CTD PMID:32272095 Jak2 Mouse sulforaphane multiple interactions EXP 6480464 sulforaphane inhibits the reaction [Cyclosporine results in increased phosphorylation of JAK2 protein] CTD PMID:23958496 Jak2 Mouse sunitinib decreases expression ISO JAK2 (Homo sapiens) 6480464 Sunitinib results in decreased expression of JAK2 mRNA CTD PMID:31533062 Jak2 Mouse T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of JAK2 mRNA CTD PMID:22454431 Jak2 Mouse T-2 toxin decreases expression ISO JAK2 (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of JAK2 mRNA CTD PMID:34581912 Jak2 Mouse T-2 toxin multiple interactions EXP 6480464 alpha-cyano-(3 more ... CTD PMID:22454431 Jak2 Mouse tacrolimus hydrate increases phosphorylation EXP 6480464 Tacrolimus results in increased phosphorylation of JAK2 protein CTD PMID:23958496 Jak2 Mouse tert-butyl hydroperoxide decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased phosphorylation of JAK2 protein CTD PMID:29128606 Jak2 Mouse tert-butyl hydroperoxide multiple interactions ISO JAK2 (Homo sapiens) 6480464 3 and 4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of JAK2 protein] CTD PMID:29128606 Jak2 Mouse testosterone enanthate increases expression ISO Jak2 (Rattus norvegicus) 6480464 testosterone enanthate results in increased expression of JAK2 mRNA CTD PMID:25603467 Jak2 Mouse tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of JAK2 mRNA CTD PMID:17484886 Jak2 Mouse tetrachloromethane multiple interactions EXP 6480464 ganoderic acid A inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK2 protein] CTD PMID:34029542 Jak2 Mouse tetrachloromethane increases phosphorylation EXP 6480464 Carbon Tetrachloride results in increased phosphorylation of JAK2 protein CTD PMID:34029542 Jak2 Mouse theobromine multiple interactions ISO Jak2 (Rattus norvegicus) 127229954 [Theobromine co-treated with Theanine] inhibits the reaction [1 more ... RGD Jak2 Mouse thymoquinone decreases phosphorylation EXP 6480464 thymoquinone results in decreased phosphorylation of JAK2 protein CTD PMID:34605108 Jak2 Mouse thymoquinone multiple interactions ISO JAK2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] CTD PMID:34627931 Jak2 Mouse thymoquinone decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 thymoquinone results in decreased phosphorylation of JAK2 protein CTD PMID:34627931 Jak2 Mouse thymoquinone multiple interactions EXP 6480464 Doxorubicin promotes the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein] and thymoquinone inhibits the reaction [Doxorubicin results in increased phosphorylation of JAK2 protein] CTD PMID:34605108 Jak2 Mouse Tiron multiple interactions ISO JAK2 (Homo sapiens) 6480464 1 more ... CTD PMID:15677497 Jak2 Mouse titanium dioxide decreases methylation EXP 6480464 titanium dioxide results in decreased methylation of JAK2 promoter CTD PMID:35295148 Jak2 Mouse tofacitinib affects response to substance ISO JAK2 (Homo sapiens) 6480464 JAK2 gene mutant form affects the susceptibility to tofacitinib CTD PMID:26300391 Jak2 Mouse tofacitinib multiple interactions ISO JAK2 (Homo sapiens) 6480464 tofacitinib inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein] more ... CTD PMID:21548952 more ... Jak2 Mouse tofacitinib decreases activity ISO JAK2 (Homo sapiens) 6480464 tofacitinib results in decreased activity of JAK2 protein CTD PMID:26300391 Jak2 Mouse toosendanin decreases phosphorylation ISO JAK2 (Homo sapiens) 6480464 toosendanin results in decreased phosphorylation of JAK2 protein CTD PMID:38460807 Jak2 Mouse toosendanin multiple interactions ISO JAK2 (Homo sapiens) 6480464 IL6 protein inhibits the reaction [toosendanin results in decreased phosphorylation of JAK2 protein] CTD PMID:38460807 Jak2 Mouse trichloroethene multiple interactions ISO JAK2 (Homo sapiens) 6480464 11-(2-pyrrolidin-1-ylethoxy)-14 more ... CTD PMID:34233590 Jak2 Mouse trichloroethene increases phosphorylation ISO JAK2 (Homo sapiens) 6480464 Trichloroethylene results in increased phosphorylation of JAK2 protein CTD PMID:34233590 Jak2 Mouse trichostatin A multiple interactions ISO JAK2 (Homo sapiens) 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of JAK2 mRNA] CTD PMID:14575637 Jak2 Mouse Triptolide multiple interactions ISO JAK2 (Homo sapiens) 6480464 triptolide results in decreased expression of and results in decreased phosphorylation of JAK2 protein CTD PMID:38115356 Jak2 Mouse triptonide decreases expression EXP 6480464 triptonide results in decreased expression of JAK2 mRNA CTD PMID:33045310 Jak2 Mouse troglitazone increases expression EXP 6480464 Troglitazone results in increased expression of JAK2 mRNA CTD PMID:31294483 Jak2 Mouse tropisetron multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 methyllycaconitine inhibits the reaction [Tropisetron inhibits the reaction [3-nitropropionic acid results in increased phosphorylation of JAK2 protein]] and Tropisetron inhibits the reaction [3-nitropropionic acid results in increased phosphorylation of JAK2 protein] CTD PMID:38513929 Jak2 Mouse tyrphostin B42 multiple interactions EXP 149735351 tyrphostin B42 inhibits the reaction [cisplatin increases expression of Jak2 mRNA in kidney] RGD Jak2 Mouse tyrphostin B42 multiple interactions ISO JAK2 (Homo sapiens) 127284886 tyrphostin B42 co-treated with N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases phosphorylation of JAK2 protein in stomach] RGD Jak2 Mouse tyrphostin B42 decreases expression EXP 18337263 Turphostin B42 decreased expression of Jak2 mRNA in myofibroblasts RGD Jak2 Mouse tyrphostin B42 multiple interactions ISO JAK2 (Homo sapiens) 127285668 tyrphostin B42 inhibits the reaction [selumetinib increases phosphorylation of JAK2 protein in colonic epithelium] RGD Jak2 Mouse tyrphostin B42 multiple interactions ISO JAK2 (Homo sapiens) 127285665 tyrphostin B42 decreases expression and phosphorylation of JAK2 protein in colonic epithelium RGD Jak2 Mouse umbelliferone multiple interactions ISO Jak2 (Rattus norvegicus) 6480464 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 mRNA] and 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 protein] CTD PMID:36650709 Jak2 Mouse urethane multiple interactions EXP 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of JAK2 mRNA CTD PMID:12400877 Jak2 Mouse urethane increases expression ISO JAK2 (Homo sapiens) 6480464 Urethane results in increased expression of JAK2 mRNA CTD PMID:28818685 Jak2 Mouse urethane increases expression EXP 6480464 Urethane results in increased expression of JAK2 mRNA CTD PMID:12400877 Jak2 Mouse valproic acid increases expression ISO JAK2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of JAK2 mRNA CTD PMID:29154799 Jak2 Mouse valproic acid decreases expression ISO JAK2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of JAK2 mRNA CTD PMID:25716160 Jak2 Mouse valproic acid increases methylation ISO JAK2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of JAK2 gene CTD PMID:29154799 Jak2 Mouse valsartan multiple interactions ISO JAK2 (Homo sapiens) 6480464 Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 Jak2 Mouse verteporfin multiple interactions EXP 6480464 [Verteporfin co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in decreased expression of JAK2 protein CTD PMID:31812773 Jak2 Mouse verteporfin decreases expression EXP 6480464 Verteporfin results in decreased expression of JAK2 protein CTD PMID:31812773 Jak2 Mouse vinclozolin increases expression ISO Jak2 (Rattus norvegicus) 6480464 vinclozolin results in increased expression of JAK2 mRNA CTD PMID:23555832 Jak2 Mouse zidovudine multiple interactions ISO JAK2 (Homo sapiens) 6480464 [Zidovudine co-treated with IFNA1 protein] results in increased expression of JAK2 mRNA CTD PMID:20370541 Jak2 Mouse zoledronic acid increases expression ISO JAK2 (Homo sapiens) 6480464 zoledronic acid results in increased expression of JAK2 mRNA CTD PMID:24714768