(-)-epigallocatechin 3-gallate multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of INSIG1 mRNA CTD PMID:22079256 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of INSIG1 mRNA CTD PMID:26776438 (S)-nicotine increases expression ISO INSIG1 (Homo sapiens) 6480464 Nicotine results in increased expression of INSIG1 mRNA CTD PMID:23416264 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine increases expression EXP 6480464 chlorcyclizine results in increased expression of INSIG1 mRNA CTD PMID:21058326 1-benzylpiperazine increases expression EXP 6480464 N-benzylpiperazine results in increased expression of INSIG1 mRNA CTD PMID:26821219 1-naphthyl isothiocyanate multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of INSIG1 mRNA CTD PMID:27344345 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of INSIG1 mRNA CTD PMID:30723492 17alpha-ethynylestradiol multiple interactions ISO Insig1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of INSIG1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of INSIG1 mRNA CTD PMID:20170705 and PMID:26865667 17alpha-ethynylestradiol affects expression ISO INSIG1 (Homo sapiens) 6480464 Ethinyl Estradiol affects the expression of INSIG1 mRNA CTD PMID:20170705 and PMID:26865667 17alpha-ethynylestradiol increases expression ISO INSIG1 (Homo sapiens) 6480464 Ethinyl Estradiol results in increased expression of INSIG1 mRNA CTD PMID:18936297 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of INSIG1 mRNA CTD PMID:15901920 and PMID:17108234 17beta-estradiol affects expression ISO INSIG1 (Homo sapiens) 6480464 Estradiol affects the expression of INSIG1 mRNA CTD PMID:21826169 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of INSIG1 mRNA CTD PMID:32145629 17beta-estradiol decreases expression ISO Insig1 (Mus musculus) 6480464 Estradiol results in decreased expression of INSIG1 mRNA CTD PMID:19484750 17beta-estradiol increases expression ISO INSIG1 (Homo sapiens) 6480464 Estradiol results in increased expression of INSIG1 mRNA CTD PMID:19167446 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO INSIG1 (Homo sapiens) 6480464 Metribolone results in increased expression of INSIG1 mRNA and Metribolone results in increased expression of INSIG1 protein CTD PMID:16751804 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO INSIG1 (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of INSIG1 mRNA CTD PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Insig1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Insig1 (Mus musculus) 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO INSIG1 (Homo sapiens) 6480464 2 more ... CTD PMID:31173147 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Insig1 (Mus musculus) 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO INSIG1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of INSIG1 mRNA CTD PMID:12377990 and PMID:16704738 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of INSIG1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of INSIG1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Insig1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of INSIG1 mRNA CTD PMID:21570461 and PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of INSIG1 mRNA CTD PMID:20558275 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO INSIG1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of INSIG1 mRNA CTD PMID:21998131 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Insig1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of INSIG1 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Insig1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 and PMID:28433925 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of INSIG1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of INSIG1 mRNA CTD PMID:21346803 2-butoxyethanol increases expression ISO Insig1 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of INSIG1 mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression ISO INSIG1 (Homo sapiens) 6480464 Lactic Acid results in increased expression of INSIG1 mRNA CTD PMID:30851411 2-methylcholine affects expression ISO INSIG1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of INSIG1 mRNA CTD PMID:21179406 25-hydroxycholesterol decreases expression ISO Insig1 (Mus musculus) 6480464 25-hydroxycholesterol results in decreased expression of INSIG1 mRNA CTD PMID:19260826 3,3',4,4',5-pentachlorobiphenyl increases expression ISO INSIG1 (Homo sapiens) 6480464 3 more ... CTD PMID:23146750 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Insig1 (Mus musculus) 6480464 3 more ... CTD PMID:29216392 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of INSIG1 mRNA CTD PMID:15953391 3-phenylprop-2-enal decreases expression ISO INSIG1 (Homo sapiens) 6480464 cinnamaldehyde results in decreased expression of INSIG1 mRNA CTD PMID:17178418 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of INSIG1 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol decreases expression ISO Insig1 (Mus musculus) 6480464 bisphenol S results in decreased expression of INSIG1 mRNA CTD PMID:33297965 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of INSIG1 mRNA CTD PMID:36041667 5-aza-2'-deoxycytidine decreases expression ISO INSIG1 (Homo sapiens) 6480464 Decitabine results in decreased expression of INSIG1 mRNA CTD PMID:19194470 5-fluorouracil increases expression ISO INSIG1 (Homo sapiens) 6480464 Fluorouracil results in increased expression of INSIG1 mRNA CTD PMID:17039268 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of INSIG1 mRNA CTD PMID:24780913 and PMID:25825206 7,12-dimethyltetraphene affects expression ISO Insig1 (Mus musculus) 6480464 9 more ... CTD PMID:21785161 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:12376462 8-Br-cAMP increases expression ISO INSIG1 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of INSIG1 mRNA CTD PMID:22079614 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of INSIG1 mRNA CTD PMID:31881176 acetylsalicylic acid increases expression ISO INSIG1 (Homo sapiens) 6480464 Aspirin results in increased expression of INSIG1 mRNA CTD PMID:15928584 acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of INSIG1 mRNA CTD PMID:12800193 acrylamide decreases expression ISO INSIG1 (Homo sapiens) 6480464 Acrylamide results in decreased expression of INSIG1 mRNA CTD PMID:32763439 aflatoxin B1 affects expression ISO INSIG1 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of INSIG1 protein CTD PMID:20106945 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of INSIG1 mRNA CTD PMID:33354967 aflatoxin B1 decreases expression ISO INSIG1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of INSIG1 mRNA CTD PMID:27153756 and PMID:32234424 aflatoxin B1 decreases methylation ISO INSIG1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of INSIG1 gene CTD PMID:27153756 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of INSIG1 mRNA CTD PMID:23630614 aflatoxin B1 decreases expression ISO Insig1 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of INSIG1 mRNA CTD PMID:19770486 Alisol A multiple interactions EXP 6480464 [alisol A co-treated with alisol A 24-acetate co-treated with alisol B co-treated with alisol B 23-acetate co-treated with alisol C 23-acetate co-treated with alisol F co-treated with alisol F 24-acetate] results in increased expression of INSIG1 mRNA CTD PMID:33035272 Alisol B multiple interactions EXP 6480464 [alisol A co-treated with alisol A 24-acetate co-treated with alisol B co-treated with alisol B 23-acetate co-treated with alisol C 23-acetate co-treated with alisol F co-treated with alisol F 24-acetate] results in increased expression of INSIG1 mRNA CTD PMID:33035272 Alisol C 23-acetate multiple interactions EXP 6480464 [alisol A co-treated with alisol A 24-acetate co-treated with alisol B co-treated with alisol B 23-acetate co-treated with alisol C 23-acetate co-treated with alisol F co-treated with alisol F 24-acetate] results in increased expression of INSIG1 mRNA CTD PMID:33035272 all-trans-retinoic acid multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Tretinoin co-treated with arsenic trioxide] results in decreased expression of INSIG1 mRNA CTD PMID:15894607 all-trans-retinoic acid increases expression ISO INSIG1 (Homo sapiens) 6480464 Tretinoin results in increased expression of INSIG1 mRNA CTD PMID:33167477 all-trans-retinoic acid decreases expression ISO INSIG1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of INSIG1 mRNA CTD PMID:15894607 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of INSIG1 mRNA CTD PMID:16483693 amphotericin B increases expression ISO INSIG1 (Homo sapiens) 6480464 Amphotericin B analog results in increased expression of INSIG1 mRNA and Amphotericin B results in increased expression of INSIG1 mRNA CTD PMID:28534445 antimycin A increases expression ISO INSIG1 (Homo sapiens) 6480464 Antimycin A results in increased expression of INSIG1 mRNA CTD PMID:33512557 Archazolid B increases expression ISO INSIG1 (Homo sapiens) 6480464 archazolid B results in increased expression of INSIG1 mRNA CTD PMID:25218289 aristolochic acid A decreases expression ISO INSIG1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of INSIG1 mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO Insig1 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of INSIG1 mRNA CTD PMID:23650126 arsenous acid decreases expression ISO INSIG1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of INSIG1 mRNA CTD PMID:15894607 arsenous acid multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of INSIG1 mRNA CTD PMID:15894607 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of INSIG1 mRNA CTD PMID:36841081 avobenzone increases expression ISO INSIG1 (Homo sapiens) 6480464 avobenzone results in increased expression of INSIG1 mRNA CTD PMID:31016361 azoxystrobin affects expression ISO INSIG1 (Homo sapiens) 6480464 azoxystrobin affects the expression of INSIG1 mRNA CTD PMID:33512557 beauvericin increases expression ISO INSIG1 (Homo sapiens) 6480464 beauvericin results in increased expression of INSIG1 mRNA CTD PMID:29203277 benzalkonium chloride increases expression ISO Insig1 (Mus musculus) 6480464 Benzalkonium Compounds results in increased expression of INSIG1 mRNA CTD PMID:31199489 benzene affects expression EXP 6480464 Benzene affects the expression of INSIG1 mRNA CTD PMID:15878777 benzo[a]pyrene increases expression ISO Insig1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of INSIG1 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO INSIG1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of INSIG1 mRNA CTD PMID:32234424 benzo[a]pyrene affects expression ISO Insig1 (Mus musculus) 6480464 Benzo(a)pyrene affects the expression of INSIG1 mRNA CTD PMID:22342234 benzo[a]pyrene multiple interactions ISO Insig1 (Mus musculus) 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of INSIG1 mRNA] CTD PMID:22228805 benzo[a]pyrene diol epoxide I affects expression ISO INSIG1 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of INSIG1 mRNA CTD PMID:16648578 bezafibrate increases expression ISO Insig1 (Mus musculus) 6480464 Bezafibrate results in increased expression of INSIG1 mRNA CTD PMID:17118139 and PMID:19124612 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of INSIG1 mRNA CTD PMID:15728792 and PMID:33983380 bis(2-ethylhexyl) phthalate multiple interactions ISO Insig1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A affects expression ISO Insig1 (Mus musculus) 6480464 bisphenol A affects the expression of INSIG1 mRNA CTD PMID:21932408 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of INSIG1 mRNA CTD PMID:36041667 bisphenol A decreases methylation ISO INSIG1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of INSIG1 promoter CTD PMID:30352284 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of INSIG1 mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO Insig1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of INSIG1 mRNA CTD PMID:30816183 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of INSIG1 mRNA CTD PMID:12075121 more ... bisphenol A increases expression ISO INSIG1 (Homo sapiens) 6480464 bisphenol A results in increased expression of INSIG1 mRNA CTD PMID:25047013 and PMID:29275510 bisphenol A affects expression ISO INSIG1 (Homo sapiens) 6480464 bisphenol A affects the expression of INSIG1 mRNA CTD PMID:20170705 and PMID:21826169 bisphenol A increases expression ISO Insig1 (Mus musculus) 6480464 bisphenol A results in increased expression of INSIG1 mRNA CTD PMID:21932408 and PMID:25270620 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of INSIG1 mRNA CTD PMID:36041667 bleomycin A2 multiple interactions ISO Insig1 (Mus musculus) 6480464 Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] and lenabasum inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] CTD PMID:30825431 bleomycin A2 decreases expression ISO Insig1 (Mus musculus) 6480464 Bleomycin results in decreased expression of INSIG1 mRNA CTD PMID:30825431 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of INSIG1 mRNA CTD PMID:32479839 butan-1-ol multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of INSIG1 mRNA CTD PMID:29432896 Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:15728792 butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of INSIG1 mRNA CTD PMID:12800193 butyric acid increases expression ISO INSIG1 (Homo sapiens) 6480464 Butyric Acid results in increased expression of INSIG1 mRNA CTD PMID:34581912 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of INSIG1 mRNA CTD PMID:19010381 cadmium dichloride increases expression ISO INSIG1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of INSIG1 mRNA CTD PMID:25596134 cadmium sulfate multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of INSIG1 mRNA CTD PMID:18654764 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of INSIG1 mRNA CTD PMID:20864626 and PMID:25868845 calcitriol multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of INSIG1 mRNA CTD PMID:21592394 calcitriol increases expression ISO INSIG1 (Homo sapiens) 6480464 Calcitriol results in increased expression of INSIG1 mRNA CTD PMID:21592394 cannabidiol multiple interactions ISO Insig1 (Mus musculus) 6480464 Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] CTD PMID:30825431 captan increases expression ISO Insig1 (Mus musculus) 6480464 Captan results in increased expression of INSIG1 mRNA CTD PMID:31558096 carbamazepine affects expression ISO INSIG1 (Homo sapiens) 6480464 Carbamazepine affects the expression of INSIG1 mRNA CTD PMID:25979313 carbon nanotube increases expression ISO INSIG1 (Homo sapiens) 6480464 Nanotubes and Carbon results in increased expression of INSIG1 mRNA CTD PMID:24389112 carbon nanotube decreases expression ISO Insig1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 carmustine decreases expression ISO INSIG1 (Homo sapiens) 6480464 Carmustine results in decreased expression of INSIG1 mRNA CTD PMID:15980968 celastrol increases expression ISO INSIG1 (Homo sapiens) 6480464 celastrol results in increased expression of INSIG1 mRNA CTD PMID:17010675 chloroacetaldehyde increases expression ISO INSIG1 (Homo sapiens) 6480464 chloroacetaldehyde results in increased expression of INSIG1 mRNA CTD PMID:25596134 chloroethene increases expression ISO Insig1 (Mus musculus) 6480464 Vinyl Chloride results in increased expression of INSIG1 mRNA CTD PMID:18579281 chromium(6+) decreases expression ISO INSIG1 (Homo sapiens) 6480464 chromium hexavalent ion results in decreased expression of INSIG1 mRNA CTD PMID:30690063 cidofovir anhydrous increases expression ISO INSIG1 (Homo sapiens) 6480464 Cidofovir results in increased expression of INSIG1 mRNA CTD PMID:25596134 ciguatoxin CTX1B affects expression ISO Insig1 (Mus musculus) 6480464 Ciguatoxins affects the expression of INSIG1 mRNA CTD PMID:18353800 cisplatin multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of INSIG1 mRNA and Cisplatin affects the reaction [Piroxicam results in decreased expression of INSIG1 mRNA] CTD PMID:21858171 and PMID:27392435 cisplatin decreases expression ISO INSIG1 (Homo sapiens) 6480464 Cisplatin results in decreased expression of INSIG1 mRNA CTD PMID:27594783 clobetasol increases expression ISO Insig1 (Mus musculus) 6480464 Clobetasol results in increased expression of INSIG1 mRNA CTD PMID:27462272 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of INSIG1 mRNA CTD PMID:12851107 and PMID:17126302 cobalt dichloride multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of INSIG1 mRNA CTD PMID:18654764 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of INSIG1 mRNA CTD PMID:24386269 cobalt dichloride increases expression ISO INSIG1 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of INSIG1 mRNA CTD PMID:19376846 colforsin daropate hydrochloride multiple interactions ISO INSIG1 (Homo sapiens) 6480464 AR protein promotes the reaction [Colforsin results in increased expression of INSIG1 protein] CTD PMID:16751804 colforsin daropate hydrochloride increases expression ISO INSIG1 (Homo sapiens) 6480464 Colforsin results in increased expression of INSIG1 mRNA and Colforsin results in increased expression of INSIG1 protein CTD PMID:16751804 copper atom multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA and [NSC 689534 binds to Copper] which results in increased expression of INSIG1 mRNA CTD PMID:20971185 and PMID:24690739 copper atom decreases expression EXP 6480464 Copper results in decreased expression of INSIG1 mRNA CTD PMID:30556269 copper(0) multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA and [NSC 689534 binds to Copper] which results in increased expression of INSIG1 mRNA CTD PMID:20971185 and PMID:24690739 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of INSIG1 mRNA CTD PMID:30556269 copper(II) sulfate increases expression ISO INSIG1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of INSIG1 mRNA CTD PMID:19549813 coumestrol increases expression ISO INSIG1 (Homo sapiens) 6480464 Coumestrol results in increased expression of INSIG1 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 crizotinib increases expression ISO INSIG1 (Homo sapiens) 6480464 crizotinib results in increased expression of INSIG1 mRNA CTD PMID:23707608 CU-O LINKAGE increases expression ISO INSIG1 (Homo sapiens) 6480464 cupric oxide results in increased expression of INSIG1 mRNA CTD PMID:22077320 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of INSIG1 mRNA CTD PMID:27523638 cyclosporin A decreases expression ISO INSIG1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of INSIG1 mRNA CTD PMID:20106945 cyclosporin A increases expression ISO INSIG1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of INSIG1 mRNA CTD PMID:25596134 more ... cyclosporin A multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of INSIG1 mRNA CTD PMID:27344345 cylindrospermopsin decreases expression ISO INSIG1 (Homo sapiens) 6480464 cylindrospermopsin results in decreased expression of INSIG1 mRNA CTD PMID:24921660 cyproconazole increases expression ISO Insig1 (Mus musculus) 6480464 cyproconazole results in increased expression of INSIG1 mRNA CTD PMID:22045034 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of INSIG1 mRNA CTD PMID:23640034 desmosterol decreases expression ISO Insig1 (Mus musculus) 6480464 Desmosterol results in decreased expression of INSIG1 protein CTD PMID:19260826 dexamethasone decreases expression ISO Insig1 (Mus musculus) 6480464 Dexamethasone results in decreased expression of INSIG1 mRNA CTD PMID:22733784 Di-n-hexyl phthalate decreases expression EXP 6480464 di-n-hexyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:33983380 diarsenic trioxide multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of INSIG1 mRNA CTD PMID:15894607 diarsenic trioxide decreases expression ISO INSIG1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of INSIG1 mRNA CTD PMID:15894607 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of INSIG1 mRNA CTD PMID:15728792 more ... Dicyclohexyl phthalate decreases expression EXP 6480464 dicyclohexyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:33983380 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of INSIG1 mRNA CTD PMID:37077353 diisobutyl phthalate decreases expression EXP 6480464 diisobutyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:33983380 diisononyl phthalate decreases expression EXP 6480464 diisononyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:33983380 dimethylarsinic acid multiple interactions ISO Insig1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of INSIG1 mRNA CTD PMID:34876320 dimethylselenide multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in decreased expression of INSIG1-DT mRNA] which results in decreased expression of INSIG1 mRNA CTD PMID:33656867 dioxygen increases expression ISO INSIG1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of INSIG1 mRNA CTD PMID:25596134 dipentyl phthalate decreases expression EXP 6480464 di-n-pentyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:15728792 and PMID:33983380 disulfiram multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA CTD PMID:24690739 dorsomorphin multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO INSIG1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of INSIG1 mRNA CTD PMID:29803840 endosulfan affects expression EXP 6480464 Endosulfan affects the expression of INSIG1 mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of INSIG1 mRNA CTD PMID:19167446 entinostat decreases expression ISO INSIG1 (Homo sapiens) 6480464 entinostat results in decreased expression of INSIG1 mRNA CTD PMID:27188386 epoxiconazole decreases expression ISO Insig1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of INSIG1 mRNA CTD PMID:35436446 ethanol multiple interactions EXP 6480464 [Fish Oils co-treated with Ethanol] results in increased expression of INSIG1 mRNA CTD PMID:17347304 ethanol affects expression ISO Insig1 (Mus musculus) 6480464 Ethanol affects the expression of INSIG1 mRNA CTD PMID:30319688 ethanol multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of INSIG1 mRNA CTD PMID:29432896 ethyl methanesulfonate decreases expression ISO INSIG1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of INSIG1 mRNA CTD PMID:23649840 etoposide affects response to substance ISO INSIG1 (Homo sapiens) 6480464 INSIG1 protein affects the susceptibility to Etoposide CTD PMID:16217747 fenofibrate decreases expression ISO INSIG1 (Homo sapiens) 6480464 Fenofibrate results in decreased expression of INSIG1 mRNA CTD PMID:25572481 fluoranthene decreases expression ISO Insig1 (Mus musculus) 6480464 fluoranthene results in decreased expression of INSIG1 mRNA CTD PMID:28329830 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of INSIG1 mRNA CTD PMID:21852994 fluoxetine increases expression ISO INSIG1 (Homo sapiens) 6480464 Fluoxetine results in increased expression of INSIG1 mRNA CTD PMID:37386098 flusilazole affects expression ISO Insig1 (Mus musculus) 6480464 flusilazole affects the expression of INSIG1 mRNA CTD PMID:21195148 and PMID:22634333 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of INSIG1 mRNA CTD PMID:24136188 folic acid increases expression ISO INSIG1 (Homo sapiens) 6480464 Folic Acid results in increased expression of INSIG1 mRNA CTD PMID:11723236 folic acid decreases expression ISO Insig1 (Mus musculus) 6480464 Folic Acid results in decreased expression of INSIG1 mRNA CTD PMID:25629700 formaldehyde decreases expression ISO INSIG1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of INSIG1 mRNA CTD PMID:23649840 fructose decreases expression ISO Insig1 (Mus musculus) 6480464 Fructose results in decreased expression of INSIG1 protein CTD PMID:22698815 fructose increases expression ISO Insig1 (Mus musculus) 6480464 Fructose results in increased expression of INSIG1 mRNA CTD PMID:22698815 fructose multiple interactions ISO Insig1 (Mus musculus) 6480464 Phenylbutyrates inhibits the reaction [Fructose results in decreased expression of INSIG1 protein] CTD PMID:22698815 furan increases expression ISO Insig1 (Mus musculus) 6480464 furan results in increased expression of INSIG1 mRNA CTD PMID:24183702 and PMID:24910943 Ganoderic acid A decreases expression ISO INSIG1 (Homo sapiens) 6480464 ganoderic acid A results in decreased expression of INSIG1 mRNA CTD PMID:29852127 gedunin increases expression ISO INSIG1 (Homo sapiens) 6480464 gedunin results in increased expression of INSIG1 mRNA CTD PMID:17010675 gemcitabine increases expression ISO INSIG1 (Homo sapiens) 6480464 Gemcitabine results in increased expression of INSIG1 mRNA CTD PMID:17039268 genistein increases expression ISO INSIG1 (Homo sapiens) 6480464 Genistein results in increased expression of INSIG1 mRNA CTD PMID:18847459 and PMID:26865667 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of INSIG1 mRNA CTD PMID:33387578 GW 3965 increases expression ISO INSIG1 (Homo sapiens) 6480464 GW 3965 results in increased expression of INSIG1 mRNA CTD PMID:31437187 GW 7647 increases expression ISO INSIG1 (Homo sapiens) 6480464 GW 7647 results in increased expression of INSIG1 mRNA CTD PMID:31437187 hexaconazole affects expression ISO Insig1 (Mus musculus) 6480464 hexaconazole affects the expression of INSIG1 mRNA CTD PMID:21195148 hydrogen peroxide multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 hydrogen peroxide decreases expression ISO INSIG1 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of INSIG1 mRNA CTD PMID:34581912 hydroxyl multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in decreased expression of INSIG1-DT mRNA] which results in decreased expression of INSIG1 mRNA CTD PMID:33656867 ibuprofen increases expression ISO INSIG1 (Homo sapiens) 6480464 Ibuprofen results in increased expression of INSIG1 mRNA CTD PMID:25596134 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of INSIG1 mRNA CTD PMID:22129741 irinotecan decreases expression ISO INSIG1 (Homo sapiens) 6480464 Irinotecan analog results in decreased expression of INSIG1 mRNA CTD PMID:18927307 iron dichloride increases expression ISO INSIG1 (Homo sapiens) 6480464 ferrous chloride results in increased expression of INSIG1 mRNA CTD PMID:35984750 isobutanol multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of INSIG1 mRNA CTD PMID:29432896 isoflavones affects expression ISO INSIG1 (Homo sapiens) 6480464 Isoflavones affects the expression of INSIG1 mRNA CTD PMID:16365062 isoflavones increases expression ISO INSIG1 (Homo sapiens) 6480464 Isoflavones results in increased expression of INSIG1 mRNA CTD PMID:17374662 isotretinoin decreases expression ISO INSIG1 (Homo sapiens) 6480464 Isotretinoin results in decreased expression of INSIG1 mRNA CTD PMID:20436886 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of INSIG1 mRNA CTD PMID:37077353 lead(II) chloride multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of INSIG1 mRNA CTD PMID:18654764 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of INSIG1 mRNA CTD PMID:24136188 linalool increases expression ISO Insig1 (Mus musculus) 6480464 linalool results in increased expression of INSIG1 protein CTD PMID:21944868 linalool increases expression ISO INSIG1 (Homo sapiens) 6480464 linalool results in increased expression of INSIG1 protein CTD PMID:21944868 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of INSIG1 mRNA CTD PMID:16415329 lipopolysaccharide multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of INSIG1 mRNA more ... CTD PMID:35811015 and PMID:35877022 lipopolysaccharide increases expression ISO INSIG1 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of INSIG1 mRNA CTD PMID:35811015 lipopolysaccharide multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG1 mRNA] CTD PMID:16415329 lovastatin increases expression ISO INSIG1 (Homo sapiens) 6480464 Lovastatin results in increased expression of INSIG1 mRNA CTD PMID:19260826 lovastatin multiple interactions ISO Insig1 (Mus musculus) 6480464 [Dietary Fats co-treated with Lovastatin] affects the expression of INSIG1 mRNA CTD PMID:29852127 lovastatin increases expression ISO Insig1 (Mus musculus) 6480464 Lovastatin results in increased expression of INSIG1 mRNA CTD PMID:19260826 maneb multiple interactions ISO Insig1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of INSIG1 mRNA CTD PMID:36117858 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of INSIG1 mRNA CTD PMID:28801915 manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of INSIG1 gene CTD PMID:28801915 mercury dibromide decreases expression ISO INSIG1 (Homo sapiens) 6480464 mercuric bromide results in decreased expression of INSIG1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of INSIG1 mRNA CTD PMID:27188386 metformin increases expression ISO Insig1 (Mus musculus) 6480464 Metformin results in increased expression of INSIG1 mRNA CTD PMID:23457588 methyl methanesulfonate decreases expression ISO INSIG1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of INSIG1 mRNA CTD PMID:23649840 methylarsonic acid multiple interactions ISO Insig1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of INSIG1 mRNA CTD PMID:34876320 methylmercury chloride decreases expression ISO Insig1 (Mus musculus) 6480464 methylmercuric chloride results in decreased expression of INSIG1 mRNA CTD PMID:19465457 methylmercury chloride decreases expression ISO INSIG1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of INSIG1 mRNA CTD PMID:27188386 miconazole increases expression ISO Insig1 (Mus musculus) 6480464 Miconazole results in increased expression of INSIG1 mRNA CTD PMID:27462272 microcystin-LR increases expression ISO Insig1 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of INSIG1 mRNA CTD PMID:17383702 N-acetyl-L-cysteine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of INSIG1 mRNA CTD PMID:22129741 N-ethyl-N-nitrosourea decreases expression EXP 6480464 Ethylnitrosourea results in decreased expression of INSIG1 mRNA CTD PMID:15954086 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of INSIG1 mRNA CTD PMID:28801915 N-nitrosodiethylamine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of INSIG1 mRNA CTD PMID:22129741 N-nitrosomorpholine decreases expression EXP 6480464 N-nitrosomorpholine results in decreased expression of INSIG1 mRNA CTD PMID:19716841 N-Nitrosopyrrolidine decreases expression ISO INSIG1 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of INSIG1 mRNA CTD PMID:32234424 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG1 mRNA] CTD PMID:16415329 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of INSIG1 mRNA CTD PMID:24136188 nickel atom increases expression ISO INSIG1 (Homo sapiens) 6480464 Nickel results in increased expression of INSIG1 mRNA CTD PMID:23195993 nickel atom decreases expression ISO INSIG1 (Homo sapiens) 6480464 Nickel results in decreased expression of INSIG1 mRNA CTD PMID:24768652 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of INSIG1 mRNA CTD PMID:26776438 nicotine increases expression ISO INSIG1 (Homo sapiens) 6480464 Nicotine results in increased expression of INSIG1 mRNA CTD PMID:23416264 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of INSIG1 mRNA CTD PMID:33484710 O-methyleugenol decreases expression ISO INSIG1 (Homo sapiens) 6480464 methyleugenol results in decreased expression of INSIG1 mRNA CTD PMID:32234424 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of INSIG1 mRNA CTD PMID:25729387 oxaliplatin decreases expression ISO INSIG1 (Homo sapiens) 6480464 oxaliplatin results in decreased expression of INSIG1 mRNA CTD PMID:16510598 p-chloromercuribenzoic acid decreases expression ISO INSIG1 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of INSIG1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of INSIG1 mRNA CTD PMID:27188386 paclitaxel affects response to substance ISO INSIG1 (Homo sapiens) 6480464 INSIG1 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 paracetamol increases expression ISO Insig1 (Mus musculus) 6480464 Acetaminophen results in increased expression of INSIG1 mRNA CTD PMID:17585979 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of INSIG1 mRNA CTD PMID:30723492 paracetamol decreases expression ISO INSIG1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of INSIG1 mRNA CTD PMID:29067470 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of INSIG1 mRNA CTD PMID:22112502 and PMID:33387578 paraquat increases expression EXP 6480464 Paraquat results in increased expression of INSIG1 mRNA CTD PMID:32680482 paraquat multiple interactions ISO Insig1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of INSIG1 mRNA CTD PMID:36117858 perfluorononanoic acid decreases expression ISO INSIG1 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of INSIG1 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of INSIG1 mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid decreases expression ISO INSIG1 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of INSIG1 mRNA CTD PMID:32588087 and PMID:36864359 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of INSIG1 mRNA CTD PMID:19162173 perfluorooctanoic acid decreases expression ISO Insig1 (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of INSIG1 protein CTD PMID:25092180 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of INSIG1 mRNA CTD PMID:31324951 phenobarbital decreases expression ISO Insig1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of INSIG1 mRNA CTD PMID:19270015 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of INSIG1 mRNA CTD PMID:19162173 phenylmercury acetate decreases expression ISO INSIG1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of INSIG1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of INSIG1 mRNA CTD PMID:27188386 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of INSIG1 mRNA CTD PMID:12376462 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of INSIG1 protein CTD PMID:19248225 pirinixic acid decreases expression ISO Insig1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of INSIG1 mRNA CTD PMID:23811191 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of INSIG1 mRNA CTD PMID:17126302 and PMID:19162173 pirinixic acid increases expression ISO Insig1 (Mus musculus) 6480464 pirinixic acid results in increased expression of INSIG1 mRNA CTD PMID:17118139 piroxicam multiple interactions ISO INSIG1 (Homo sapiens) 6480464 Cisplatin affects the reaction [Piroxicam results in decreased expression of INSIG1 mRNA] CTD PMID:21858171 piroxicam decreases expression ISO INSIG1 (Homo sapiens) 6480464 Piroxicam results in decreased expression of INSIG1 mRNA CTD PMID:21858171 potassium chromate multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of INSIG1 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO INSIG1 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of INSIG1 mRNA CTD PMID:22079256 and PMID:22714537 pregnenolone 16alpha-carbonitrile decreases expression ISO Insig1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of INSIG1 mRNA CTD PMID:28903501 progesterone increases expression ISO INSIG1 (Homo sapiens) 6480464 Progesterone results in increased expression of INSIG1 mRNA CTD PMID:18070364 propiconazole increases expression ISO INSIG1 (Homo sapiens) 6480464 propiconazole results in increased expression of INSIG1 mRNA CTD PMID:30989312 propiconazole multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [propiconazole co-treated with tebuconazole] results in increased expression of INSIG1 mRNA CTD PMID:30989312 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 rac-lactic acid increases expression ISO INSIG1 (Homo sapiens) 6480464 Lactic Acid results in increased expression of INSIG1 mRNA CTD PMID:30851411 raloxifene increases expression ISO INSIG1 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in increased expression of INSIG1 mRNA CTD PMID:16497877 ranitidine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of INSIG1 mRNA] CTD PMID:16415329 resveratrol multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of INSIG1 mRNA CTD PMID:19167446 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of INSIG1 mRNA CTD PMID:28374803 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of INSIG1 mRNA CTD PMID:35811015 sarin increases expression ISO INSIG1 (Homo sapiens) 6480464 Sarin results in increased expression of INSIG1 mRNA CTD PMID:19522546 sarin decreases expression ISO INSIG1 (Homo sapiens) 6480464 Sarin results in decreased expression of INSIG1 mRNA CTD PMID:19522546 SB 431542 multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide increases expression ISO INSIG1 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of INSIG1 mRNA and Silicon Dioxide results in increased expression of INSIG1 mRNA CTD PMID:23806026 and PMID:25351596 sirolimus multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [(+)-JQ1 compound co-treated with Sirolimus] affects the expression of INSIG1 mRNA CTD PMID:25307878 sodium arsenate multiple interactions ISO Insig1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of INSIG1 mRNA CTD PMID:34876320 sodium arsenite decreases expression ISO INSIG1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of INSIG1 mRNA CTD PMID:12679051 sodium arsenite multiple interactions ISO Insig1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of INSIG1 mRNA CTD PMID:34876320 sodium arsenite increases expression ISO INSIG1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of INSIG1 mRNA CTD PMID:16966095 more ... sodium dichromate increases expression ISO Insig1 (Mus musculus) 6480464 sodium bichromate results in increased expression of INSIG1 mRNA CTD PMID:31558096 starch multiple interactions EXP 6480464 Starch analog inhibits the reaction [Rapeseed Oil metabolite results in decreased expression of INSIG1 mRNA] CTD PMID:27363782 streptozocin multiple interactions ISO Insig1 (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of INSIG1 mRNA CTD PMID:33359794 succimer multiple interactions ISO Insig1 (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of INSIG1 mRNA CTD PMID:21641980 sulindac sulfide decreases expression ISO INSIG1 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of INSIG1 mRNA CTD PMID:12734198 sunitinib increases expression ISO INSIG1 (Homo sapiens) 6480464 Sunitinib results in increased expression of INSIG1 mRNA CTD PMID:31533062 T-2 toxin decreases expression ISO INSIG1 (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of INSIG1 mRNA CTD PMID:34581912 tebuconazole multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [propiconazole co-treated with tebuconazole] results in increased expression of INSIG1 mRNA CTD PMID:30989312 tebuconazole increases expression ISO INSIG1 (Homo sapiens) 6480464 tebuconazole results in increased expression of INSIG1 mRNA CTD PMID:30458266 and PMID:30989312 tebufenpyrad increases expression ISO INSIG1 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of INSIG1 mRNA CTD PMID:33512557 temozolomide decreases expression ISO INSIG1 (Homo sapiens) 6480464 Temozolomide results in decreased expression of INSIG1 mRNA CTD PMID:31758290 tert-butyl hydroperoxide decreases expression ISO INSIG1 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of INSIG1 mRNA CTD PMID:15336504 testosterone multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of INSIG1 mRNA CTD PMID:21592394 testosterone increases expression ISO INSIG1 (Homo sapiens) 6480464 Testosterone results in increased expression of INSIG1 mRNA CTD PMID:21592394 tetrachloroethene decreases expression ISO INSIG1 (Homo sapiens) 6480464 Tetrachloroethylene results in decreased expression of INSIG1 mRNA CTD PMID:16010555 tetrachloroethene increases expression ISO Insig1 (Mus musculus) 6480464 Tetrachloroethylene results in increased expression of INSIG1 mRNA CTD PMID:28973375 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of INSIG1 mRNA CTD PMID:16239168 tetrachloromethane decreases expression ISO Insig1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of INSIG1 mRNA CTD PMID:27339419 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of INSIG1 mRNA CTD PMID:22112502 thapsigargin decreases expression ISO INSIG1 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of INSIG1 mRNA CTD PMID:22378314 thapsigargin increases expression ISO INSIG1 (Homo sapiens) 6480464 Thapsigargin results in increased expression of INSIG1 mRNA CTD PMID:29453283 thimerosal decreases expression ISO INSIG1 (Homo sapiens) 6480464 Thimerosal results in decreased expression of INSIG1 mRNA CTD PMID:27188386 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of INSIG1 mRNA CTD PMID:34492290 titanium dioxide increases expression ISO Insig1 (Mus musculus) 6480464 titanium dioxide results in increased expression of INSIG1 mRNA CTD PMID:29264374 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of INSIG1 mRNA CTD PMID:25729387 topotecan affects response to substance ISO INSIG1 (Homo sapiens) 6480464 INSIG1 protein affects the susceptibility to Topotecan CTD PMID:16217747 triadimefon affects expression ISO Insig1 (Mus musculus) 6480464 triadimefon affects the expression of INSIG1 mRNA CTD PMID:21195148 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of INSIG1 mRNA CTD PMID:33387578 trichostatin A affects expression ISO INSIG1 (Homo sapiens) 6480464 trichostatin A affects the expression of INSIG1 mRNA CTD PMID:28542535 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of INSIG1 mRNA CTD PMID:30589522 Triptolide decreases expression ISO Insig1 (Mus musculus) 6480464 triptolide results in decreased expression of INSIG1 mRNA CTD PMID:32835833 troglitazone multiple interactions EXP 6480464 [troglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of INSIG1 protein CTD PMID:19248225 troglitazone decreases expression ISO INSIG1 (Homo sapiens) 6480464 troglitazone results in decreased expression of INSIG1 mRNA CTD PMID:25572481 tunicamycin decreases expression ISO INSIG1 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of INSIG1 mRNA CTD PMID:22378314 and PMID:29453283 uranium atom affects expression ISO INSIG1 (Homo sapiens) 6480464 Uranium affects the expression of INSIG1 mRNA CTD PMID:15672453 valproic acid affects expression ISO Insig1 (Mus musculus) 6480464 Valproic Acid affects the expression of INSIG1 mRNA CTD PMID:17292431 valproic acid decreases expression ISO INSIG1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of INSIG1 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO INSIG1 (Homo sapiens) 6480464 Valproic Acid affects the expression of INSIG1 mRNA CTD PMID:25979313 valproic acid decreases expression ISO Insig1 (Mus musculus) 6480464 Valproic Acid results in decreased expression of INSIG1 mRNA CTD PMID:22045034 valproic acid decreases methylation ISO INSIG1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of INSIG1 gene CTD PMID:29154799 vanadium atom decreases expression ISO INSIG1 (Homo sapiens) 6480464 Vanadium results in decreased expression of INSIG1 mRNA CTD PMID:19000753 vanadium(0) decreases expression ISO INSIG1 (Homo sapiens) 6480464 Vanadium results in decreased expression of INSIG1 mRNA CTD PMID:19000753 vancomycin increases expression ISO Insig1 (Mus musculus) 6480464 Vancomycin results in increased expression of INSIG1 mRNA CTD PMID:18930951 vandetanib increases expression ISO INSIG1 (Homo sapiens) 6480464 vandetanib results in increased expression of INSIG1 mRNA CTD PMID:16052530 vanillin decreases expression ISO INSIG1 (Homo sapiens) 6480464 vanillin results in decreased expression of INSIG1 mRNA CTD PMID:17178418 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of INSIG1 mRNA CTD PMID:22570695 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of INSIG1 mRNA CTD PMID:23034163 vorinostat decreases expression ISO INSIG1 (Homo sapiens) 6480464 vorinostat results in decreased expression of INSIG1 mRNA CTD PMID:27188386 zinc atom multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of INSIG1 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO INSIG1 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of INSIG1 mRNA CTD PMID:18593933 zoledronic acid increases expression ISO INSIG1 (Homo sapiens) 6480464 zoledronic acid results in increased expression of INSIG1 mRNA CTD PMID:24714768 and PMID:25596134