Gene: Jag1 (jagged canonical Notch ligand 1) Rattus norvegicus
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Symbol: Jag1
Name: jagged canonical Notch ligand 1
Description: Exhibits Notch binding activity and receptor ligand activity; involved in several processes, including Notch signaling pathway, animal organ development, and negative regulation of cell differentiation; localizes to the plasma membrane; predicted to colocalize with the membrane; orthologous to human JAG1 (jagged canonical Notch ligand 1); PARTICIPATES IN Notch signaling pathway; Alagille syndrome pathway; altered Notch signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: jagged 1; protein jagged-1
Orthologs:
Homo sapiens (human) : JAG1 (jagged canonical Notch ligand 1)  HGNC  Alliance
Mus musculus (house mouse) : Jag1 (jagged 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jag1 (jagged canonical Notch ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : JAG1 (jagged canonical Notch ligand 1)
Canis lupus familiaris (dog) : JAG1 (jagged canonical Notch ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jag1 (jagged canonical Notch ligand 1)
Sus scrofa (pig) : JAG1 (jagged canonical Notch ligand 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03130,079,361 - 130,114,781 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03136,558,688 - 136,594,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43125,181,063 - 125,216,481 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13125,086,635 - 125,122,054 (-)NCBI
Celera3123,126,087 - 123,161,497 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Jag1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2937
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.