Jak2 (Janus kinase 2) - Rat Genome Database

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Gene: Jak2 (Janus kinase 2) Mus musculus
Analyze
Symbol: Jak2
Name: Janus kinase 2
RGD ID: 10823
MGI Page MGI
Description: Enables interleukin-12 receptor binding activity and protein tyrosine kinase activity. Involved in several processes, including hemopoiesis; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including cell surface receptor signaling pathway; cellular response to lipid; and regulation of apoptotic process. Located in caveola and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver and biliary system; and musculoskeletal system. Used to study essential thrombocythemia; myelofibrosis; myeloproliferative neoplasm; and polycythemia vera. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); hepatic vascular disease (multiple); inflammatory bowel disease (multiple); and lung non-small cell carcinoma (multiple). Orthologous to human JAK2 (Janus kinase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI504024; C81284; Fd17; JAK-2; tyrosine-protein kinase JAK2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,229,006 - 29,290,495 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,229,228 - 29,290,480 (+)EnsemblGRCm39 Ensembl
GRCm381929,251,803 - 29,313,095 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,251,828 - 29,313,080 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,326,318 - 29,387,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361929,318,452 - 29,377,979 (+)NCBIMGSCv36mm8
Celera1930,028,576 - 30,089,642 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1923.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (IEP)
Acute Lymphoblastic Leukemia, with Lymphomatous Features  (ISO)
acute myeloid leukemia  (ISO)
adrenocortical carcinoma  (ISO)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (IMP)
anemia  (IMP)
ankylosing spondylitis  (ISO)
bacterial gastritis  (ISO)
Brain Injuries  (ISO)
Budd-Chiari syndrome  (ISO)
Cachexia  (IEP)
calcinosis  (ISO)
Cancer Pain  (ISO)
chromosome 9p deletion syndrome  (ISO)
chronic myelogenous leukemia, BCR-ABL1 positive  (ISO)
chronic myeloid leukemia  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (ISO)
colorectal carcinoma  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
Diabetic Nephropathies  (ISO)
esophageal carcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
essential thrombocythemia  (IAGP,ISO)
Experimental Arthritis  (IMP,ISO)
Experimental Autoimmune Encephalomyelitis  (IDA)
Experimental Colitis  (ISO)
Experimental Liver Cirrhosis  (IDA,ISO)
Experimental Liver Neoplasms  (ISO)
familial erythrocytosis 1  (ISO)
familial erythrocytosis 2  (IMP)
fatty liver disease  (IMP)
genetic disease  (ISO)
Genetic Predisposition to Disease  (ISO)
glucose intolerance  (IMP)
Growth Disorders  (ISO)
heart disease  (ISO)
heart valve disease  (ISO)
hepatocellular carcinoma  (IEP,IMP,ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hyperalgesia  (IMP,ISO)
hyperuricemia  (ISO)
Inflammation  (ISO)
Intestinal Reperfusion Injury  (ISO)
leukemia  (ISO)
limited scleroderma  (ISO)
liver cancer  (IEP,IMP)
liver cirrhosis  (IEP)
Liver Injury  (ISO)
Liver Reperfusion Injury  (ISO)
lung adenocarcinoma  (ISO)
lung carcinoma  (ISO)
lung non-small cell carcinoma  (ISO)
mesenteric vascular occlusion  (ISO)
myelofibrosis  (IAGP,ISO)
myeloid neoplasm  (ISO)
myeloproliferative neoplasm  (IAGP)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
nasopharynx carcinoma  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephrotic syndrome  (IMP)
Niemann-Pick disease type C1  (IDA)
non-alcoholic fatty liver disease  (ISO)
non-alcoholic steatohepatitis  (IMP)
obesity  (ISO)
polycythemia  (IMP,ISO)
polycythemia vera  (IAGP,ISO)
portal hypertension  (IMP)
Pregnancy Complications  (ISO)
primary biliary cholangitis  (ISO)
Primary Ovarian Failure  (ISO)
primary ovarian insufficiency  (ISO)
Prostatic Neoplasms  (ISO)
Reperfusion Injury  (IMP)
retinal detachment  (ISO)
rheumatoid arthritis  (IMP)
scrapie  (IEP)
Sepsis  (ISO)
Sepsis-Associated Encephalopathy  (ISO)
Spinal Cord Injuries  (ISO)
Splenomegaly  (ISO)
Spontaneous Abortions  (ISO)
stomach cancer  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (IMP)
Thrombocythemia 3  (ISO)
thrombocytosis  (IAGP,ISO)
Thromboembolism  (ISO)
thrombosis  (IAGP)
transient cerebral ischemia  (ISO)
ulcerative colitis  (ISO)
Uterine Cervical Neoplasms  (ISO)
Venous Thrombosis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-Arctigenin  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
(R)-mevalonic acid  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-ethoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-methyladenine  (ISO)
3-methylcholanthrene  (EXP)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxynon-2-enal  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
abamectin  (ISO)
acetamide  (ISO)
acetic acid  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
aldosterone  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
amlodipine  (ISO)
ammonium chloride  (ISO)
angiotensin II  (ISO)
antirheumatic drug  (ISO)
apocynin  (ISO)
arecoline  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
auranofin  (ISO)
Bardoxolone methyl  (EXP)
baricitinib  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-D-glucosamine  (ISO)
beta-Elemonic acid  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butyric acid  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (ISO)
calciol  (EXP)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (ISO)
ceruletide  (EXP)
chelerythrine  (ISO)
chloroquine  (ISO)
chlorpyrifos  (EXP)
Cirsimarin  (EXP)
cisplatin  (EXP,ISO)
clomiphene  (ISO)
clothianidin  (ISO)
clozapine  (ISO)
cocaine  (EXP)
coniferyl aldehyde  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
coumermycin A1  (EXP)
crocin-1  (ISO)
cucurbitacin I  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
dapagliflozin  (ISO)
daunorubicin  (ISO)
decabromodiphenyl ether  (ISO)
delphinidin  (ISO)
deoxynivalenol  (EXP)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (EXP,ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
divanadium pentaoxide  (ISO)
doxorubicin  (EXP,ISO)
emodin  (ISO)
eriocitrin  (ISO)
erlotinib hydrochloride  (ISO)
estrone  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
fraxetin  (ISO)
fructose  (ISO)
fulvestrant  (EXP,ISO)
furan  (ISO)
galaxolide  (ISO)
Ganoderic acid A  (EXP)
genistein  (ISO)
Ginkgoic acid  (ISO)
glucose  (ISO)
glutathione  (EXP)
Goe 6976  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
hesperetin  (ISO)
hesperidin  (ISO)
hexadecanoic acid  (ISO)
hexestrol  (ISO)
hispidulin  (ISO)
hydrogen peroxide  (EXP,ISO)
ivermectin  (ISO)
kainic acid  (ISO)
ketamine  (ISO)
L-arginine  (EXP)
lapatinib  (ISO)
limonin  (EXP)
linagliptin  (EXP,ISO)
lipopolysaccharide  (EXP)
losartan  (ISO)
LY294002  (EXP)
melittin  (ISO)
melphalan  (ISO)
mercury atom  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
mesalamine  (ISO)
mestranol  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
Methylthiouracil  (ISO)
mitoxantrone  (ISO)
N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitric oxide  (EXP)
okadaic acid  (ISO)
olanzapine  (ISO)
oleic acid  (ISO)
ozone  (EXP)
pantoprazole  (EXP)
paracetamol  (EXP)
paroxetine  (ISO)
PD123319  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylpropanolamine  (ISO)
PhIP  (ISO)
phosphane  (ISO)
phosphatidic acid  (EXP)
pipoxolan  (EXP)
pirinixic acid  (EXP)
platycodin D  (ISO)
ponatinib  (ISO)
Ponicidin  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propofol  (ISO)
pterostilbene  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
Rhynchophylline  (ISO)
rotenone  (ISO)
rutin  (ISO)
ruxolitinib  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
S3I-201  (ISO)
Salinomycin  (ISO)
selumetinib  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
Sinomenine  (ISO)
sodium arsenite  (ISO)
sphingosine 1-phosphate  (ISO)
spironolactone  (ISO)
stattic  (EXP)
streptozocin  (ISO)
succimer  (EXP)
sulfasalazine  (EXP)
sulforaphane  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP,ISO)
tacrolimus hydrate  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
theobromine  (ISO)
thymoquinone  (EXP,ISO)
Tiron  (ISO)
tofacitinib  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
tyrphostin B42  (EXP,ISO)
urethane  (EXP,ISO)
valproic acid  (ISO)
valsartan  (ISO)
verteporfin  (EXP)
vinclozolin  (ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  (IDA)
activation of Janus kinase activity  (IDA)
adaptive immune response  (IEA)
axon regeneration  (ISO)
cell differentiation  (IMP)
cellular response to dexamethasone stimulus  (IDA)
cellular response to interleukin-3  (IDA)
cellular response to lipopolysaccharide  (IDA)
chromatin organization  (IEA)
collagen-activated signaling pathway  (ISO)
cytokine-mediated signaling pathway  (IBA,IMP,ISO,TAS)
enzyme-linked receptor protein signaling pathway  (IDA)
erythrocyte differentiation  (IBA,IMP)
extrinsic apoptotic signaling pathway  (IDA)
G protein-coupled receptor signaling pathway  (ISO)
granulocyte-macrophage colony-stimulating factor signaling pathway  (ISO)
growth hormone receptor signaling pathway  (ISO)
growth hormone receptor signaling pathway via JAK-STAT  (IDA,IMP,ISO)
hormone-mediated signaling pathway  (ISO)
immune response  (NAS)
immune system process  (IEA)
innate immune response  (IEA)
interleukin-12-mediated signaling pathway  (ISO)
interleukin-3-mediated signaling pathway  (ISO)
interleukin-5-mediated signaling pathway  (ISO)
intracellular signal transduction  (IBA,IDA)
intrinsic apoptotic signaling pathway in response to oxidative stress  (ISO)
mammary gland epithelium development  (IMP)
microglial cell activation  (IGI)
mineralocorticoid receptor signaling pathway  (ISO)
modulation of chemical synaptic transmission  (ISO)
myeloid cell differentiation  (IMP)
negative regulation of apoptotic process  (IDA,ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of cell population proliferation  (IMP)
negative regulation of cell-cell adhesion  (ISO)
negative regulation of DNA binding  (IDA)
negative regulation of heart contraction  (ISO)
negative regulation of heart contraction  (ISO)
negative regulation of neuron apoptotic process  (ISO)
obsolete histone H3-Y41 phosphorylation  (ISO)
peptidyl-tyrosine phosphorylation  (IDA)
phosphorylation  (IEA)
platelet-derived growth factor receptor signaling pathway  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of apoptotic signaling pathway  (IMP)
positive regulation of cell activation  (ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cell-substrate adhesion  (ISO)
positive regulation of cold-induced thermogenesis  (IMP)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of DNA binding  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of epithelial cell apoptotic process  (ISO)
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation  (ISO)
positive regulation of growth hormone receptor signaling pathway  (IMP)
positive regulation of inflammatory response  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of insulin secretion  (ISO)
positive regulation of interleukin-1 beta production  (IGI,ISO)
positive regulation of interleukin-17 production  (NAS)
positive regulation of leukocyte proliferation  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of MHC class II biosynthetic process  (IGI)
positive regulation of natural killer cell proliferation  (ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase biosynthetic process  (IDA,IGI,ISO)
positive regulation of NK T cell proliferation  (ISO,NAS)
positive regulation of peptidyl-tyrosine phosphorylation  (IMP)
positive regulation of phosphatidylinositol 3-kinase signaling  (IMP)
positive regulation of phosphoprotein phosphatase activity  (ISO)
positive regulation of platelet activation  (ISO)
positive regulation of platelet aggregation  (ISO)
positive regulation of platelet aggregation  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (ISO)
positive regulation of signaling receptor activity  (IGI)
positive regulation of SMAD protein signal transduction  (ISO)
positive regulation of T cell proliferation  (IDA,ISO)
positive regulation of T-helper 17 type immune response  (NAS)
positive regulation of transcription by RNA polymerase II  (IGI)
positive regulation of tumor necrosis factor production  (IDA,IGI)
positive regulation of type II interferon production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (IDA)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
post-embryonic hemopoiesis  (IMP)
post-translational protein modification  (ISO)
programmed cell death induced by symbiont  (IDA)
protein autophosphorylation  (IDA,ISO)
protein phosphorylation  (ISO)
receptor signaling pathway via JAK-STAT  (IBA,IDA,IGI,IMP,ISO)
regulation of inflammatory response  (ISO)
regulation of inflammatory response  (ISO)
regulation of nitric oxide biosynthetic process  (ISO)
regulation of postsynapse to nucleus signaling pathway  (ISO)
response to amine  (ISO)
response to antibiotic  (ISO)
response to antibiotic  (ISO)
response to granulocyte macrophage colony-stimulating factor  (NAS)
response to hydroperoxide  (ISO)
response to interleukin-12  (ISO)
response to lipopolysaccharide  (IDA)
response to organic cyclic compound  (ISO)
response to oxidative stress  (ISO)
response to tumor necrosis factor  (ISO)
signal transduction  (IMP)
transcription by RNA polymerase II  (IGI)
tumor necrosis factor-mediated signaling pathway  (ISO)
type II interferon-mediated signaling pathway  (ISO)
tyrosine phosphorylation of STAT protein  (IDA,IMP,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood coagulation  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal bone marrow cavity morphology  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal cell differentiation  (IAGP)
abnormal cell physiology  (IAGP)
abnormal common myeloid progenitor cell morphology  (IAGP)
abnormal cytokine level  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal embryonic erythropoiesis  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal granulocyte differentiation  (IAGP)
abnormal hematopoietic system physiology  (IAGP)
abnormal iron homeostasis  (IAGP)
abnormal mammary gland development  (IAGP)
abnormal mammary gland growth during lactation  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal megakaryocyte differentiation  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal protein level  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal spleen red pulp morphology  (IAGP)
abnormal spleen white pulp morphology  (IAGP)
abnormal thrombosis  (IAGP)
absent common myeloid progenitor cells  (IAGP)
anemia  (IAGP)
anisocytosis  (IAGP)
decreased B cell number  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating iron level  (IAGP)
decreased circulating luteinizing hormone level  (IAGP)
decreased corpora lutea number  (IAGP)
decreased embryo size  (IAGP)
decreased erythroblast number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased hematocrit  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased hemoglobin content  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased litter size  (IAGP)
decreased mean corpuscular hemoglobin  (IAGP)
decreased mean corpuscular volume  (IAGP)
decreased ovary weight  (IAGP)
decreased ovulation rate  (IAGP)
decreased spleen white pulp amount  (IAGP)
delayed estrous cycle  (IAGP)
delayed female fertility  (IAGP)
delayed sexual maturation  (IAGP)
delayed vaginal opening  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enhanced megakaryocyte emperipolesis  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
giant platelets  (IAGP)
hypochromic microcytic anemia  (IAGP)
impaired hematopoiesis  (IAGP)
increased chronic myelocytic leukemia incidence  (IAGP)
increased erythrocyte cell number  (IAGP)
increased erythroid progenitor cell number  (IAGP)
increased granulocyte number  (IAGP)
increased heart rate  (IAGP)
increased hematocrit  (IAGP)
increased hematopoietic stem cell number  (IAGP)
increased hemoglobin content  (IAGP)
increased hemolymphoid system tumor incidence  (IAGP)
increased leukocyte cell number  (IAGP)
increased lymphocyte cell number  (IAGP)
increased mean platelet volume  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased megakaryocyte progenitor cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen weight  (IAGP)
lactation failure  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
limb paralysis  (IAGP)
microcytosis  (IAGP)
myelofibrosis  (IAGP)
myeloid hyperplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
pallor  (IAGP)
poikilocytosis  (IAGP)
polychromatophilia  (IAGP)
polycythemia  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prolonged diestrus  (IAGP)
prolonged metestrus  (IAGP)
reduced female fertility  (IAGP)
reticulocytosis  (IAGP)
short proestrus  (IAGP)
small liver  (IAGP)
spleen fibrosis  (IAGP)
tachypnea  (IAGP)
thrombocytosis  (IAGP)
References

References - curated
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69. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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109. SMND-309, a novel derivative of salvianolic acid B, protects rat brains ischemia and reperfusion injury by targeting the JAK2/STAT3 pathway. Zhu H, etal., Eur J Pharmacol. 2013 Aug 15;714(1-3):23-31. doi: 10.1016/j.ejphar.2013.05.043. Epub 2013 Jun 11.
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PMID:15358195   PMID:15475610   PMID:15522878   PMID:15640156   PMID:15659653   PMID:15677447   PMID:15688008   PMID:15705783   PMID:15746188   PMID:15790774   PMID:15815685   PMID:15899943  
PMID:15923602   PMID:15988755   PMID:16025117   PMID:16084495   PMID:16141072   PMID:16141073   PMID:16230418   PMID:16254141   PMID:16280321   PMID:16365288   PMID:16478879   PMID:16482511  
PMID:16563502   PMID:16602821   PMID:16670266   PMID:16705159   PMID:16705160   PMID:16804112   PMID:16824542   PMID:16847321   PMID:16887119   PMID:16914724   PMID:16959875   PMID:17024180  
PMID:17078929   PMID:17128263   PMID:17183644   PMID:17290288   PMID:17317861   PMID:17404288   PMID:17519353   PMID:17543594   PMID:17547694   PMID:17550976   PMID:17726017   PMID:17728251  
PMID:17761766   PMID:17981124   PMID:18033315   PMID:18158285   PMID:18160720   PMID:18216297   PMID:18216868   PMID:18239084   PMID:18326042   PMID:18424709   PMID:18430728   PMID:18464116  
PMID:18480424   PMID:18485152   PMID:18499741   PMID:18515659   PMID:18636744   PMID:18653779   PMID:18682290   PMID:18692472   PMID:18718905   PMID:18835816   PMID:18854310   PMID:19075017  
PMID:19088061   PMID:19103753   PMID:19234114   PMID:19250698   PMID:19261614   PMID:19281795   PMID:19287004   PMID:19289461   PMID:19293402   PMID:19318353   PMID:19341767   PMID:19361784  
PMID:19494234   PMID:19500160   PMID:19508864   PMID:19538478   PMID:19571317   PMID:19638583   PMID:19638629   PMID:19789710   PMID:19835845   PMID:19884384   PMID:19887489   PMID:19888448  
PMID:20028972   PMID:20068132   PMID:20197548   PMID:20231889   PMID:20304997   PMID:20360640   PMID:20363735   PMID:20372968   PMID:20425335   PMID:20472827   PMID:20489053   PMID:20530874  
PMID:20541703   PMID:20568122   PMID:20592027   PMID:20639901   PMID:20663870   PMID:20669261   PMID:20696946   PMID:20724918   PMID:20940045   PMID:20974963   PMID:20979137   PMID:21102457  
PMID:21149549   PMID:21151131   PMID:21209203   PMID:21255641   PMID:21264353   PMID:21267068   PMID:21268070   PMID:21347402   PMID:21354995   PMID:21362419   PMID:21364286   PMID:21393331  
PMID:21420414   PMID:21423214   PMID:21557940   PMID:21572044   PMID:21606371   PMID:21633967   PMID:21726629   PMID:21802163   PMID:21808064   PMID:21860020   PMID:21873635   PMID:21885612  
PMID:21941370   PMID:22051730   PMID:22065597   PMID:22124464   PMID:22131881   PMID:22144185   PMID:22234689   PMID:22281400   PMID:22286129   PMID:22369852   PMID:22371173   PMID:22378845  
PMID:22384256   PMID:22402124   PMID:22508938   PMID:22546852   PMID:22627765   PMID:22740348   PMID:22837531   PMID:22892029   PMID:22972935   PMID:22999860   PMID:22999939   PMID:23047097  
PMID:23238822   PMID:23264594   PMID:23300995   PMID:23340136   PMID:23389690   PMID:23407880   PMID:23435120   PMID:23454976   PMID:23487027   PMID:23502961   PMID:23502962   PMID:23526587  
PMID:23533276   PMID:23544085   PMID:23548897   PMID:23558526   PMID:23581279   PMID:23590807   PMID:23630962   PMID:23747947   PMID:23750118   PMID:23782652   PMID:23831231   PMID:23838182  
PMID:23863895   PMID:23926298   PMID:23990909   PMID:24013029   PMID:24069548   PMID:24085768   PMID:24086539   PMID:24169825   PMID:24211109   PMID:24237791   PMID:24398427   PMID:24469804  
PMID:24480985   PMID:24486434   PMID:24531222   PMID:24562791   PMID:24608040   PMID:24648112   PMID:24677703   PMID:24692758   PMID:24791858   PMID:24802098   PMID:24859004   PMID:24920845  
PMID:24923444   PMID:24948418   PMID:24951423   PMID:25057888   PMID:25115888   PMID:25217696   PMID:25275304   PMID:25281607   PMID:25288396   PMID:25339357   PMID:25380525   PMID:25516983  
PMID:25552701   PMID:25572172   PMID:25582888   PMID:25595737   PMID:25644777   PMID:25793528   PMID:25969154   PMID:25977345   PMID:26044284   PMID:26092726   PMID:26175413   PMID:26227742  
PMID:26318719   PMID:26458983   PMID:26475415   PMID:26515423   PMID:26526549   PMID:26575024   PMID:26589916   PMID:26650570   PMID:26692333   PMID:26859362   PMID:26864339   PMID:27053299  
PMID:27081096   PMID:27096320   PMID:27154187   PMID:27222478   PMID:27261558   PMID:27288519   PMID:27383175   PMID:27401344   PMID:27406745   PMID:27713471   PMID:27905037   PMID:27998743  
PMID:27998978   PMID:28038963   PMID:28094236   PMID:28194444   PMID:28278176   PMID:28278513   PMID:28290604   PMID:28334068   PMID:28339658   PMID:28383049   PMID:28424277   PMID:28529954  
PMID:28538171   PMID:28611190   PMID:28615348   PMID:28637665   PMID:28668884   PMID:28724798   PMID:28728747   PMID:28744010   PMID:28794431   PMID:28810537   PMID:28849106   PMID:28880262  
PMID:28965767   PMID:29063123   PMID:29202466   PMID:29203511   PMID:29242197   PMID:29249691   PMID:29355841   PMID:29382747   PMID:29467301   PMID:29567773   PMID:29643232   PMID:29650953  
PMID:29673861   PMID:29688375   PMID:29749399   PMID:29751177   PMID:29907650   PMID:29959151   PMID:29971943   PMID:29991556   PMID:29992755   PMID:30024857   PMID:30171023   PMID:30242073  
PMID:30259280   PMID:30366920   PMID:30423295   PMID:30526368   PMID:30529759   PMID:30571460   PMID:30592974   PMID:30635286   PMID:30651633   PMID:30662340   PMID:30671064   PMID:30755420  
PMID:30801958   PMID:31255914   PMID:31346084   PMID:31467060   PMID:31467427   PMID:31545956   PMID:31679624   PMID:31697834   PMID:31712941   PMID:31732720   PMID:31865052   PMID:31886826  
PMID:31894268   PMID:31943454   PMID:32017785   PMID:32045363   PMID:32045382   PMID:32319222   PMID:32325033   PMID:32479500   PMID:32753471   PMID:32920974   PMID:32968282   PMID:33015166  
PMID:33041864   PMID:33075130   PMID:33144092   PMID:33314622   PMID:33378042   PMID:33567809   PMID:33667305   PMID:33682794   PMID:33754049   PMID:33770504   PMID:33811972   PMID:33907855  
PMID:34075160   PMID:34139651   PMID:34232994   PMID:34334085   PMID:34342643   PMID:34360789   PMID:34586888   PMID:34663512   PMID:34695437   PMID:34725437   PMID:34808021   PMID:34847985  
PMID:35011611   PMID:35016033   PMID:35156727   PMID:35169231   PMID:35216377   PMID:35365653   PMID:35382859   PMID:35421216   PMID:35439167   PMID:35493520   PMID:35598702   PMID:35902588  
PMID:36100596   PMID:36100613   PMID:36211444   PMID:36329047   PMID:36368558  


Genomics

Comparative Map Data
Jak2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,229,006 - 29,290,495 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,229,228 - 29,290,480 (+)EnsemblGRCm39 Ensembl
GRCm381929,251,803 - 29,313,095 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,251,828 - 29,313,080 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,326,318 - 29,387,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361929,318,452 - 29,377,979 (+)NCBIMGSCv36mm8
Celera1930,028,576 - 30,089,642 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1923.73NCBI
JAK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3894,984,390 - 5,129,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl94,984,390 - 5,129,948 (+)EnsemblGRCh38hg38GRCh38
GRCh3794,984,390 - 5,129,948 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3694,975,245 - 5,117,995 (+)NCBINCBI36Build 36hg18NCBI36
Build 3494,975,244 - 5,117,995NCBI
Celera94,910,860 - 5,053,802 (+)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef94,940,783 - 5,083,727 (+)NCBIHuRef
CHM1_194,985,470 - 5,128,355 (+)NCBICHM1_1
T2T-CHM13v2.094,989,498 - 5,135,022 (+)NCBIT2T-CHM13v2.0
Jak2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21226,995,334 - 227,054,381 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,995,334 - 227,054,189 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,396,988 - 235,455,863 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01242,326,646 - 242,385,527 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01235,144,413 - 235,203,184 (+)NCBIRnor_WKY
Rnor_6.01247,398,667 - 247,457,521 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,398,598 - 247,458,509 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,646,160 - 254,706,478 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,915,995 - 232,974,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,080,017 - 233,138,786 (+)NCBI
Celera1224,147,256 - 224,206,104 (+)NCBICelera
Cytogenetic Map1q52NCBI
Jak2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554349,227,595 - 9,341,208 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554349,227,897 - 9,341,208 (+)NCBIChiLan1.0ChiLan1.0
JAK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.195,006,271 - 5,156,626 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl95,006,271 - 5,156,626 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v094,820,303 - 4,971,867 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
JAK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,321,055 - 93,438,898 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,142,635 - 93,435,997 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha193,730,062 - 93,844,204 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0193,940,875 - 93,989,640 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,877,224 - 93,990,814 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,507,891 - 93,622,032 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,232,417 - 93,346,624 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,996,654 - 94,110,963 (+)NCBIUU_Cfam_GSD_1.0
Jak2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947140,931,052 - 141,061,286 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936503110,963 - 241,867 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936503111,722 - 243,627 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,848,689 - 217,002,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,849,744 - 217,002,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,696,921 - 242,837,407 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JAK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11274,421,243 - 74,566,766 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1274,421,016 - 74,566,710 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603862,818,134 - 62,927,470 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jak2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247369,724,369 - 9,830,365 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247369,724,876 - 9,827,364 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir375mmu-miR-375-3pMirecordsexternal_infoNANA15806104
Mir375mmu-miR-375-3pOncomiRDBexternal_infoNANA20548334
Mir135a-2mmu-miR-135a-5pOncomiRDBexternal_infoNANA22310976
Mir135a-2mmu-miR-135a-5pOncomiRDBexternal_infoNANA19666866
Mir135a-1mmu-miR-135a-5pOncomiRDBexternal_infoNANA22310976
Mir135a-1mmu-miR-135a-5pOncomiRDBexternal_infoNANA19666866

Predicted Target Of
Summary Value
Count of predictions:754
Count of miRNA genes:253
Interacting mature miRNAs:288
Transcripts:ENSMUST00000025705, ENSMUST00000065796
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
1357596Tgct3_mtesticular germ cell tumor 3 (mouse)Not determined192198409132912719Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1302123Tlsr8_mthymic lymphoma suppressor region 8 (mouse)Not determined192513600242388916Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
1357568Tgct4_mtesticular germ cell tumor 4 (mouse)Not determined192777198535295381Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse

Markers in Region
L16956  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381929,311,873 - 29,311,969UniSTSGRCm38
MGSCv371929,386,363 - 29,386,459UniSTSGRCm37
Celera1930,088,435 - 30,088,531UniSTS
Cytogenetic Map19C1UniSTS
cM Map1924.0UniSTS
Whitehead/MRC_RH19295.31UniSTS
AI504024  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381929,311,990 - 29,312,080UniSTSGRCm38
MGSCv371929,386,480 - 29,386,570UniSTSGRCm37
Celera1930,088,552 - 30,088,642UniSTS
Cytogenetic Map19C1UniSTS
cM Map1924.0UniSTS
Whitehead/MRC_RH19293.6UniSTS
Jak2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371929,385,486 - 29,386,325UniSTSGRCm37
MGSCv371929,342,527 - 29,342,751UniSTSGRCm37
Celera1930,044,530 - 30,044,754UniSTS
Celera1930,087,557 - 30,088,397UniSTS
Cytogenetic Map19C1UniSTS
cM Map1924.0UniSTS
cM Map1924.0UniSTS
cM Map1924.0UniSTS
Jak2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381929,310,996 - 29,311,835UniSTSGRCm38
MGSCv371929,385,486 - 29,386,325UniSTSGRCm37
Celera1930,087,557 - 30,088,397UniSTS
Cytogenetic Map19C1UniSTS
cM Map1924.0UniSTS
Jak2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381929,268,037 - 29,268,261UniSTSGRCm38
MGSCv371929,342,527 - 29,342,751UniSTSGRCm37
Celera1930,044,530 - 30,044,754UniSTS
Cytogenetic Map19C1UniSTS
cM Map1924.0UniSTS
L16956  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381929,311,829 - 29,311,963UniSTSGRCm38
MGSCv371929,386,319 - 29,386,453UniSTSGRCm37
Celera1930,088,391 - 30,088,525UniSTS
Cytogenetic Map19C1UniSTS
Whitehead/MRC_RH19293.5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001048177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA756436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC119228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY157991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY785782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE981299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF019856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF730796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG068603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD363707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ046359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ056249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L16956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M33423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000025705   ⟹   ENSMUSP00000025705
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1929,229,228 - 29,290,480 (+)Ensembl
GRCm38.p6 Ensembl1929,251,828 - 29,313,080 (+)Ensembl
RefSeq Acc Id: ENSMUST00000065796   ⟹   ENSMUSP00000064394
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1929,229,228 - 29,290,480 (+)Ensembl
GRCm38.p6 Ensembl1929,251,828 - 29,313,080 (+)Ensembl
RefSeq Acc Id: ENSMUST00000236990   ⟹   ENSMUSP00000158405
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1929,229,239 - 29,273,091 (+)Ensembl
GRCm38.p6 Ensembl1929,251,839 - 29,295,691 (+)Ensembl
RefSeq Acc Id: ENSMUST00000238009   ⟹   ENSMUSP00000158242
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1929,229,841 - 29,289,740 (+)Ensembl
GRCm38.p6 Ensembl1929,252,441 - 29,312,340 (+)Ensembl
RefSeq Acc Id: NM_001048177   ⟹   NP_001041642
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,229,203 - 29,290,495 (+)NCBI
GRCm381929,251,803 - 29,313,095 (+)NCBI
MGSCv371929,326,318 - 29,387,570 (+)RGD
Celera1930,028,576 - 30,089,642 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_008413   ⟹   NP_032439
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,229,203 - 29,290,495 (+)NCBI
GRCm381929,251,803 - 29,313,095 (+)NCBI
MGSCv371929,326,318 - 29,387,570 (+)RGD
Celera1930,028,576 - 30,089,642 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006526713   ⟹   XP_006526776
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,229,194 - 29,290,466 (+)NCBI
GRCm381929,252,026 - 29,313,061 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006526714   ⟹   XP_006526777
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,257,950 - 29,290,466 (+)NCBI
GRCm381929,280,546 - 29,313,061 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006526715   ⟹   XP_006526778
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,229,006 - 29,271,272 (+)NCBI
GRCm381929,252,026 - 29,293,872 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011247155   ⟹   XP_011245457
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,235,551 - 29,290,466 (+)NCBI
GRCm381929,258,151 - 29,313,066 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318068   ⟹   XP_017173557
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,252,402 - 29,290,466 (+)NCBI
GRCm381929,275,002 - 29,313,061 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036161449   ⟹   XP_036017342
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391929,229,006 - 29,272,342 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032439   ⟸   NM_008413
- UniProtKB: Q7TQD0 (UniProtKB/Swiss-Prot),   Q62120 (UniProtKB/Swiss-Prot),   G5E852 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001041642   ⟸   NM_001048177
- UniProtKB: Q7TQD0 (UniProtKB/Swiss-Prot),   Q62120 (UniProtKB/Swiss-Prot),   G5E852 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006526778   ⟸   XM_006526715
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006526776   ⟸   XM_006526713
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006526777   ⟸   XM_006526714
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011245457   ⟸   XM_011247155
- Peptide Label: isoform X1
- UniProtKB: Q7TQD0 (UniProtKB/Swiss-Prot),   G5E852 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173557   ⟸   XM_017318068
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSMUSP00000064394   ⟸   ENSMUST00000065796
RefSeq Acc Id: ENSMUSP00000158405   ⟸   ENSMUST00000236990
RefSeq Acc Id: ENSMUSP00000158242   ⟸   ENSMUST00000238009
RefSeq Acc Id: ENSMUSP00000025705   ⟸   ENSMUST00000025705
RefSeq Acc Id: XP_036017342   ⟸   XM_036161449
- Peptide Labe