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Gene: JAK2 (Janus kinase 2) Chlorocebus sabaeus

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Symbol:

JAK2

Name:

Janus kinase 2

RGD ID:

18560363

Description:

ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); growth hormone receptor binding (ortholog); insulin receptor substrate binding (ortholog); INVOLVED IN activation of Janus kinase activity (ortholog); axon regeneration (ortholog); cell surface receptor signaling pathway via JAK-STAT (ortholog); PARTICIPATES IN aldosterone signaling pathway; altered Jak-Stat signaling pathway; angiotensin II signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); acute myeloid leukemia (ortholog); alcoholic liver cirrhosis (ortholog); FOUND IN euchromatin (ortholog); glutamatergic synapse (ortholog); postsynapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tyrosine-protein kinase JAK2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	JAK2 (Janus kinase 2)	NCBI	Ortholog
Mus musculus (house mouse):	Jak2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Jak2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Jak2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	JAK2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	JAK2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Jak2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	JAK2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Jak2 (Janus kinase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	74,421,243 - 74,566,766 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	74,421,016 - 74,566,710 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	62,818,134 - 62,927,470 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

acute myeloid leukemia (ISO)

alcoholic liver cirrhosis (ISO)

Alzheimer's disease (ISO)

anemia (ISO)

ankylosing spondylitis (ISO)

atherosclerosis (ISO)

bacterial gastritis (ISO)

Brain Injuries (ISO)

Budd-Chiari syndrome (ISO)

Cachexia (ISO)

calcinosis (ISO)

Cancer Pain (ISO)

chromosome 9p deletion syndrome (ISO)

colon adenocarcinoma (ISO)

colon cancer (ISO)

colorectal carcinoma (ISO)

COVID-19 (ISO)

Crohn's disease (ISO)

Diabetic Nephropathies (ISO)

esophageal carcinoma (ISO)

esophagus squamous cell carcinoma (ISO)

essential thrombocythemia (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Experimental Colitis (ISO)

Experimental Liver Cirrhosis (ISO)

Experimental Liver Neoplasms (ISO)

familial erythrocytosis 1 (ISO)

familial erythrocytosis 2 (ISO)

genetic disease (ISO)

Genetic Predisposition to Disease (ISO)

glucose intolerance (ISO)

Growth Disorders (ISO)

heart disease (ISO)

heart valve disease (ISO)

hepatocellular carcinoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Hereditary Neoplastic Syndromes (ISO)

Hyperalgesia (ISO)

hyperuricemia (ISO)

Inflammation (ISO)

Intestinal Reperfusion Injury (ISO)

leukemia (ISO)

limited scleroderma (ISO)

liver cancer (ISO)

liver cirrhosis (ISO)

Liver Injury (ISO)

Liver Reperfusion Injury (ISO)

lung adenocarcinoma (ISO)

lung carcinoma (ISO)

lung non-small cell carcinoma (ISO)

mesenteric vascular occlusion (ISO)

metabolic dysfunction-associated steatohepatitis (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

myelofibrosis (ISO)

myeloid neoplasm (ISO)

myeloproliferative neoplasm (ISO)

myocardial infarction (ISO)

Myocardial Ischemia (ISO)

Myocardial Reperfusion Injury (ISO)

nasopharynx carcinoma (ISO)

Neoplasm Metastasis (ISO)

Neoplastic Cell Transformation (ISO)

nephrotic syndrome (ISO)

Niemann-Pick disease type C1 (ISO)

obesity (ISO)

polycythemia (ISO)

polycythemia vera (ISO)

portal hypertension (ISO)

Pregnancy Complications (ISO)

primary biliary cholangitis (ISO)

primary ovarian insufficiency (ISO)

Prostatic Neoplasms (ISO)

Reperfusion Injury (ISO)

retinal detachment (ISO)

rheumatoid arthritis (ISO)

scrapie (ISO)

Sepsis (ISO)

Sepsis-Associated Encephalopathy (ISO)

Spinal Cord Injuries (ISO)

Splenomegaly (ISO)

Spontaneous Abortions (ISO)

steatotic liver disease (ISO)

stomach cancer (ISO)

Stroke (ISO)

systemic lupus erythematosus (ISO)

Thrombocythemia 3 (ISO)

thrombocytosis (ISO)

Thromboembolism (ISO)

thrombosis (ISO)

transient cerebral ischemia (ISO)

ulcerative colitis (ISO)

urinary bladder cancer (ISO)

Uterine Cervical Neoplasms (ISO)

Venous Thrombosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of Janus kinase activity (ISO)

axon regeneration (ISO)

cell adhesion (IEA)

cell differentiation (IEA)

cell surface receptor signaling pathway via JAK-STAT (IEA,ISO)

cellular response to dexamethasone stimulus (IEA)

cellular response to interleukin-3 (IEA)

cellular response to lipopolysaccharide (IEA)

chromatin organization (IEA)

chromatin remodeling (IEA)

collagen-activated signaling pathway (IEA)

cytokine-mediated signaling pathway (IEA)

defense response to symbiont (IEA)

enzyme-linked receptor protein signaling pathway (IEA)

erythrocyte differentiation (IEA)

erythropoietin-mediated signaling pathway (IEA)

extrinsic apoptotic signaling pathway (IEA)

granulocyte-macrophage colony-stimulating factor signaling pathway (IEA)

growth hormone receptor signaling pathway (IEA)

growth hormone receptor signaling pathway via JAK-STAT (IEA,ISO)

hormone-mediated signaling pathway (ISO)

interleukin-12-mediated signaling pathway (IEA)

interleukin-23-mediated signaling pathway (IEA)

interleukin-3-mediated signaling pathway (IEA)

interleukin-5-mediated signaling pathway (IEA)

intracellular signal transduction (IEA)

intrinsic apoptotic signaling pathway in response to oxidative stress (ISO)

lipopolysaccharide-mediated signaling pathway (IEA)

mammary gland epithelium development (IEA)

microglial cell activation (IEA)

modulation of chemical synaptic transmission (ISO)

myeloid cell differentiation (IEA)

negative regulation of apoptotic process (IEA,ISO)

negative regulation of cardiac muscle cell apoptotic process (ISO)

negative regulation of cell population proliferation (IEA)

negative regulation of cell-cell adhesion (ISO)

negative regulation of cytokine production involved in inflammatory response (IEA)

negative regulation of neuron apoptotic process (ISO)

nuclear receptor-mediated mineralocorticoid signaling pathway (ISO)

peptidyl-tyrosine phosphorylation (ISO)

platelet-derived growth factor receptor signaling pathway (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of apoptotic signaling pathway (IEA)

positive regulation of cell activation (ISO)

positive regulation of cell differentiation (ISO)

positive regulation of cell migration (ISO)

positive regulation of cell population proliferation (IEA,ISO)

positive regulation of cell-substrate adhesion (IEA)

positive regulation of cold-induced thermogenesis (IEA)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of DNA binding (ISO)

positive regulation of DNA-binding transcription factor activity (ISO)

positive regulation of epithelial cell apoptotic process (ISO)

positive regulation of growth factor dependent skeletal muscle satellite cell proliferation (ISO)

positive regulation of growth hormone receptor signaling pathway (IEA)

positive regulation of insulin secretion (ISO)

positive regulation of interleukin-1 beta production (IEA,ISO)

positive regulation of leukocyte proliferation (IEA)

positive regulation of MAPK cascade (ISO)

positive regulation of MHC class II biosynthetic process (IEA)

positive regulation of natural killer cell proliferation (IEA)

positive regulation of nitric oxide biosynthetic process (ISO)

positive regulation of NK T cell proliferation (IEA)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

positive regulation of platelet activation (IEA)

positive regulation of platelet aggregation (IEA)

positive regulation of protein import into nucleus (ISO)

positive regulation of receptor signaling pathway via JAK-STAT (IEA)

positive regulation of SMAD protein signal transduction (IEA)

positive regulation of T cell proliferation (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of tumor necrosis factor production (IEA,ISO)

positive regulation of type II interferon production (IEA)

positive regulation of tyrosine phosphorylation of STAT protein (ISO)

positive regulation of vascular associated smooth muscle cell proliferation (ISO)

post-embryonic hemopoiesis (IEA)

post-translational protein modification (IEA)

protein autophosphorylation (ISO)

regulation of apoptotic process (IEA)

regulation of cell activation (IEA)

regulation of cell-cell adhesion (IEA)

regulation of inflammatory response (IEA)

regulation of nitric oxide biosynthetic process (ISO)

regulation of postsynapse to nucleus signaling pathway (ISO)

response to antibiotic (IEA)

response to hydroperoxide (ISO)

response to interleukin-12 (IEA)

response to oxidative stress (ISO)

response to tumor necrosis factor (IEA)

signal transduction (IEA)

symbiont-induced defense-related programmed cell death (IEA)

thrombopoietin-mediated signaling pathway (IEA)

transcription by RNA polymerase II (IEA)

tumor necrosis factor-mediated signaling pathway (IEA)

type II interferon-mediated signaling pathway (ISO)

tyrosine phosphorylation of STAT protein (ISO)

Cellular Component

caveola (IEA)

cytoplasm (IEA)

cytoplasmic side of plasma membrane (IEA)

cytoskeleton (IEA)

cytosol (IEA)

endomembrane system (IEA)

euchromatin (ISO)

extrinsic component of cytoplasmic side of plasma membrane (IEA)

extrinsic component of plasma membrane (IEA)

focal adhesion (IEA)

glutamatergic synapse (ISO)

granulocyte macrophage colony-stimulating factor receptor complex (IEA)

interleukin-12 receptor complex (IEA)

interleukin-23 receptor complex (IEA)

membrane (IEA)

membrane raft (IEA)

nucleoplasm (IEA)

nucleus (IEA)

plasma membrane (IEA)

postsynapse (ISO)

Molecular Function

acetylcholine receptor binding (ISO)

ATP binding (IEA)

cytokine receptor binding (IEA)

growth hormone receptor binding (IEA,ISO)

heme binding (IEA)

histone binding (IEA)

histone H3Y41 kinase activity (IEA)

identical protein binding (IEA)

insulin receptor substrate binding (ISO)

interleukin-12 receptor binding (IEA)

kinase activity (IEA)

non-membrane spanning protein tyrosine kinase activity (IEA)

nucleotide binding (IEA)

peptide hormone receptor binding (ISO)

phosphatidylinositol 3-kinase binding (ISO)

protein binding (ISO)

protein kinase activity (IEA)

protein kinase binding (IEA)

protein tyrosine kinase activity (IEA,ISO)

SH2 domain binding (IEA)

signaling receptor activator activity (IEA)

signaling receptor binding (IEA)

transferase activity (IEA)

type 1 angiotensin receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

aldosterone signaling pathway (ISO)

altered Jak-Stat signaling pathway (ISO)

angiotensin II signaling pathway (ISO)

angiotensin II signaling pathway via AT1 receptor (ISO)

endothelin signaling pathway (ISO)

erythropoietin signaling pathway (ISO)

granulocyte-macrophage colony-stimulating factor signaling pathway (ISO)

growth hormone signaling pathway (ISO)

interleukin-12 signaling pathway (ISO)

interleukin-23 signaling pathway (ISO)

interleukin-27 signaling pathway (ISO)

interleukin-3 signaling pathway (ISO)

interleukin-4 signaling pathway (ISO)

interleukin-5 signaling pathway (ISO)

interleukin-6 signaling pathway (ISO)

Jak-Stat signaling pathway (ISO)

leptin system pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

somatostatin signaling pathway (ISO)

sphingosine 1-phosphate signaling pathway (ISO)

type II interferon signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

JAK2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	74,421,243 - 74,566,766 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	74,421,016 - 74,566,710 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	62,818,134 - 62,927,470 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JAK2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	4,984,390 - 5,129,948 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	4,984,390 - 5,129,948 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	4,984,390 - 5,129,948 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	4,975,245 - 5,117,995 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	4,975,244 - 5,117,995	NCBI
Celera	9	4,910,860 - 5,053,802 (+)	NCBI		Celera
Cytogenetic Map	9	p24.1	NCBI
HuRef	9	4,940,783 - 5,083,727 (+)	NCBI		HuRef
CHM1_1	9	4,985,470 - 5,128,355 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	4,989,498 - 5,135,022 (+)	NCBI		T2T-CHM13v2.0

Jak2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	29,229,006 - 29,290,495 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	29,229,228 - 29,290,480 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	29,251,803 - 29,313,095 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	29,251,828 - 29,313,080 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	29,326,318 - 29,387,570 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	29,318,452 - 29,377,979 (+)	NCBI		MGSCv36	mm8
Celera	19	30,028,576 - 30,089,642 (+)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	23.73	NCBI

Jak2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	236,408,905 - 236,468,769 (+)	NCBI		GRCr8
mRatBN7.2	1	226,995,334 - 227,054,381 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	226,995,334 - 227,054,189 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	235,396,988 - 235,455,863 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	242,326,646 - 242,385,527 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	235,144,413 - 235,203,184 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	247,398,667 - 247,457,521 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	247,398,598 - 247,458,509 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	254,646,160 - 254,706,478 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	232,915,995 - 232,974,763 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	233,080,017 - 233,138,786 (+)	NCBI
Celera	1	224,147,256 - 224,206,104 (+)	NCBI		Celera
Cytogenetic Map	1	q52	NCBI

Jak2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	9,227,595 - 9,341,208 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955434	9,227,897 - 9,341,208 (+)	NCBI	ChiLan1.0	ChiLan1.0

JAK2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	119,420,003 - 119,589,890 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	119,425,950 - 119,595,837 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	4,820,303 - 4,971,867 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	5,006,271 - 5,156,626 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	5,006,271 - 5,156,626 (+)	Ensembl	panpan1.1		panPan2

JAK2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	93,321,055 - 93,438,898 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	93,142,635 - 93,435,997 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	93,730,062 - 93,844,204 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	93,940,875 - 93,989,640 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	93,877,224 - 93,990,814 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	93,507,891 - 93,622,032 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	93,232,417 - 93,346,624 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	93,996,654 - 94,110,963 (+)	NCBI		UU_Cfam_GSD_1.0

Jak2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	140,931,052 - 141,061,286 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936503	110,963 - 241,867 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936503	111,722 - 243,627 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JAK2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	216,848,689 - 217,002,148 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	216,849,744 - 217,002,310 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	242,696,921 - 242,837,407 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Jak2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	9,724,369 - 9,830,365 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	9,724,876 - 9,827,364 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in JAK2
2242 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007969341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007969342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037998439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000006895 ⟹ ENSCSAP00000005088

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	12	74,421,016 - 74,566,710 (-)	Ensembl

RefSeq Acc Id:

XM_037998439 ⟹ XP_037854367

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666038	62,818,134 - 62,927,470 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_037854367	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000005088.1

Ensembl Acc Id:

ENSCSAP00000005088 ⟸ ENSCSAT00000006895

RefSeq Acc Id:	XP_037854367 ⟸ XM_037998439
- UniProtKB:	A0A0D9R8Z9 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000008828	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000006895.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
	3.30.505.10	UniProtKB/TrEMBL
	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Band_41_domain	UniProtKB/TrEMBL
	FERM_2	UniProtKB/TrEMBL
	FERM_central	UniProtKB/TrEMBL
	FERM_domain	UniProtKB/TrEMBL
	FERM_F1	UniProtKB/TrEMBL
	FERM_F2	UniProtKB/TrEMBL
	JAK	UniProtKB/TrEMBL
	Jak1_PHL_dom	UniProtKB/TrEMBL
	JAK2_FERM_C-lobe	UniProtKB/TrEMBL
	JAK2_SH2	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	PH-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	PTK_Jak2_rpt1	UniProtKB/TrEMBL
	PTKc_Jak2_rpt2	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/TrEMBL
	Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	Tyr_kinase_non-rcpt_Jak/Tyk2	UniProtKB/TrEMBL
	Tyr_kinase_non-rcpt_Jak2	UniProtKB/TrEMBL
KEGG Report	csab:103219496	UniProtKB/TrEMBL
NCBI Gene	JAK2	ENTREZGENE
PANTHER	TYROSINE-PROTEIN KINASE HOPSCOTCH	UniProtKB/TrEMBL
	TYROSINE-PROTEIN KINASE JAK2	UniProtKB/TrEMBL
Pfam	FERM_F1	UniProtKB/TrEMBL
	FERM_F2	UniProtKB/TrEMBL
	Jak1_Phl	UniProtKB/TrEMBL
	Pkinase_Tyr	UniProtKB/TrEMBL
	SH2_1	UniProtKB/TrEMBL
PIRSF	TyrPK_Jak	UniProtKB/TrEMBL
PRINTS	JANUSKINASE	UniProtKB/TrEMBL
	JANUSKINASE2	UniProtKB/TrEMBL
	TYRKINASE	UniProtKB/TrEMBL
PROSITE	FERM_3	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
SMART	B41	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	TyrKc	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF47031	UniProtKB/TrEMBL
	SSF55550	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A0D9R8Z9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)