1,2-dichloroethane increases expression ISO RGD:734077 6480464 ethylene dichloride results in increased expression of POLD1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO RGD:734077 6480464 1, 2-Dimethylhydrazine results in increased expression of POLD1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol affects expression ISO RGD:734077 6480464 Ethinyl Estradiol affects the expression of POLD1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:734077 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLD1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:734077 6480464 Ethinyl Estradiol results in increased expression of POLD1 mRNA CTD PMID:17942748 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of POLD1 mRNA CTD PMID:32145629 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO RGD:734076 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:734077 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLD1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of POLD1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:734076 6480464 Tetrachlorodibenzodioxin affects the expression of POLD1 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:734077 6480464 Tetrachlorodibenzodioxin affects the expression of POLD1 mRNA CTD PMID:21570461 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:734076 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of POLD1 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions ISO RGD:734076 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of POLD1 mRNA CTD PMID:28628672 4-hydroperoxycyclophosphamide decreases expression ISO RGD:734077 6480464 perfosfamide results in decreased expression of POLD1 mRNA CTD PMID:19429390 4-hydroxynon-2-enal decreases expression ISO RGD:734076 6480464 4-hydroxy-2-nonenal results in decreased expression of POLD1 mRNA CTD PMID:12419474 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of POLD1 mRNA CTD PMID:30047161 acetamide increases expression EXP 6480464 acetamide results in increased expression of POLD1 mRNA CTD PMID:31881176 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of POLD1 mRNA CTD PMID:28959563 Aflatoxin B2 alpha decreases methylation ISO RGD:734076 6480464 aflatoxin B2 results in decreased methylation of POLD1 intron CTD PMID:30157460 amitrole increases expression EXP 6480464 Amitrole results in increased expression of POLD1 mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of POLD1 mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of POLD1 mRNA CTD PMID:30779732 arsane affects methylation ISO RGD:734076 6480464 Arsenic affects the methylation of POLD1 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:734076 6480464 Arsenic affects the methylation of POLD1 gene CTD PMID:25304211 arsenous acid increases expression ISO RGD:734076 6480464 Arsenic Trioxide results in increased expression of POLD1 mRNA CTD PMID:29633893 arsenous acid multiple interactions ISO RGD:734076 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to POLD1 protein] CTD PMID:26598702 benzo[a]pyrene increases expression ISO RGD:734077 6480464 Benzo(a)pyrene results in increased expression of POLD1 mRNA CTD PMID:22228805 benzo[e]pyrene decreases methylation ISO RGD:734076 6480464 benzo(e)pyrene results in decreased methylation of POLD1 intron CTD PMID:30157460 Benzo[ghi]perylene increases expression ISO RGD:734076 6480464 1, 12-benzoperylene results in increased expression of POLD1 mRNA CTD PMID:31518672 bis(2-chloroethyl) sulfide decreases expression ISO RGD:734076 6480464 Mustard Gas results in decreased expression of POLD1 mRNA CTD PMID:25102026 bisphenol A increases expression ISO RGD:734077 6480464 bisphenol A results in increased expression of POLD1 mRNA CTD PMID:26063408 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of POLD1 mRNA CTD PMID:34947998 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of POLD1 mRNA CTD PMID:32145629 bisphenol A decreases expression ISO RGD:734076 6480464 bisphenol A results in decreased expression of POLD1 mRNA CTD PMID:29275510 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of POLD1 gene CTD PMID:28505145 calcitriol decreases expression ISO RGD:734076 6480464 Calcitriol results in decreased expression of POLD1 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:734076 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of POLD1 mRNA CTD PMID:21592394 cannabidiol decreases expression ISO RGD:734076 6480464 Cannabidiol results in decreased expression of POLD1 mRNA CTD PMID:36519830 carbon nanotube increases expression ISO RGD:734077 6480464 Nanotubes, Carbon analog results in increased expression of POLD1 mRNA CTD PMID:25554681 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of POLD1 mRNA CTD PMID:18500788 chlorpyrifos decreases expression ISO RGD:734077 6480464 Chlorpyrifos results in decreased expression of POLD1 mRNA CTD PMID:37019170 copper atom multiple interactions ISO RGD:734076 6480464 [NSC 689534 binds to Copper] which results in decreased expression of POLD1 mRNA CTD PMID:20971185 copper atom increases expression ISO RGD:734076 6480464 Copper results in increased expression of POLD1 mRNA CTD PMID:16391388 copper(0) multiple interactions ISO RGD:734076 6480464 [NSC 689534 binds to Copper] which results in decreased expression of POLD1 mRNA CTD PMID:20971185 copper(0) increases expression ISO RGD:734076 6480464 Copper results in increased expression of POLD1 mRNA CTD PMID:16391388 coumarin increases expression EXP 6480464 coumarin results in increased expression of POLD1 mRNA CTD PMID:18480146 coumestrol multiple interactions ISO RGD:734076 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 coumestrol increases expression ISO RGD:734076 6480464 Coumestrol results in increased expression of POLD1 mRNA CTD PMID:19167446 cyclosporin A decreases expression ISO RGD:734076 6480464 Cyclosporine results in decreased expression of POLD1 mRNA CTD PMID:25562108 dexamethasone multiple interactions ISO RGD:734076 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of POLD1 mRNA CTD PMID:28628672 Diallyl sulfide multiple interactions EXP 6480464 [allyl sulfide co-treated with Diethylstilbestrol] results in increased expression of POLD1 mRNA CTD PMID:17125941 Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of POLD1 mRNA CTD PMID:17125941 diarsenic trioxide multiple interactions ISO RGD:734076 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to POLD1 protein] CTD PMID:26598702 diarsenic trioxide increases expression ISO RGD:734076 6480464 Arsenic Trioxide results in increased expression of POLD1 mRNA CTD PMID:29633893 dibutyl phthalate decreases expression ISO RGD:734077 6480464 Dibutyl Phthalate results in decreased expression of POLD1 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of POLD1 mRNA CTD PMID:21266533 diethylstilbestrol multiple interactions EXP 6480464 [allyl sulfide co-treated with Diethylstilbestrol] results in increased expression of POLD1 mRNA CTD PMID:17125941 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of POLD1 mRNA CTD PMID:17720352 dioxygen decreases expression ISO RGD:734076 6480464 Oxygen deficiency results in decreased expression of POLD1 mRNA CTD PMID:26516004 doxorubicin decreases expression ISO RGD:734076 6480464 Doxorubicin results in decreased expression of POLD1 mRNA CTD PMID:29803840 Enterolactone multiple interactions ISO RGD:734076 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLD1 mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO RGD:734076 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of POLD1 protein CTD PMID:23301498 epoxiconazole decreases expression ISO RGD:734077 6480464 epoxiconazole results in decreased expression of POLD1 mRNA CTD PMID:35436446 furan increases expression EXP 6480464 furan results in increased expression of POLD1 mRNA CTD PMID:22079235 , PMID:25539665 guanine multiple interactions ISO RGD:734076 6480464 Guanine metabolite results in decreased activity of [POLD1 protein binds to POLD2 protein binds to POLD3 protein binds to POLD4 protein], Guanine metabolite results in decreased activity of [POLD1 protein binds to POLD2 protein binds to POLD4 protein] CTD PMID:26010525 guanine decreases activity ISO RGD:734076 6480464 Guanine metabolite results in decreased activity of POLD1 protein CTD PMID:26010525 hydrogen peroxide decreases expression ISO RGD:734076 6480464 Hydrogen Peroxide results in decreased expression of POLD1 mRNA CTD PMID:12419474 , PMID:21751221 hypochlorous acid decreases expression ISO RGD:734077 6480464 Hypochlorous Acid results in decreased expression of POLD1 mRNA CTD PMID:19376150 indometacin multiple interactions ISO RGD:734076 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of POLD1 mRNA CTD PMID:28628672 ivermectin decreases expression ISO RGD:734076 6480464 Ivermectin results in decreased expression of POLD1 protein CTD PMID:32959892 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of POLD1 mRNA CTD PMID:20080153 lead diacetate increases expression ISO RGD:734077 6480464 lead acetate results in increased expression of POLD1 mRNA CTD PMID:21829687 lead nitrate multiple interactions ISO RGD:734077 6480464 lead nitrate affects the reaction [POLD1 affects the expression of MT1 mRNA], lead nitrate affects the reaction [POLD1 affects the expression of MT2 mRNA] CTD PMID:11891201 lead(0) affects expression ISO RGD:734076 6480464 Lead affects the expression of POLD1 mRNA CTD PMID:28903495 methapyrilene decreases methylation ISO RGD:734076 6480464 Methapyrilene results in decreased methylation of POLD1 intron CTD PMID:30157460 methimazole increases expression EXP 6480464 Methimazole results in increased expression of POLD1 mRNA CTD PMID:30047161 miconazole increases expression EXP 6480464 Miconazole results in increased expression of POLD1 mRNA CTD PMID:22262564 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:734077 6480464 Ethylnitrosourea results in increased mutagenesis of POLD1 3' UTR, Ethylnitrosourea results in increased mutagenesis of POLD1 gene CTD PMID:27776689 N-nitrosodiethylamine increases expression ISO RGD:734077 6480464 Diethylnitrosamine results in increased expression of POLD1 mRNA CTD PMID:17854601 N-nitrosodiethylamine multiple interactions ISO RGD:734077 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA] CTD PMID:17854601 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of POLD1 mRNA CTD PMID:20360939 N-nitrosodiethylamine multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA] CTD PMID:20360939 ozone increases expression EXP 6480464 Ozone results in increased expression of POLD1 mRNA CTD PMID:16716893 ozone multiple interactions ISO RGD:734077 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of POLD1 mRNA CTD PMID:34911549 paracetamol affects expression ISO RGD:734077 6480464 Acetaminophen affects the expression of POLD1 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of POLD1 mRNA CTD PMID:33387578 phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA] CTD PMID:20360939 phenethyl isothiocyanate decreases expression ISO RGD:734076 6480464 phenethyl isothiocyanate results in decreased expression of POLD1 mRNA CTD PMID:26678675 phenobarbital affects expression ISO RGD:734076 6480464 Phenobarbital affects the expression of POLD1 mRNA CTD PMID:19159669 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of POLD1 mRNA CTD PMID:19162173 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of POLD1 mRNA CTD PMID:20726854 resveratrol multiple interactions ISO RGD:734076 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of POLD1 mRNA CTD PMID:19167446 sodium arsenite decreases expression ISO RGD:734076 6480464 sodium arsenite results in decreased expression of POLD1 mRNA CTD PMID:12377979 , PMID:12760830 sodium arsenite increases expression ISO RGD:734076 6480464 sodium arsenite results in increased expression of POLD1 mRNA CTD PMID:34032870 sodium dichromate increases expression ISO RGD:734077 6480464 sodium bichromate results in increased expression of POLD1 mRNA CTD PMID:22155349 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of POLD1 mRNA CTD PMID:12325037 , PMID:22110744 sodium fluoride increases expression ISO RGD:734077 6480464 Sodium Fluoride results in increased expression of POLD1 protein CTD PMID:28918527 Soman increases expression EXP 6480464 Soman results in increased expression of POLD1 mRNA CTD PMID:19281266 sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of POLD1 mRNA CTD PMID:30047161 sunitinib decreases expression ISO RGD:734076 6480464 Sunitinib results in decreased expression of POLD1 mRNA CTD PMID:31533062 taurine increases expression ISO RGD:734076 6480464 Taurine results in increased expression of POLD1 mRNA CTD PMID:16579726 tert-butyl hydroperoxide decreases expression ISO RGD:734076 6480464 tert-Butylhydroperoxide results in decreased expression of POLD1 mRNA CTD PMID:12419474 testosterone multiple interactions ISO RGD:734076 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of POLD1 mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:734076 6480464 Testosterone results in decreased expression of POLD1 mRNA CTD PMID:21592394 tetrachloromethane increases expression ISO RGD:734077 6480464 Carbon Tetrachloride results in increased expression of POLD1 mRNA CTD PMID:31919559 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of POLD1 mRNA CTD PMID:34492290 toluene 2,4-diisocyanate increases expression ISO RGD:734077 6480464 Toluene 2, 4-Diisocyanate results in increased expression of POLD1 mRNA CTD PMID:21404309 trimellitic anhydride increases expression ISO RGD:734077 6480464 trimellitic anhydride results in increased expression of POLD1 mRNA CTD PMID:19042947 troglitazone decreases expression ISO RGD:734076 6480464 troglitazone results in decreased expression of POLD1 mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO RGD:734077 6480464 trovafloxacin results in decreased expression of POLD1 mRNA CTD PMID:35537566 urethane decreases expression ISO RGD:734076 6480464 Urethane results in decreased expression of POLD1 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:734077 6480464 Valproic Acid affects the expression of POLD1 mRNA CTD PMID:17292431 vancomycin decreases expression ISO RGD:734077 6480464 Vancomycin results in decreased expression of POLD1 mRNA CTD PMID:18930951
