Gene: Hes1 (hes family bHLH transcription factor 1) Rattus norvegicus
Symbol: Hes1
Name: hes family bHLH transcription factor 1
Description: ENCODES a protein that exhibits chromatin binding; DNA binding; E-box binding; INVOLVED IN cellular response to fatty acid; cellular response to interleukin-1; cellular response to nerve growth factor stimulus; PARTICIPATES IN Notch signaling pathway; maturity onset diabetes of the young pathway; Notch signaling pathway; ASSOCIATED WITH Acute Kidney Injury; Epilepsy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; FOUND IN chromatin; nuclear matrix; cytoplasm (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene
Type: protein-coding
Also known as: hairy and enhancer of split 1; hairy and enhancer of split 1 (Drosophila); hairy and enhancer of split 1, (Drosophila) ; hairy-like protein; RHL; transcription factor HES-1
Homo sapiens (human) : HES1 (hes family bHLH transcription factor 1)  HGNC  AGR
Mus musculus (house mouse) : Hes1 (hes family bHLH transcription factor 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Hes1 (hes family bHLH transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HES1 (hes family bHLH transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hes1 (hes family bHLH transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01174,312,837 - 74,315,249 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01177,360,109 - 77,362,521 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,603,482 - 72,605,673 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11172,661,439 - 72,663,801 (-)NCBI
Celera1169,677,011 - 69,679,422 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hes1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62081
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE