Ghr (growth hormone receptor) - Rat Genome Database

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Gene: Ghr (growth hormone receptor) Heterocephalus glaber
Analyze
Symbol: Ghr
Name: growth hormone receptor
RGD ID: 18912947
Description: ENCODES a protein that exhibits growth factor binding (ortholog); growth hormone receptor activity (ortholog); identical protein binding (ortholog); INVOLVED IN activation of Janus kinase activity (ortholog); cartilage development involved in endochondral bone morphogenesis (ortholog); cell surface receptor signaling pathway via JAK-STAT (ortholog); PARTICIPATES IN growth hormone signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Brain Hypoxia-Ischemia (ortholog); breast cancer (ortholog); FOUND IN cell surface (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475912,285,594 - 12,570,906 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475912,282,295 - 12,570,106 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ghr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475912,285,594 - 12,570,906 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475912,282,295 - 12,570,106 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GHR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38542,423,439 - 42,721,878 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl542,423,439 - 42,721,878 (+)EnsemblGRCh38hg38GRCh38
GRCh37542,423,541 - 42,721,980 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36542,459,783 - 42,757,683 (+)NCBINCBI36Build 36hg18NCBI36
Build 34542,459,782 - 42,757,682NCBI
Celera542,314,115 - 42,611,474 (+)NCBICelera
Cytogenetic Map5p13.1-p12NCBI
HuRef542,375,464 - 42,673,429 (+)NCBIHuRef
CHM1_1542,425,901 - 42,723,964 (+)NCBICHM1_1
T2T-CHM13v2.0542,678,916 - 42,974,806 (+)NCBIT2T-CHM13v2.0
Ghr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,347,237 - 3,612,834 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl153,347,242 - 3,612,974 (-)EnsemblGRCm39 Ensembl
GRCm38153,317,755 - 3,583,352 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,317,760 - 3,583,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv37153,267,760 - 3,533,230 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36153,267,774 - 3,533,231 (-)NCBIMGSCv36mm8
Celera153,182,321 - 3,448,882 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.84NCBI
Ghr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8254,269,066 - 54,532,595 (-)NCBIGRCr8
mRatBN7.2252,541,452 - 52,804,960 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl252,542,594 - 52,804,735 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx259,642,577 - 59,799,676 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0257,701,311 - 57,858,396 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0252,732,297 - 52,881,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0253,149,225 - 53,413,954 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,150,370 - 53,413,638 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0272,265,571 - 72,346,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0272,182,692 - 72,218,250 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4252,496,517 - 52,658,066 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1252,424,749 - 52,586,299 (-)NCBI
Celera248,257,266 - 48,408,640 (-)NCBICelera
RH 3.4 Map2332.2RGD
Cytogenetic Map2q16NCBI
Ghr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542626,689,581 - 26,871,684 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542626,553,509 - 26,873,619 (+)NCBIChiLan1.0ChiLan1.0
GHR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2467,606,168 - 67,904,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1565,759,794 - 66,082,475 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0567,654,326 - 67,953,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1572,700,150 - 72,997,356 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl572,700,150 - 72,871,278 (-)Ensemblpanpan1.1panPan2
GHR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1467,021,821 - 67,245,499 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl467,022,252 - 67,290,473 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha466,705,544 - 66,845,096 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0467,531,090 - 67,802,322 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl467,532,966 - 67,802,335 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1467,276,975 - 67,416,597 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0467,407,363 - 67,546,744 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0467,943,814 - 68,083,513 (-)NCBIUU_Cfam_GSD_1.0
Ghr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213230,991,608 - 231,135,845 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936518235,990 - 380,272 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936518235,996 - 380,225 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1627,126,734 - 27,421,449 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11627,126,300 - 27,422,618 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21628,691,739 - 28,855,136 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1441,171,038 - 41,464,474 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl441,285,712 - 41,464,666 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607131,608,844 - 31,907,481 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004848566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004848567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004848568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021261452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF332034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01039613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH166329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000004781   ⟹   ENSHGLP00000004718
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475912,285,594 - 12,570,906 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000004782   ⟹   ENSHGLP00000004719
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475912,285,594 - 12,319,847 (-)Ensembl
RefSeq Acc Id: XM_004848566   ⟹   XP_004848623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,464,020 (-)NCBI
RefSeq Acc Id: XM_004848567   ⟹   XP_004848624
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,570,106 (-)NCBI
RefSeq Acc Id: XM_004848568   ⟹   XP_004848625
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,569,586 (-)NCBI
RefSeq Acc Id: XM_021261444   ⟹   XP_021117103
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,283,570 - 12,464,022 (-)NCBI
RefSeq Acc Id: XM_021261445   ⟹   XP_021117104
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,464,022 (-)NCBI
RefSeq Acc Id: XM_021261446   ⟹   XP_021117105
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,464,021 (-)NCBI
RefSeq Acc Id: XM_021261447   ⟹   XP_021117106
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,464,021 (-)NCBI
RefSeq Acc Id: XM_021261448   ⟹   XP_021117107
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,570,106 (-)NCBI
RefSeq Acc Id: XM_021261449   ⟹   XP_021117108
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,569,586 (-)NCBI
RefSeq Acc Id: XM_021261450   ⟹   XP_021117109
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,285,594 - 12,335,453 (-)NCBI
RefSeq Acc Id: XM_021261451   ⟹   XP_021117110
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,282,295 - 12,464,024 (-)NCBI
RefSeq Acc Id: XM_021261452   ⟹   XP_021117111
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475912,283,570 - 12,464,024 (-)NCBI
RefSeq Acc Id: XP_021117110   ⟸   XM_021261451
- Peptide Label: isoform X7
- UniProtKB: A0AAX6T876 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117111   ⟸   XM_021261452
- Peptide Label: isoform X8
- UniProtKB: A0AAX6T9K4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117103   ⟸   XM_021261444
- Peptide Label: isoform X1
- UniProtKB: A0AAX6TAH8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117107   ⟸   XM_021261448
- Peptide Label: isoform X5
- UniProtKB: A0AAX6T4S5 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848624   ⟸   XM_004848567
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PBY2 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117108   ⟸   XM_021261449
- Peptide Label: isoform X5
- UniProtKB: A0AAX6T4S5 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848625   ⟸   XM_004848568
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PBY2 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117104   ⟸   XM_021261445
- Peptide Label: isoform X2
- UniProtKB: A0AAX6T992 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117106   ⟸   XM_021261447
- Peptide Label: isoform X5
- UniProtKB: A0AAX6T4S5 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117105   ⟸   XM_021261446
- Peptide Label: isoform X3
- UniProtKB: A0AAX6T695 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848623   ⟸   XM_004848566
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PBY2 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117109   ⟸   XM_021261450
- Peptide Label: isoform X6
- UniProtKB: A0AAX6T8L8 (UniProtKB/TrEMBL),   G5APA5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004718   ⟸   ENSHGLT00000004781
Ensembl Acc Id: ENSHGLP00000004719   ⟸   ENSHGLT00000004782


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003459 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004781 ENTREZGENE
  ENSHGLT00000004782 ENTREZGENE
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  GHBP UniProtKB/TrEMBL
  Growth/epo_recpt_lig-bind UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Long_hematopoietin_rcpt_CS UniProtKB/TrEMBL
NCBI Gene Ghr ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  INTERLEUKIN 5 RECEPTOR SUBUNIT ALPHA UniProtKB/TrEMBL
Pfam EpoR_lig-bind UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  GHBP UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  HEMATOPO_REC_L_F1 UniProtKB/TrEMBL
Superfamily-SCOP Fibronectin type III UniProtKB/TrEMBL
UniProt A0AAX6PBY2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T4S5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T695 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T876 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T8L8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T992 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T9K4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TAH8 ENTREZGENE, UniProtKB/TrEMBL
  G5APA5 ENTREZGENE, UniProtKB/TrEMBL
  Q924F3_HETGA UniProtKB/TrEMBL