Gene: Jak1 (Janus kinase 1) Rattus norvegicus
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Symbol: Jak1
Name: Janus kinase 1
Description: ENCODES a protein that exhibits CCR5 chemokine receptor binding; growth hormone receptor binding; protein phosphatase binding (ortholog); INVOLVED IN cellular response to interleukin-3 (ortholog); cellular response to interleukin-7 (ortholog); cytokine-mediated signaling pathway (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; interleukin-2 signaling pathway; interleukin-27 signaling pathway; ASSOCIATED WITH Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); acute myeloid leukemia (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (R)-mevalonic acid; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Janus protein tyrosine kinase 1; tyrosine-protein kinase JAK1
Orthologs:
Homo sapiens (human) : JAK1 (Janus kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Jak1 (Janus kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jak1 (Janus kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : JAK1 (Janus kinase 1)
Canis lupus familiaris (dog) : JAK1 (Janus kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jak1 (Janus kinase 1)
Sus scrofa (pig) : JAK1 (Janus kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05119,982,503 - 120,091,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05123,865,078 - 123,973,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45121,804,586 - 121,905,581 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15121,813,666 - 121,843,676 (-)NCBI
Celera5114,318,185 - 114,418,922 (-)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Jak1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69056
Created: 2001-11-08
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE