(R)-mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein]] CTD PMID:16534557 1,2-dimethylhydrazine decreases expression ISO RGD:69103 6480464 1, 2-Dimethylhydrazine results in decreased expression of JAK1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol affects expression ISO RGD:69103 6480464 Ethinyl Estradiol affects the expression of JAK1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol decreases expression ISO RGD:69103 6480464 Ethinyl Estradiol results in decreased expression of JAK1 mRNA CTD PMID:16467188 , PMID:17942748 17beta-estradiol increases expression ISO RGD:69102 6480464 Estradiol results in increased expression of JAK1 mRNA CTD PMID:31614463 2,2',4,4',5,5'-hexachlorobiphenyl increases phosphorylation ISO RGD:69102 6480464 2 more ... CTD PMID:19632255 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:69102 6480464 Filipin inhibits the reaction [2 more ... CTD PMID:19632255 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:69103 6480464 Tetrachlorodibenzodioxin results in increased expression of JAK1 mRNA CTD PMID:18691609 , PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of JAK1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:69103 6480464 Tetrachlorodibenzodioxin affects the expression of JAK1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of JAK1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69102 6480464 Tetrachlorodibenzodioxin results in decreased expression of JAK1 mRNA CTD PMID:19574409 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:69102 6480464 Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to JAK1 gene] CTD PMID:19574409 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of JAK1 mRNA CTD PMID:21346803 3,4-methylenedioxymethamphetamine increases expression ISO RGD:69103 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of JAK1 mRNA CTD PMID:20188158 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of JAK1 mRNA CTD PMID:28522335 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of JAK1 protein] CTD PMID:32628957 4-hydroxyphenyl retinamide increases expression ISO RGD:69102 6480464 Fenretinide results in increased expression of JAK1 protein CTD PMID:15059897 4-vinylcyclohexene dioxide affects expression ISO RGD:69103 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of JAK1 mRNA CTD PMID:20829426 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of JAK1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of JAK1 mRNA CTD PMID:19483382 6alpha-methylprednisolone multiple interactions ISO RGD:69102 6480464 Methylprednisolone inhibits the reaction [IL4 protein results in increased phosphorylation of JAK1 protein] CTD PMID:11997017 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of JAK1 mRNA CTD PMID:28959563 aflatoxin B1 increases expression ISO RGD:69102 6480464 Aflatoxin B1 results in increased expression of JAK1 mRNA CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:69102 6480464 Tretinoin results in increased expression of JAK1 mRNA CTD PMID:21934132 all-trans-retinoic acid decreases expression ISO RGD:69102 6480464 Tretinoin results in decreased expression of JAK1 mRNA CTD PMID:15498508 amantadine increases expression ISO RGD:69102 6480464 Amantadine results in increased expression of JAK1 protein CTD PMID:16756086 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of JAK1 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of JAK1 mRNA CTD PMID:16483693 aristolochic acid A decreases expression ISO RGD:69102 6480464 aristolochic acid I results in decreased expression of JAK1 mRNA CTD PMID:33212167 aristolochic acids multiple interactions ISO RGD:69102 6480464 Aristolochic Acids inhibits the reaction [EPO protein results in increased phosphorylation of JAK1 protein] CTD PMID:26136230 arsane decreases expression ISO RGD:69103 6480464 Arsenic results in decreased expression of JAK1 mRNA CTD PMID:19654921 arsane increases phosphorylation ISO RGD:69102 6480464 Arsenic results in increased phosphorylation of JAK1 protein CTD PMID:35031324 arsenic atom decreases expression ISO RGD:69103 6480464 Arsenic results in decreased expression of JAK1 mRNA CTD PMID:19654921 arsenic atom increases phosphorylation ISO RGD:69102 6480464 Arsenic results in increased phosphorylation of JAK1 protein CTD PMID:35031324 arsenite(3-) multiple interactions ISO RGD:69102 6480464 arsenite inhibits the reaction [G3BP1 protein binds to JAK1 mRNA] CTD PMID:32406909 arsenous acid increases phosphorylation ISO RGD:69102 6480464 Arsenic Trioxide results in increased phosphorylation of JAK1 protein CTD PMID:19951532 arsenous acid decreases expression ISO RGD:69102 6480464 Arsenic Trioxide results in decreased expression of JAK1 mRNA CTD PMID:33634982 arsenous acid multiple interactions ISO RGD:69102 6480464 Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein] more ... CTD PMID:12492118 , PMID:33634982 baricitinib decreases activity ISO RGD:69102 6480464 baricitinib results in decreased activity of JAK1 protein CTD PMID:29687421 baricitinib multiple interactions ISO RGD:69102 6480464 baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK1 protein] CTD PMID:23968543 Benoxacor decreases expression ISO RGD:69103 6480464 benoxacor results in decreased expression of JAK1 mRNA CTD PMID:34850242 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of JAK1 mRNA CTD PMID:19483382 benzo[a]pyrene increases expression ISO RGD:69103 6480464 Benzo(a)pyrene results in increased expression of JAK1 mRNA CTD PMID:22228805 benzo[a]pyrene decreases methylation ISO RGD:69102 6480464 Benzo(a)pyrene results in decreased methylation of JAK1 promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:69102 6480464 Benzo(a)pyrene results in increased methylation of JAK1 5' UTR CTD PMID:27901495 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:69102 6480464 7 more ... CTD PMID:20018196 bisphenol A decreases expression ISO RGD:69102 6480464 bisphenol A results in decreased expression of JAK1 mRNA CTD PMID:22576693 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of JAK1 mRNA CTD PMID:30816183 more ... bisphenol A increases phosphorylation ISO RGD:69103 6480464 bisphenol A results in increased phosphorylation of JAK1 protein CTD PMID:30609183 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of JAK1 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO RGD:69102 6480464 bisphenol A results in increased methylation of JAK1 gene CTD PMID:22576693 bortezomib decreases expression ISO RGD:69102 6480464 Bortezomib results in decreased expression of JAK1 mRNA CTD PMID:20977926 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of JAK1 mRNA CTD PMID:24136188 cadmium dichloride decreases phosphorylation ISO RGD:69102 6480464 Cadmium Chloride results in decreased phosphorylation of JAK1 protein CTD PMID:19635391 calcitriol multiple interactions ISO RGD:69102 6480464 JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] CTD PMID:26091108 capsaicin multiple interactions ISO RGD:69102 6480464 Capsaicin results in decreased phosphorylation of and results in decreased activity of JAK1 protein CTD PMID:17505005 carbon nanotube decreases expression ISO RGD:69102 6480464 Nanotubes, Carbon results in decreased expression of JAK1 mRNA CTD PMID:15585362 Cirsimarin multiple interactions ISO RGD:69103 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK1 protein] CTD PMID:30053449 clobetasol decreases expression ISO RGD:69103 6480464 Clobetasol results in decreased expression of JAK1 mRNA CTD PMID:27462272 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of JAK1 mRNA CTD PMID:19483382 clofibrate decreases expression ISO RGD:69103 6480464 Clofibrate results in decreased expression of JAK1 mRNA CTD PMID:17585979 copper atom multiple interactions ISO RGD:69103 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of JAK1 mRNA CTD PMID:15467011 copper atom multiple interactions ISO RGD:69102 6480464 [Chelating Agents binds to Copper] which results in increased expression of JAK1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:69103 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of JAK1 mRNA CTD PMID:15467011 copper(0) multiple interactions ISO RGD:69102 6480464 [Chelating Agents binds to Copper] which results in increased expression of JAK1 mRNA CTD PMID:30911355 copper(II) sulfate increases expression ISO RGD:69102 6480464 Copper Sulfate results in increased expression of JAK1 mRNA CTD PMID:19549813 cyanidin cation multiple interactions ISO RGD:69103 6480464 cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein] CTD PMID:32044269 cyclosporin A increases expression ISO RGD:69102 6480464 Cyclosporine results in increased expression of JAK1 mRNA CTD PMID:25562108 DDT multiple interactions ISO RGD:69102 6480464 Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein], ruxolitinib inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein] CTD PMID:24820114 DDT increases phosphorylation ISO RGD:69102 6480464 DDT results in increased phosphorylation of JAK1 protein CTD PMID:24820114 deoxynivalenol increases expression ISO RGD:69103 6480464 deoxynivalenol results in increased expression of JAK1 mRNA CTD PMID:22454431 diarsenic trioxide increases phosphorylation ISO RGD:69102 6480464 Arsenic Trioxide results in increased phosphorylation of JAK1 protein CTD PMID:19951532 diarsenic trioxide decreases expression ISO RGD:69102 6480464 Arsenic Trioxide results in decreased expression of JAK1 mRNA CTD PMID:33634982 diarsenic trioxide multiple interactions ISO RGD:69102 6480464 Arsenic Trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein] more ... CTD PMID:12492118 , PMID:33634982 dioxygen increases expression ISO RGD:69103 6480464 Oxygen deficiency results in increased expression of JAK1 mRNA CTD PMID:24205000 divanadium pentaoxide multiple interactions ISO RGD:69102 6480464 JAK1 protein affects the reaction [vanadium pentoxide results in increased activity of STAT1 protein] CTD PMID:18322232 dorsomorphin multiple interactions ISO RGD:69102 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:69102 6480464 Doxorubicin results in decreased expression of JAK1 mRNA CTD PMID:29803840 emodin decreases phosphorylation ISO RGD:69102 6480464 Emodin results in decreased phosphorylation of JAK1 protein CTD PMID:23848338 emodin multiple interactions ISO RGD:69102 6480464 Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein] CTD PMID:23848338 ethanol multiple interactions EXP 6480464 Ethanol promotes the reaction [IL10 protein results in increased phosphorylation of JAK1 protein] CTD PMID:20052772 ethanol affects splicing ISO RGD:69103 6480464 Ethanol affects the splicing of JAK1 mRNA CTD PMID:30319688 Fidarestat decreases phosphorylation ISO RGD:69102 6480464 fidarestat results in decreased phosphorylation of JAK1 protein CTD PMID:21203431 Fidarestat multiple interactions ISO RGD:69102 6480464 fidarestat inhibits the reaction [IL13 protein results in increased phosphorylation of JAK1 protein] CTD PMID:21203431 filipin III multiple interactions ISO RGD:69102 6480464 Filipin inhibits the reaction [2 more ... CTD PMID:19632255 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of JAK1 mRNA CTD PMID:22061828 hesperetin multiple interactions ISO RGD:69103 6480464 hesperetin analog affects the reaction [PPARG protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of JAK1 protein]], hesperetin analog inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK1 protein] CTD PMID:28428136 hexadecanoic acid multiple interactions ISO RGD:69102 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein more ... CTD PMID:30547786 hydrogen peroxide multiple interactions ISO RGD:69102 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of JAK1 protein CTD PMID:18951874 hydrogen peroxide decreases expression ISO RGD:69102 6480464 Hydrogen Peroxide results in decreased expression of JAK1 mRNA CTD PMID:18951874 isotretinoin increases expression ISO RGD:69102 6480464 Isotretinoin results in increased expression of JAK1 mRNA CTD PMID:20436886 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of JAK1 mRNA CTD PMID:19483382 lead diacetate multiple interactions ISO RGD:69103 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of JAK1 protein CTD PMID:32428222 lead(0) multiple interactions ISO RGD:69103 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of JAK1 protein CTD PMID:32428222 lead(2+) multiple interactions ISO RGD:69103 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of JAK1 protein CTD PMID:32428222 lipopolysaccharide multiple interactions ISO RGD:69102 6480464 JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] CTD PMID:26091108 lipopolysaccharide increases phosphorylation ISO RGD:69103 6480464 Lipopolysaccharides results in increased phosphorylation of JAK1 protein CTD PMID:25576658 more ... lipopolysaccharide increases expression ISO RGD:69103 6480464 Lipopolysaccharides results in increased expression of JAK1 mRNA CTD PMID:15919760 lipopolysaccharide multiple interactions ISO RGD:69103 6480464 cirsimarin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JAK1 protein] more ... CTD PMID:25576658 more ... lycopene increases expression ISO RGD:69102 6480464 lycopene results in increased expression of JAK1 mRNA CTD PMID:16886892 menadione affects expression ISO RGD:69103 6480464 Vitamin K 3 affects the expression of JAK1 mRNA CTD PMID:20829426 mercury dichloride decreases phosphorylation ISO RGD:69102 6480464 Mercuric Chloride results in decreased phosphorylation of JAK1 protein CTD PMID:16896058 , PMID:19635391 methoxychlor affects expression ISO RGD:69103 6480464 Methoxychlor affects the expression of JAK1 mRNA CTD PMID:20829426 methyl beta-cyclodextrin multiple interactions ISO RGD:69102 6480464 methyl-beta-cyclodextrin inhibits the reaction [2 more ... CTD PMID:19632255 methylmercury chloride increases expression ISO RGD:69102 6480464 methylmercuric chloride results in increased expression of JAK1 mRNA CTD PMID:28001369 methylseleninic acid affects expression ISO RGD:69102 6480464 methylselenic acid affects the expression of JAK1 mRNA CTD PMID:14617803 methylseleninic acid increases expression ISO RGD:69102 6480464 methylselenic acid results in increased expression of JAK1 mRNA CTD PMID:18548127 microcystin-LR increases expression ISO RGD:69103 6480464 cyanoginosin LR results in increased expression of JAK1 mRNA CTD PMID:17654400 myricetin multiple interactions ISO RGD:69103 6480464 myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein] CTD PMID:18995957 myricetin affects binding ISO RGD:69102 6480464 myricetin binds to JAK1 protein CTD PMID:18995957 N-acetyl-L-cysteine multiple interactions ISO RGD:69102 6480464 Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein] CTD PMID:24820114 N-ethyl-N-nitrosourea increases phosphorylation ISO RGD:69103 6480464 Ethylnitrosourea results in increased phosphorylation of JAK1 protein CTD PMID:27725143 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of JAK1 protein CTD PMID:29698782 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of JAK1 mRNA CTD PMID:24136188 nitric oxide decreases expression ISO RGD:69103 6480464 Nitric Oxide deficiency results in decreased expression of JAK1 mRNA CTD PMID:15878706 oleic acid multiple interactions ISO RGD:69102 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein more ... CTD PMID:30547786 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of JAK1 mRNA CTD PMID:19483382 oridonin multiple interactions ISO RGD:69102 6480464 oridonin analog inhibits the reaction [IL6 protein promotes the reaction [JAK1 protein modified form binds to STAT3 protein]], oridonin analog inhibits the reaction [JAK1 protein results in increased phosphorylation of STAT3 protein] CTD PMID:31594861 paracetamol affects expression ISO RGD:69103 6480464 Acetaminophen affects the expression of JAK1 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:69102 6480464 Acetaminophen results in increased expression of JAK1 mRNA CTD PMID:22230336 perfluorooctanoic acid decreases expression ISO RGD:69102 6480464 perfluorooctanoic acid results in decreased expression of JAK1 protein CTD PMID:26879310 phenethyl isothiocyanate decreases expression EXP 6480464 phenethyl isothiocyanate results in decreased expression of JAK1 mRNA CTD PMID:17616710 phenobarbital decreases expression ISO RGD:69103 6480464 Phenobarbital results in decreased expression of JAK1 mRNA CTD PMID:23091169 phenylmercury acetate increases expression ISO RGD:69102 6480464 Phenylmercuric Acetate results in increased expression of JAK1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:69102 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of JAK1 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:69102 6480464 JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] CTD PMID:26091108 pipoxolan multiple interactions ISO RGD:69103 6480464 pipoxolan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK1 protein] CTD PMID:32677756 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of JAK1 mRNA CTD PMID:19483382 ponatinib decreases activity ISO RGD:69102 6480464 ponatinib results in decreased activity of JAK1 protein CTD PMID:19878872 potassium dichromate increases expression ISO RGD:69102 6480464 Potassium Dichromate results in increased expression of JAK1 protein CTD PMID:23718831 propiconazole increases expression ISO RGD:69103 6480464 propiconazole results in increased expression of JAK1 mRNA CTD PMID:21278054 Punicalagin decreases expression ISO RGD:69102 6480464 punicalagin results in decreased expression of JAK1 protein CTD PMID:33720461 quercetin multiple interactions ISO RGD:69102 6480464 Quercetin inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein] CTD PMID:22394507 quercetin decreases phosphorylation ISO RGD:69102 6480464 Quercetin results in decreased phosphorylation of JAK1 protein CTD PMID:27175602 quercetin multiple interactions ISO RGD:69103 6480464 Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of JAK1 protein] CTD PMID:20060843 quercetin decreases expression ISO RGD:69102 6480464 Quercetin results in decreased expression of JAK1 mRNA CTD PMID:21632981 quercetin 3-O-beta-D-glucofuranoside increases expression ISO RGD:69102 6480464 isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 quercetin 3-O-beta-D-glucopyranoside increases expression ISO RGD:69102 6480464 isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 resveratrol decreases expression ISO RGD:69102 6480464 resveratrol results in decreased expression of JAK1 mRNA, resveratrol results in decreased expression of JAK1 protein CTD PMID:22254182 , PMID:25667456 resveratrol multiple interactions ISO RGD:69103 6480464 IL10 protein affects the reaction [resveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of JAK1 protein]], resveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of JAK1 protein] CTD PMID:25576658 resveratrol decreases phosphorylation ISO RGD:69102 6480464 resveratrol results in decreased phosphorylation of JAK1 protein CTD PMID:26911335 rotenone multiple interactions ISO RGD:69102 6480464 Rotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of JAK1 protein] CTD PMID:15748169 rotenone decreases phosphorylation ISO RGD:69102 6480464 Rotenone results in decreased phosphorylation of JAK1 protein CTD PMID:19635391 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of JAK1 mRNA] CTD PMID:26062544 ruxolitinib multiple interactions ISO RGD:69102 6480464 ruxolitinib inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein] CTD PMID:24820114 ruxolitinib decreases activity ISO RGD:69102 6480464 ruxolitinib results in decreased activity of JAK1 protein CTD PMID:24883332 , PMID:26300391 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO RGD:69103 6480464 Buthionine Sulfoximine results in increased expression of JAK1 mRNA CTD PMID:15878706 Salinomycin multiple interactions ISO RGD:69102 6480464 salinomycin inhibits the reaction [IFNG protein results in increased phosphorylation of JAK1 protein] CTD PMID:32822738 SB 431542 multiple interactions ISO RGD:69102 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein]], Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein] CTD PMID:16534557 sodium arsenite multiple interactions ISO RGD:69102 6480464 sodium arsenite inhibits the reaction [IFNG protein results in increased activity of JAK1 protein] more ... CTD PMID:15116095 sodium arsenite increases expression ISO RGD:69103 6480464 sodium arsenite results in increased expression of JAK1 mRNA CTD PMID:36209798 sodium arsenite decreases expression ISO RGD:69102 6480464 sodium arsenite results in decreased expression of JAK1 mRNA CTD PMID:12679051 , PMID:34032870 sunitinib increases expression ISO RGD:69102 6480464 Sunitinib results in increased expression of JAK1 mRNA CTD PMID:31533062 T-2 toxin increases expression ISO RGD:69103 6480464 T-2 Toxin results in increased expression of JAK1 mRNA CTD PMID:22454431 tamibarotene affects expression ISO RGD:69102 6480464 tamibarotene affects the expression of JAK1 mRNA CTD PMID:15498508 tamoxifen affects expression ISO RGD:69103 6480464 Tamoxifen affects the expression of JAK1 mRNA CTD PMID:17555576 temozolomide decreases expression ISO RGD:69102 6480464 Temozolomide results in decreased expression of JAK1 mRNA CTD PMID:31758290 testosterone increases expression EXP 6480464 Testosterone results in increased expression of JAK1 protein CTD PMID:32628957 testosterone multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased expression of JAK1 protein] CTD PMID:32628957 testosterone enanthate increases expression EXP 6480464 testosterone enanthate results in increased expression of JAK1 mRNA CTD PMID:25603467 tetrachloromethane multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of JAK1 mRNA] CTD PMID:26062544 tetrachloromethane increases phosphorylation ISO RGD:69103 6480464 Carbon Tetrachloride results in increased phosphorylation of JAK1 protein CTD PMID:28428136 tetrachloromethane multiple interactions ISO RGD:69103 6480464 hesperetin analog inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK1 protein], Silymarin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK1 protein] CTD PMID:28428136 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of JAK1 mRNA CTD PMID:26062544 tetracycline increases expression ISO RGD:69103 6480464 Tetracycline results in increased expression of JAK1 mRNA CTD PMID:16917069 thapsigargin increases expression ISO RGD:69103 6480464 Thapsigargin results in increased expression of JAK1 protein CTD PMID:24648495 theophylline multiple interactions ISO RGD:69102 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of JAK1 protein CTD PMID:18951874 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of JAK1 mRNA CTD PMID:19483382 tofacitinib decreases activity ISO RGD:69102 6480464 tofacitinib results in decreased activity of JAK1 protein CTD PMID:24883332 tofacitinib multiple interactions ISO RGD:69102 6480464 tofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK1 protein], tofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of JAK1 protein] CTD PMID:21548952 , PMID:23968543 torcetrapib increases expression ISO RGD:69102 6480464 torcetrapib results in increased expression of JAK1 mRNA CTD PMID:23228038 trichostatin A increases expression ISO RGD:69102 6480464 trichostatin A results in increased expression of JAK1 mRNA CTD PMID:24935251 trichostatin A affects expression ISO RGD:69102 6480464 trichostatin A affects the expression of JAK1 mRNA CTD PMID:28542535 trimethyltin increases expression ISO RGD:69103 6480464 trimethyltin results in increased expression of JAK1 mRNA CTD PMID:20833246 tungsten decreases expression ISO RGD:69103 6480464 Tungsten results in decreased expression of JAK1 mRNA CTD PMID:30912803 urethane increases expression ISO RGD:69102 6480464 Urethane results in increased expression of JAK1 mRNA CTD PMID:28818685 valproic acid increases expression ISO RGD:69103 6480464 Valproic Acid results in increased expression of JAK1 mRNA CTD PMID:20546886 valproic acid decreases methylation ISO RGD:69102 6480464 Valproic Acid results in decreased methylation of JAK1 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:69102 6480464 Valproic Acid affects the expression of JAK1 mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:69102 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of JAK1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:69102 6480464 Valproic Acid results in increased expression of JAK1 mRNA CTD PMID:23179753 more ... verteporfin multiple interactions ISO RGD:69103 6480464 [Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of JAK1 protein CTD PMID:31812773 verteporfin decreases expression ISO RGD:69103 6480464 Verteporfin results in decreased expression of JAK1 protein CTD PMID:31812773 zoledronic acid increases expression ISO RGD:69102 6480464 zoledronic acid results in increased expression of JAK1 mRNA CTD PMID:24714768