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Gene: Insig1 (insulin induced gene 1) Rattus norvegicus
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Symbol: Insig1
Name: insulin induced gene 1
Description: Involved in cellular response to insulin stimulus; response to estradiol; and response to fatty acid. Predicted to localize to the SREBP-SCAP-Insig complex. Biomarker of fatty liver disease. Orthologous to human INSIG1 (insulin induced gene 1); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; INTERACTS WITH (S)-nicotine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-benzylpiperazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: growth response protein (CL-6); immediate-early protein CL-6; INSIG-1; insulin-induced gene 1 protein; insulin-induced growth response protein CL-6; LOC64194
Orthologs:
Homo sapiens (human) : INSIG1 (insulin induced gene 1)  HGNC  Alliance
Mus musculus (house mouse) : Insig1 (insulin induced gene 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Insig1 (insulin induced gene 1)
Pan paniscus (bonobo/pygmy chimpanzee) : INSIG1 (insulin induced gene 1)
Canis lupus familiaris (dog) : INSIG1 (insulin induced gene 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insig1 (insulin induced gene 1)
Sus scrofa (pig) : INSIG1 (insulin induced gene 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04342,302 - 350,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4342,302 - 350,515 (+)Ensembl
Rnor_5.04337,389 - 345,602 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,577,468 - 2,585,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.142,577,467 - 2,585,682 (-)NCBI
Celera42,956,778 - 2,964,992 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Insig1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708457
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.