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Gene: PLD2 (phospholipase D2) Homo sapiens
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Symbol: PLD2
Name: phospholipase D2
Description: Predicted to have N-acylphosphatidylethanolamine-specific phospholipase D activity; phosphatidylinositol binding activity; and phospholipase D activity. Predicted to be involved in G protein-coupled receptor internalization and cell motility. Predicted to localize to brush border membrane. Biomarker of renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; PLD 2; PLD1C
Orthologs:
Mus musculus (house mouse) : Pld2 (phospholipase D2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pld2 (phospholipase D2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld2 (phospholipase D2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD2 (phospholipase D2)
Canis lupus familiaris (dog) : PLD2 (phospholipase D2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld2 (phospholipase D2)
Sus scrofa (pig) : PLD2 (phospholipase D2)
Chlorocebus sabaeus (African green monkey) : PLD2 (phospholipase D2)
Heterocephalus glaber (naked mole-rat) : Pld2 (phospholipase D2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl174,807,152 - 4,823,434 (+)EnsemblGRCh38hg38GRCh38
GRCh38174,807,152 - 4,823,432 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37174,710,396 - 4,726,727 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,657,378 - 4,673,694 (+)NCBINCBI36hg18NCBI36
Build 34174,657,391 - 4,673,694NCBI
Celera174,725,830 - 4,742,140 (+)NCBI
Cytogenetic Map17p13.2NCBI
HuRef174,598,848 - 4,615,181 (+)NCBIHuRef
CHM1_1174,719,366 - 4,735,679 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PLD2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733873
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.