(+)-artemisinin multiple interactions ISO RGD:1315401 6480464 artemisinine inhibits the reaction [Simvastatin results in increased phosphorylation of CHUK protein] CTD PMID:18463201 (+)-Tetrandrine multiple interactions EXP 6480464 tetrandrine inhibits the reaction [IL1B protein results in increased phosphorylation of CHUK protein], tetrandrine inhibits the reaction [TNF protein results in increased expression of CHUK protein] CTD PMID:17201889 , PMID:22001142 (R)-mevalonic acid multiple interactions ISO RGD:1315401 6480464 Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased activity of and results in increased phosphorylation of CHUK protein] CTD PMID:17322126 (R)-mevalonic acid decreases phosphorylation ISO RGD:1315401 6480464 Mevalonic Acid results in decreased phosphorylation of CHUK protein CTD PMID:17322126 (Z)-ligustilide multiple interactions ISO RGD:1315402 6480464 ligustilide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of CHUK protein] CTD PMID:33130971 1'-acetoxychavicol acetate multiple interactions ISO RGD:1315401 6480464 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15905586 1,2-dimethylhydrazine decreases expression ISO RGD:1315402 6480464 1, 2-Dimethylhydrazine results in decreased expression of CHUK mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:1315402 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of CHUK mRNA] CTD PMID:22206623 1,4-dithiothreitol multiple interactions ISO RGD:1315402 6480464 Dithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of CHUK protein], Dithiothreitol inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of CHUK protein]] CTD PMID:17067557 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:1315401 6480464 15-deoxy-delta12, 14-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] CTD PMID:15498850 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 15-deoxy-delta12, 14-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein] CTD PMID:22245093 17alpha-ethynylestradiol multiple interactions ISO RGD:1315402 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHUK mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:1315401 6480464 Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein] CTD PMID:26220752 17beta-estradiol decreases expression ISO RGD:1315401 6480464 Estradiol results in decreased expression of CHUK mRNA CTD PMID:23094148 17beta-estradiol affects expression ISO RGD:1315401 6480464 Estradiol affects the expression of CHUK mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1315402 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CHUK mRNA more ... CTD PMID:17942748 , PMID:24519526 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CHUK mRNA CTD PMID:26232522 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1315401 6480464 Tetrachlorodibenzodioxin promotes the reaction [CHUK protein binds to IL6 promoter] CTD PMID:20511231 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1315402 6480464 Tetrachlorodibenzodioxin affects the expression of CHUK mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1315402 6480464 Tetrachlorodibenzodioxin results in increased expression of CHUK mRNA CTD PMID:21354282 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of CHUK mRNA CTD PMID:21346803 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of CHUK protein] CTD PMID:22310181 2-amino-2-deoxy-D-galactopyranose increases phosphorylation EXP 6480464 Galactosamine results in increased phosphorylation of CHUK protein CTD PMID:22310181 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:1315401 6480464 Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein CTD PMID:20113495 2-amino-2-deoxy-D-glucopyranose decreases activity ISO RGD:1315401 6480464 Glucosamine analog results in decreased activity of CHUK protein CTD PMID:20113495 2-deoxy-D-glucose affects localization ISO RGD:1315401 6480464 Deoxyglucose analog affects the localization of CHUK protein CTD PMID:27931795 3,3'-diindolylmethane decreases phosphorylation ISO RGD:1315401 6480464 3, 3'-diindolylmethane results in decreased phosphorylation of CHUK protein CTD PMID:22290291 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of CHUK mRNA CTD PMID:30071829 3-phenylprop-2-enal decreases phosphorylation EXP 6480464 cinnamic aldehyde results in decreased phosphorylation of CHUK protein CTD PMID:17486422 [6]-Shogaol multiple interactions ISO RGD:1315401 6480464 shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein] CTD PMID:23899529 acetylsalicylic acid multiple interactions ISO RGD:1315401 6480464 Aspirin inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 acetylsalicylic acid decreases phosphorylation EXP 6480464 Aspirin results in decreased phosphorylation of CHUK protein CTD PMID:16310244 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of CHUK mRNA CTD PMID:28959563 acrylamide increases expression ISO RGD:1315401 6480464 Acrylamide results in increased expression of CHUK mRNA CTD PMID:32763439 aldehydo-D-glucosamine multiple interactions ISO RGD:1315401 6480464 Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein CTD PMID:20113495 aldehydo-D-glucosamine decreases activity ISO RGD:1315401 6480464 Glucosamine analog results in decreased activity of CHUK protein CTD PMID:20113495 aldehydo-D-ribose increases phosphorylation ISO RGD:1315402 6480464 Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 alpinumisoflavone decreases expression ISO RGD:1315401 6480464 alpinumisoflavone results in decreased expression of CHUK protein CTD PMID:23850732 aniline increases expression EXP 6480464 aniline results in increased expression of CHUK protein CTD PMID:18420242 aniline increases phosphorylation EXP 6480464 aniline results in increased phosphorylation of CHUK protein CTD PMID:18420242 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [sodium arsenite results in increased phosphorylation of CHUK protein] CTD PMID:19616567 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of CHUK protein] CTD PMID:25935278 aristolochic acid decreases expression ISO RGD:1315401 6480464 aristolochic acid I results in decreased expression of CHUK mRNA CTD PMID:33212167 arjunolic acid multiple interactions ISO RGD:1315402 6480464 arjunolic acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CHUK protein] CTD PMID:21420465 arsenite(3-) multiple interactions ISO RGD:1315401 6480464 arsenite inhibits the reaction [MAP3K14 protein results in increased activity of CHUK protein] CTD PMID:10967126 arsenite(3-) decreases expression ISO RGD:1315402 6480464 arsenite results in decreased expression of CHUK mRNA CTD PMID:33053406 arsenous acid multiple interactions ISO RGD:1315401 6480464 [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein, Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein CTD PMID:23949314 arsenous acid decreases expression ISO RGD:1315401 6480464 Arsenic Trioxide results in decreased expression of CHUK protein CTD PMID:22384180 astragaloside IV multiple interactions ISO RGD:1315401 6480464 astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein] CTD PMID:33285147 atorvastatin calcium multiple interactions ISO RGD:1315402 6480464 Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of CHUK protein] CTD PMID:19800637 atrazine decreases expression ISO RGD:1315401 6480464 Atrazine results in decreased expression of CHUK mRNA CTD PMID:22378314 auranofin multiple interactions ISO RGD:1315401 6480464 Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:10820281 auranofin multiple interactions ISO RGD:1315402 6480464 Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein], Auranofin inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 Aurothioglucose multiple interactions ISO RGD:1315402 6480464 Aurothioglucose inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 benzo[a]pyrene decreases expression ISO RGD:1315402 6480464 Benzoapyrene results in decreased expression of CHUK mRNA CTD PMID:21569818 benzo[a]pyrene multiple interactions ISO RGD:1315401 6480464 [Benzoapyrene co-treated with resveratrol] results in decreased expression of CHUK mRNA, [Benzoapyrene co-treated with thymoquinone] results in decreased expression of CHUK mRNA CTD PMID:24289642 Berbamine decreases expression ISO RGD:1315401 6480464 berbamine results in decreased expression of CHUK protein CTD PMID:19960011 beta-D-glucosamine multiple interactions ISO RGD:1315401 6480464 Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein CTD PMID:20113495 beta-D-glucosamine decreases activity ISO RGD:1315401 6480464 Glucosamine analog results in decreased activity of CHUK protein CTD PMID:20113495 beta-D-glucosamine 6-sulfate multiple interactions ISO RGD:1315401 6480464 glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of CHUK protein] CTD PMID:21877189 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CHUK mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CHUK mRNA CTD PMID:27571134 bortezomib increases activity ISO RGD:1315401 6480464 Bortezomib results in increased activity of CHUK protein CTD PMID:24085292 bortezomib increases expression ISO RGD:1315401 6480464 Bortezomib results in increased expression of CHUK mRNA CTD PMID:20471514 cadmium atom decreases activity EXP 6480464 Cadmium results in decreased activity of CHUK protein CTD PMID:16478757 cadmium atom multiple interactions EXP 6480464 MAP3K7 protein affects the reaction [Cadmium results in increased phosphorylation of CHUK protein] CTD PMID:32693121 cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of CHUK protein CTD PMID:32693121 cadmium dichloride multiple interactions ISO RGD:1315402 6480464 arjunolic acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CHUK protein] CTD PMID:21420465 cadmium dichloride decreases activity EXP 6480464 Cadmium Chloride results in decreased activity of CHUK protein CTD PMID:16478757 cadmium dichloride increases phosphorylation ISO RGD:1315402 6480464 Cadmium Chloride results in increased phosphorylation of CHUK protein CTD PMID:21420465 cadmium selenide multiple interactions ISO RGD:1315401 6480464 [cadmium selenide co-treated with zinc sulfide] affects the expression of CHUK mRNA CTD PMID:22342292 carbon nanotube increases expression ISO RGD:1315402 6480464 Nanotubes, Carbon results in increased expression of CHUK mRNA CTD PMID:30081225 celastrol multiple interactions EXP 6480464 celastrol inhibits the reaction [Doxorubicin results in increased phosphorylation of CHUK protein] CTD PMID:30588110 celecoxib multiple interactions ISO RGD:1315401 6480464 Celecoxib inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 cerium trichloride increases expression ISO RGD:1315402 6480464 cerous chloride results in increased expression of CHUK mRNA, cerous chloride results in increased expression of CHUK protein CTD PMID:21656643 chloroquine decreases expression ISO RGD:1315401 6480464 Chloroquine results in decreased expression of CHUK protein CTD PMID:26116531 chromium(6+) increases activity ISO RGD:1315401 6480464 chromium hexavalent ion results in increased activity of CHUK protein CTD PMID:25448439 chromium(6+) multiple interactions ISO RGD:1315401 6480464 Luteolin inhibits the reaction [chromium hexavalent ion results in increased activity of CHUK protein] CTD PMID:25448439 cisplatin multiple interactions ISO RGD:1315401 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CHUK mRNA CTD PMID:27514524 cobalt dichloride multiple interactions ISO RGD:1315402 6480464 cobaltous chloride inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 crocidolite asbestos multiple interactions ISO RGD:1315401 6480464 Asbestos more ... CTD PMID:17322126 curcumin multiple interactions ISO RGD:1315401 6480464 Curcumin inhibits the reaction [TNF protein results in increased activity of CHUK protein], Curcumin inhibits the reaction [TNFSF11 protein results in increased activity of CHUK protein] CTD PMID:15129424 more ... curcumin decreases activity ISO RGD:1315401 6480464 Curcumin results in decreased activity of CHUK protein CTD PMID:16023083 , PMID:16219905 cyclosporin A increases expression ISO RGD:1315401 6480464 Cyclosporine results in increased expression of CHUK mRNA CTD PMID:25562108 D-ribofuranose increases phosphorylation ISO RGD:1315402 6480464 Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 Decursin multiple interactions ISO RGD:1315402 6480464 decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein] CTD PMID:31351099 deferiprone multiple interactions EXP 6480464 deferiprone inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]], deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] CTD PMID:17172471 deferiprone multiple interactions ISO RGD:1315401 6480464 Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein] CTD PMID:33285147 deoxynivalenol increases phosphorylation ISO RGD:1315401 6480464 deoxynivalenol results in increased phosphorylation of CHUK protein CTD PMID:20633634 dexamethasone multiple interactions ISO RGD:1315401 6480464 Dexamethasone inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 dextran sulfate increases expression ISO RGD:1315402 6480464 Dextran Sulfate results in increased expression of CHUK protein modified form CTD PMID:25472953 dextran sulfate multiple interactions ISO RGD:1315402 6480464 notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of CHUK protein modified form] CTD PMID:25472953 diarsenic trioxide multiple interactions ISO RGD:1315401 6480464 [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein, Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein CTD PMID:23949314 diarsenic trioxide decreases expression ISO RGD:1315401 6480464 Arsenic Trioxide results in decreased expression of CHUK protein CTD PMID:22384180 diclofenac multiple interactions ISO RGD:1315401 6480464 Diclofenac inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 diclofenac multiple interactions EXP 6480464 Diclofenac inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of CHUK protein] CTD PMID:25935278 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of CHUK mRNA, Cacodylic Acid results in increased expression of CHUK protein CTD PMID:26617437 doxorubicin increases phosphorylation ISO RGD:1315401 6480464 Doxorubicin results in increased phosphorylation of CHUK protein CTD PMID:18463201 , PMID:19746155 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of CHUK protein CTD PMID:30588110 doxorubicin multiple interactions EXP 6480464 celastrol inhibits the reaction [Doxorubicin results in increased phosphorylation of CHUK protein] CTD PMID:30588110 doxorubicin decreases expression ISO RGD:1315401 6480464 Doxorubicin results in decreased expression of CHUK mRNA CTD PMID:29803840 doxorubicin multiple interactions ISO RGD:1315401 6480464 Simvastatin promotes the reaction [Doxorubicin results in increased phosphorylation of CHUK protein] CTD PMID:18463201 Evodiamine multiple interactions ISO RGD:1315401 6480464 evodiamine inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15710601 filipin III multiple interactions EXP 6480464 Filipin inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]], Filipin inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] CTD PMID:17172471 flutamide increases expression EXP 6480464 Flutamide results in increased expression of CHUK mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1315402 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of CHUK mRNA] CTD PMID:22206623 fructose increases phosphorylation EXP 6480464 Fructose results in increased phosphorylation of CHUK protein CTD PMID:24491314 fructose multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in increased phosphorylation of CHUK protein] CTD PMID:24491314 fulvestrant multiple interactions ISO RGD:1315401 6480464 fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein] CTD PMID:26220752 gallic acid multiple interactions ISO RGD:1315401 6480464 Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:21420233 gallic acid decreases activity ISO RGD:1315401 6480464 Gallic Acid results in decreased activity of CHUK protein CTD PMID:22387266 geldanamycin increases degradation ISO RGD:1315401 6480464 geldanamycin results in increased degradation of CHUK protein CTD PMID:15930313 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CHUK mRNA CTD PMID:22061828 ginsenoside Re multiple interactions ISO RGD:1315402 6480464 ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:17885204 glutathione multiple interactions ISO RGD:1315402 6480464 Glutathione inhibits the reaction [Melitten binds to and results in decreased activity of CHUK protein], Glutathione inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of CHUK protein]] CTD PMID:17067557 graphene oxide decreases expression ISO RGD:1315401 6480464 graphene oxide results in decreased expression of CHUK protein CTD PMID:30239936 homoeriodictyol multiple interactions ISO RGD:1315402 6480464 homoeriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:31850465 hydrogen peroxide multiple interactions ISO RGD:1315402 6480464 Hydrogen Peroxide inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of CHUK protein]] CTD PMID:17067557 ibuprofen decreases activity ISO RGD:1315401 6480464 Ibuprofen results in decreased activity of CHUK protein CTD PMID:10602496 ibuprofen multiple interactions ISO RGD:1315401 6480464 Ibuprofen inhibits the reaction [TNF protein results in increased activity of CHUK protein], Ibuprofen results in decreased activity of [TNF protein results in increased activity of CHUK protein] CTD PMID:10602496 , PMID:15489888 indole-3-methanol multiple interactions ISO RGD:1315401 6480464 indole-3-carbinol inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15811958 ionomycin multiple interactions ISO RGD:1315402 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein, Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein] CTD PMID:10820281 iron atom multiple interactions EXP 6480464 deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] more ... CTD PMID:17172471 iron atom multiple interactions ISO RGD:1315401 6480464 [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein more ... CTD PMID:33285147 iron dextran multiple interactions ISO RGD:1315401 6480464 [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein more ... CTD PMID:33285147 iron(0) multiple interactions ISO RGD:1315401 6480464 [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein more ... CTD PMID:33285147 iron(0) multiple interactions EXP 6480464 deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] more ... CTD PMID:17172471 iron(2+) sulfate (anhydrous) multiple interactions EXP 6480464 deferiprone inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]] more ... CTD PMID:17172471 isoliquiritigenin multiple interactions ISO RGD:1315402 6480464 isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of CHUK protein] CTD PMID:18295200 kaempferol decreases phosphorylation ISO RGD:1315401 6480464 kaempferol results in decreased phosphorylation of CHUK protein CTD PMID:17184768 kaempferol multiple interactions ISO RGD:1315402 6480464 kaempferol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:30769083 L-1,4-dithiothreitol multiple interactions ISO RGD:1315402 6480464 Dithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of CHUK protein], Dithiothreitol inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of CHUK protein]] CTD PMID:17067557 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of CHUK protein CTD PMID:16547843 lead nitrate increases phosphorylation ISO RGD:1315402 6480464 lead nitrate results in increased phosphorylation of CHUK protein CTD PMID:23451106 lead nitrate multiple interactions ISO RGD:1315402 6480464 mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of CHUK protein] CTD PMID:23451106 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of CHUK protein CTD PMID:16547843 lead(2+) decreases expression EXP 6480464 Lead results in decreased expression of CHUK protein CTD PMID:16547843 lipopolysaccharide multiple interactions ISO RGD:1315401 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] more ... CTD PMID:11739238 more ... lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of CHUK protein CTD PMID:15466358 , PMID:21893401 lipopolysaccharide multiple interactions EXP 6480464 wuzi yanzong analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:21893401 lipopolysaccharide increases phosphorylation ISO RGD:1315402 6480464 Lipopolysaccharides results in increased phosphorylation of CHUK protein CTD PMID:18789402 more ... lipopolysaccharide increases activity ISO RGD:1315402 6480464 Lipopolysaccharides results in increased activity of CHUK protein CTD PMID:10820281 lipopolysaccharide multiple interactions ISO RGD:1315402 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] more ... CTD PMID:10820281 more ... lipopolysaccharide increases phosphorylation ISO RGD:1315401 6480464 Lipopolysaccharides results in increased phosphorylation of CHUK protein CTD PMID:18789402 , PMID:20715105 lipopolysaccharide increases activity ISO RGD:1315401 6480464 Lipopolysaccharides results in increased activity of CHUK protein CTD PMID:11739238 luteolin multiple interactions ISO RGD:1315401 6480464 Luteolin inhibits the reaction [chromium hexavalent ion results in increased activity of CHUK protein] CTD PMID:25448439 LY294002 multiple interactions ISO RGD:1315401 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:18789402 LY294002 decreases phosphorylation ISO RGD:1315401 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of CHUK protein CTD PMID:20386985 LY294002 multiple interactions ISO RGD:1315402 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:18789402 maneb multiple interactions ISO RGD:1315402 6480464 [Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein, Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein] CTD PMID:29568078 manganese(II) chloride multiple interactions EXP 6480464 15-deoxy-delta12, 14-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein] CTD PMID:22245093 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of CHUK protein CTD PMID:22245093 mangiferin multiple interactions ISO RGD:1315401 6480464 mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:21420233 mangiferin multiple interactions ISO RGD:1315402 6480464 mangiferin inhibits the reaction [lead nitrate results in increased phosphorylation of CHUK protein] CTD PMID:23451106 mangiferin multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of CHUK protein] CTD PMID:22310181 masoprocol multiple interactions ISO RGD:1315401 6480464 Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of CHUK protein modified form] CTD PMID:17395008 melittin multiple interactions ISO RGD:1315402 6480464 [Melitten inhibits the reaction [Nitroprusside results in increased phosphorylation of CHUK protein]] which results in decreased localization of NFKB1 protein more ... CTD PMID:17067557 , PMID:21969711 melittin affects binding ISO RGD:1315402 6480464 Melitten binds to CHUK protein CTD PMID:17067557 melittin multiple interactions ISO RGD:1315401 6480464 [Melitten inhibits the reaction [Nitroprusside results in increased phosphorylation of CHUK protein]] which results in decreased localization of NFKB1 protein more ... CTD PMID:17067557 melphalan affects phosphorylation ISO RGD:1315401 6480464 Melphalan affects the phosphorylation of CHUK protein CTD PMID:19934314 mercury dichloride increases phosphorylation ISO RGD:1315402 6480464 Mercuric Chloride results in increased phosphorylation of CHUK protein CTD PMID:21373768 mercury dichloride multiple interactions ISO RGD:1315402 6480464 Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 metformin decreases expression ISO RGD:1315401 6480464 Metformin results in decreased expression of CHUK mRNA CTD PMID:32589349 metformin multiple interactions ISO RGD:1315401 6480464 [Metformin co-treated with Pioglitazone] results in decreased expression of CHUK mRNA CTD PMID:32589349 monosodium L-glutamate increases phosphorylation ISO RGD:1315402 6480464 Sodium Glutamate results in increased phosphorylation of CHUK protein CTD PMID:19800637 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of CHUK mRNA CTD PMID:28954212 monosodium L-glutamate multiple interactions ISO RGD:1315402 6480464 Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of CHUK protein] CTD PMID:19800637 N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide multiple interactions EXP 6480464 N-3, 5-bistrifluoromethylphenyl-5-chloro-2-hydroxybenzamide inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:22207076 N-acetyl-L-cysteine decreases activity ISO RGD:1315401 6480464 Acetylcysteine results in decreased activity of CHUK protein CTD PMID:17395010 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases activity ISO RGD:1315401 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CHUK protein CTD PMID:24085292 N-ethylmaleimide multiple interactions ISO RGD:1315402 6480464 Ethylmaleimide inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 N-nitrosodiethylamine increases activity ISO RGD:1315402 6480464 Diethylnitrosamine results in increased activity of CHUK protein CTD PMID:15989949 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of CHUK mRNA CTD PMID:24136188 Neferine multiple interactions EXP 6480464 neferine inhibits the reaction [Aluminum Chloride results in decreased expression of CHUK protein] CTD PMID:31860774 nickel dichloride multiple interactions ISO RGD:1315402 6480464 CHUK protein affects the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein] CTD PMID:18792914 nickel dichloride affects response to substance ISO RGD:1315402 6480464 CHUK protein affects the susceptibility to nickel chloride CTD PMID:18792914 niclosamide multiple interactions ISO RGD:1315401 6480464 Niclosamide results in decreased phosphorylation of and affects the localization of CHUK protein CTD PMID:26116531 nicotinamide increases activity ISO RGD:1315401 6480464 Niacinamide results in increased activity of CHUK protein CTD PMID:24962570 nicotinamide multiple interactions ISO RGD:1315401 6480464 resveratrol inhibits the reaction [Niacinamide results in increased activity of CHUK protein] CTD PMID:24962570 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of CHUK mRNA CTD PMID:24136188 nitroprusside increases phosphorylation ISO RGD:1315402 6480464 Nitroprusside results in increased phosphorylation of CHUK protein CTD PMID:17067557 nitroprusside multiple interactions ISO RGD:1315401 6480464 [Melitten inhibits the reaction [Nitroprusside results in increased phosphorylation of CHUK protein]] which results in decreased localization of NFKB1 protein more ... CTD PMID:17067557 nitroprusside increases phosphorylation ISO RGD:1315401 6480464 Nitroprusside results in increased phosphorylation of CHUK protein CTD PMID:17067557 nitroprusside multiple interactions ISO RGD:1315402 6480464 [Melitten inhibits the reaction [Nitroprusside results in increased phosphorylation of CHUK protein]] which results in decreased localization of NFKB1 protein more ... CTD PMID:17067557 notoginsenoside R1 multiple interactions ISO RGD:1315402 6480464 notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of CHUK protein modified form] CTD PMID:25472953 ozone increases phosphorylation EXP 6480464 Ozone results in increased phosphorylation of CHUK protein CTD PMID:33383130 Paeonol multiple interactions ISO RGD:1315402 6480464 [paeonol inhibits the reaction [[CHUK protein binds to IKBKB protein] which results in increased degradation of NFKBIA protein]] which affects the localization of NFKB1 protein more ... CTD PMID:22542583 paracetamol affects expression ISO RGD:1315402 6480464 Acetaminophen affects the expression of CHUK mRNA CTD PMID:17562736 paraquat multiple interactions ISO RGD:1315402 6480464 [Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein, Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein] CTD PMID:29568078 parthenolide multiple interactions ISO RGD:1315401 6480464 parthenolide inhibits the reaction [Simvastatin results in increased phosphorylation of CHUK protein] CTD PMID:18463201 phenobarbital affects expression ISO RGD:1315402 6480464 Phenobarbital affects the expression of CHUK mRNA CTD PMID:23091169 phenylbutazone multiple interactions ISO RGD:1315401 6480464 Phenylbutazone inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:1315401 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein CTD PMID:26220752 phorbol 13-acetate 12-myristate increases expression ISO RGD:1315402 6480464 Tetradecanoylphorbol Acetate results in increased expression of CHUK protein CTD PMID:31351099 phorbol 13-acetate 12-myristate increases expression ISO RGD:1315401 6480464 Tetradecanoylphorbol Acetate results in increased expression of CHUK protein CTD PMID:21035309 phorbol 13-acetate 12-myristate increases activity ISO RGD:1315402 6480464 Tetradecanoylphorbol Acetate results in increased activity of CHUK protein CTD PMID:16474181 phorbol 13-acetate 12-myristate increases activity ISO RGD:1315401 6480464 Tetradecanoylphorbol Acetate results in increased activity of CHUK protein CTD PMID:15498850 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1315402 6480464 3-4-methylphenylsulfonyl-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] more ... CTD PMID:10820281 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1315401 6480464 15-deoxy-delta12 more ... CTD PMID:15498850 more ... pioglitazone multiple interactions ISO RGD:1315401 6480464 [Metformin co-treated with Pioglitazone] results in decreased expression of CHUK mRNA CTD PMID:32589349 pirinixic acid decreases expression ISO RGD:1315402 6480464 pirinixic acid results in decreased expression of CHUK mRNA CTD PMID:18445702 pirinixic acid increases expression ISO RGD:1315402 6480464 pirinixic acid results in increased expression of CHUK mRNA CTD PMID:23811191 pyrrolidine dithiocarbamate multiple interactions ISO RGD:1315401 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:11739238 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in increased phosphorylation of CHUK protein], Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] CTD PMID:16177186 , PMID:24491314 quercetin decreases phosphorylation ISO RGD:1315401 6480464 Quercetin results in decreased phosphorylation of CHUK protein CTD PMID:17184768 , PMID:20386985 quercetin multiple interactions ISO RGD:1315401 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CHUK mRNA more ... CTD PMID:20386985 more ... quercetin decreases expression ISO RGD:1315401 6480464 Quercetin results in decreased expression of CHUK mRNA CTD PMID:21632981 , PMID:23727915 quercetin multiple interactions ISO RGD:1315402 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:16171798 resiquimod multiple interactions ISO RGD:1315401 6480464 2-aminocarbonylamino-5-4-fluorophenyl-3-thiophenecarboxamide inhibits the reaction [resiquimod results in increased phosphorylation of and results in increased degradation of CHUK protein], 5-7-oxo-zeaenol inhibits the reaction [resiquimod results in increased phosphorylation of and results in increased degradation of CHUK protein] CTD PMID:28924041 resiquimod multiple interactions ISO RGD:1315402 6480464 resiquimod results in increased phosphorylation of and results in increased degradation of CHUK protein CTD PMID:28924041 resveratrol multiple interactions ISO RGD:1315401 6480464 [Benzoapyrene co-treated with resveratrol] results in decreased expression of CHUK mRNA more ... CTD PMID:15489888 more ... resveratrol decreases phosphorylation ISO RGD:1315401 6480464 resveratrol results in decreased phosphorylation of CHUK protein CTD PMID:25692777 resveratrol multiple interactions ISO RGD:1315402 6480464 resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein], resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] CTD PMID:16474181 , PMID:22118570 rocaglamide decreases expression ISO RGD:1315401 6480464 rocaglamide results in decreased expression of CHUK protein CTD PMID:31433962 rotenone multiple interactions ISO RGD:1315401 6480464 Rotenone inhibits the reaction [FN1 protein modified form results in increased expression of CHUK protein modified form] CTD PMID:17395008 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of CHUK protein] CTD PMID:19616567 silver atom increases expression ISO RGD:1315401 6480464 Silver results in increased expression of CHUK mRNA CTD PMID:22342292 silver(0) increases expression ISO RGD:1315401 6480464 Silver results in increased expression of CHUK mRNA CTD PMID:22342292 simvastatin multiple interactions ISO RGD:1315401 6480464 artemisinine inhibits the reaction [Simvastatin results in increased phosphorylation of CHUK protein] more ... CTD PMID:18463201 simvastatin increases expression ISO RGD:1315402 6480464 Simvastatin results in increased expression of CHUK mRNA CTD PMID:19262002 simvastatin increases phosphorylation ISO RGD:1315401 6480464 Simvastatin results in increased phosphorylation of CHUK protein CTD PMID:18463201 sodium arsenate increases expression ISO RGD:1315402 6480464 sodium arsenate results in increased expression of CHUK mRNA CTD PMID:21795629 sodium arsenite increases activity ISO RGD:1315401 6480464 sodium arsenite results in increased activity of CHUK protein CTD PMID:11835400 sodium arsenite decreases expression ISO RGD:1315401 6480464 sodium arsenite results in decreased expression of CHUK mRNA, sodium arsenite results in decreased expression of CHUK protein CTD PMID:29528074 sodium arsenite multiple interactions ISO RGD:1315402 6480464 [TRP53 gene mutant form affects the susceptibility to sodium arsenite] which results in decreased phosphorylation of CHUK protein CTD PMID:29944914 sodium arsenite decreases expression ISO RGD:1315402 6480464 sodium arsenite results in decreased expression of CHUK mRNA CTD PMID:31233874 sodium arsenite increases phosphorylation ISO RGD:1315401 6480464 sodium arsenite results in increased phosphorylation of CHUK protein CTD PMID:24570342 sodium arsenite multiple interactions ISO RGD:1315401 6480464 LCN2 mutant form inhibits the reaction [sodium arsenite results in increased phosphorylation of CHUK protein] CTD PMID:24570342 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of CHUK protein CTD PMID:19616567 sodium arsenite increases expression ISO RGD:1315402 6480464 sodium arsenite results in increased expression of CHUK mRNA CTD PMID:19822182 sodium arsenite multiple interactions EXP 6480464 PS1145 inhibits the reaction [sodium arsenite results in increased phosphorylation of CHUK protein] more ... CTD PMID:19616567 sodium aurothiomalate multiple interactions ISO RGD:1315402 6480464 Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 sodium dichromate multiple interactions ISO RGD:1315402 6480464 sodium bichromate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 streptozocin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] CTD PMID:16177186 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of CHUK protein CTD PMID:16177186 succimer multiple interactions ISO RGD:1315402 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of CHUK mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CHUK mRNA CTD PMID:21641980 , PMID:26378955 sulindac multiple interactions ISO RGD:1315401 6480464 Sulindac inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 sunitinib increases expression ISO RGD:1315401 6480464 Sunitinib results in increased expression of CHUK mRNA CTD PMID:31533062 tamoxifen multiple interactions ISO RGD:1315401 6480464 Tamoxifen inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [sodium arsenite results in increased phosphorylation of CHUK protein] CTD PMID:19616567 taurine multiple interactions ISO RGD:1315402 6480464 Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein] CTD PMID:29568078 testosterone affects expression ISO RGD:1315402 6480464 Testosterone affects the expression of CHUK mRNA CTD PMID:20403060 thalidomide multiple interactions EXP 6480464 Thalidomide inhibits the reaction [TNF protein results in increased expression of CHUK protein] CTD PMID:16604421 thioacetamide multiple interactions ISO RGD:1315402 6480464 Melitten inhibits the reaction [Thioacetamide results in increased phosphorylation of CHUK protein] CTD PMID:21969711 thioacetamide increases phosphorylation ISO RGD:1315402 6480464 Thioacetamide results in increased phosphorylation of CHUK protein CTD PMID:21969711 thiopental multiple interactions ISO RGD:1315401 6480464 Thiopental affects the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:12883408 thymoquinone multiple interactions ISO RGD:1315401 6480464 [Benzoapyrene co-treated with thymoquinone] results in decreased expression of CHUK mRNA CTD PMID:24289642 titanium dioxide decreases expression ISO RGD:1315401 6480464 titanium dioxide results in decreased expression of CHUK mRNA CTD PMID:22342292 titanium dioxide increases expression ISO RGD:1315402 6480464 titanium dioxide results in increased expression of CHUK protein CTD PMID:28646487 trimethyltin increases expression ISO RGD:1315402 6480464 trimethyltin results in increased expression of CHUK mRNA CTD PMID:21435392 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of CHUK mRNA CTD PMID:30589522 triptonide decreases expression ISO RGD:1315401 6480464 triptonide results in decreased expression of CHUK protein CTD PMID:31866380 Tylophorine increases activity ISO RGD:1315401 6480464 tylophorine analog results in increased activity of CHUK protein CTD PMID:19284764 valproic acid increases expression ISO RGD:1315401 6480464 Valproic Acid results in increased expression of CHUK mRNA CTD PMID:23179753 , PMID:29154799 vorinostat multiple interactions ISO RGD:1315401 6480464 [vorinostat co-treated with TNFSF10 protein] results in decreased expression of CHUK protein, vorinostat inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:16377638 , PMID:16450389 vorinostat decreases phosphorylation ISO RGD:1315401 6480464 vorinostat results in decreased phosphorylation of CHUK protein CTD PMID:17681667 wedelolactone multiple interactions EXP 6480464 wedelolactone inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:22207076 Y-27632 multiple interactions ISO RGD:1315401 6480464 Y 27632 results in increased activity of and results in increased phosphorylation of CHUK protein CTD PMID:17322126 zerumbone multiple interactions ISO RGD:1315401 6480464 zerumbone inhibits the reaction [CHUK protein results in increased activity of [NFKB1 protein binds to RELA protein]], zerumbone inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:16007145 zinc atom multiple interactions ISO RGD:1315401 6480464 Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein] CTD PMID:21035309 zinc sulfate multiple interactions ISO RGD:1315402 6480464 Zinc Sulfate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 zinc(0) multiple interactions ISO RGD:1315401 6480464 Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein] CTD PMID:21035309
