Ghr (growth hormone receptor) - Rat Genome Database

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Gene: Ghr (growth hormone receptor) Rattus norvegicus
Analyze
Symbol: Ghr
Name: growth hormone receptor
RGD ID: 2687
Description: Enables SH2 domain binding activity; enzyme binding activity; and growth hormone receptor activity. Involved in several processes, including activation of Janus kinase activity; cellular response to hormone stimulus; and receptor signaling pathway via JAK-STAT. Located in several cellular components, including extracellular space; mitochondrion; and neuronal cell body. Biomarker of congenital hypothyroidism; muscular atrophy; osteopetrosis; and osteoporosis. Human ortholog(s) of this gene implicated in several diseases, including Laron syndrome; familial hypercholesterolemia; isolated growth hormone deficiency; osteoarthritis; and type 2 diabetes mellitus. Orthologous to human GHR (growth hormone receptor); PARTICIPATES IN growth hormone signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GH receptor; GHR/BP; growth hormone receptor precursor splice variant D56; growth hormone receptor variant d5-6; growth hormone receptor/binding protein; MGC124963; MGC156665; somatotropin receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2252,541,452 - 52,804,960 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl252,542,594 - 52,804,735 (-)Ensembl
Rnor_6.0253,149,225 - 53,413,954 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,150,370 - 53,413,638 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0272,265,571 - 72,346,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0272,182,692 - 72,218,250 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4252,496,517 - 52,658,066 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1252,424,749 - 52,586,299 (-)NCBI
Celera248,257,266 - 48,408,640 (-)NCBICelera
RH 3.4 Map2332.2RGD
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-vinylcyclohexene dioxide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
atrazine  (EXP)
bacitracin  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
calcitriol  (EXP)
calcium atom  (EXP)
calcium(0)  (EXP)
capsaicin  (EXP)
carbon nanotube  (ISO)
chlormequat chloride  (EXP)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
cytarabine  (ISO)
DDT  (EXP)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
dichlorine  (EXP)
diclofenac  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP,ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
menadione  (ISO)
methapyrilene  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mifepristone  (EXP)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (EXP,ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
naproxen  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
permethrin  (EXP)
phenethyl caffeate  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (EXP)
propiconazole  (ISO)
raloxifene  (ISO)
resveratrol  (EXP,ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
streptozocin  (EXP)
sulindac  (EXP)
sumatriptan  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Audi L, etal., J Clin Endocrinol Metab. 2006 Dec;91(12):5038-43. Epub 2006 Sep 26.
2. Bellush LL, etal., Endocrinology. 2000 Jan;141(1):163-8.
3. Bennett WL, etal., Endocrine. 2007 Oct;32(2):219-26. Epub 2007 Nov 27.
4. Berger I, etal., Histol Histopathol. 2007 Nov;22(11):1231-9.
5. Bohm SA, etal., Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):185-8.
6. Casse AH, etal., Endocrinology. 2003 Aug;144(8):3692-7.
7. Chen S, etal., World J Gastroenterol. 2004 Oct 1;10(19):2894-7.
8. Christophidis LJ, etal., Growth Horm IGF Res. 2009 Dec;19(6):497-506. Epub 2009 Jun 12.
9. Claessen KM, etal., Ann Rheum Dis. 2014 Feb;73(2):433-6. doi: 10.1136/annrheumdis-2012-202713. Epub 2013 Jun 5.
10. Cruickshank J, etal., J Endocrinol. 2005 Mar;184(3):543-53.
11. Du L, etal., Endocrinology 2003 Mar;144(3):868-76.
12. Enhamre E, etal., Neurosci Lett. 2012 Aug 8;523(1):82-6. doi: 10.1016/j.neulet.2012.06.050. Epub 2012 Jun 27.
13. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
14. Gerland K, etal., Mol Cell Endocrinol. 2000 Oct 25;168(1-2):1-9.
15. Gevers EF, etal., J Bone Miner Res 2002 Aug;17(8):1408-19.
16. GOA data from the GO Consortium
17. Godowski PJ, etal., Proc Natl Acad Sci U S A. 1989 Oct;86(20):8083-7.
18. Gowri PM, etal., Mol Cell Biol. 2003 Feb;23(3):815-25.
19. Hartleb S, etal., Pharmacogenomics. 2011 Dec;12(12):1653-61. doi: 10.2217/pgs.11.113. Epub 2011 Oct 25.
20. Held MA, etal., Am J Physiol Gastrointest Liver Physiol. 2005 May;288(5):G986-93. Epub 2004 Dec 16.
21. Hellgren G, etal., J Interferon Cytokine Res. 2001 Feb;21(2):75-83.
22. Hull KL and Harvey S, Growth Horm IGF Res. 1998 Apr;8(2):167-73.
23. Jeay S, etal., Endocrinology 2001 Jan;142(1):147-56.
24. Klammt J, etal., Clin Endocrinol (Oxf). 2015 Mar;82(3):453-61. doi: 10.1111/cen.12606. Epub 2014 Oct 20.
25. Kobayashi K, etal., Endocr J. 1999 Mar;46 Suppl:S67-9.
26. Kong SE, etal., Am J Physiol Endocrinol Metab 2002 Oct;283(4):E692-701.
27. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
28. Landau D, etal., Growth Horm IGF Res. 1998 Feb;8(1):39-45.
29. Landau D, etal., Int J Exp Diabetes Res. 2000;1(1):9-18.
30. Li W, etal., Acta Pharmacol Sin. 2004 Apr;25(4):490-5.
31. Mathews LS, etal., J Biol Chem 1989 Jun 15;264(17):9905-10.
32. Menon RK, etal., J Endocrinol. 1994 Sep;142(3):453-62.
33. MGD data from the GO Consortium
34. Moderscheim TA, etal., Brain Res. 2007 Mar 16;1137(1):29-34. Epub 2006 Dec 20.
35. NCBI rat LocusLink and RefSeq merged data July 26, 2002
36. O'Leary MJ, etal., Crit Care. 2007;11(4):R79.
37. O'Leary MJ, etal., Intensive Care Med. 2000 Oct;26(10):1547-52.
38. OMIM Disease Annotation Pipeline
39. Online Mendelian Inheritance in Man, OMIM (TM).
40. Pazaitou-Panayiotou K, etal., Eur J Endocrinol. 2007 Feb;156(2):187-94.
41. Pereira FA, etal., Calcif Tissue Int. 2009 Jul;85(1):75-83. doi: 10.1007/s00223-009-9249-3. Epub 2009 May 8.
42. Perret-Vivancos C, etal., Exp Cell Res. 2006 Feb 1;312(3):215-32.
43. Pipeline to import KEGG annotations from KEGG into RGD
44. RGD automated data pipeline
45. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
46. RGD automated import pipeline for gene-chemical interactions
47. Sanchez JE, etal., J Clin Endocrinol Metab. 1998 Nov;83(11):4079-83.
48. Segev Y, etal., J Am Soc Nephrol. 1999 Nov;10(11):2374-81.
49. Sobrier ML, etal., J Clin Endocrinol Metab. 1997 Feb;82(2):435-7.
50. Stofega MR, etal., Mol Endocrinol. 2000 Sep;14(9):1338-50.
51. Strawbridge RJ, etal., Growth Horm IGF Res. 2007 Oct;17(5):392-8. Epub 2007 May 29.
52. Symons AL Eur J Oral Sci. 2003 Dec;111(6):503-9.
53. Tang H, etal., J Neurosci Res. 2011 Feb;89(2):248-55. doi: 10.1002/jnr.22540. Epub 2010 Dec 8.
54. Taylor WE, etal., J Gravit Physiol. 2002 Dec;9(2):61-70.
55. Thornwall-Le Greves M, etal., Neurosci Lett. 2001 May 18;304(1-2):69-72.
56. Valerio G, etal., Clin Endocrinol (Oxf). 1997 Sep;47(3):329-35.
57. van der Pluijm I, etal., PLoS Biol. 2007 Jan;5(1):e2.
58. VanderKuur JA, etal., J Biol Chem. 1994 Aug 26;269(34):21709-17.
59. Wang HT, etal., World J Gastroenterol. 2003 Apr;9(4):765-70.
60. Wang P, etal., Zhonghua Wai Ke Za Zhi. 2002 Dec;40(12):940-4.
61. Wassenaar MJ, etal., J Clin Endocrinol Metab. 2009 Dec;94(12):4671-8. doi: 10.1210/jc.2009-1172. Epub 2009 Oct 28.
62. Wolf N, etal., Exp Eye Res. 2005 Sep;81(3):276-85.
63. Zhao J, etal., Zygote 2002 Feb;10(1):85-94.
64. Zhou Y, etal., Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13215-20.
Additional References at PubMed
PMID:1446642   PMID:1549776   PMID:2792761   PMID:2825030   PMID:6303755   PMID:7545168   PMID:7565946   PMID:7615519   PMID:7835307   PMID:8137822   PMID:8702683   PMID:8921876  
PMID:8943276   PMID:9144201   PMID:9231797   PMID:9360546   PMID:9571026   PMID:10556780   PMID:10585430   PMID:11834450   PMID:12477932   PMID:12488452   PMID:12552091   PMID:15609625  
PMID:15664698   PMID:15763517   PMID:16116438   PMID:16154995   PMID:16867182   PMID:17088403   PMID:17090972   PMID:17658679   PMID:18648510   PMID:20814072   PMID:21177131   PMID:21195069  
PMID:22715380   PMID:24006456   PMID:24963636  


Genomics

Comparative Map Data
Ghr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2252,541,452 - 52,804,960 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl252,542,594 - 52,804,735 (-)Ensembl
Rnor_6.0253,149,225 - 53,413,954 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,150,370 - 53,413,638 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0272,265,571 - 72,346,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0272,182,692 - 72,218,250 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4252,496,517 - 52,658,066 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1252,424,749 - 52,586,299 (-)NCBI
Celera248,257,266 - 48,408,640 (-)NCBICelera
RH 3.4 Map2332.2RGD
Cytogenetic Map2q16NCBI
GHR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38542,423,439 - 42,721,878 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl542,423,439 - 42,721,878 (+)EnsemblGRCh38hg38GRCh38
GRCh37542,423,541 - 42,721,980 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36542,459,783 - 42,757,683 (+)NCBINCBI36hg18NCBI36
Build 34542,459,782 - 42,757,682NCBI
Celera542,314,115 - 42,611,474 (+)NCBI
Cytogenetic Map5p13.1-p12NCBI
HuRef542,375,464 - 42,673,429 (+)NCBIHuRef
CHM1_1542,425,901 - 42,723,964 (+)NCBICHM1_1
T2T-CHM13v2.0542,678,916 - 42,974,806 (+)NCBI
Ghr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,347,237 - 3,612,834 (-)NCBIGRCm39mm39
GRCm39 Ensembl153,347,242 - 3,612,974 (-)Ensembl
GRCm38153,317,755 - 3,583,352 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,317,760 - 3,583,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv37153,267,760 - 3,533,230 (-)NCBIGRCm37mm9NCBIm37
MGSCv36153,267,774 - 3,533,231 (-)NCBImm8
Celera153,182,321 - 3,448,882 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.84NCBI
Ghr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542626,689,581 - 26,871,684 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542626,553,509 - 26,873,619 (+)NCBIChiLan1.0ChiLan1.0
GHR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1572,700,150 - 72,997,356 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl572,700,150 - 72,871,278 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0567,654,326 - 67,953,140 (-)NCBIMhudiblu_PPA_v0panPan3
GHR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1467,021,821 - 67,245,499 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl467,022,252 - 67,290,473 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha466,705,544 - 66,845,096 (-)NCBI
ROS_Cfam_1.0467,531,090 - 67,802,322 (-)NCBI
ROS_Cfam_1.0 Ensembl467,532,966 - 67,802,335 (-)Ensembl
UMICH_Zoey_3.1467,276,975 - 67,416,597 (-)NCBI
UNSW_CanFamBas_1.0467,407,363 - 67,546,744 (-)NCBI
UU_Cfam_GSD_1.0467,943,814 - 68,083,513 (-)NCBI
Ghr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213230,991,608 - 231,135,845 (+)NCBI
SpeTri2.0NW_004936518235,996 - 380,225 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1627,126,286 - 27,422,268 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11627,126,300 - 27,422,618 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21628,691,739 - 28,855,136 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1441,171,038 - 41,464,474 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl441,285,712 - 41,464,666 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607131,608,844 - 31,907,481 (+)NCBIVero_WHO_p1.0
Ghr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475912,285,594 - 12,570,906 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475912,282,295 - 12,570,106 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D2Chm149  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2252,692,967 - 52,693,212 (+)MAPPERmRatBN7.2
Rnor_6.0253,302,376 - 53,302,618NCBIRnor6.0
Rnor_5.0272,334,610 - 72,334,852UniSTSRnor5.0
RGSC_v3.4252,646,559 - 52,646,801UniSTSRGSC3.4
Celera248,397,132 - 48,397,374UniSTS
Cytogenetic Map2q16UniSTS
RH142196  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2252,542,574 - 52,542,736 (+)MAPPERmRatBN7.2
Rnor_6.0253,150,351 - 53,150,512NCBIRnor6.0
Rnor_5.0272,182,673 - 72,182,834UniSTSRnor5.0
RGSC_v3.4252,496,498 - 52,496,659UniSTSRGSC3.4
Celera248,257,247 - 48,257,408UniSTS
RH 3.4 Map2332.2UniSTS
Cytogenetic Map2q16UniSTS
RH141289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2252,542,348 - 52,542,548 (+)MAPPERmRatBN7.2
Rnor_6.0253,150,125 - 53,150,324NCBIRnor6.0
Rnor_5.0272,182,447 - 72,182,646UniSTSRnor5.0
RGSC_v3.4252,496,272 - 52,496,471UniSTSRGSC3.4
Celera248,257,021 - 48,257,220UniSTS
RH 3.4 Map2330.5UniSTS
Cytogenetic Map2q16UniSTS
Ghr  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2252,551,768 - 52,552,167 (+)MAPPERmRatBN7.2
Rnor_6.0253,159,545 - 53,159,941NCBIRnor6.0
Rnor_5.0272,191,867 - 72,192,263UniSTSRnor5.0
RGSC_v3.4252,505,691 - 52,506,087UniSTSRGSC3.4
Celera248,266,438 - 48,266,834UniSTS
Cytogenetic Map2q16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
12879863Bp402Blood pressure QTL 4020.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24112578956532139Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)24280460760653831Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)243162366111362592Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:362
Count of miRNA genes:214
Interacting mature miRNAs:257
Transcripts:ENSRNOT00000021081, ENSRNOT00000046951
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 43 52 41 11 41 8 11 8 35 32 11 8
Low 1 5 8 66 9
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH006760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC103659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC161852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF330099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF412704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW395402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S49003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S76627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z83757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000021081   ⟹   ENSRNOP00000021081
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl252,551,639 - 52,804,735 (-)Ensembl
Rnor_6.0 Ensembl253,159,873 - 53,413,638 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000046951   ⟹   ENSRNOP00000044119
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl252,542,594 - 52,704,478 (-)Ensembl
Rnor_6.0 Ensembl253,150,370 - 53,313,884 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081558   ⟹   ENSRNOP00000072873
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl253,159,525 - 53,185,926 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088876   ⟹   ENSRNOP00000071833
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl252,543,435 - 52,804,735 (-)Ensembl
Rnor_6.0 Ensembl253,151,211 - 53,300,404 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096351   ⟹   ENSRNOP00000096274
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl252,542,594 - 52,704,478 (-)Ensembl
RefSeq Acc Id: NM_017094   ⟹   NP_058790
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2252,542,594 - 52,704,478 (-)NCBI
Rnor_6.0253,150,370 - 53,313,884 (-)NCBI
Rnor_5.0272,182,692 - 72,218,250 (-)NCBI
Rnor_5.0272,265,571 - 72,346,118 (-)NCBI
RGSC_v3.4252,496,517 - 52,658,066 (-)RGD
Celera248,257,266 - 48,408,640 (-)RGD
Sequence:
RefSeq Acc Id: XM_008760754   ⟹   XP_008758976
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2252,541,454 - 52,804,960 (-)NCBI
Rnor_6.0253,149,225 - 53,413,954 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039101769   ⟹   XP_038957697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2252,541,452 - 52,794,526 (-)NCBI
RefSeq Acc Id: XM_039101770   ⟹   XP_038957698
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2252,541,452 - 52,803,747 (-)NCBI
RefSeq Acc Id: XM_039101771   ⟹   XP_038957699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2252,551,636 - 52,804,960 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_058790   ⟸   NM_017094
- Peptide Label: precursor
- UniProtKB: P16310 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008758976   ⟸   XM_008760754
- Peptide Label: isoform X1
- UniProtKB: P16310 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021081   ⟸   ENSRNOT00000021081
RefSeq Acc Id: ENSRNOP00000072873   ⟸   ENSRNOT00000081558
RefSeq Acc Id: ENSRNOP00000044119   ⟸   ENSRNOT00000046951
RefSeq Acc Id: ENSRNOP00000071833   ⟸   ENSRNOT00000088876
RefSeq Acc Id: XP_038957698   ⟸   XM_039101770
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038957697   ⟸   XM_039101769
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038957699   ⟸   XM_039101771
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000096274   ⟸   ENSRNOT00000096351
Protein Domains
EpoR_lig-bind   Fibronectin type-III   GHBP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16310-F1-model_v2 AlphaFold P16310 1-638 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691161
Promoter ID:EPDNEW_R1686
Type:single initiation site
Name:Ghr_2
Description:growth hormone receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1687  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0253,313,805 - 53,313,865EPDNEW
RGD ID:13691168
Promoter ID:EPDNEW_R1687
Type:initiation region
Name:Ghr_1
Description:growth hormone receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1686  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0253,413,708 - 53,413,768EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2687 AgrOrtholog
BioCyc Gene G2FUF-54204 BioCyc
Ensembl Genes ENSRNOG00000015654 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021081 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000044119 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000071833 UniProtKB/TrEMBL
  ENSRNOP00000072873 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021081 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000046951 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000081558 UniProtKB/TrEMBL
  ENSRNOT00000088876 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth/epo_recpt_lig-bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Long_hematopoietin_rcpt_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25235 UniProtKB/Swiss-Prot
NCBI Gene 25235 ENTREZGENE
Pfam EpoR_lig-bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GHBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GHR RGD
PhenoGen Ghr PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMATOPO_REC_L_F1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K423_RAT UniProtKB/TrEMBL
  A0A0H2UHM8_RAT UniProtKB/TrEMBL
  A0A8A1UAK4_RAT UniProtKB/TrEMBL
  A0A8A1UAN7_RAT UniProtKB/TrEMBL
  A0A8A1UD65_RAT UniProtKB/TrEMBL
  A0A8A1UF68_RAT UniProtKB/TrEMBL
  GHR_RAT UniProtKB/Swiss-Prot
  H6AC53_RAT UniProtKB/TrEMBL
  I1SRC4_RAT UniProtKB/TrEMBL
  P16310 ENTREZGENE
  Q5RJL5_RAT UniProtKB/TrEMBL
  Q80WG8_RAT UniProtKB/TrEMBL
UniProt Secondary Q64236 UniProtKB/Swiss-Prot
  Q80XW9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ghr  growth hormone receptor      Symbol and Name status set to approved 70586 APPROVED