Tsc22d3 (TSC22 domain family, member 3) - Rat Genome Database

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Pathways
Gene: Tsc22d3 (TSC22 domain family, member 3) Rattus norvegicus
Analyze
Symbol: Tsc22d3
Name: TSC22 domain family, member 3
RGD ID: 621654
Description: Predicted to enable MRF binding activity. Involved in body fluid secretion. Predicted to be located in cytoplasm and nucleus. Orthologous to human TSC22D3 (TSC22 domain family member 3); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: delta sleep inducing peptide, immunoreactor; Dsipi; Gilz; glucocorticoid-induced leucine zipper; TSC22 domain family 3; TSC22 domain family protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X104,217,898 - 104,277,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX104,217,925 - 104,276,861 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX106,347,240 - 106,407,215 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X109,845,976 - 109,905,951 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X107,401,045 - 107,460,983 (-)NCBIRnor_WKY
Rnor_6.0X111,884,285 - 111,944,693 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX111,884,295 - 111,887,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0352,655,031 - 52,715,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X128,336,408 - 128,340,027 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X128,409,842 - 128,413,460 (-)NCBI
Celera343,710,349 - 43,713,973 (+)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dioxane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenoxybenzoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antimonite  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
azoxystrobin  (EXP)
barium chloride  (ISO)
barium(0)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
boron nitride  (ISO)
buspirone  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP,ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
corticosterone  (EXP)
cortisol  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
DDE  (ISO)
DDT  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dieldrin  (ISO)
dimethyl sulfoxide  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (EXP)
doxorubicin  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
Erionite  (ISO)
erythromycin estolate  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
fluoranthene  (EXP,ISO)
flutamide  (EXP)
folpet  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
genistein  (ISO)
geraniol  (ISO)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
lactacystin  (ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
levofloxacin  (EXP)
liquiritigenin  (ISO)
lithium atom  (ISO)
lithium chloride  (ISO)
lithium hydride  (ISO)
medroxyprogesterone acetate  (ISO)
mercury dichloride  (EXP)
methamphetamine  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
metyrapone  (EXP)
mifepristone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nevirapine  (EXP)
nickel sulfate  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
oxycodone  (EXP)
ozone  (EXP,ISO)
paclitaxel  (EXP)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (EXP,ISO)
Ptaquiloside  (ISO)
quercetin  (EXP)
resmethrin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thiabendazole  (EXP)
thifluzamide  (ISO)
tin atom  (ISO)
tin(0)  (ISO)
tin(II) chloride (anhydrous)  (ISO)
titanium dioxide  (ISO)
tolylfluanid  (ISO)
topotecan  (EXP)
trametinib  (ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
triclosan  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vandetanib  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Mineralocorticoid effects in the kidney: correlation between alphaENaC, GILZ, and Sgk-1 mRNA expression and urinary excretion of Na+ and K+. Muller OG, etal., J Am Soc Nephrol 2003 May;14(5):1107-15.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Delta sleep-inducing peptide blocks excitatory effects of glutamate on rat brain neurons. Umriukhin PE Bull Exp Biol Med 2002 Jul;134(1):5-7.
Additional References at PubMed
PMID:9430225   PMID:15489334   PMID:17147695   PMID:17956870   PMID:18643788   PMID:20124407   PMID:22094385   PMID:22124125   PMID:23090754   PMID:25299205   PMID:28728173   PMID:31485805  


Genomics

Comparative Map Data
Tsc22d3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X104,217,898 - 104,277,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX104,217,925 - 104,276,861 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX106,347,240 - 106,407,215 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X109,845,976 - 109,905,951 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X107,401,045 - 107,460,983 (-)NCBIRnor_WKY
Rnor_6.0X111,884,285 - 111,944,693 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX111,884,295 - 111,887,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0352,655,031 - 52,715,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X128,336,408 - 128,340,027 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X128,409,842 - 128,413,460 (-)NCBI
Celera343,710,349 - 43,713,973 (+)NCBICelera
Cytogenetic MapXq32NCBI
TSC22D3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X107,713,221 - 107,775,988 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX107,713,221 - 107,777,342 (-)EnsemblGRCh38hg38GRCh38
GRCh37X106,956,451 - 107,019,218 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,843,107 - 106,905,673 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX107,427,403 - 107,489,966 (-)NCBICelera
Cytogenetic MapXq22.3NCBI
HuRefX96,580,831 - 96,643,067 (-)NCBIHuRef
CHM1_1X106,867,386 - 106,929,923 (-)NCBICHM1_1
T2T-CHM13v2.0X106,149,979 - 106,212,727 (-)NCBIT2T-CHM13v2.0
Tsc22d3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X139,440,277 - 139,501,257 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX139,440,277 - 139,501,408 (-)EnsemblGRCm39 Ensembl
GRCm38X140,539,528 - 140,600,522 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX140,539,528 - 140,600,659 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X137,074,067 - 137,135,061 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X135,885,892 - 135,889,531 (-)NCBIMGSCv36mm8
CeleraX123,798,019 - 123,859,465 (-)NCBICelera
Cytogenetic MapXF1NCBI
Tsc22d3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554908,177,356 - 8,238,373 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554908,177,356 - 8,238,373 (+)NCBIChiLan1.0ChiLan1.0
TSC22D3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1X107,193,129 - 107,257,315 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X96,806,179 - 96,870,020 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X107,179,077 - 107,242,902 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX107,179,077 - 107,242,902 (-)Ensemblpanpan1.1panPan2
TSC22D3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X81,235,489 - 81,298,290 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX81,235,809 - 81,298,192 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX67,355,142 - 67,417,939 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X82,882,231 - 82,945,043 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX82,882,234 - 82,944,500 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X80,342,439 - 80,405,260 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X82,054,298 - 82,117,113 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X81,846,235 - 81,908,809 (-)NCBIUU_Cfam_GSD_1.0
Tsc22d3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X80,613,791 - 80,680,477 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364996,977,686 - 7,045,294 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364996,977,924 - 7,044,173 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSC22D3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX88,230,048 - 88,233,098 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X88,171,325 - 88,233,583 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X102,611,634 - 102,673,219 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TSC22D3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X95,535,798 - 95,606,309 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606520,659,327 - 20,723,753 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tsc22d3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248038,701,221 - 8,763,529 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248038,701,348 - 8,762,194 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tsc22d3
117 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:233
Count of miRNA genes:151
Interacting mature miRNAs:200
Transcripts:ENSRNOT00000048080
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 47 31 19 31 8 11 74 35 38 11 8
Low 10 10 10 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000085118   ⟹   ENSRNOP00000072713
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX104,217,925 - 104,221,442 (-)Ensembl
Rnor_6.0 EnsemblX111,884,295 - 111,887,906 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108889   ⟹   ENSRNOP00000081403
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX104,217,925 - 104,227,193 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117710   ⟹   ENSRNOP00000080328
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX104,217,925 - 104,276,861 (-)Ensembl
RefSeq Acc Id: NM_031345   ⟹   NP_112635
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X104,217,898 - 104,221,523 (-)NCBI
Rnor_6.0X111,884,285 - 111,887,906 (-)NCBI
Rnor_5.0352,655,031 - 52,715,433 (+)NCBI
RGSC_v3.4X128,336,408 - 128,340,027 (-)RGD
Celera343,710,349 - 43,713,973 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006234249   ⟹   XP_006234311
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X104,217,898 - 104,276,691 (-)NCBI
Rnor_6.0X111,884,285 - 111,943,310 (-)NCBI
Rnor_5.0352,655,031 - 52,715,433 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006234250   ⟹   XP_006234312
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X104,217,898 - 104,277,935 (-)NCBI
Rnor_6.0X111,884,285 - 111,944,693 (-)NCBI
Rnor_5.0352,655,031 - 52,715,433 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006234251   ⟹   XP_006234313
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X104,217,898 - 104,277,013 (-)NCBI
Rnor_6.0X111,884,285 - 111,943,771 (-)NCBI
Rnor_5.0352,655,031 - 52,715,433 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773447   ⟹   XP_008771669
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X104,217,898 - 104,277,174 (-)NCBI
Rnor_6.0X111,884,285 - 111,943,934 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_112635   ⟸   NM_031345
- UniProtKB: Q9EQZ1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006234312   ⟸   XM_006234250
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006234313   ⟸   XM_006234251
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006234311   ⟸   XM_006234249
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZQF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771669   ⟸   XM_008773447
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZQF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072713   ⟸   ENSRNOT00000085118
RefSeq Acc Id: ENSRNOP00000080328   ⟸   ENSRNOT00000117710
RefSeq Acc Id: ENSRNOP00000081403   ⟸   ENSRNOT00000108889

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EQZ1-F1-model_v2 AlphaFold Q9EQZ1 1-134 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701957
Promoter ID:EPDNEW_R12481
Type:single initiation site
Name:Tsc22d3_1
Description:TSC22 domain family, member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X111,887,920 - 111,887,980EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621654 AgrOrtholog
BioCyc Gene G2FUF-1542 BioCyc
Ensembl Genes ENSRNOG00000056135 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000072713 ENTREZGENE
  ENSRNOP00000072713.1 UniProtKB/Swiss-Prot
  ENSRNOP00000080328 ENTREZGENE
  ENSRNOP00000080328.1 UniProtKB/TrEMBL
  ENSRNOP00000081403.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000085118 ENTREZGENE
  ENSRNOT00000085118.2 UniProtKB/Swiss-Prot
  ENSRNOT00000108889.1 UniProtKB/TrEMBL
  ENSRNOT00000117710 ENTREZGENE
  ENSRNOT00000117710.1 UniProtKB/TrEMBL
Gene3D-CATH Single helix bin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598145 IMAGE-MGC_LOAD
InterPro TSC-22_Dip_Bun UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83514 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72405 IMAGE-MGC_LOAD
NCBI Gene 83514 ENTREZGENE
PANTHER TSC22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSC22 DOMAIN FAMILY PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TSC22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tsc22d3 PhenoGen
PROSITE TSC22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Delta-sleep-inducing peptide immunoreactive peptide UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZSV8_RAT UniProtKB/TrEMBL
  Q9EQZ1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Tsc22d3  TSC22 domain family, member 3  Tsc22d3  TSC22 domain family 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tsc22d3  TSC22 domain family 3  Dsipi  delta sleep inducing peptide, immunoreactor  Symbol and Name updated 1299863 APPROVED
2004-12-14 Dsipi  delta sleep inducing peptide, immunoreactor  Gilz  glucocorticoid-induced leucine zipper  Symbol and Name updated 1299863 APPROVED
2002-08-07 Gilz  glucocorticoid-induced leucine zipper      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation mRNA induced by aldosterone 632721