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Gene: Ghr (growth hormone receptor) Mus musculus
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Symbol: Ghr
Name: growth hormone receptor
Description: Exhibits growth hormone receptor activity and peptide hormone binding activity. Involved in several processes, including growth hormone receptor signaling pathway; positive regulation of peptidyl-tyrosine phosphorylation; and taurine metabolic process. Localizes to the extrinsic component of membrane; nucleus; and plasma membrane. Used to study Laron syndrome. Human ortholog(s) of this gene implicated in several diseases, including Laron syndrome; familial hypercholesterolemia; isolated growth hormone deficiency; osteoarthritis; and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human GHR (growth hormone receptor); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA986417; GH receptor; GHBP; GHR/BP; Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein); growth hormone receptor/binding protein; growth hormone receptor/binding protein, high molecular weight; growth hormone receptor/binding protein, low molecular weight; somatotropin receptor
Orthologs:
Homo sapiens (human) : GHR (growth hormone receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ghr (growth hormone receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ghr (growth hormone receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : GHR (growth hormone receptor)
Canis lupus familiaris (dog) : GHR (growth hormone receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ghr (growth hormone receptor)
Sus scrofa (pig) : GHR (growth hormone receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38153,317,755 - 3,583,352 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37153,267,760 - 3,533,230 (-)NCBIGRCm37mm9NCBIm37
MGSCv36153,267,774 - 3,533,231 (-)NCBImm8
Celera153,182,316 - 3,449,004 (-)NCBICelera
Cytogenetic Map15 A1NCBI
cM Map151.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ghr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10644
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.