Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dpysl2 (dihydropyrimidinase-like 2) Rattus norvegicus
Symbol: Dpysl2
Name: dihydropyrimidinase-like 2
Description: Predicted to have hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; identical protein binding activity; and protein kinase binding activity. Involved in several processes, including nervous system development; positive regulation of glutamate secretion; and response to amphetamine. Localizes to several cellular components, including growth cone; myelin sheath; and neuronal cell body. Colocalizes with terminal bouton. Biomarker of brain ischemia; hypothyroidism; and status epilepticus. Orthologous to human DPYSL2 (dihydropyrimidinase like 2); INTERACTS WITH (+)-pilocarpine; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: collapsin response mediator protein 2; CRMP-2; Crmp2; dihydropyrimidinase-related protein 2; DRP-2; TOAD-64; turned on after division 64 kDa protein; turned on after division, 64 kDa protein
Homo sapiens (human) : DPYSL2 (dihydropyrimidinase like 2)  HGNC  Alliance
Mus musculus (house mouse) : Dpysl2 (dihydropyrimidinase-like 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpysl2 (dihydropyrimidinase like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DPYSL2 (dihydropyrimidinase like 2)
Canis lupus familiaris (dog) : DPYSL2 (dihydropyrimidinase like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpysl2 (dihydropyrimidinase like 2)
Sus scrofa (pig) : DPYSL2 (dihydropyrimidinase like 2)
Chlorocebus sabaeus (African green monkey) : DPYSL2 (dihydropyrimidinase like 2)
Heterocephalus glaber (naked mole-rat) : Dpysl2 (dihydropyrimidinase like 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01543,475,640 - 43,581,725 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1543,477,629 - 43,542,939 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01548,014,263 - 48,120,298 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41546,346,413 - 46,413,786 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11546,363,561 - 46,429,519 (-)NCBI
Celera1540,673,435 - 40,740,421 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dpysl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2517
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.