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Gene: Jak1 (Janus kinase 1) Rattus norvegicus
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Symbol: Jak1
Name: Janus kinase 1
Description: Exhibits CCR5 chemokine receptor binding activity and growth hormone receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; cellular response to cytokine stimulus; and positive regulation of receptor signaling pathway via STAT. Predicted to localize to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human JAK1 (Janus kinase 1); PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-2 signaling pathway; interleukin-27 signaling pathway; INTERACTS WITH (R)-mevalonic acid; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Janus protein tyrosine kinase 1; tyrosine-protein kinase JAK1
Orthologs:
Homo sapiens (human) : JAK1 (Janus kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Jak1 (Janus kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jak1 (Janus kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : JAK1 (Janus kinase 1)
Canis lupus familiaris (dog) : JAK1 (Janus kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jak1 (Janus kinase 1)
Sus scrofa (pig) : JAK1 (Janus kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05119,982,503 - 120,091,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5119,982,943 - 120,083,904 (-)Ensembl
Rnor_5.05123,865,078 - 123,973,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45121,804,586 - 121,905,581 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15121,813,666 - 121,843,676 (-)NCBI
Celera5114,318,185 - 114,418,922 (-)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Jak1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69056
Created: 2001-11-08
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.