Zwint (ZW10 interacting kinetochore protein) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Zwint (ZW10 interacting kinetochore protein) Rattus norvegicus
Analyze
Symbol: Zwint
Name: ZW10 interacting kinetochore protein
RGD ID: 628671
Description: Predicted to be involved in nuclear chromosome segregation and regulation of metaphase/anaphase transition of cell cycle. Located in dendrite. Orthologous to human ZWINT (ZW10 interacting kinetochore protein); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: neuroprotective protein 8; scoilin; Sip30; SNAP25 interacting protein 30; SNAP25-interacting protein 30; ZW10 interacting protein-1; ZW10 interactor; ZW10 interactor, kinetochore protein; ZW10-interacting protein 1; Zwint-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82015,502,559 - 15,953,701 (-)NCBIGRCr8
mRatBN7.22015,938,157 - 15,953,997 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2015,938,157 - 15,953,957 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2016,649,159 - 16,664,966 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02016,004,145 - 16,019,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02016,476,752 - 16,492,559 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02017,075,781 - 17,091,715 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2017,075,771 - 17,091,766 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02019,258,272 - 19,274,238 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2017,366,344 - 17,382,150 (-)NCBICelera
Cytogenetic Map20p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
antimony(0)  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol F  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
chromium atom  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
finasteride  (EXP)
fipronil  (EXP)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glucose  (EXP)
hypochlorous acid  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
inulin  (ISO)
L-ethionine  (EXP)
leflunomide  (EXP)
lucanthone  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury dichloride  (EXP)
mercury(0)  (ISO)
methidathion  (ISO)
miconazole  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
nimesulide  (EXP)
omeprazole  (EXP)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
quinolin-8-ol  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sotorasib  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trametinib  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vincaleukoblastine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,ISO)
dendrite  (IBA,IDA)
kinetochore  (IBA,IEA,ISO,ISS)
Knl1/Spc105 complex  (ISO,ISS)
nuclear body  (IBA,ISO)
nucleoplasm  (ISO)

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification of a novel SNAP25 interacting protein (SIP30). Lee HK, etal., J Neurochem 2002 Jun;81(6):1338-47.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11682612   PMID:15485811   PMID:15489334   PMID:19723624   PMID:21124846   PMID:22871113   PMID:24403136   PMID:30053369  


Genomics

Comparative Map Data
Zwint
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82015,502,559 - 15,953,701 (-)NCBIGRCr8
mRatBN7.22015,938,157 - 15,953,997 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2015,938,157 - 15,953,957 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2016,649,159 - 16,664,966 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02016,004,145 - 16,019,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02016,476,752 - 16,492,559 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02017,075,781 - 17,091,715 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2017,075,771 - 17,091,766 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02019,258,272 - 19,274,238 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2017,366,344 - 17,382,150 (-)NCBICelera
Cytogenetic Map20p11NCBI
ZWINT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381056,357,227 - 56,361,273 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1056,357,227 - 56,361,273 (-)EnsemblGRCh38hg38GRCh38
GRCh371058,116,988 - 58,121,034 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361057,787,205 - 57,791,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 341057,787,204 - 57,791,040NCBI
Celera1051,380,359 - 51,384,194 (-)NCBICelera
Cytogenetic Map10q21.1NCBI
HuRef1052,100,166 - 52,104,002 (-)NCBIHuRef
CHM1_11058,399,021 - 58,402,856 (-)NCBICHM1_1
T2T-CHM13v2.01057,207,567 - 57,211,612 (-)NCBIT2T-CHM13v2.0
Zwint
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391072,490,678 - 72,510,796 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1072,490,677 - 72,510,796 (+)EnsemblGRCm39 Ensembl
GRCm381072,654,846 - 72,674,964 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1072,654,845 - 72,674,964 (+)EnsemblGRCm38mm10GRCm38
MGSCv371072,117,643 - 72,132,537 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361072,050,213 - 72,070,263 (+)NCBIMGSCv36mm8
Celera1073,721,825 - 73,736,719 (+)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1037.15NCBI
Zwint
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542510,477,331 - 10,486,288 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542510,477,224 - 10,486,372 (-)NCBIChiLan1.0ChiLan1.0
ZWINT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2868,652,375 - 68,660,157 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11068,657,697 - 68,665,829 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01052,978,892 - 52,986,797 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11055,202,564 - 55,206,450 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1055,202,383 - 55,206,450 (-)Ensemblpanpan1.1panPan2
ZWINT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12632,432,385 - 32,459,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2632,432,406 - 32,453,162 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2632,311,125 - 32,367,927 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02633,957,126 - 34,013,841 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12631,858,877 - 31,915,636 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02631,447,375 - 31,504,073 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02632,649,687 - 32,706,484 (+)NCBIUU_Cfam_GSD_1.0
Zwint
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721372,225,358 - 72,237,265 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366931,539,987 - 1,551,685 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZWINT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1494,094,894 - 94,102,060 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11494,094,781 - 94,109,447 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214102,560,703 - 102,610,775 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZWINT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1974,912,070 - 74,915,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl974,912,093 - 74,915,926 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604835,825,925 - 35,829,966 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zwint
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247917,528,426 - 7,534,553 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247917,528,452 - 7,534,182 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zwint
43 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:96
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000074404
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804241017617956Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat

Markers in Region
RH127633  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2169,587,907 - 9,588,085 (+)MAPPERmRatBN7.2
mRatBN7.22015,938,432 - 15,938,632 (+)MAPPERmRatBN7.2
Rnor_6.02017,076,057 - 17,076,256NCBIRnor6.0
Rnor_6.01610,609,508 - 10,609,685NCBIRnor6.0
Rnor_5.0168,928,049 - 8,928,226UniSTSRnor5.0
Rnor_5.02019,258,548 - 19,258,747UniSTSRnor5.0
RGSC_v3.4169,911,823 - 9,912,000UniSTSRGSC3.4
Celera2017,366,620 - 17,366,819UniSTS
RH 3.4 Map20204.1UniSTS
Cytogenetic Map16p16UniSTS
RH129520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22015,938,376 - 15,938,577 (+)MAPPERmRatBN7.2
Rnor_6.02017,076,001 - 17,076,201NCBIRnor6.0
Rnor_5.02019,258,492 - 19,258,692UniSTSRnor5.0
Celera2017,366,564 - 17,366,764UniSTS
RH 3.4 Map20201.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 62
Medium 3 43 57 41 19 41 8 11 12 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000074404   ⟹   ENSRNOP00000067414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2015,938,157 - 15,953,957 (-)Ensembl
Rnor_6.0 Ensembl2017,075,771 - 17,091,766 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100712   ⟹   ENSRNOP00000085046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2015,938,157 - 15,953,943 (-)Ensembl
RefSeq Acc Id: NM_147138   ⟹   NP_671479
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82015,937,396 - 15,953,203 (-)NCBI
mRatBN7.22015,938,157 - 15,953,964 (-)NCBI
Rnor_6.02017,075,781 - 17,091,715 (-)NCBI
Rnor_5.02019,258,272 - 19,274,238 (-)NCBI
Celera2017,366,344 - 17,382,150 (-)RGD
Sequence:
RefSeq Acc Id: XM_039098465   ⟹   XP_038954393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82015,939,848 - 15,953,701 (-)NCBI
mRatBN7.22015,951,425 - 15,953,997 (-)NCBI
RefSeq Acc Id: XM_063278987   ⟹   XP_063135057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82015,502,559 - 15,953,301 (-)NCBI
RefSeq Acc Id: NP_671479   ⟸   NM_147138
- UniProtKB: Q546Y5 (UniProtKB/Swiss-Prot),   Q8VIL3 (UniProtKB/Swiss-Prot),   A6JKM9 (UniProtKB/TrEMBL),   A0A8I6A1E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067414   ⟸   ENSRNOT00000074404
RefSeq Acc Id: XP_038954393   ⟸   XM_039098465
- Peptide Label: isoform X1
- UniProtKB: Q8VIL3 (UniProtKB/Swiss-Prot),   Q546Y5 (UniProtKB/Swiss-Prot),   A6JKM9 (UniProtKB/TrEMBL),   A0A8I6A1E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000085046   ⟸   ENSRNOT00000100712
RefSeq Acc Id: XP_063135057   ⟸   XM_063278987
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VIL3-F1-model_v2 AlphaFold Q8VIL3 1-266 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701547
Promoter ID:EPDNEW_R12071
Type:multiple initiation site
Name:Zwint_1
Description:ZW10 interacting kinetochore protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02017,091,703 - 17,091,763EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628671 AgrOrtholog
BioCyc Gene G2FUF-4077 BioCyc
Ensembl Genes ENSRNOG00000048682 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055022622 UniProtKB/Swiss-Prot
  ENSRNOG00060028638 UniProtKB/Swiss-Prot
  ENSRNOG00065023618 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074404 ENTREZGENE
  ENSRNOT00000074404.3 UniProtKB/Swiss-Prot
  ENSRNOT00000100712.1 UniProtKB/TrEMBL
  ENSRNOT00055038839 UniProtKB/Swiss-Prot
  ENSRNOT00060049909 UniProtKB/Swiss-Prot
  ENSRNOT00065040533 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.4090 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921645 IMAGE-MGC_LOAD
InterPro Zwint-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:257644 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72643 IMAGE-MGC_LOAD
NCBI Gene 257644 ENTREZGENE
PANTHER PTHR31504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZW10 INTERACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Zwint UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Zwint PhenoGen
RatGTEx ENSRNOG00000048682 RatGTEx
  ENSRNOG00055022622 RatGTEx
  ENSRNOG00060028638 RatGTEx
  ENSRNOG00065023618 RatGTEx
UniProt A0A8I6A1E2 ENTREZGENE, UniProtKB/TrEMBL
  A6JKM8_RAT UniProtKB/TrEMBL
  A6JKM9 ENTREZGENE, UniProtKB/TrEMBL
  Q546Y5 ENTREZGENE
  Q8VIL3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q546Y5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-17 Zwint  ZW10 interacting kinetochore protein  Zwint  ZW10 interactor, kinetochore protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-02 Zwint  ZW10 interactor, kinetochore protein  Zwint  ZW10 interactor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Zwint  ZW10 interactor  Sip30  SNAP25 interacting protein 30  Symbol and Name updated 1299863 APPROVED
2003-02-27 Sip30  SNAP25 interacting protein 30      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain, testis and kidney 633971
gene_physical_interaction indirectly interacts with syntaxin 633971